IRIS
GALEONE, ALDO
 Distribuzione geografica
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Continente #
AS - Asia 4.856
EU - Europa 4.466
NA - Nord America 4.354
SA - Sud America 754
AF - Africa 130
OC - Oceania 13
AN - Antartide 1
Continente sconosciuto - Info sul continente non disponibili 1
Totale 14.575
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Nazione #
US - Stati Uniti d'America 4.181
SG - Singapore 2.672
RU - Federazione Russa 1.858
IT - Italia 1.125
CN - Cina 1.017
BR - Brasile 627
HK - Hong Kong 439
VN - Vietnam 375
UA - Ucraina 294
DE - Germania 269
FI - Finlandia 210
NL - Olanda 144
IE - Irlanda 125
GB - Regno Unito 123
SE - Svezia 117
CA - Canada 92
IN - India 79
MX - Messico 51
ZA - Sudafrica 50
AR - Argentina 47
JP - Giappone 42
PL - Polonia 40
TR - Turchia 39
FR - Francia 36
BD - Bangladesh 32
CI - Costa d'Avorio 32
ID - Indonesia 28
EC - Ecuador 22
ES - Italia 22
PT - Portogallo 22
IQ - Iraq 17
CO - Colombia 16
PK - Pakistan 13
AT - Austria 12
IR - Iran 12
AU - Australia 11
BE - Belgio 11
KR - Corea 11
PY - Paraguay 11
VE - Venezuela 11
CL - Cile 10
UZ - Uzbekistan 9
MA - Marocco 8
AM - Armenia 7
CZ - Repubblica Ceca 7
IL - Israele 7
AE - Emirati Arabi Uniti 6
AZ - Azerbaigian 6
KZ - Kazakistan 6
PE - Perù 6
TW - Taiwan 6
DK - Danimarca 5
KE - Kenya 5
MY - Malesia 5
RO - Romania 5
CR - Costa Rica 4
DZ - Algeria 4
JM - Giamaica 4
LT - Lituania 4
PH - Filippine 4
SD - Sudan 4
SK - Slovacchia (Repubblica Slovacca) 4
TN - Tunisia 4
TT - Trinidad e Tobago 4
YE - Yemen 4
BG - Bulgaria 3
BY - Bielorussia 3
CH - Svizzera 3
EE - Estonia 3
ET - Etiopia 3
HU - Ungheria 3
KG - Kirghizistan 3
KH - Cambogia 3
MK - Macedonia 3
PA - Panama 3
SA - Arabia Saudita 3
SN - Senegal 3
BA - Bosnia-Erzegovina 2
DO - Repubblica Dominicana 2
EG - Egitto 2
GT - Guatemala 2
HN - Honduras 2
MD - Moldavia 2
ME - Montenegro 2
MN - Mongolia 2
MU - Mauritius 2
PR - Porto Rico 2
PS - Palestinian Territory 2
RS - Serbia 2
SI - Slovenia 2
UY - Uruguay 2
VC - Saint Vincent e Grenadine 2
AF - Afghanistan, Repubblica islamica di 1
AL - Albania 1
AO - Angola 1
AQ - Antartide 1
BB - Barbados 1
BF - Burkina Faso 1
BO - Bolivia 1
CD - Congo 1
Totale 14.547
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Città #
Singapore 1.204
Chandler 621
Moscow 446
Hong Kong 438
Beijing 358
Ashburn 301
Jacksonville 289
Naples 259
Napoli 213
Santa Clara 170
Princeton 150
Los Angeles 139
Millbury 136
Amsterdam 129
Boston 115
Woodbridge 113
Nanjing 110
Dong Ket 94
Ho Chi Minh City 90
Hefei 85
Buffalo 74
Ann Arbor 69
Wilmington 69
Munich 65
Houston 63
Hanoi 55
São Paulo 50
New York 48
Ottawa 45
Redondo Beach 45
The Dalles 38
Seattle 37
Des Moines 35
Nanchang 34
Turku 33
Hebei 32
Shenyang 27
Norwalk 26
Rio de Janeiro 26
Tianjin 26
Warsaw 26
Brooklyn 25
Portici 25
Helsinki 23
Dearborn 22
Jiaxing 22
Mexico City 22
Orem 22
Falls Church 21
Dallas 20
Chennai 18
Denver 18
Montreal 18
Phoenix 18
Poplar 18
Rome 18
London 17
Milan 17
Chicago 16
Haiphong 16
Johannesburg 16
Hangzhou 15
Stockholm 15
Tokyo 15
Toronto 15
Ankara 14
Boardman 14
Da Nang 14
Kronberg 14
Lawrence 14
Manchester 14
Belo Horizonte 13
Changsha 13
Formia 13
San Francisco 13
Augusta 12
Biên Hòa 12
Brasília 12
Falkenstein 12
Paris 12
Salvador 12
Washington 12
Atlanta 11
Redwood City 11
Marano Di Napoli 10
Nuremberg 10
Caserta 9
Curitiba 9
Frankfurt am Main 9
Guangzhou 9
Lappeenranta 9
Manaus 9
Mumbai 9
Orange 9
Poznan 9
Salerno 9
Vienna 9
Brisbane 8
Cape Town 8
Charlotte 8
Totale 7.220
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Nome #
Pyrimido[5,4-d]Pyrimidine or pyrimidine derivates compounds and uses there of in the treatment of cancer 175
Ptaquiloside, the major carcinogen of bracken fern, in the pooled raw milk of healthy sheep and goats: an underestimated, global concern of food safety 143
Structural and biological properties of novel G4-aptamer-drug conjugates as a vehicle for 5-fluoro-2′-deoxyuridine 135
Metastatic group 3 medulloblastoma is driven by PRUNE1 targeting NME1-TGF-β-OTX2-SNAIL via PTEN inhibition. 134
Antiproliferative Effects of the Aptamer d(GGGT) 4 and Its Analogues with an Abasic-Site Mimic Loop on Different Cancer Cells 132
The ‘‘Janus face” of the thrombin binding aptamer: Investigating the anticoagulant and antiproliferative properties through straightforward chemical modifications 132
EFFECT OF THE INTRODUCTION OF AN A-RESIDUE INTO A QUADRUPLEX FORMING OLIGONUCLEOTIDE CONTAINING A 5'-5' POLARITY OF INVERSION SITE 129
5-Hydroxymethyl-2′-Deoxyuridine Residues in the Thrombin Binding Aptamer: Investigating Anticoagulant Activity by Making a Tiny Chemical Modification 128
1H-NMR study of the quadruplex [d(TGGGT)]4 containing a modified thymine 127
A bunch-oligonucleotide forming stable monomolecular quadruplex containing a T-tetrad. 127
A topological classification of G-quadruplex structures 122
MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines 121
Backbone modified TBA analogues endowed with antiproliferative activity 121
A straightforward modification in the thrombin binding aptamer improving stability, affinity to thrombin and nuclease resistance 119
Synthesis and characterization of tetra-end linked oligonucleotides capable of forming monomolecular G-quadruplex 118
Site specific replacements of a single loop nucleoside with a dibenzyl linker may switch the activity of TBA from anticoagulant to antiproliferative 118
UL3 mediated nucleolar stress pathway as a new mechanism of action of antiproliferative G-quadruplex TBA derivatives in colon cancer cells 118
1H-NMR Study of the Quadruplex [d(TGGGT)]4 Containing a Modified Thymine 117
Quadruplex DNA: structural features and potential applications 116
Synthesis, structural studies and biological properties of new TBA analogues containing an acyclic nucleotide 115
From protein-protein interaction to E2 inhibitors leads: identification of peptide binding of UbcH10 115
8-Methyl-2'-deoxyguanosine incorporation into parallel DNA quadruplex structures 113
Introduzione alla chimica organica 113
Molecular Modelling Studies of Four Stranded Quadruplexes Containing a 3’-3’ or 5’-5’ Inversion of Polarity Site 112
G-triplex stability in human telomeric DNA with epigenetic modification/oxidative damage to thymine 112
Monomolecular G-quadruplex structures with inversion of polarity sites: new topologies and potentiality 111
Discovering New G-Quadruplex DNA Catalysts in Enantioselective Sulfoxidation Reaction 111
Studio 1H-NMR dell’ interazione tra la distamicina A e la netropsina con strutture di duplex e quadruplex DNA 110
Expanding the potential of G-quadruplex structures: formation of a heterochiral TBA analogue 110
Unusual Chair-Like G-Quadruplex Structures: Heterochiral TBA Analogues Containing Inversion of Polarity Sites 107
G-Quadruplex aptamer T30175 and its derivatives: exploring new potential anticancer activities 106
A MINI-LIBRARY OF TBA ANALOGUES CONTAINING 3'-3' AND 5'-5' INVERSION OF POLARITY SITES 106
Aspetti dell’interazione tra la distamicina-A e la quadruplex [d(TGGGGT)]4 106
Novel pyrimidopyrimidine derivatives for inhibition of cellular proliferation and motility induced by h-prune in breast cancer 106
Exploring the binding of d(GGGT)4 to the HIV-1 integrase: An approach to investigate G-quadruplex aptamer/target protein interactions. 106
A NEW CLASS OF DNA QUADRUPLEX FORMED BY OLIGODEOXYRIBONUCLEOTIDES CONTAINING A 3’-3’ OR 5’-5’ INVERSION OF POLARITY SITE 105
Structural properties and anticoagulant/cytotoxic activities of heterochiral enantiomeric thrombin binding aptamer (TBA) derivatives 105
PROBING THE EFFECTS OF CHEMICAL MODIFICATIONS ON THROMBIN BINDING APTAMER BIOLOGICAL ACTIVITY. 105
MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma. 104
Thrombin binding aptamer analogues containing inversion of polarity sites endowed with antiproliferative and anti-motility properties against Calu-6 cells 104
New G-quadruplex DNA catalysts in enantioselective sulfoxidation reaction 103
Exploring New Potential Anticancer Activities of the G-Quadruplexes Formed by [(GTG2T(G3T)3] and Its Derivatives with an Abasic Site Replacing Single Thymidine 103
Synthesis of 5-methylamino-2'-deoxyuridine derivatives. 102
Structural Model of the hUbA1-UbcH10 Quaternary Complex: In Silico and Experimental Analysis of the Protein-Protein Interactions between E1, E2 and Ubiquitin 101
Effects of 8-methylguanine on structure, stability and kinetics of formation of tetramolecular quadruplexes 101
Synthesis and structural study of quadruplex structures containing 2'-deoxy-8-methyladenosine 100
A new class of DNA quadruplexes formed by oligodeoxyribonucleotides containing a 3'-3' or 5'-5' inversion of polarity site 99
MiR-34a Targeting of Notch Ligand Delta-Like 1 ImpairsCD15+/CD133+ Tumor-Propagating Cells and SupportsNeural Differentiation in 99
Site-specific replacement of the thymine methyl group by fluorine in thrombin binding aptamer significantly improves structural stability and anticoagulant activity 99
Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d(TGGGGT)]4 98
Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops 98
Solid phase approach to the preparation of small circular DNA and RNA fragments 97
2'-Deoxy-8-(propyn-1-yl)adenosine-containing oligonucleotides: effects on stability of duplex and quadruplex structures 97
PRELIMINARY STRUCTURAL INVESTIGATIONS ON THE ANTI-HIV G-QUADRUPLEX FORMING OLIGONUCLEOTIDE TGGGAG AND ANALOGUES: EVIDENCE FOR THE PRESENCE OF AN A-TETRAD 97
Solid phase synthesis of cyclic oligodeoxyribonucleotides intermolecular versus intramolecular coupling. 96
1H and 13C NMR spectra of imidazo[1,2-a]pyrazines. 95
Physico-chemical studies of quadruple helices of modified human telomeric DNA 94
Studio di strutture cruciformi mediante NMR 94
Chimica Organica 94
A NEW CLASS OF DNA QUADRUPLEX FORMED BY OLIGODEOXYRIBONUCLEOTIDES CONTAINING A 3'-3' OR 5'-5' INVERSION OF POLARITY SITE 94
Heterochiral oligodeoxynucleotides forming quadruplex structures 94
Transferrin-conjugated SNALPs encapsulating 2'-O-methylated miR-34a for the treatment of multiple myeloma. 94
Automated solid phase synthesis of cyclic oligonucleotides: a further improvement 93
Homology building, protein-protein docking and MD approach to the simulation of the quaternary complex E1/E2/Ub2 93
Oligonucleotidi contenenti 2’-deossi-8-(1—propinil)-Adenosina: stabilità delle strutture quadruplex. 93
Biophysical properties of quadruple helices of modified human telomeric DNA 92
EFFECT OF GUANINE BASES MODIFICATIONS AND L-DNA ON STABILITY AND KINETIC OF FORMATION OF TETRAMOLECULAR QUADRUPLEXES 92
NUOVI INIBITORI PIRIMIDO-PIRIMIDINICI DELL'ATTIVITA' FOSFODIESTERASICA PRO-METASTASI DI H-PRUNE 92
Syntheses of [1-15N]-2'-deoxyinosine, [4-15N]-2'-deoxyAICAR, and [1-15N]-2'-deoxyguanosine. 91
Effects of abasic sites on structural, thermodynamic and kinetic properties of quadruplex structures. 91
Probing the Effects of Chemical Modifications on Anticoagulant and Antiproliferative Activity of Thrombin Binding Aptamer 90
Synthesis of 3'-3'-linked pyrimidine oligonucleotides containing an acridine moiety for alternate strand triple helix formation 90
THE ABASIC SITE LESIONS IN THE HUMAN TELOMERIC SEQUENCE d[TA(G3T2A)3G3]: A THERMODYNAMIC POINT OF VIEW 90
The insertion of two 8-methyl-2'-deoxyguanosineresidues in tetramolecular quadruplex structures:trying to orientate the strands 89
NMR STUDIES ON QUADRUPLEX STRUCTURES CONTAINING ABASIC SITES 89
Structural and Biological Features of G-Quadruplex Aptamers as Promising Inhibitors of the STAT3 Signaling Pathway 89
Heterochiral oligodeoxynucleotides forming quadruplex structures 88
Aptamers against the β-conglutin allergen: Insights into the behavior of the shortest multimeric (intra)molecular dna gquadruplex 88
Synthesis and characterization of poly(dl-lactic acid)-idoxuridine conjugate. 87
Synthesis of triple helix forming oligonucleotides with a phenanthroline moiety into the 3’-3’ inversion site of polarity 87
Effects of 8-Methyl-2'-deoxyadenosine incorporation into quadruplex forming oligonucleotides 87
PRELIMINARY STRUCTURAL INVESTIGATIONS ON THE ANTI-HIV G-QUADRUPLEX FORMING OLIGONUCLEOTIDE TGGGAG AND ANALOGUES: EVIDENCE FOR THE PRESENCE OF AN A-TETRAD 87
Properties and Potential Antiproliferative Activity of Thrombin-Binding Aptamer (TBA) Derivatives with One or Two Additional G-Tetrads 87
The oxidative damage to the human telomere: effects of 5-hydroxymethyl-2'-deoxyuridine on telomeric G-quadruplex structures 86
Sintesi di oligonucleotidi contenenti una unità di fenantrolina nel sito di inversione della polarità 3’-3’. 86
Bunchy oligonucleotides forming new stable DNA quadruplex structure 86
Improved thrombin binding aptamer analogues containing inversion of polarity sites: structural effects of extra-residues at the ends 86
Improving the Biological Properties of Thrombin-Binding Aptamer by Incorporation of 8-Bromo-2′-Deoxyguanosine and 2′-Substituted RNA Analogues 85
Circular dichroism and termal melting differentiation of Hoechst 33258 bindings to the curved (A4T4) and non curved (T4A4) DNA sequences. 84
A further contribution to the extreme variability of quadruplex structures from oligodeoxyribonucleotides containing inversion of polarity sites in the G-tract 84
EFFECTS OF THE SYN/ANTI EQUILIBRIUM MODULATION ON THE STRUCTURAL PROPERTIES OF TETRAMOLECULAR QUADRUPLEXES, 84
Homology building, protein-protein docking and MD approach to the simulation of the quaternary complex E1/E2/Ub2. 84
Unprecedented right- and left-handed quadruplex structures formed by heterochiral oligodeoxyribonucleotides 84
Investigating the properties of TBA variants with twin thrombin binding domains 84
Unusual Monomolecular DNA Quadruplex Structures Using Bunch-Oligonucleotides 83
A novel pyrimidine tetrad contributing to stabilize tetramolecular G-quadruplex structures. 83
Aptamer-Drug conjugates for a targeted and synergistic anticancer Response: Exploiting T30923-5-fluoro-2′-deoxyuridine (INT-FdU) derivatives 82
Structural study of four-stranded quadruplex structures containing 2'-deoxy-8-(propyn-1-yl)adenosine 82
Design, synthesis, biophysical and biological studies on trisubstituted naphthalimides as G-Quadruplex ligands 82
Synthetic polynucleotides and analogues as models for studies concerning DNA. 82
Totale 10.175
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Categoria #
all - tutte 49.308
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 49.308
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021569 0 0 0 0 0 117 74 20 138 11 98 111
2021/2022945 15 2 15 13 12 64 6 50 143 125 163 337
2022/20231.372 204 103 34 189 120 179 7 150 172 132 67 15
2023/2024743 25 132 92 41 38 54 27 107 12 17 142 56
2024/20254.210 220 265 13 25 156 167 512 244 331 414 1.513 350
2025/20264.881 882 655 872 777 1.543 152 0 0 0 0 0 0
Totale 15.009