Preliminary NMR studies on structure formed by sequence 3'-TGA-5'-5'-GGT-3' are described. We proposed the formation of a tetramol. quadruplex in which strands are equiv. to each other and three G-tetrads are present. The possibility of the occurrence of an A-tetrad also is discussed.

EFFECT OF THE INTRODUCTION OF AN A-RESIDUE INTO A QUADRUPLEX FORMING OLIGONUCLEOTIDE CONTAINING A 5'-5' POLARITY OF INVERSION SITE

GALEONE, ALDO;MAYOL, LUCIANO;OLIVIERO, GIORGIA;RANDAZZO, ANTONIO;VIRGILIO, ANTONELLA;VIRNO, ADA
2007

Abstract

Preliminary NMR studies on structure formed by sequence 3'-TGA-5'-5'-GGT-3' are described. We proposed the formation of a tetramol. quadruplex in which strands are equiv. to each other and three G-tetrads are present. The possibility of the occurrence of an A-tetrad also is discussed.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11588/104963
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