IRIS
SEVERINO, BEATRICE
 Distribuzione geografica
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Continente #
EU - Europa 4.327
AS - Asia 3.384
NA - Nord America 3.227
SA - Sud America 490
AF - Africa 123
OC - Oceania 3
Continente sconosciuto - Info sul continente non disponibili 2
Totale 11.556
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Nazione #
US - Stati Uniti d'America 3.121
RU - Federazione Russa 1.776
SG - Singapore 1.771
IT - Italia 1.109
CN - Cina 915
DE - Germania 450
BR - Brasile 400
HK - Hong Kong 320
FR - Francia 172
FI - Finlandia 166
NL - Olanda 163
VN - Vietnam 160
UA - Ucraina 107
IE - Irlanda 97
GB - Regno Unito 91
CA - Canada 70
CI - Costa d'Avorio 55
IN - India 54
SE - Svezia 45
AR - Argentina 37
ES - Italia 34
JP - Giappone 30
PL - Polonia 30
ZA - Sudafrica 27
GR - Grecia 25
KR - Corea 23
MX - Messico 23
MA - Marocco 20
EC - Ecuador 19
BD - Bangladesh 16
ID - Indonesia 16
AT - Austria 15
IR - Iran 12
BG - Bulgaria 11
TR - Turchia 11
CO - Colombia 10
LT - Lituania 10
BE - Belgio 7
EG - Egitto 7
IQ - Iraq 7
PY - Paraguay 7
SA - Arabia Saudita 6
VE - Venezuela 6
CL - Cile 5
PK - Pakistan 5
AE - Emirati Arabi Uniti 4
IL - Israele 4
JM - Giamaica 4
JO - Giordania 4
MY - Malesia 4
SK - Slovacchia (Repubblica Slovacca) 4
TN - Tunisia 4
AZ - Azerbaigian 3
CH - Svizzera 3
DO - Repubblica Dominicana 3
EE - Estonia 3
KE - Kenya 3
LB - Libano 3
PH - Filippine 3
UZ - Uzbekistan 3
AO - Angola 2
AU - Australia 2
BO - Bolivia 2
CZ - Repubblica Ceca 2
EU - Europa 2
HN - Honduras 2
KG - Kirghizistan 2
NO - Norvegia 2
PE - Perù 2
SI - Slovenia 2
TW - Taiwan 2
UY - Uruguay 2
BA - Bosnia-Erzegovina 1
BW - Botswana 1
CR - Costa Rica 1
CY - Cipro 1
DZ - Algeria 1
ET - Etiopia 1
KW - Kuwait 1
KZ - Kazakistan 1
LK - Sri Lanka 1
NG - Nigeria 1
NI - Nicaragua 1
NP - Nepal 1
PT - Portogallo 1
RS - Serbia 1
SV - El Salvador 1
SY - Repubblica araba siriana 1
TT - Trinidad e Tobago 1
TV - Tuvalu 1
ZW - Zimbabwe 1
Totale 11.556
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Città #
Singapore 899
Chandler 433
Moscow 417
Ashburn 391
Beijing 337
Hong Kong 320
Naples 315
Santa Clara 181
Amsterdam 137
Hefei 124
Jacksonville 118
Napoli 113
Millbury 90
Los Angeles 87
Menlo Park 76
Princeton 74
Munich 67
Nanjing 65
Krefeld 57
Boston 55
Ho Chi Minh City 55
São Paulo 46
Wilmington 46
Buffalo 42
Helsinki 41
Redondo Beach 41
Houston 39
Turku 39
Woodbridge 38
Dong Ket 36
Des Moines 35
Ottawa 35
Falkenstein 33
Nuremberg 29
Frankfurt am Main 28
Milan 27
Dallas 26
Hanoi 26
Lawrence 26
Bad Bellingen 25
Rome 24
Seoul 22
Dearborn 21
Nanchang 21
New York 21
San Giorgio a Cremano 20
Brooklyn 19
Salerno 19
Pozzuoli 18
Thessaloniki 18
Redwood City 17
Tokyo 17
Casablanca 16
London 16
Seattle 16
Toronto 16
Chicago 15
Mugnano di Napoli 15
Tianjin 15
Falls Church 14
Hebei 14
Warsaw 14
Dublin 12
Jiaxing 12
Shenyang 12
Trieste 12
Lappeenranta 11
Mexico City 11
Norwalk 11
Rio de Janeiro 11
San Francisco 11
Stockholm 11
Cambridge 10
Johannesburg 10
Phoenix 10
Cervino 9
Chennai 9
Haiphong 9
Indiana 9
New Delhi 9
Scunthorpe 9
Sofia 9
Vienna 9
Ardabil 8
Formia 8
Guangzhou 8
Manchester 8
Montreal 8
Roccarainola 8
Wroclaw 8
Ann Arbor 7
Athens 7
Atlanta 7
Belo Horizonte 7
Boardman 7
Changsha 7
Kronberg 7
Pune 7
Zola Predosa 7
Augusta 6
Totale 5.798
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Nome #
7-nitro-5-fenil-1(pirrolidin-1-ilmetil)-1H-benzo[e][1,4] diazepin-2(3H)-one ed altri composti derivati delle benzodiazepine 365
1,2,4-Thiadiazolidin-3,5-diones as novel hydrogen sulfide donors 310
Design, Synthesis and Biological Evaluation of Novel N-Arylpiperazines Containing a 4,5-Dihydrothiazole Ring 265
Pharmacological characterization of the newly synthesized 5-amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide hydrochloride (BED) as a potent NCX3 inhibitor that worsens anoxic injury in cortical neurons, organotypic hippocampal cultures, and ischemic brain 154
MONTELUKAST ESTERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 147
Chemical Composition of PM10 at Urban Sites in Naples (Italy) 142
Activity of human kallikrein-related peptidase 6 (KLK6) on substrates containing sequences of basic amino acids. Is it a processing protease? 139
Development of 1,2,3-Triazole-Based Sphingosine Kinase Inhibitors and Their Evaluation as Antiproliferative Agents 139
Design of Sphingosine Kinases Inhibitors: Challenges and Recent Developments 135
Synthesis of phenylpyrimidinones as guanylyl cyclase C inhibitors 133
Heavy Metals Size Distribution in PM10 and Environmental-Sanitary Risk Analysis in Acerra (Italy) 131
Antagonizing S1P3 receptor with cell-penetrating pepducins in skeletal muscle fibrosis 126
Antagonizing S1P3 receptor with Cell-Penetrating Pepducins in Skeletal Muscle Fibrosis 126
Acute and long-term NCX activation reduces brain injury and restores behavioral functions in mice subjected to neonatal brain ischemia 123
Synthesis of Arylpiperazine Derivatives as Protease Activated Receptor 1 Antagonists and Their Evaluation as Antiproliferative Agents 120
Synthesis, Chiral Resolution and Enantiomers Absolute Configuration of 4-Nitropropranolol and 7-Nitropropranolol 119
New 5-HT1A, 5HT2Aand 5HT2Creceptor ligands containing a picolinic nucleus: Synthesis, in vitro and in vivo pharmacological evaluation 117
The Role of 5-HT1A Receptor in the Cancer as a New Opportunity in Medicinal Chemistry 117
A convenient synthesis by microwave irradiation of an active metabolite (EXP-3174) of losartan. 116
Synthesis and in Vitro Screening of New Series of 2,6-Dipeptidyl-anthraquinones: Influence of Side Chain Length on HIV-1 Nucleocapsid Inhibitors 116
HYBRIDS BETWEEN H2S-DONORS AND BETAMETHASONE 17-VALERATE OR TRIAMCINOLONE ACETONIDE: IN VITRO EFFECT IN ASTHMA TREATMENT 114
Identification of a pepducin acting as S1P3 receptor antagonist 113
Synthesis and Pharmacological Screening of Pyridopyrimidines as Effective Anti-Diarrheal Agents through the Suppression of Cyclic Nucleotide Accumulation 113
Non-Natural Linker Configuration in 2,6-Dipeptidyl-Anthraquinones Enhances the Inhibition of TAR RNA Binding/Annealing Activities by HIV-1 NC and Tat Proteins 112
Synthesis, in vitro and in vivo pharmacological evaluation of serotoninergic ligands containing an isonicotinic nucleus 111
Hybrids between H2S-donors and betamethasone 17-valerate or triamcinolone acetonide inhibit mast cell degranulation and promote hyperpolarization of bronchial smooth muscle cells 110
Development validation of LC-MS/MS method and determination of pharmacokinetic parameters of the stroke neuroprotectant neurounina-1 in beagle dog plasma after intravenous administration 108
Microwave Assisted Organic Synthesis of Heterocycles in Aqueous Media: Recent Advances in Medicinal Chemistry 107
A New Process for the Synthesis of Budesonide 21-Phosphate and Evaluation in a Murine Model of Inflammation 106
Synthesis, docking studies, and pharmacological evaluation of 5HT 2C ligands containing the N′-cyanoisonicotinamidine or N′-cyanopicolinamidine nucleus 106
Budesonide 21-phosphate sodium salt for use as anti-inflammatory or anti-asthmatic agent. 105
3-Nitroatenolol: First Synthesis, Chiral Resolution and Enantiomers’ Absolute Configuration 105
Level, potential sources of polycyclic aromatic hydrocarbons (PAHs) in particulate matter (PM10) in Naples 105
Anti-metastatic properties of naproxen-HBTA in a murine model of cutaneous melanoma 105
Genetic Up-Regulation or Pharmacological Activation of the Na+/Ca2+ Exchanger 1 (NCX1) Enhances Hippocampal-Dependent Contextual and Spatial Learning and Memory 105
Synthesis, in vitro and in vivo evaluation of 11C-O-methylated arylpiperazines as potential serotonin 1A (5-HT1A) receptor antagonist radiotracers 104
Synthesis of novel anti-inflammatory peptides derived from the amino-acid sequence of the bioactive protein SV-IV 103
A convenient synthesis of N-Fmoc-N,N'-bis-Boc-7-guanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Fmoc-N,N'-bis-Boc-7-guanyl-Tic-OH, GTIC). 103
7-nitro-5-phenyl-1-(pyrrolidin-1-ylmethyl)-1H-benzo[E][1,4]diazepin-2(3H)-one and other benzodiazepine derivatives 103
Beneficial Effects of Two Hydrogen Sulfide (H2S)-Releasing Derivatives of Dexamethasone with Antioxidant Activity on Atopic Dermatitis in Mice 102
Synthesis, Pharmacological Evaluation, and Molecular Modeling Studies of Novel Peptidic CAAX Analogues as Farnesyl-Protein-Transferase Inhibitors 102
Propafenone quantification in human plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry in a bioequivalence study 102
Evidence for a protective role played by Na+-Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats 101
Synthesis, Biological Evaluation and Docking Studies of PAR2-AP Derived Pseudopeptides as Inhibitors of Kallikrein 5 and 6 101
Prednisone-hydrogen sulfide releasing hybrid shows improved therapeutic profile in asthma 100
Conformation-activity relationship of peptide T and new pseudocyclic hexapeptide analogs. 100
Synthesis and In Vitro Pharmacological Evaluation of Novel 2-Hydroxypropyl-4-arylpiperazine Derivatives as Serotoninergic Ligands 100
Isothiocyanate-Corticosteroid Conjugates against asthma: Unity makes strength 99
New Potent 5-HT2A Receptor Ligands Containing a N'-Cyanopicolinamidine Nucleus: Synthesis and In Vitro Pharmacological Evaluation 99
5‑HT1A Receptor: An Old Target as a New Attractive Tool in Drug Discovery from Central Nervous System to Cancer 99
Synthesis by microwave irradiation of a substituted benzoxazine parallel library with preferential relaxant activity for guinea pig trachealis 97
A convenient strategy of dimerization by microwave heating and using 2,5-diketopiperazine as scaffold. 96
New Serotoninergic Ligands Containing Indolic and Methyl Indolic Nuclei: Synthesis and In Vitro Pharmacological Evaluation 96
PCB levels in adipose tissue of dogs from illegal dumping sites in Campania region (Italy) 96
Na+/Ca2+ exchanger isoform 1 takes part to the Ca2+-related prosurvival pathway of SOD1 in primary motor neurons exposed to beta-methylamino-l-alanine 96
Novel tools for the elucidation of physio-pathological role of H2S 95
BUDESONIDE 21-PHOSPHATE SALTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 94
H2s donors and their use in medicinal chemistry 94
A valuable synthesis of reduced peptide bond by microwave irradiation 93
Synthesis, Docking Studies and Pharmacological Evaluation of Serotoninergic Ligands Containing a 5-Norbornene-2-Carboxamide Nucleus 92
Synthesis of benzamide derivatives and their evaluation as antiprion agents 92
Structure-activity relationships study of isothiocyanates for H2S releasing properties: 3-Pyridyl-isothiocyanate as a new promising cardioprotective agent 92
Newly Synthesized Indolylacetic Derivatives Reduce Tumor Necrosis Factor-Mediated Neuroinflammation and Prolong Survival in Amyotrophic Lateral Sclerosis Mice 90
Identification of a novel selective CSE inhibitor through a combined pharmacological and metabolomic approach 89
Synthesis of substituted benzamides as anti-inflammatory agents that inhibit preferentially cyclooxygenase 1 but do not cause gastric damage. 88
Neurounina-1, a Novel Compound that Increases Na+/Ca2+ Exchanger Activity, Effectively Protects Against Stroke Damage 88
Thrombin receptors and their antagonists: an update on the patent literature 87
Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production 87
Trends in h2s-donors chemistry and their effects in cardiovascular diseases 87
Synthesis of Nα-Fmoc N,N′-bis-Boc-5-, 6- and 8-guanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid (5-GTIC, 6-GTIC and 8-GTIC) 86
Microwave Solvent Free Regioselective 1,3 Dipolar Cycloaddition in the Synthesis of 1,4 Substituted [1,2,3]-Triazoles as Amide Bond Isosteres 86
Synthesis and vasorelaxant activity of new 1,4-benzoxazine derivatives potassium channel openers. 86
Synthesis, docking studies, and pharmacological evaluation of 2-hydroxypropyl-4-arylpiperazine derivatives as serotoninergic ligands 86
Synthesis by microwave irradiation and binding properties of novel 5-HT1A receptor ligands. 85
Design, Synthesis and Evaluation of Novel Molecular Hybrids between Antiglaucoma Drugs and H2S Donors 83
Synthesis of 1-naphthylpiperazine derivatives as serotoninergic ligands and their evaluation as antiproliferative agents. 83
Inhibitory effects of bromelain, a cysteine protease derived from pineapple stem (Ananas comosus), on intestinal motility in mice. 82
Arylpiperazine Derivatives and Cancer: A New Challenge in Medicinal Chemistry 81
Enhanced efficacy of formoterol-montelukast salt in relieving asthma features and in preserving β2-agonists rescue therapy 81
Synthesis and structure-activity of antisense peptides corresponding to the region for CaM-binding domain of the inducible nitric oxide synthase 81
Sintesi e caratterizzazione farmacologica di nuovi chemioterapici antitumorali inibitori della farnesil-transferasi 81
PAR1 Antagonism Protects Against Experimental Liver Fibrosis. Role of Proteinase Receptors in Stellate Cell Activation 80
New Insights into the Structure-Activity Relationship and Neuroprotective Profile of Benzodiazepinone Derivatives of Neurounina-1 as Modulators of the Na+/Ca2+Exchanger Isoforms 80
Synthesis of new 1,2,3-benzotriazin-4-one-arylpiperazine derivatives as 5-HT1A serotonin receptor ligands. 79
A nitro-arginine derivative of trimebutine (NO2-Arg-Trim) attenuates pain induced by colorectal distension in conscious rats. 79
Synthetic peptides as probes for conformational preferences of domains of membrane receptors 78
A convenient synthesis by microwave heating and pharmacological evaluation of novel benzoyltriazole and saccharine derivatives as 5-HT1A receptor ligands. 78
Synthesis of 6-beta-D-glucosyl and 6-nitroxy (-)-galanthamine derivatives as acetylcholinesterase inhibitors 77
Rebound effects of NCX3 pharmacological inhibition: A novel strategy to accelerate myelin formation in oligodendrocytes 77
H2S donating corticosteroids: Design, synthesis and biological evaluation in a murine model of asthma 77
New 5-Hydroxytryptamine1A Receptor Ligands Containing a Norbornene Nucleus: Synthesis and in Vitro Pharmacological Evaluation 76
Effect of positive charge in VIP 16g-glutamyl diamino derivatives on hVPAC1 and hVPAC2 receptor function 76
Kallikrein Protease Activated Receptor (PAR) Axis: An Attractive Target for Drug Development 76
Probing the shape of a hydrophobic pocket in the active site of delta-opioid antagonists 75
Design of inhibitors for human tissue kallikrein using non-natural aromatic and basic amino acids. 75
Development and evaluation of nanostructured systems for cutaneous delivery of H2S-releasing corticosteroids for skin inflammatory diseases 73
Synthesis of 2-Methyl-3-indolylacetic Derivatives as Anti-Inflammatory Agents That Inhibit Preferentially Cyclooxygenase 1 without Gastric Damage 73
5-HT2 receptor affinity, docking studies and pharmacological evaluation of a series of 1,3-disubstituted thiourea derivatives 73
Montelukast salts and pharmaceutical compositions containing the same 73
Efficient Microwave Combinatorial Parallel and Non Parallel Synthesis of N-Alkylated Glycine Methyl Esters as Peptide Building Blocks 71
Totale 10.479
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Categoria #
all - tutte 39.898
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 39.898
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021290 0 0 0 0 44 29 40 12 39 12 51 63
2021/2022845 4 3 4 148 19 39 7 31 89 74 191 236
2022/20231.011 126 128 23 109 87 104 18 72 138 131 55 20
2023/20241.189 34 111 170 33 26 22 45 362 205 24 110 47
2024/20253.918 168 194 50 83 94 266 359 274 220 460 1.440 310
2025/20263.168 758 465 794 603 548 0 0 0 0 0 0 0
Totale 11.824