IRIS
SEVERINO, BEATRICE
 Distribuzione geografica
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Continente #
AS - Asia 5.077
NA - Nord America 4.920
EU - Europa 4.697
SA - Sud America 593
AF - Africa 176
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 2
Totale 15.471
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Nazione #
US - Stati Uniti d'America 4.741
SG - Singapore 2.227
RU - Federazione Russa 1.781
IT - Italia 1.238
CN - Cina 1.017
VN - Vietnam 964
DE - Germania 471
BR - Brasile 461
HK - Hong Kong 360
FR - Francia 284
NL - Olanda 181
FI - Finlandia 167
GB - Regno Unito 118
UA - Ucraina 112
CA - Canada 101
IE - Irlanda 99
JP - Giappone 92
IN - India 89
BD - Bangladesh 57
CI - Costa d'Avorio 56
ES - Italia 50
SE - Svezia 48
AR - Argentina 46
ZA - Sudafrica 42
MX - Messico 41
PL - Polonia 40
KR - Corea 31
EC - Ecuador 26
GR - Grecia 26
MA - Marocco 25
PH - Filippine 25
ID - Indonesia 22
IQ - Iraq 22
TH - Thailandia 21
TR - Turchia 20
PK - Pakistan 18
AT - Austria 16
CO - Colombia 16
VE - Venezuela 15
BG - Bulgaria 12
IR - Iran 12
LT - Lituania 12
TW - Taiwan 11
EG - Egitto 10
IL - Israele 10
JO - Giordania 10
PY - Paraguay 10
UZ - Uzbekistan 10
SA - Arabia Saudita 9
TN - Tunisia 9
CL - Cile 8
JM - Giamaica 8
BE - Belgio 7
MY - Malesia 7
AE - Emirati Arabi Uniti 6
AZ - Azerbaigian 5
CH - Svizzera 5
DZ - Algeria 5
LB - Libano 5
UY - Uruguay 5
AU - Australia 4
HN - Honduras 4
KE - Kenya 4
KZ - Kazakistan 4
NI - Nicaragua 4
SK - Slovacchia (Repubblica Slovacca) 4
SY - Repubblica araba siriana 4
AO - Angola 3
BA - Bosnia-Erzegovina 3
CR - Costa Rica 3
DO - Repubblica Dominicana 3
EE - Estonia 3
ET - Etiopia 3
PE - Perù 3
SI - Slovenia 3
TT - Trinidad e Tobago 3
AL - Albania 2
AM - Armenia 2
BO - Bolivia 2
BS - Bahamas 2
CZ - Repubblica Ceca 2
DM - Dominica 2
EU - Europa 2
GA - Gabon 2
GE - Georgia 2
GN - Guinea 2
GT - Guatemala 2
HU - Ungheria 2
KG - Kirghizistan 2
KW - Kuwait 2
LV - Lettonia 2
MG - Madagascar 2
MN - Mongolia 2
NO - Norvegia 2
NP - Nepal 2
OM - Oman 2
PR - Porto Rico 2
PS - Palestinian Territory 2
SN - Senegal 2
BW - Botswana 1
Totale 15.444
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Città #
Singapore 1.099
San Jose 780
Ashburn 558
Chandler 434
Moscow 417
Naples 366
Beijing 356
Hong Kong 342
Ho Chi Minh City 266
Hanoi 205
Santa Clara 196
Amsterdam 149
Hefei 124
The Dalles 121
Jacksonville 119
Los Angeles 118
Napoli 113
Lauterbourg 112
Millbury 90
Menlo Park 76
Princeton 74
Tokyo 71
Munich 67
Nanjing 65
Council Bluffs 62
São Paulo 61
Krefeld 57
Boston 56
New York 55
Buffalo 51
Houston 50
Wilmington 46
Haiphong 43
Frankfurt am Main 42
Helsinki 41
Redondo Beach 41
Dallas 39
Turku 39
Da Nang 38
Woodbridge 38
Dong Ket 36
Des Moines 35
Ottawa 35
Milan 34
Rome 34
Falkenstein 33
Nuremberg 32
Orem 28
Lawrence 26
Bad Bellingen 25
Brooklyn 25
Toronto 25
London 24
Warsaw 23
Chicago 22
Mexico City 22
Seoul 22
Dearborn 21
Johannesburg 21
Nanchang 21
Atlanta 20
Salerno 20
San Giorgio a Cremano 20
Casablanca 19
Pozzuoli 18
Seattle 18
Thessaloniki 18
Redwood City 17
Chennai 16
Phoenix 16
Tianjin 16
Denver 15
Hải Dương 15
Montreal 15
Mugnano di Napoli 15
Rio de Janeiro 15
Dublin 14
Falls Church 14
Hebei 14
Stockholm 14
Manchester 13
Jiaxing 12
Norwalk 12
San Francisco 12
Shenyang 12
Trieste 12
Lappeenranta 11
Biên Hòa 10
Cambridge 10
Can Tho 10
New Delhi 10
Sofia 10
Cervino 9
Indiana 9
Poplar 9
Scunthorpe 9
Vienna 9
Amman 8
Ardabil 8
Bangkok 8
Totale 8.153
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Nome #
7-nitro-5-fenil-1(pirrolidin-1-ilmetil)-1H-benzo[e][1,4] diazepin-2(3H)-one ed altri composti derivati delle benzodiazepine 391
1,2,4-Thiadiazolidin-3,5-diones as novel hydrogen sulfide donors 360
Design, Synthesis and Biological Evaluation of Novel N-Arylpiperazines Containing a 4,5-Dihydrothiazole Ring 302
Development of 1,2,3-Triazole-Based Sphingosine Kinase Inhibitors and Their Evaluation as Antiproliferative Agents 196
Pharmacological characterization of the newly synthesized 5-amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide hydrochloride (BED) as a potent NCX3 inhibitor that worsens anoxic injury in cortical neurons, organotypic hippocampal cultures, and ischemic brain 193
Chemical Composition of PM10 at Urban Sites in Naples (Italy) 184
Activity of human kallikrein-related peptidase 6 (KLK6) on substrates containing sequences of basic amino acids. Is it a processing protease? 182
Synthesis of phenylpyrimidinones as guanylyl cyclase C inhibitors 180
Design of Sphingosine Kinases Inhibitors: Challenges and Recent Developments 171
MONTELUKAST ESTERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 169
Antagonizing S1P3 receptor with cell-penetrating pepducins in skeletal muscle fibrosis 168
Identification of a pepducin acting as S1P3 receptor antagonist 167
Heavy Metals Size Distribution in PM10 and Environmental-Sanitary Risk Analysis in Acerra (Italy) 162
Antagonizing S1P3 receptor with Cell-Penetrating Pepducins in Skeletal Muscle Fibrosis 162
Synthesis, in vitro and in vivo pharmacological evaluation of serotoninergic ligands containing an isonicotinic nucleus 160
Synthesis and in Vitro Screening of New Series of 2,6-Dipeptidyl-anthraquinones: Influence of Side Chain Length on HIV-1 Nucleocapsid Inhibitors 159
The Role of 5-HT1A Receptor in the Cancer as a New Opportunity in Medicinal Chemistry 158
Acute and long-term NCX activation reduces brain injury and restores behavioral functions in mice subjected to neonatal brain ischemia 157
Synthesis, docking studies, and pharmacological evaluation of 5HT 2C ligands containing the N′-cyanoisonicotinamidine or N′-cyanopicolinamidine nucleus 155
A convenient synthesis by microwave irradiation of an active metabolite (EXP-3174) of losartan. 154
HYBRIDS BETWEEN H2S-DONORS AND BETAMETHASONE 17-VALERATE OR TRIAMCINOLONE ACETONIDE: IN VITRO EFFECT IN ASTHMA TREATMENT 154
Synthesis of Arylpiperazine Derivatives as Protease Activated Receptor 1 Antagonists and Their Evaluation as Antiproliferative Agents 153
New 5-HT1A, 5HT2Aand 5HT2Creceptor ligands containing a picolinic nucleus: Synthesis, in vitro and in vivo pharmacological evaluation 153
Synthesis and Pharmacological Screening of Pyridopyrimidines as Effective Anti-Diarrheal Agents through the Suppression of Cyclic Nucleotide Accumulation 151
Synthesis, Chiral Resolution and Enantiomers Absolute Configuration of 4-Nitropropranolol and 7-Nitropropranolol 150
Non-Natural Linker Configuration in 2,6-Dipeptidyl-Anthraquinones Enhances the Inhibition of TAR RNA Binding/Annealing Activities by HIV-1 NC and Tat Proteins 149
A New Process for the Synthesis of Budesonide 21-Phosphate and Evaluation in a Murine Model of Inflammation 148
Propafenone quantification in human plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry in a bioequivalence study 146
Synthesis, Biological Evaluation and Docking Studies of PAR2-AP Derived Pseudopeptides as Inhibitors of Kallikrein 5 and 6 145
Development validation of LC-MS/MS method and determination of pharmacokinetic parameters of the stroke neuroprotectant neurounina-1 in beagle dog plasma after intravenous administration 145
Isothiocyanate-Corticosteroid Conjugates against asthma: Unity makes strength 143
Hybrids between H2S-donors and betamethasone 17-valerate or triamcinolone acetonide inhibit mast cell degranulation and promote hyperpolarization of bronchial smooth muscle cells 143
5‑HT1A Receptor: An Old Target as a New Attractive Tool in Drug Discovery from Central Nervous System to Cancer 141
Level, potential sources of polycyclic aromatic hydrocarbons (PAHs) in particulate matter (PM10) in Naples 141
New Potent 5-HT2A Receptor Ligands Containing a N'-Cyanopicolinamidine Nucleus: Synthesis and In Vitro Pharmacological Evaluation 140
Genetic Up-Regulation or Pharmacological Activation of the Na+/Ca2+ Exchanger 1 (NCX1) Enhances Hippocampal-Dependent Contextual and Spatial Learning and Memory 139
PCB levels in adipose tissue of dogs from illegal dumping sites in Campania region (Italy) 139
3-Nitroatenolol: First Synthesis, Chiral Resolution and Enantiomers’ Absolute Configuration 137
Synthesis and In Vitro Pharmacological Evaluation of Novel 2-Hydroxypropyl-4-arylpiperazine Derivatives as Serotoninergic Ligands 137
Microwave Assisted Organic Synthesis of Heterocycles in Aqueous Media: Recent Advances in Medicinal Chemistry 137
Prednisone-hydrogen sulfide releasing hybrid shows improved therapeutic profile in asthma 136
Evidence for a protective role played by Na+-Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats 135
New Serotoninergic Ligands Containing Indolic and Methyl Indolic Nuclei: Synthesis and In Vitro Pharmacological Evaluation 135
Novel tools for the elucidation of physio-pathological role of H2S 134
Newly Synthesized Indolylacetic Derivatives Reduce Tumor Necrosis Factor-Mediated Neuroinflammation and Prolong Survival in Amyotrophic Lateral Sclerosis Mice 133
Beneficial Effects of Two Hydrogen Sulfide (H2S)-Releasing Derivatives of Dexamethasone with Antioxidant Activity on Atopic Dermatitis in Mice 132
A convenient strategy of dimerization by microwave heating and using 2,5-diketopiperazine as scaffold. 132
7-nitro-5-phenyl-1-(pyrrolidin-1-ylmethyl)-1H-benzo[E][1,4]diazepin-2(3H)-one and other benzodiazepine derivatives 131
Synthesis, Docking Studies and Pharmacological Evaluation of Serotoninergic Ligands Containing a 5-Norbornene-2-Carboxamide Nucleus 130
Synthesis, Pharmacological Evaluation, and Molecular Modeling Studies of Novel Peptidic CAAX Analogues as Farnesyl-Protein-Transferase Inhibitors 130
Synthesis, in vitro and in vivo evaluation of 11C-O-methylated arylpiperazines as potential serotonin 1A (5-HT1A) receptor antagonist radiotracers 130
Anti-metastatic properties of naproxen-HBTA in a murine model of cutaneous melanoma 128
Synthesis of novel anti-inflammatory peptides derived from the amino-acid sequence of the bioactive protein SV-IV 127
Conformation-activity relationship of peptide T and new pseudocyclic hexapeptide analogs. 126
Synthesis of benzamide derivatives and their evaluation as antiprion agents 126
Na+/Ca2+ exchanger isoform 1 takes part to the Ca2+-related prosurvival pathway of SOD1 in primary motor neurons exposed to beta-methylamino-l-alanine 126
Arylpiperazine Derivatives and Cancer: A New Challenge in Medicinal Chemistry 124
Budesonide 21-phosphate sodium salt for use as anti-inflammatory or anti-asthmatic agent. 123
Synthesis by microwave irradiation of a substituted benzoxazine parallel library with preferential relaxant activity for guinea pig trachealis 123
A convenient synthesis of N-Fmoc-N,N'-bis-Boc-7-guanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Fmoc-N,N'-bis-Boc-7-guanyl-Tic-OH, GTIC). 122
Synthesis of 1-naphthylpiperazine derivatives as serotoninergic ligands and their evaluation as antiproliferative agents. 122
H2s donors and their use in medicinal chemistry 122
BUDESONIDE 21-PHOSPHATE SALTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 121
Design, Synthesis and Evaluation of Novel Molecular Hybrids between Antiglaucoma Drugs and H2S Donors 119
Structure-activity relationships study of isothiocyanates for H2S releasing properties: 3-Pyridyl-isothiocyanate as a new promising cardioprotective agent 118
A valuable synthesis of reduced peptide bond by microwave irradiation 116
Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production 116
Synthesis and vasorelaxant activity of new 1,4-benzoxazine derivatives potassium channel openers. 115
Trends in h2s-donors chemistry and their effects in cardiovascular diseases 115
Thrombin receptors and their antagonists: an update on the patent literature 114
Identification of a novel selective CSE inhibitor through a combined pharmacological and metabolomic approach 114
Synthesis of Nα-Fmoc N,N′-bis-Boc-5-, 6- and 8-guanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid (5-GTIC, 6-GTIC and 8-GTIC) 112
Synthesis of new 1,2,3-benzotriazin-4-one-arylpiperazine derivatives as 5-HT1A serotonin receptor ligands. 112
A convenient synthesis by microwave heating and pharmacological evaluation of novel benzoyltriazole and saccharine derivatives as 5-HT1A receptor ligands. 111
Synthesis of substituted benzamides as anti-inflammatory agents that inhibit preferentially cyclooxygenase 1 but do not cause gastric damage. 111
Kallikrein Protease Activated Receptor (PAR) Axis: An Attractive Target for Drug Development 111
Sintesi e caratterizzazione farmacologica di nuovi chemioterapici antitumorali inibitori della farnesil-transferasi 111
Synthesis, docking studies, and pharmacological evaluation of 2-hydroxypropyl-4-arylpiperazine derivatives as serotoninergic ligands 111
Rebound effects of NCX3 pharmacological inhibition: A novel strategy to accelerate myelin formation in oligodendrocytes 108
Microwave Solvent Free Regioselective 1,3 Dipolar Cycloaddition in the Synthesis of 1,4 Substituted [1,2,3]-Triazoles as Amide Bond Isosteres 107
New 5-Hydroxytryptamine1A Receptor Ligands Containing a Norbornene Nucleus: Synthesis and in Vitro Pharmacological Evaluation 107
Synthesis and structure-activity of antisense peptides corresponding to the region for CaM-binding domain of the inducible nitric oxide synthase 107
Synthesis by microwave irradiation and binding properties of novel 5-HT1A receptor ligands. 107
H2S donating corticosteroids: Design, synthesis and biological evaluation in a murine model of asthma 107
Enhanced efficacy of formoterol-montelukast salt in relieving asthma features and in preserving β2-agonists rescue therapy 106
Neurounina-1, a Novel Compound that Increases Na+/Ca2+ Exchanger Activity, Effectively Protects Against Stroke Damage 106
Development and evaluation of nanostructured systems for cutaneous delivery of H2S-releasing corticosteroids for skin inflammatory diseases 105
Synthetic peptides as probes for conformational preferences of domains of membrane receptors 105
A nitro-arginine derivative of trimebutine (NO2-Arg-Trim) attenuates pain induced by colorectal distension in conscious rats. 105
The identification of adenylyl cyclase modulators as potential receptors for 6-nitrodopamine in human-induced pluripotent stem cell (hiPSC)-derived cardiomyocytes and their relevance in heart inotropism 104
PAR1 Antagonism Protects Against Experimental Liver Fibrosis. Role of Proteinase Receptors in Stellate Cell Activation 104
Inhibitory effects of bromelain, a cysteine protease derived from pineapple stem (Ananas comosus), on intestinal motility in mice. 103
Probing the shape of a hydrophobic pocket in the active site of delta-opioid antagonists 102
Minimal structural requirements for agonist activity of PAR-2 activating peptides. 101
Effect of positive charge in VIP 16g-glutamyl diamino derivatives on hVPAC1 and hVPAC2 receptor function 100
Efficient Microwave Combinatorial Parallel and Non Parallel Synthesis of N-Alkylated Glycine Methyl Esters as Peptide Building Blocks 99
Probing the shape of a hydrophobic pocket in the active site of delta-opioid antagonists 99
Synthesis of 6-beta-D-glucosyl and 6-nitroxy (-)-galanthamine derivatives as acetylcholinesterase inhibitors 98
Synthesis and biological activity of pseudopeptides inhibitors of Ras farnesyl transferase containing unconventional amino acids. 97
Pills of Multi-Target H2S Donating Molecules for Complex Diseases 97
Totale 13.749
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Categoria #
all - tutte 48.238
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 48.238
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202163 0 0 0 0 0 0 0 0 0 0 0 63
2021/2022845 4 3 4 148 19 39 7 31 89 74 191 236
2022/20231.011 126 128 23 109 87 104 18 72 138 131 55 20
2023/20241.189 34 111 170 33 26 22 45 362 205 24 110 47
2024/20253.918 168 194 50 83 94 266 359 274 220 460 1.440 310
2025/20267.094 758 465 794 609 1.272 257 842 374 969 505 242 7
Totale 15.750