IRIS
GALEONE, ALDO
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
AS - Asia 6.460
NA - Nord America 6.269
EU - Europa 5.018
SA - Sud America 828
Continente sconosciuto - Info sul continente non disponibili 449
AF - Africa 165
OC - Oceania 14
AN - Antartide 1
Totale 19.204
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 6.019
SG - Singapore 2.866
RU - Federazione Russa 1.885
IT - Italia 1.349
CN - Cina 1.187
VN - Vietnam 1.172
BR - Brasile 673
HK - Hong Kong 491
UA - Ucraina 300
DE - Germania 296
FR - Francia 226
FI - Finlandia 218
NL - Olanda 159
GB - Regno Unito 140
IE - Irlanda 129
JP - Giappone 129
CA - Canada 127
IN - India 125
BD - Bangladesh 121
SE - Svezia 117
MX - Messico 62
ZA - Sudafrica 58
AR - Argentina 56
PL - Polonia 48
TR - Turchia 40
KR - Corea 36
IQ - Iraq 35
PH - Filippine 34
CI - Costa d'Avorio 32
ID - Indonesia 31
EC - Ecuador 29
TH - Thailandia 29
ES - Italia 27
PK - Pakistan 27
PT - Portogallo 23
CO - Colombia 21
UZ - Uzbekistan 15
BE - Belgio 14
MA - Marocco 14
PY - Paraguay 13
TW - Taiwan 13
VE - Venezuela 13
AT - Austria 12
AU - Australia 12
CL - Cile 12
IR - Iran 12
SA - Arabia Saudita 11
JM - Giamaica 10
KE - Kenya 10
TN - Tunisia 10
AE - Emirati Arabi Uniti 9
CR - Costa Rica 9
MY - Malesia 9
GT - Guatemala 8
IL - Israele 8
AM - Armenia 7
CZ - Repubblica Ceca 7
DZ - Algeria 7
KZ - Kazakistan 7
RO - Romania 7
AZ - Azerbaigian 6
BB - Barbados 6
JO - Giordania 6
LT - Lituania 6
PE - Perù 6
DK - Danimarca 5
NI - Nicaragua 5
NP - Nepal 5
BY - Bielorussia 4
CH - Svizzera 4
DO - Repubblica Dominicana 4
EG - Egitto 4
ET - Etiopia 4
KH - Cambogia 4
MK - Macedonia 4
RS - Serbia 4
SD - Sudan 4
SK - Slovacchia (Repubblica Slovacca) 4
TT - Trinidad e Tobago 4
YE - Yemen 4
BG - Bulgaria 3
EE - Estonia 3
GE - Georgia 3
GR - Grecia 3
HR - Croazia 3
HU - Ungheria 3
KG - Kirghizistan 3
MD - Moldavia 3
MN - Mongolia 3
MU - Mauritius 3
OM - Oman 3
PA - Panama 3
PR - Porto Rico 3
SC - Seychelles 3
SI - Slovenia 3
SN - Senegal 3
BA - Bosnia-Erzegovina 2
BH - Bahrain 2
BO - Bolivia 2
GP - Guadalupe 2
Totale 18.715
Salva come PNG Salva come JPEG
Città #
Singapore 1.335
San Jose 858
Chandler 638
Hong Kong 472
Moscow 450
Ashburn 443
Beijing 384
Naples 357
Jacksonville 294
Ho Chi Minh City 293
Hanoi 232
Napoli 214
Santa Clara 203
Los Angeles 181
The Dalles 169
Lauterbourg 155
Princeton 152
Millbury 140
Amsterdam 134
Boston 115
Woodbridge 114
Nanjing 112
Dong Ket 94
Tokyo 90
Buffalo 89
Hefei 85
New York 81
Council Bluffs 73
Wilmington 70
Ann Arbor 69
Houston 67
Munich 67
Da Nang 60
São Paulo 56
Haiphong 53
Dallas 47
Orem 46
Ottawa 46
Redondo Beach 45
Seattle 40
Des Moines 36
Milan 34
Nanchang 34
Turku 34
Hebei 33
Brooklyn 30
Frankfurt am Main 29
Warsaw 29
Helsinki 28
Portici 28
Rio de Janeiro 28
Shenyang 28
Denver 26
Montreal 26
Norwalk 26
Rome 26
Tianjin 26
Biên Hòa 24
Chicago 24
Phoenix 24
Mexico City 23
Toronto 23
Chennai 22
Dearborn 22
Jiaxing 22
Falls Church 21
Atlanta 20
London 19
Johannesburg 18
Poplar 18
San Francisco 18
Manchester 17
Mumbai 17
Paris 16
Baghdad 15
Changsha 15
Hangzhou 15
Lawrence 15
Stockholm 15
Washington 15
Ankara 14
Belo Horizonte 14
Boardman 14
Kronberg 14
Augusta 13
Bangkok 13
Can Tho 13
Formia 13
Salerno 13
Brasília 12
Falkenstein 12
Ninh Bình 12
Pune 12
Salvador 12
Tashkent 12
Charlotte 11
Guangzhou 11
Nuremberg 11
Poznan 11
Redwood City 11
Totale 9.810
Salva come PNG Salva come JPEG
Nome #
Pyrimido[5,4-d]Pyrimidine or pyrimidine derivates compounds and uses there of in the treatment of cancer 218
Ptaquiloside, the major carcinogen of bracken fern, in the pooled raw milk of healthy sheep and goats: an underestimated, global concern of food safety 194
Structural and biological properties of novel G4-aptamer-drug conjugates as a vehicle for 5-fluoro-2′-deoxyuridine 174
Metastatic group 3 medulloblastoma is driven by PRUNE1 targeting NME1-TGF-β-OTX2-SNAIL via PTEN inhibition. 165
A bunch-oligonucleotide forming stable monomolecular quadruplex containing a T-tetrad. 164
Properties and Potential Antiproliferative Activity of Thrombin-Binding Aptamer (TBA) Derivatives with One or Two Additional G-Tetrads 161
Antiproliferative Effects of the Aptamer d(GGGT) 4 and Its Analogues with an Abasic-Site Mimic Loop on Different Cancer Cells 160
PROBING THE EFFECTS OF CHEMICAL MODIFICATIONS ON THROMBIN BINDING APTAMER BIOLOGICAL ACTIVITY. 154
The ‘‘Janus face” of the thrombin binding aptamer: Investigating the anticoagulant and antiproliferative properties through straightforward chemical modifications 152
From protein-protein interaction to E2 inhibitors leads: identification of peptide binding of UbcH10 150
Quadruplex DNA: structural features and potential applications 149
Backbone modified TBA analogues endowed with antiproliferative activity 149
New G-quadruplex DNA catalysts in enantioselective sulfoxidation reaction 148
1H-NMR study of the quadruplex [d(TGGGT)]4 containing a modified thymine 148
5-Hydroxymethyl-2′-Deoxyuridine Residues in the Thrombin Binding Aptamer: Investigating Anticoagulant Activity by Making a Tiny Chemical Modification 147
Site specific replacements of a single loop nucleoside with a dibenzyl linker may switch the activity of TBA from anticoagulant to antiproliferative 147
Synthesis, structural studies and biological properties of new TBA analogues containing an acyclic nucleotide 145
MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines 144
A straightforward modification in the thrombin binding aptamer improving stability, affinity to thrombin and nuclease resistance 144
EFFECT OF THE INTRODUCTION OF AN A-RESIDUE INTO A QUADRUPLEX FORMING OLIGONUCLEOTIDE CONTAINING A 5'-5' POLARITY OF INVERSION SITE 143
Structural Model of the hUbA1-UbcH10 Quaternary Complex: In Silico and Experimental Analysis of the Protein-Protein Interactions between E1, E2 and Ubiquitin 143
A topological classification of G-quadruplex structures 141
Molecular Modelling Studies of Four Stranded Quadruplexes Containing a 3’-3’ or 5’-5’ Inversion of Polarity Site 141
UL3 mediated nucleolar stress pathway as a new mechanism of action of antiproliferative G-quadruplex TBA derivatives in colon cancer cells 141
Synthesis and characterization of tetra-end linked oligonucleotides capable of forming monomolecular G-quadruplex 139
Aspetti dell’interazione tra la distamicina-A e la quadruplex [d(TGGGGT)]4 139
Novel pyrimidopyrimidine derivatives for inhibition of cellular proliferation and motility induced by h-prune in breast cancer 137
Heterochiral oligodeoxynucleotides forming quadruplex structures 137
Thrombin-Binding Aptamer (TBA) derivatives with one or two additional G-Tetrads: properties and potential antiproliferative activity 135
1H-NMR Study of the Quadruplex [d(TGGGT)]4 Containing a Modified Thymine 135
A NEW CLASS OF DNA QUADRUPLEX FORMED BY OLIGODEOXYRIBONUCLEOTIDES CONTAINING A 3’-3’ OR 5’-5’ INVERSION OF POLARITY SITE 134
Synthesis and structural study of quadruplex structures containing 2'-deoxy-8-methyladenosine 132
Expanding the potential of G-quadruplex structures: formation of a heterochiral TBA analogue 132
Structural properties and anticoagulant/cytotoxic activities of heterochiral enantiomeric thrombin binding aptamer (TBA) derivatives 132
8-Methyl-2'-deoxyguanosine incorporation into parallel DNA quadruplex structures 131
Studio 1H-NMR dell’ interazione tra la distamicina A e la netropsina con strutture di duplex e quadruplex DNA 131
PRELIMINARY STRUCTURAL INVESTIGATIONS ON THE ANTI-HIV G-QUADRUPLEX FORMING OLIGONUCLEOTIDE TGGGAG AND ANALOGUES: EVIDENCE FOR THE PRESENCE OF AN A-TETRAD 131
A MINI-LIBRARY OF TBA ANALOGUES CONTAINING 3'-3' AND 5'-5' INVERSION OF POLARITY SITES 129
G-triplex stability in human telomeric DNA with epigenetic modification/oxidative damage to thymine 129
Discovering New G-Quadruplex DNA Catalysts in Enantioselective Sulfoxidation Reaction 129
Monomolecular G-quadruplex structures with inversion of polarity sites: new topologies and potentiality 128
G-Quadruplex aptamer T30175 and its derivatives: exploring new potential anticancer activities 127
Introduzione alla chimica organica 127
MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma. 127
A NEW CLASS OF DNA QUADRUPLEX FORMED BY OLIGODEOXYRIBONUCLEOTIDES CONTAINING A 3'-3' OR 5'-5' INVERSION OF POLARITY SITE 127
Exploring the binding of d(GGGT)4 to the HIV-1 integrase: An approach to investigate G-quadruplex aptamer/target protein interactions. 127
MiR-34a Targeting of Notch Ligand Delta-Like 1 ImpairsCD15+/CD133+ Tumor-Propagating Cells and SupportsNeural Differentiation in 126
Heterochiral oligodeoxynucleotides forming quadruplex structures 125
Solid phase approach to the preparation of small circular DNA and RNA fragments 124
Probing the Effects of Chemical Modifications on Anticoagulant and Antiproliferative Activity of Thrombin Binding Aptamer 123
Unusual Chair-Like G-Quadruplex Structures: Heterochiral TBA Analogues Containing Inversion of Polarity Sites 123
Effects of abasic sites on structural, thermodynamic and kinetic properties of quadruplex structures. 123
Studio di strutture cruciformi mediante NMR 123
Syntheses of [1-15N]-2'-deoxyinosine, [4-15N]-2'-deoxyAICAR, and [1-15N]-2'-deoxyguanosine. 122
Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d(TGGGGT)]4 122
Physico-chemical studies of quadruple helices of modified human telomeric DNA 121
The abasic site lesions in the human telomeric sequence d[TA(G3T2A)3G3]: A thermodynamic point of view 121
Chimica Organica 121
Effects of 8-methylguanine on structure, stability and kinetics of formation of tetramolecular quadruplexes 121
Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops 121
Homology building, protein-protein docking and MD approach to the simulation of the quaternary complex E1/E2/Ub2 120
Thrombin binding aptamer analogues containing inversion of polarity sites endowed with antiproliferative and anti-motility properties against Calu-6 cells 120
NMR STUDIES ON QUADRUPLEX STRUCTURES CONTAINING ABASIC SITES 119
Structural and Biological Features of G-Quadruplex Aptamers as Promising Inhibitors of the STAT3 Signaling Pathway 119
EFFECT OF GUANINE BASES MODIFICATIONS AND L-DNA ON STABILITY AND KINETIC OF FORMATION OF TETRAMOLECULAR QUADRUPLEXES 117
THE ABASIC SITE LESIONS IN THE HUMAN TELOMERIC SEQUENCE d[TA(G3T2A)3G3]: A THERMODYNAMIC POINT OF VIEW 117
Site-specific replacement of the thymine methyl group by fluorine in thrombin binding aptamer significantly improves structural stability and anticoagulant activity 117
Exploring New Potential Anticancer Activities of the G-Quadruplexes Formed by [(GTG2T(G3T)3] and Its Derivatives with an Abasic Site Replacing Single Thymidine 117
2'-Deoxy-8-(propyn-1-yl)adenosine-containing oligonucleotides: effects on stability of duplex and quadruplex structures 116
Synthesis of 5-methylamino-2'-deoxyuridine derivatives. 115
1H and 13C NMR spectra of imidazo[1,2-a]pyrazines. 115
Solid phase synthesis of cyclic oligodeoxyribonucleotides intermolecular versus intramolecular coupling. 115
Bunchy oligonucleotides forming new stable DNA quadruplex structure 115
Homology building, protein-protein docking and MD approach to the simulation of the quaternary complex E1/E2/Ub2. 115
Biophysical properties of quadruple helices of modified human telomeric DNA 113
PRELIMINARY STRUCTURAL INVESTIGATIONS ON THE ANTI-HIV G-QUADRUPLEX FORMING OLIGONUCLEOTIDE TGGGAG AND ANALOGUES: EVIDENCE FOR THE PRESENCE OF AN A-TETRAD 113
The oxidative damage to the human telomere: effects of 5-hydroxymethyl-2'-deoxyuridine on telomeric G-quadruplex structures 111
Oligonucleotidi contenenti 2’-deossi-8-(1—propinil)-Adenosina: stabilità delle strutture quadruplex. 110
Improved thrombin binding aptamer analogues containing inversion of polarity sites: structural effects of extra-residues at the ends 110
Aptamers against the β-conglutin allergen: Insights into the behavior of the shortest multimeric (intra)molecular dna gquadruplex 110
A new class of DNA quadruplexes formed by oligodeoxyribonucleotides containing a 3'-3' or 5'-5' inversion of polarity site 109
Synthesis of 3'-3'-linked pyrimidine oligonucleotides containing an acridine moiety for alternate strand triple helix formation 109
NUOVI INIBITORI PIRIMIDO-PIRIMIDINICI DELL'ATTIVITA' FOSFODIESTERASICA PRO-METASTASI DI H-PRUNE 109
Transferrin-conjugated SNALPs encapsulating 2'-O-methylated miR-34a for the treatment of multiple myeloma. 109
Aptamer-Drug conjugates for a targeted and synergistic anticancer Response: Exploiting T30923-5-fluoro-2′-deoxyuridine (INT-FdU) derivatives 108
Circular dichroism and termal melting differentiation of Hoechst 33258 bindings to the curved (A4T4) and non curved (T4A4) DNA sequences. 108
Synthesis of triple helix forming oligonucleotides with a phenanthroline moiety into the 3’-3’ inversion site of polarity 108
PNA-DNA chimeras forming quadruplex structures 108
A novel pyrimidine tetrad contributing to stabilize tetramolecular G-quadruplex structures. 108
Synthesis and characterization of poly(dl-lactic acid)-idoxuridine conjugate. 107
Automated solid phase synthesis of cyclic oligonucleotides: a further improvement 107
Design, synthesis, biophysical and biological studies on trisubstituted naphthalimides as G-Quadruplex ligands 107
The insertion of two 8-methyl-2'-deoxyguanosineresidues in tetramolecular quadruplex structures:trying to orientate the strands 107
Easy chemical modifications to explore the ‘Janus face’ of TBA: anticoagulant vs antiproliferative properties. 107
Structural study of four-stranded quadruplex structures containing 2'-deoxy-8-(propyn-1-yl)adenosine 106
A further contribution to the extreme variability of quadruplex structures from oligodeoxyribonucleotides containing inversion of polarity sites in the G-tract 106
EFFECTS OF THE SYN/ANTI EQUILIBRIUM MODULATION ON THE STRUCTURAL PROPERTIES OF TETRAMOLECULAR QUADRUPLEXES, 106
GLI EFFETTI DELL’INTRODUZIONE DI SITI DI INVERSIONE DELLA POLARITA’ SULLA STRUTTURA QUADRUPLEX DEL DNA (TGGGT)4 106
Improving the Biological Properties of Thrombin-Binding Aptamer by Incorporation of 8-Bromo-2′-Deoxyguanosine and 2′-Substituted RNA Analogues 105
Binding mode of distamycin to d(CGTACGTACG)2 in the 2:1 solution complex as determined by two-dimensional 1H NMR and molecular modeling studies 105
Totale 12.782
Salva come PNG Salva come JPEG
Categoria #
all - tutte 63.455
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 63.455
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022941 0 2 15 13 12 65 6 50 145 126 166 341
2022/20231.403 206 105 35 194 124 182 7 155 176 134 69 16
2023/2024753 26 134 92 41 40 58 27 107 12 17 143 56
2024/20254.255 223 265 13 25 160 169 517 247 333 417 1.533 353
2025/20268.714 893 661 885 783 1.559 283 868 587 1.086 575 245 289
2026/2027243 190 53 0 0 0 0 0 0 0 0 0 0
Totale 19.204