IRIS
GALEONE, ALDO
 Distribuzione geografica
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Continente #
AS - Asia 6.378
NA - Nord America 5.985
EU - Europa 4.943
SA - Sud America 811
AF - Africa 163
OC - Oceania 14
AN - Antartide 1
Continente sconosciuto - Info sul continente non disponibili 1
Totale 18.296
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Nazione #
US - Stati Uniti d'America 5.764
SG - Singapore 2.862
RU - Federazione Russa 1.885
IT - Italia 1.289
CN - Cina 1.179
VN - Vietnam 1.171
BR - Brasile 666
HK - Hong Kong 489
UA - Ucraina 297
DE - Germania 296
FR - Francia 226
FI - Finlandia 218
NL - Olanda 157
GB - Regno Unito 136
IE - Irlanda 129
JP - Giappone 129
IN - India 125
CA - Canada 117
SE - Svezia 117
BD - Bangladesh 62
MX - Messico 60
ZA - Sudafrica 58
AR - Argentina 55
PL - Polonia 47
TR - Turchia 40
KR - Corea 36
IQ - Iraq 35
PH - Filippine 33
CI - Costa d'Avorio 32
ID - Indonesia 29
TH - Thailandia 29
PK - Pakistan 27
EC - Ecuador 26
ES - Italia 25
PT - Portogallo 23
CO - Colombia 16
UZ - Uzbekistan 15
BE - Belgio 14
MA - Marocco 14
PY - Paraguay 13
TW - Taiwan 13
AT - Austria 12
AU - Australia 12
CL - Cile 12
IR - Iran 12
VE - Venezuela 12
JM - Giamaica 10
KE - Kenya 10
TN - Tunisia 10
AE - Emirati Arabi Uniti 9
SA - Arabia Saudita 9
IL - Israele 8
AM - Armenia 7
CZ - Repubblica Ceca 7
DZ - Algeria 7
KZ - Kazakistan 7
MY - Malesia 7
AZ - Azerbaigian 6
JO - Giordania 6
LT - Lituania 6
PE - Perù 6
RO - Romania 6
CR - Costa Rica 5
DK - Danimarca 5
NP - Nepal 5
BY - Bielorussia 4
CH - Svizzera 4
DO - Repubblica Dominicana 4
EG - Egitto 4
ET - Etiopia 4
KH - Cambogia 4
MK - Macedonia 4
NI - Nicaragua 4
SD - Sudan 4
SK - Slovacchia (Repubblica Slovacca) 4
TT - Trinidad e Tobago 4
YE - Yemen 4
BB - Barbados 3
BG - Bulgaria 3
EE - Estonia 3
HR - Croazia 3
HU - Ungheria 3
KG - Kirghizistan 3
MD - Moldavia 3
MN - Mongolia 3
MU - Mauritius 3
OM - Oman 3
PA - Panama 3
RS - Serbia 3
SI - Slovenia 3
SN - Senegal 3
BA - Bosnia-Erzegovina 2
BH - Bahrain 2
BO - Bolivia 2
GE - Georgia 2
GR - Grecia 2
GT - Guatemala 2
HN - Honduras 2
ME - Montenegro 2
MT - Malta 2
Totale 18.258
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Città #
Singapore 1.332
San Jose 839
Chandler 637
Hong Kong 471
Moscow 450
Ashburn 414
Beijing 384
Naples 339
Jacksonville 293
Ho Chi Minh City 292
Hanoi 232
Napoli 214
Santa Clara 184
The Dalles 168
Los Angeles 162
Lauterbourg 155
Princeton 152
Millbury 140
Amsterdam 134
Boston 115
Woodbridge 114
Nanjing 112
Dong Ket 94
Tokyo 90
Hefei 85
Buffalo 78
Wilmington 70
Ann Arbor 69
Munich 67
Houston 66
New York 66
Da Nang 60
São Paulo 54
Council Bluffs 53
Haiphong 53
Orem 45
Ottawa 45
Redondo Beach 45
Seattle 39
Dallas 38
Des Moines 35
Nanchang 34
Turku 34
Hebei 33
Brooklyn 29
Frankfurt am Main 29
Warsaw 29
Helsinki 28
Milan 28
Portici 28
Rio de Janeiro 28
Shenyang 28
Denver 26
Norwalk 26
Tianjin 26
Montreal 25
Rome 25
Biên Hòa 24
Mexico City 23
Phoenix 23
Chennai 22
Chicago 22
Dearborn 22
Jiaxing 22
Falls Church 21
Toronto 21
Johannesburg 18
London 18
Poplar 18
San Francisco 18
Manchester 17
Mumbai 17
Atlanta 16
Paris 16
Baghdad 15
Changsha 15
Hangzhou 15
Lawrence 15
Stockholm 15
Ankara 14
Belo Horizonte 14
Boardman 14
Kronberg 14
Augusta 13
Bangkok 13
Can Tho 13
Formia 13
Brasília 12
Falkenstein 12
Ninh Bình 12
Pune 12
Salerno 12
Salvador 12
Tashkent 12
Washington 12
Guangzhou 11
Nuremberg 11
Poznan 11
Redwood City 11
Thái Bình 11
Totale 9.613
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Nome #
Pyrimido[5,4-d]Pyrimidine or pyrimidine derivates compounds and uses there of in the treatment of cancer 216
Ptaquiloside, the major carcinogen of bracken fern, in the pooled raw milk of healthy sheep and goats: an underestimated, global concern of food safety 183
Structural and biological properties of novel G4-aptamer-drug conjugates as a vehicle for 5-fluoro-2′-deoxyuridine 169
A bunch-oligonucleotide forming stable monomolecular quadruplex containing a T-tetrad. 163
Metastatic group 3 medulloblastoma is driven by PRUNE1 targeting NME1-TGF-β-OTX2-SNAIL via PTEN inhibition. 163
Antiproliferative Effects of the Aptamer d(GGGT) 4 and Its Analogues with an Abasic-Site Mimic Loop on Different Cancer Cells 160
The ‘‘Janus face” of the thrombin binding aptamer: Investigating the anticoagulant and antiproliferative properties through straightforward chemical modifications 151
PROBING THE EFFECTS OF CHEMICAL MODIFICATIONS ON THROMBIN BINDING APTAMER BIOLOGICAL ACTIVITY. 148
From protein-protein interaction to E2 inhibitors leads: identification of peptide binding of UbcH10 147
5-Hydroxymethyl-2′-Deoxyuridine Residues in the Thrombin Binding Aptamer: Investigating Anticoagulant Activity by Making a Tiny Chemical Modification 147
Backbone modified TBA analogues endowed with antiproliferative activity 147
1H-NMR study of the quadruplex [d(TGGGT)]4 containing a modified thymine 146
Site specific replacements of a single loop nucleoside with a dibenzyl linker may switch the activity of TBA from anticoagulant to antiproliferative 146
EFFECT OF THE INTRODUCTION OF AN A-RESIDUE INTO A QUADRUPLEX FORMING OLIGONUCLEOTIDE CONTAINING A 5'-5' POLARITY OF INVERSION SITE 143
MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines 143
A straightforward modification in the thrombin binding aptamer improving stability, affinity to thrombin and nuclease resistance 143
Synthesis, structural studies and biological properties of new TBA analogues containing an acyclic nucleotide 142
A topological classification of G-quadruplex structures 141
Quadruplex DNA: structural features and potential applications 141
Molecular Modelling Studies of Four Stranded Quadruplexes Containing a 3’-3’ or 5’-5’ Inversion of Polarity Site 140
UL3 mediated nucleolar stress pathway as a new mechanism of action of antiproliferative G-quadruplex TBA derivatives in colon cancer cells 139
Aspetti dell’interazione tra la distamicina-A e la quadruplex [d(TGGGGT)]4 138
Heterochiral oligodeoxynucleotides forming quadruplex structures 136
1H-NMR Study of the Quadruplex [d(TGGGT)]4 Containing a Modified Thymine 135
Synthesis and characterization of tetra-end linked oligonucleotides capable of forming monomolecular G-quadruplex 134
Novel pyrimidopyrimidine derivatives for inhibition of cellular proliferation and motility induced by h-prune in breast cancer 134
A NEW CLASS OF DNA QUADRUPLEX FORMED BY OLIGODEOXYRIBONUCLEOTIDES CONTAINING A 3’-3’ OR 5’-5’ INVERSION OF POLARITY SITE 132
Studio 1H-NMR dell’ interazione tra la distamicina A e la netropsina con strutture di duplex e quadruplex DNA 131
PRELIMINARY STRUCTURAL INVESTIGATIONS ON THE ANTI-HIV G-QUADRUPLEX FORMING OLIGONUCLEOTIDE TGGGAG AND ANALOGUES: EVIDENCE FOR THE PRESENCE OF AN A-TETRAD 131
Expanding the potential of G-quadruplex structures: formation of a heterochiral TBA analogue 130
Structural properties and anticoagulant/cytotoxic activities of heterochiral enantiomeric thrombin binding aptamer (TBA) derivatives 130
New G-quadruplex DNA catalysts in enantioselective sulfoxidation reaction 129
Synthesis and structural study of quadruplex structures containing 2'-deoxy-8-methyladenosine 129
G-triplex stability in human telomeric DNA with epigenetic modification/oxidative damage to thymine 129
Discovering New G-Quadruplex DNA Catalysts in Enantioselective Sulfoxidation Reaction 128
A MINI-LIBRARY OF TBA ANALOGUES CONTAINING 3'-3' AND 5'-5' INVERSION OF POLARITY SITES 127
A NEW CLASS OF DNA QUADRUPLEX FORMED BY OLIGODEOXYRIBONUCLEOTIDES CONTAINING A 3'-3' OR 5'-5' INVERSION OF POLARITY SITE 127
MiR-34a Targeting of Notch Ligand Delta-Like 1 ImpairsCD15+/CD133+ Tumor-Propagating Cells and SupportsNeural Differentiation in 126
Introduzione alla chimica organica 126
MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma. 126
G-Quadruplex aptamer T30175 and its derivatives: exploring new potential anticancer activities 125
Thrombin-Binding Aptamer (TBA) derivatives with one or two additional G-Tetrads: properties and potential antiproliferative activity 125
8-Methyl-2'-deoxyguanosine incorporation into parallel DNA quadruplex structures 125
Heterochiral oligodeoxynucleotides forming quadruplex structures 125
Exploring the binding of d(GGGT)4 to the HIV-1 integrase: An approach to investigate G-quadruplex aptamer/target protein interactions. 125
Solid phase approach to the preparation of small circular DNA and RNA fragments 124
Monomolecular G-quadruplex structures with inversion of polarity sites: new topologies and potentiality 124
Studio di strutture cruciformi mediante NMR 122
Effects of abasic sites on structural, thermodynamic and kinetic properties of quadruplex structures. 121
Chimica Organica 121
The abasic site lesions in the human telomeric sequence d[TA(G3T2A)3G3]: A thermodynamic point of view 120
Unusual Chair-Like G-Quadruplex Structures: Heterochiral TBA Analogues Containing Inversion of Polarity Sites 119
Syntheses of [1-15N]-2'-deoxyinosine, [4-15N]-2'-deoxyAICAR, and [1-15N]-2'-deoxyguanosine. 119
Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d(TGGGGT)]4 119
Physico-chemical studies of quadruple helices of modified human telomeric DNA 119
Homology building, protein-protein docking and MD approach to the simulation of the quaternary complex E1/E2/Ub2 119
NMR STUDIES ON QUADRUPLEX STRUCTURES CONTAINING ABASIC SITES 119
Effects of 8-methylguanine on structure, stability and kinetics of formation of tetramolecular quadruplexes 119
Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops 119
Probing the Effects of Chemical Modifications on Anticoagulant and Antiproliferative Activity of Thrombin Binding Aptamer 118
Structural Model of the hUbA1-UbcH10 Quaternary Complex: In Silico and Experimental Analysis of the Protein-Protein Interactions between E1, E2 and Ubiquitin 118
Thrombin binding aptamer analogues containing inversion of polarity sites endowed with antiproliferative and anti-motility properties against Calu-6 cells 118
Structural and Biological Features of G-Quadruplex Aptamers as Promising Inhibitors of the STAT3 Signaling Pathway 118
THE ABASIC SITE LESIONS IN THE HUMAN TELOMERIC SEQUENCE d[TA(G3T2A)3G3]: A THERMODYNAMIC POINT OF VIEW 117
Site-specific replacement of the thymine methyl group by fluorine in thrombin binding aptamer significantly improves structural stability and anticoagulant activity 117
Exploring New Potential Anticancer Activities of the G-Quadruplexes Formed by [(GTG2T(G3T)3] and Its Derivatives with an Abasic Site Replacing Single Thymidine 117
EFFECT OF GUANINE BASES MODIFICATIONS AND L-DNA ON STABILITY AND KINETIC OF FORMATION OF TETRAMOLECULAR QUADRUPLEXES 116
Synthesis of 5-methylamino-2'-deoxyuridine derivatives. 115
1H and 13C NMR spectra of imidazo[1,2-a]pyrazines. 114
Solid phase synthesis of cyclic oligodeoxyribonucleotides intermolecular versus intramolecular coupling. 114
Bunchy oligonucleotides forming new stable DNA quadruplex structure 114
Homology building, protein-protein docking and MD approach to the simulation of the quaternary complex E1/E2/Ub2. 112
PRELIMINARY STRUCTURAL INVESTIGATIONS ON THE ANTI-HIV G-QUADRUPLEX FORMING OLIGONUCLEOTIDE TGGGAG AND ANALOGUES: EVIDENCE FOR THE PRESENCE OF AN A-TETRAD 112
2'-Deoxy-8-(propyn-1-yl)adenosine-containing oligonucleotides: effects on stability of duplex and quadruplex structures 111
Improved thrombin binding aptamer analogues containing inversion of polarity sites: structural effects of extra-residues at the ends 109
The oxidative damage to the human telomere: effects of 5-hydroxymethyl-2'-deoxyuridine on telomeric G-quadruplex structures 108
Biophysical properties of quadruple helices of modified human telomeric DNA 108
NUOVI INIBITORI PIRIMIDO-PIRIMIDINICI DELL'ATTIVITA' FOSFODIESTERASICA PRO-METASTASI DI H-PRUNE 108
Transferrin-conjugated SNALPs encapsulating 2'-O-methylated miR-34a for the treatment of multiple myeloma. 108
Automated solid phase synthesis of cyclic oligonucleotides: a further improvement 107
A new class of DNA quadruplexes formed by oligodeoxyribonucleotides containing a 3'-3' or 5'-5' inversion of polarity site 107
Synthesis of 3'-3'-linked pyrimidine oligonucleotides containing an acridine moiety for alternate strand triple helix formation 107
The insertion of two 8-methyl-2'-deoxyguanosineresidues in tetramolecular quadruplex structures:trying to orientate the strands 107
Oligonucleotidi contenenti 2’-deossi-8-(1—propinil)-Adenosina: stabilità delle strutture quadruplex. 107
Aptamer-Drug conjugates for a targeted and synergistic anticancer Response: Exploiting T30923-5-fluoro-2′-deoxyuridine (INT-FdU) derivatives 106
GLI EFFETTI DELL’INTRODUZIONE DI SITI DI INVERSIONE DELLA POLARITA’ SULLA STRUTTURA QUADRUPLEX DEL DNA (TGGGT)4 106
Aptamers against the β-conglutin allergen: Insights into the behavior of the shortest multimeric (intra)molecular dna gquadruplex 106
Synthesis and characterization of poly(dl-lactic acid)-idoxuridine conjugate. 105
A further contribution to the extreme variability of quadruplex structures from oligodeoxyribonucleotides containing inversion of polarity sites in the G-tract 105
EFFECTS OF THE SYN/ANTI EQUILIBRIUM MODULATION ON THE STRUCTURAL PROPERTIES OF TETRAMOLECULAR QUADRUPLEXES, 105
A novel pyrimidine tetrad contributing to stabilize tetramolecular G-quadruplex structures. 105
Synthesis of triple helix forming oligonucleotides with a phenanthroline moiety into the 3’-3’ inversion site of polarity 104
PNA-DNA chimeras forming quadruplex structures 104
Synthetic polynucleotides and analogues as models for studies concerning DNA. 104
Easy chemical modifications to explore the ‘Janus face’ of TBA: anticoagulant vs antiproliferative properties. 104
Investigating the properties of TBA variants with twin thrombin binding domains 104
Properties and Potential Antiproliferative Activity of Thrombin-Binding Aptamer (TBA) Derivatives with One or Two Additional G-Tetrads 104
Binding mode of distamycin to d(CGTACGTACG)2 in the 2:1 solution complex as determined by two-dimensional 1H NMR and molecular modeling studies 103
Sintesi di oligonucleotidi contenenti una unità di fenantrolina nel sito di inversione della polarità 3’-3’. 103
STUDIES ON HETEROCHIRAL OLIGONUCLEOTIDES FORMING QUADRUPLEX STRUCTURES 103
Totale 12.483
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Categoria #
all - tutte 58.789
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 58.789
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021111 0 0 0 0 0 0 0 0 0 0 0 111
2021/2022956 15 2 15 13 12 65 6 50 145 126 166 341
2022/20231.403 206 105 35 194 124 182 7 155 176 134 69 16
2023/2024753 26 134 92 41 40 58 27 107 12 17 143 56
2024/20254.255 223 265 13 25 160 169 517 247 333 417 1.533 353
2025/20268.497 893 661 885 783 1.559 283 868 587 1.086 575 245 72
Totale 18.744