IRIS
GALEONE, ALDO
 Distribuzione geografica
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Continente #
NA - Nord America 2.827
EU - Europa 1.942
AS - Asia 561
AF - Africa 34
SA - Sud America 6
OC - Oceania 2
Totale 5.372
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Nazione #
US - Stati Uniti d'America 2.779
IT - Italia 911
CN - Cina 365
UA - Ucraina 274
FI - Finlandia 148
DE - Germania 128
IE - Irlanda 123
NL - Olanda 123
SE - Svezia 100
VN - Vietnam 95
GB - Regno Unito 50
CA - Canada 45
CI - Costa d'Avorio 30
IN - India 26
FR - Francia 21
JP - Giappone 19
TR - Turchia 17
PL - Polonia 13
BE - Belgio 10
HK - Hong Kong 9
IR - Iran 9
PT - Portogallo 8
SG - Singapore 8
ES - Italia 6
DK - Danimarca 5
CH - Svizzera 4
CL - Cile 4
CZ - Repubblica Ceca 4
PK - Pakistan 4
AM - Armenia 3
SD - Sudan 3
TW - Taiwan 3
AU - Australia 2
CR - Costa Rica 2
EE - Estonia 2
HU - Ungheria 2
KR - Corea 2
RU - Federazione Russa 2
SI - Slovenia 2
AT - Austria 1
BR - Brasile 1
MA - Marocco 1
MD - Moldavia 1
MT - Malta 1
MY - Malesia 1
PR - Porto Rico 1
PY - Paraguay 1
RO - Romania 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 5.372
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Città #
Chandler 637
Jacksonville 289
Napoli 214
Naples 160
Princeton 152
Millbury 140
Amsterdam 119
Ashburn 117
Woodbridge 113
Nanjing 110
Dong Ket 94
Boston 91
Beijing 74
Wilmington 70
Ann Arbor 69
Houston 58
Ottawa 42
Des Moines 35
Nanchang 34
Hebei 33
Norwalk 26
Shenyang 25
Dearborn 22
Jiaxing 22
Falls Church 21
Tianjin 18
Hangzhou 15
Boardman 14
Kronberg 14
Lawrence 14
Formia 13
Augusta 12
Poznan 11
Redwood City 11
Rome 11
Changsha 10
Marano Di Napoli 10
Washington 10
Caserta 9
Orange 9
Paris 9
Salerno 9
Seattle 9
Hong Kong 8
Los Angeles 8
Milan 8
Nocera Inferiore 8
Portici 7
Pune 7
Edinburgh 6
Aarhus 5
Cercola 5
Dublin 5
Guangzhou 5
New York 5
Padova 5
San Mateo 5
Turin 5
Arzano 4
Brussels 4
Indiana 4
Roccarainola 4
San Francisco 4
San Giorgio A Cremano 4
Simi Valley 4
Torre del Greco 4
Acerra 3
Ardabil 3
Aveiro 3
Bologna 3
Brno 3
Casalvieri 3
Casoria 3
Fairfield 3
Giugliano in Campania 3
Kunming 3
Leawood 3
Padula 3
Piana 3
Rohtak 3
San Giorgio 3
Singapore 3
Torino 3
Toronto 3
Vietri Sul Mare 3
Yerevan 3
Zhengzhou 3
Aszod 2
Bacoli 2
Bari 2
Capri 2
Casalgrande 2
Castello di Cisterna 2
Chatham 2
Crane Hill 2
Crispano 2
Curti 2
Ferrandina 2
Genova 2
Gragnano 2
Totale 3.188
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Nome #
Backbone modified TBA analogues endowed with antiproliferative activity 83
Pyrimido[5,4-d]Pyrimidine or pyrimidine derivates compounds and uses there of in the treatment of cancer 82
The ‘‘Janus face” of the thrombin binding aptamer: Investigating the anticoagulant and antiproliferative properties through straightforward chemical modifications 82
Ptaquiloside, the major carcinogen of bracken fern, in the pooled raw milk of healthy sheep and goats: an underestimated, global concern of food safety 76
Thrombin binding aptamer analogues containing inversion of polarity sites endowed with antiproliferative and anti-motility properties against Calu-6 cells 68
Metastatic group 3 medulloblastoma is driven by PRUNE1 targeting NME1-TGF-β-OTX2-SNAIL via PTEN inhibition. 66
Unusual Chair-Like G-Quadruplex Structures: Heterochiral TBA Analogues Containing Inversion of Polarity Sites 65
EFFECT OF THE INTRODUCTION OF AN A-RESIDUE INTO A QUADRUPLEX FORMING OLIGONUCLEOTIDE CONTAINING A 5'-5' POLARITY OF INVERSION SITE 65
Synthesis and characterization of tetra-end linked oligonucleotides capable of forming monomolecular G-quadruplex 63
1H-NMR study of the quadruplex [d(TGGGT)]4 containing a modified thymine 62
5-Hydroxymethyl-2′-Deoxyuridine Residues in the Thrombin Binding Aptamer: Investigating Anticoagulant Activity by Making a Tiny Chemical Modification 62
8-Methyl-2'-deoxyguanosine incorporation into parallel DNA quadruplex structures 60
The oxidative damage to the human telomere: effects of 5-hydroxymethyl-2'-deoxyuridine on telomeric G-quadruplex structures 58
Monomolecular G-quadruplex structures with inversion of polarity sites: new topologies and potentiality 58
Aptamers against the β-conglutin allergen: Insights into the behavior of the shortest multimeric (intra)molecular dna gquadruplex 57
Site-specific replacement of the thymine methyl group by fluorine in thrombin binding aptamer significantly improves structural stability and anticoagulant activity 56
Site specific replacements of a single loop nucleoside with a dibenzyl linker may switch the activity of TBA from anticoagulant to antiproliferative 55
UL3 mediated nucleolar stress pathway as a new mechanism of action of antiproliferative G-quadruplex TBA derivatives in colon cancer cells 54
Molecular Modelling Studies of Four Stranded Quadruplexes Containing a 3’-3’ or 5’-5’ Inversion of Polarity Site 53
A bunch-oligonucleotide forming stable monomolecular quadruplex containing a T-tetrad. 53
G-triplex stability in human telomeric DNA with epigenetic modification/oxidative damage to thymine 52
A topological classification of G-quadruplex structures 51
Solid phase synthesis of cyclic oligodeoxyribonucleotides intermolecular versus intramolecular coupling. 51
Automated solid phase synthesis of cyclic oligonucleotides: a further improvement 51
Aspetti dell’interazione tra la distamicina-A e la quadruplex [d(TGGGGT)]4 51
A MINI-LIBRARY OF TBA ANALOGUES CONTAINING 3'-3' AND 5'-5' INVERSION OF POLARITY SITES 50
Introduzione alla chimica organica 50
A novel pyrimidine tetrad contributing to stabilize tetramolecular G-quadruplex structures. 50
Design, synthesis, biophysical and biological studies on trisubstituted naphthalimides as G-Quadruplex ligands 49
Antiproliferative Effects of the Aptamer d(GGGT) 4 and Its Analogues with an Abasic-Site Mimic Loop on Different Cancer Cells 48
Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d(TGGGGT)]4 48
Synthesis of 3'-3'-linked pyrimidine oligonucleotides containing an acridine moiety for alternate strand triple helix formation 48
Discovering New G-Quadruplex DNA Catalysts in Enantioselective Sulfoxidation Reaction 48
nmr studies of the 5-(hydroxymethyl-2'-deoxyuridine containing tf1 binding site 47
Quadruplex DNA: structural features and potential applications 47
2'-Deoxy-8-(propyn-1-yl)adenosine-containing oligonucleotides: effects on stability of duplex and quadruplex structures 46
The abasic site lesions in the human telomeric sequence d[TA(G3T2A)3G3]: A thermodynamic point of view 46
Solid phase synthesis of 5-hydroxymethyluracil containing DNA 45
A new class of DNA quadruplexes formed by oligodeoxyribonucleotides containing a 3'-3' or 5'-5' inversion of polarity site 45
MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines 45
1H-NMR Study of the Quadruplex [d(TGGGT)]4 Containing a Modified Thymine 45
1H-NMR study of the interaction of distamycin A and netropsin with the parallel stranded tetraplex [d(TGGGGT)]4. 42
Syntheses of [1-15N]-2'-deoxyinosine, [4-15N]-2'-deoxyAICAR, and [1-15N]-2'-deoxyguanosine. 42
A NEW CLASS OF DNA QUADRUPLEX FORMED BY OLIGODEOXYRIBONUCLEOTIDES CONTAINING A 3’-3’ OR 5’-5’ INVERSION OF POLARITY SITE 42
The Introduction of Inversion of Polarity Sites in DNA G-Quadruplex Structures: Effects and Perspectives 42
A bunch-oligonucleotide forming stable monomolecular quadruplex containing a T-tetrad 41
Effects of 8-Methyl-2'-deoxyadenosine incorporation into quadruplex forming oligonucleotides 41
Synthesis, structural studies and biological properties of new TBA analogues containing an acyclic nucleotide 41
Expanding the potential of G-quadruplex structures: formation of a heterochiral TBA analogue 41
Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops 41
Synthesis and structural study of quadruplex structures containing 2'-deoxy-8-methyladenosine 40
Binding mode of distamycin to d(CGTACGTACG)2 in the 2:1 solution complex as determined by two-dimensional 1H NMR and molecular modeling studies 40
Studio 1H-NMR dell’ interazione tra la distamicina A e la netropsina con strutture di duplex e quadruplex DNA 40
Investigating the properties of TBA variants with twin thrombin binding domains 40
1H and 13C NMR spectra of imidazo[1,2-a]pyrazines. 39
PNA-DNA chimeras forming quadruplex structures 39
A NEW CLASS OF DNA QUADRUPLEX FORMED BY OLIGODEOXYRIBONUCLEOTIDES CONTAINING A 3'-3' OR 5'-5' INVERSION OF POLARITY SITE 39
Improved thrombin binding aptamer analogues containing inversion of polarity sites: structural effects of extra-residues at the ends 39
Easy chemical modifications to explore the ‘Janus face’ of TBA: anticoagulant vs antiproliferative properties. 39
Unusual monomolecular DNA Quadruplex structures using bunch-oligonucleotides 38
A straightforward modification in the thrombin binding aptamer improving stability, affinity to thrombin and nuclease resistance 38
Structural properties and anticoagulant/cytotoxic activities of heterochiral enantiomeric thrombin binding aptamer (TBA) derivatives 38
Synthesis and Characterization of monomolecular DNA G-quadruplex formed by tetra-end-linked oligonucleotides 37
Facile preparation of cyclic oligoribonucleotides. 37
Effects of abasic sites on structural, thermodynamic and kinetic properties of quadruplex structures. 37
Effects of 8-methylguanine on structure, stability and kinetics of formation of tetramolecular quadruplexes 37
Synthesis of 5-methylamino-2'-deoxyuridine derivatives. 36
Circular dichroism and termal melting differentiation of Hoechst 33258 bindings to the curved (A4T4) and non curved (T4A4) DNA sequences. 36
Interaction of Distamycin A and Netropsin with Quadruplex and Duplex Structures: a Comparative 1H-NMR study 36
Exploring the binding of d(GGGT)4 to the HIV-1 integrase: An approach to investigate G-quadruplex aptamer/target protein interactions. 36
Solid phase approach to the preparation of small circular DNA and RNA fragments 35
Structural study of four-stranded quadruplex structures containing 2'-deoxy-8-(propyn-1-yl)adenosine 35
Tetra-end-linked oligonucleotides forming DNA G-quadruplexes: a new class of aptamers showing anti-HIV activity 35
Exploring New Potential Anticancer Activities of the G-Quadruplexes Formed by [(GTG2T(G3T)3] and Its Derivatives with an Abasic Site Replacing Single Thymidine 35
Synthesis of triple helix forming oligonucleotides with a phenanthroline moiety into the 3’-3’ inversion site of polarity 34
Oligonucleotide delivery in cancer therapy 34
MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma. 34
Trisubstituted naphthalimides for DNA quadruplex binding selectivity: synthesis, NMR and biophysical studies 34
Chimica Organica 34
PRELIMINARY STRUCTURAL INVESTIGATIONS ON THE ANTI-HIV G-QUADRUPLEX FORMING OLIGONUCLEOTIDE TGGGAG AND ANALOGUES: EVIDENCE FOR THE PRESENCE OF AN A-TETRAD 34
Effect of gamma-hydroxypropano deoxyguanosine, the major acrolein-derived adduct, on monomolecular quadruplex structure of telomeric repeat d(TTAGGG) 4 34
Improved performances of catalytic G-quadruplexes (G4-DNAzymes) via the chemical modifications of the DNA backbone to provide Gquadruplexes with double 3′-external G-quartets 34
Synthesis and characterization of a bunchy oligonucleotide forming a monomolecular parallel quadruplex structure in solution. 33
Physico-chemical studies of quadruple helices of modified human telomeric DNA 33
From protein-protein interaction to E2 inhibitors leads: identification of peptide binding of UbcH10 33
Bunchy oligonucleotides forming new stable DNA quadruplex structure 33
Quadruplex DNA: structural features and potential applications 32
Thermodynamics of melting of the circular dumbbell d. 31
Slow conformational exchange in DNA minihairpin loops: a conformational study of the circular dumbbell d 31
EFFECTS OF THE SYN/ANTI EQUILIBRIUM MODULATION ON THE STRUCTURAL PROPERTIES OF TETRAMOLECULAR QUADRUPLEXES, 31
Heterochiral oligodeoxynucleotides forming quadruplex structures 31
NUOVI INIBITORI PIRIMIDO-PIRIMIDINICI DELL'ATTIVITA' FOSFODIESTERASICA PRO-METASTASI DI H-PRUNE 31
Studies on alternate strand triple helix formation by oligodeoxyribonucleotides containing a 3'-3' phosphodiester bond. 30
Affinity, stability and polarity of binding of the TATA binding protein governed by flexure at the TATA box. 30
Effect of a modified thymine on the structure and stability of [d(TGGGT)]4 quadruplex 30
The insertion of two 8-methyl-2'-deoxyguanosineresidues in tetramolecular quadruplex structures:trying to orientate the strands 30
A further contribution to the extreme variability of quadruplex structures from oligodeoxyribonucleotides containing inversion of polarity sites in the G-tract 29
Heterochiral oligodeoxynucleotides forming quadruplex structures 29
Novel pyrimidopyrimidine derivatives for inhibition of cellular proliferation and motility induced by h-prune in breast cancer 29
EFFECT OF GUANINE BASES MODIFICATIONS AND L-DNA ON STABILITY AND KINETIC OF FORMATION OF TETRAMOLECULAR QUADRUPLEXES 29
Totale 4.392
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Categoria #
all - tutte 20.282
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 20.282
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201930 0 0 0 0 0 0 0 0 0 0 12 18
2019/2020696 246 4 61 10 96 20 38 5 15 42 71 88
2020/2021909 16 62 84 65 110 119 74 20 138 12 98 111
2021/2022956 15 2 15 13 12 65 6 50 145 126 166 341
2022/20231.403 206 105 35 194 124 182 7 155 176 134 69 16
2023/2024554 26 134 92 41 40 58 27 107 12 17 0 0
Totale 5.793