IRIS
SEVERINO, BEATRICE
 Distribuzione geografica
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Continente #
EU - Europa 4.384
AS - Asia 3.826
NA - Nord America 3.465
SA - Sud America 540
AF - Africa 153
OC - Oceania 4
Continente sconosciuto - Info sul continente non disponibili 2
Totale 12.374
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Nazione #
US - Stati Uniti d'America 3.328
SG - Singapore 2.087
RU - Federazione Russa 1.779
IT - Italia 1.121
CN - Cina 932
DE - Germania 452
BR - Brasile 430
HK - Hong Kong 324
VN - Vietnam 210
FR - Francia 173
FI - Finlandia 167
NL - Olanda 165
UA - Ucraina 109
GB - Regno Unito 99
IE - Irlanda 97
CA - Canada 75
IN - India 60
CI - Costa d'Avorio 56
SE - Svezia 48
ES - Italia 43
AR - Argentina 41
JP - Giappone 37
PL - Polonia 34
ZA - Sudafrica 34
MX - Messico 30
GR - Grecia 26
EC - Ecuador 24
KR - Corea 23
MA - Marocco 23
BD - Bangladesh 22
ID - Indonesia 20
AT - Austria 15
TR - Turchia 13
IR - Iran 12
BG - Bulgaria 11
CO - Colombia 11
IQ - Iraq 11
LT - Lituania 10
PK - Pakistan 10
PY - Paraguay 10
BE - Belgio 7
EG - Egitto 7
TN - Tunisia 7
VE - Venezuela 7
AE - Emirati Arabi Uniti 6
CL - Cile 6
JM - Giamaica 6
JO - Giordania 6
SA - Arabia Saudita 6
UZ - Uzbekistan 6
AZ - Azerbaigian 5
IL - Israele 5
MY - Malesia 5
UY - Uruguay 5
LB - Libano 4
NI - Nicaragua 4
SK - Slovacchia (Repubblica Slovacca) 4
AO - Angola 3
BA - Bosnia-Erzegovina 3
CH - Svizzera 3
CR - Costa Rica 3
DO - Repubblica Dominicana 3
EE - Estonia 3
HN - Honduras 3
KE - Kenya 3
PE - Perù 3
PH - Filippine 3
AL - Albania 2
AU - Australia 2
BO - Bolivia 2
CZ - Repubblica Ceca 2
DM - Dominica 2
DZ - Algeria 2
ET - Etiopia 2
EU - Europa 2
GE - Georgia 2
GN - Guinea 2
GT - Guatemala 2
KG - Kirghizistan 2
LV - Lettonia 2
MG - Madagascar 2
MN - Mongolia 2
NO - Norvegia 2
PR - Porto Rico 2
SI - Slovenia 2
SY - Repubblica araba siriana 2
TT - Trinidad e Tobago 2
TW - Taiwan 2
AM - Armenia 1
BS - Bahamas 1
BW - Botswana 1
CD - Congo 1
CM - Camerun 1
CU - Cuba 1
CV - Capo Verde 1
CY - Cipro 1
GA - Gabon 1
GY - Guiana 1
HU - Ungheria 1
KH - Cambogia 1
Totale 12.352
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Città #
Singapore 1.003
Ashburn 455
Chandler 433
Moscow 417
Beijing 339
Hong Kong 324
Naples 320
Santa Clara 186
Amsterdam 138
Hefei 124
Jacksonville 118
Napoli 113
Los Angeles 101
Millbury 90
Menlo Park 76
Ho Chi Minh City 74
Princeton 74
Munich 67
Nanjing 65
Krefeld 57
Boston 55
São Paulo 52
Wilmington 46
Buffalo 45
Houston 43
Helsinki 41
Redondo Beach 41
Turku 39
Woodbridge 38
Hanoi 37
Dong Ket 36
Des Moines 35
Ottawa 35
Falkenstein 33
New York 33
Nuremberg 30
Frankfurt am Main 29
Milan 29
Dallas 28
The Dalles 27
Lawrence 26
Bad Bellingen 25
Rome 25
Tokyo 24
Brooklyn 22
Seoul 22
Dearborn 21
Nanchang 21
San Giorgio a Cremano 20
London 19
Salerno 19
Casablanca 18
Pozzuoli 18
Thessaloniki 18
Redwood City 17
Seattle 17
Toronto 17
Warsaw 17
Chicago 16
Johannesburg 16
Mexico City 16
Mugnano di Napoli 15
Tianjin 15
Falls Church 14
Hebei 14
Stockholm 14
Chennai 13
Atlanta 12
Da Nang 12
Dublin 12
Jiaxing 12
Phoenix 12
Rio de Janeiro 12
Shenyang 12
Trieste 12
Denver 11
Haiphong 11
Lappeenranta 11
Norwalk 11
San Francisco 11
Cambridge 10
Manchester 10
Montreal 10
Orem 10
Cervino 9
Indiana 9
New Delhi 9
Scunthorpe 9
Sofia 9
Vienna 9
Ardabil 8
Formia 8
Guangzhou 8
Roccarainola 8
Wroclaw 8
Ann Arbor 7
Athens 7
Belo Horizonte 7
Boardman 7
Changsha 7
Totale 6.145
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Nome #
7-nitro-5-fenil-1(pirrolidin-1-ilmetil)-1H-benzo[e][1,4] diazepin-2(3H)-one ed altri composti derivati delle benzodiazepine 373
1,2,4-Thiadiazolidin-3,5-diones as novel hydrogen sulfide donors 321
Design, Synthesis and Biological Evaluation of Novel N-Arylpiperazines Containing a 4,5-Dihydrothiazole Ring 272
Pharmacological characterization of the newly synthesized 5-amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide hydrochloride (BED) as a potent NCX3 inhibitor that worsens anoxic injury in cortical neurons, organotypic hippocampal cultures, and ischemic brain 162
Chemical Composition of PM10 at Urban Sites in Naples (Italy) 153
Development of 1,2,3-Triazole-Based Sphingosine Kinase Inhibitors and Their Evaluation as Antiproliferative Agents 153
Activity of human kallikrein-related peptidase 6 (KLK6) on substrates containing sequences of basic amino acids. Is it a processing protease? 150
MONTELUKAST ESTERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 150
Design of Sphingosine Kinases Inhibitors: Challenges and Recent Developments 142
Synthesis of phenylpyrimidinones as guanylyl cyclase C inhibitors 140
Heavy Metals Size Distribution in PM10 and Environmental-Sanitary Risk Analysis in Acerra (Italy) 137
Acute and long-term NCX activation reduces brain injury and restores behavioral functions in mice subjected to neonatal brain ischemia 135
Antagonizing S1P3 receptor with cell-penetrating pepducins in skeletal muscle fibrosis 133
Antagonizing S1P3 receptor with Cell-Penetrating Pepducins in Skeletal Muscle Fibrosis 131
Synthesis of Arylpiperazine Derivatives as Protease Activated Receptor 1 Antagonists and Their Evaluation as Antiproliferative Agents 129
Synthesis, Chiral Resolution and Enantiomers Absolute Configuration of 4-Nitropropranolol and 7-Nitropropranolol 127
Synthesis and in Vitro Screening of New Series of 2,6-Dipeptidyl-anthraquinones: Influence of Side Chain Length on HIV-1 Nucleocapsid Inhibitors 126
New 5-HT1A, 5HT2Aand 5HT2Creceptor ligands containing a picolinic nucleus: Synthesis, in vitro and in vivo pharmacological evaluation 126
The Role of 5-HT1A Receptor in the Cancer as a New Opportunity in Medicinal Chemistry 123
A convenient synthesis by microwave irradiation of an active metabolite (EXP-3174) of losartan. 122
Identification of a pepducin acting as S1P3 receptor antagonist 122
Synthesis and Pharmacological Screening of Pyridopyrimidines as Effective Anti-Diarrheal Agents through the Suppression of Cyclic Nucleotide Accumulation 122
Synthesis, in vitro and in vivo pharmacological evaluation of serotoninergic ligands containing an isonicotinic nucleus 121
HYBRIDS BETWEEN H2S-DONORS AND BETAMETHASONE 17-VALERATE OR TRIAMCINOLONE ACETONIDE: IN VITRO EFFECT IN ASTHMA TREATMENT 121
Non-Natural Linker Configuration in 2,6-Dipeptidyl-Anthraquinones Enhances the Inhibition of TAR RNA Binding/Annealing Activities by HIV-1 NC and Tat Proteins 119
Development validation of LC-MS/MS method and determination of pharmacokinetic parameters of the stroke neuroprotectant neurounina-1 in beagle dog plasma after intravenous administration 117
Hybrids between H2S-donors and betamethasone 17-valerate or triamcinolone acetonide inhibit mast cell degranulation and promote hyperpolarization of bronchial smooth muscle cells 117
A New Process for the Synthesis of Budesonide 21-Phosphate and Evaluation in a Murine Model of Inflammation 115
Level, potential sources of polycyclic aromatic hydrocarbons (PAHs) in particulate matter (PM10) in Naples 115
Synthesis, docking studies, and pharmacological evaluation of 5HT 2C ligands containing the N′-cyanoisonicotinamidine or N′-cyanopicolinamidine nucleus 113
3-Nitroatenolol: First Synthesis, Chiral Resolution and Enantiomers’ Absolute Configuration 112
Microwave Assisted Organic Synthesis of Heterocycles in Aqueous Media: Recent Advances in Medicinal Chemistry 112
Propafenone quantification in human plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry in a bioequivalence study 112
Anti-metastatic properties of naproxen-HBTA in a murine model of cutaneous melanoma 112
Synthesis, Pharmacological Evaluation, and Molecular Modeling Studies of Novel Peptidic CAAX Analogues as Farnesyl-Protein-Transferase Inhibitors 111
Synthesis, Biological Evaluation and Docking Studies of PAR2-AP Derived Pseudopeptides as Inhibitors of Kallikrein 5 and 6 111
Genetic Up-Regulation or Pharmacological Activation of the Na+/Ca2+ Exchanger 1 (NCX1) Enhances Hippocampal-Dependent Contextual and Spatial Learning and Memory 111
Synthesis, in vitro and in vivo evaluation of 11C-O-methylated arylpiperazines as potential serotonin 1A (5-HT1A) receptor antagonist radiotracers 111
Budesonide 21-phosphate sodium salt for use as anti-inflammatory or anti-asthmatic agent. 110
Isothiocyanate-Corticosteroid Conjugates against asthma: Unity makes strength 110
Beneficial Effects of Two Hydrogen Sulfide (H2S)-Releasing Derivatives of Dexamethasone with Antioxidant Activity on Atopic Dermatitis in Mice 110
Synthesis of novel anti-inflammatory peptides derived from the amino-acid sequence of the bioactive protein SV-IV 110
A convenient synthesis of N-Fmoc-N,N'-bis-Boc-7-guanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Fmoc-N,N'-bis-Boc-7-guanyl-Tic-OH, GTIC). 110
7-nitro-5-phenyl-1-(pyrrolidin-1-ylmethyl)-1H-benzo[E][1,4]diazepin-2(3H)-one and other benzodiazepine derivatives 110
Prednisone-hydrogen sulfide releasing hybrid shows improved therapeutic profile in asthma 108
Evidence for a protective role played by Na+-Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats 108
Synthesis and In Vitro Pharmacological Evaluation of Novel 2-Hydroxypropyl-4-arylpiperazine Derivatives as Serotoninergic Ligands 108
A convenient strategy of dimerization by microwave heating and using 2,5-diketopiperazine as scaffold. 107
Synthesis by microwave irradiation of a substituted benzoxazine parallel library with preferential relaxant activity for guinea pig trachealis 106
Conformation-activity relationship of peptide T and new pseudocyclic hexapeptide analogs. 106
New Potent 5-HT2A Receptor Ligands Containing a N'-Cyanopicolinamidine Nucleus: Synthesis and In Vitro Pharmacological Evaluation 106
5‑HT1A Receptor: An Old Target as a New Attractive Tool in Drug Discovery from Central Nervous System to Cancer 106
Synthesis, Docking Studies and Pharmacological Evaluation of Serotoninergic Ligands Containing a 5-Norbornene-2-Carboxamide Nucleus 104
Novel tools for the elucidation of physio-pathological role of H2S 104
Na+/Ca2+ exchanger isoform 1 takes part to the Ca2+-related prosurvival pathway of SOD1 in primary motor neurons exposed to beta-methylamino-l-alanine 104
H2s donors and their use in medicinal chemistry 103
A valuable synthesis of reduced peptide bond by microwave irradiation 101
New Serotoninergic Ligands Containing Indolic and Methyl Indolic Nuclei: Synthesis and In Vitro Pharmacological Evaluation 101
PCB levels in adipose tissue of dogs from illegal dumping sites in Campania region (Italy) 101
Newly Synthesized Indolylacetic Derivatives Reduce Tumor Necrosis Factor-Mediated Neuroinflammation and Prolong Survival in Amyotrophic Lateral Sclerosis Mice 101
Synthesis of benzamide derivatives and their evaluation as antiprion agents 100
Structure-activity relationships study of isothiocyanates for H2S releasing properties: 3-Pyridyl-isothiocyanate as a new promising cardioprotective agent 99
BUDESONIDE 21-PHOSPHATE SALTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 99
Synthesis of Nα-Fmoc N,N′-bis-Boc-5-, 6- and 8-guanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid (5-GTIC, 6-GTIC and 8-GTIC) 95
Neurounina-1, a Novel Compound that Increases Na+/Ca2+ Exchanger Activity, Effectively Protects Against Stroke Damage 95
Synthesis of substituted benzamides as anti-inflammatory agents that inhibit preferentially cyclooxygenase 1 but do not cause gastric damage. 94
Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production 94
Synthesis and vasorelaxant activity of new 1,4-benzoxazine derivatives potassium channel openers. 93
Trends in h2s-donors chemistry and their effects in cardiovascular diseases 93
Identification of a novel selective CSE inhibitor through a combined pharmacological and metabolomic approach 92
Design, Synthesis and Evaluation of Novel Molecular Hybrids between Antiglaucoma Drugs and H2S Donors 91
Microwave Solvent Free Regioselective 1,3 Dipolar Cycloaddition in the Synthesis of 1,4 Substituted [1,2,3]-Triazoles as Amide Bond Isosteres 91
Thrombin receptors and their antagonists: an update on the patent literature 91
Synthesis of 1-naphthylpiperazine derivatives as serotoninergic ligands and their evaluation as antiproliferative agents. 91
Synthesis, docking studies, and pharmacological evaluation of 2-hydroxypropyl-4-arylpiperazine derivatives as serotoninergic ligands 91
Arylpiperazine Derivatives and Cancer: A New Challenge in Medicinal Chemistry 89
Enhanced efficacy of formoterol-montelukast salt in relieving asthma features and in preserving β2-agonists rescue therapy 89
Synthesis of new 1,2,3-benzotriazin-4-one-arylpiperazine derivatives as 5-HT1A serotonin receptor ligands. 88
Inhibitory effects of bromelain, a cysteine protease derived from pineapple stem (Ananas comosus), on intestinal motility in mice. 88
Sintesi e caratterizzazione farmacologica di nuovi chemioterapici antitumorali inibitori della farnesil-transferasi 88
PAR1 Antagonism Protects Against Experimental Liver Fibrosis. Role of Proteinase Receptors in Stellate Cell Activation 87
Synthesis by microwave irradiation and binding properties of novel 5-HT1A receptor ligands. 87
H2S donating corticosteroids: Design, synthesis and biological evaluation in a murine model of asthma 87
Synthetic peptides as probes for conformational preferences of domains of membrane receptors 85
New 5-Hydroxytryptamine1A Receptor Ligands Containing a Norbornene Nucleus: Synthesis and in Vitro Pharmacological Evaluation 85
A nitro-arginine derivative of trimebutine (NO2-Arg-Trim) attenuates pain induced by colorectal distension in conscious rats. 84
Rebound effects of NCX3 pharmacological inhibition: A novel strategy to accelerate myelin formation in oligodendrocytes 84
Synthesis and structure-activity of antisense peptides corresponding to the region for CaM-binding domain of the inducible nitric oxide synthase 83
Kallikrein Protease Activated Receptor (PAR) Axis: An Attractive Target for Drug Development 83
New Insights into the Structure-Activity Relationship and Neuroprotective Profile of Benzodiazepinone Derivatives of Neurounina-1 as Modulators of the Na+/Ca2+Exchanger Isoforms 83
Probing the shape of a hydrophobic pocket in the active site of delta-opioid antagonists 81
Effect of positive charge in VIP 16g-glutamyl diamino derivatives on hVPAC1 and hVPAC2 receptor function 81
A convenient synthesis by microwave heating and pharmacological evaluation of novel benzoyltriazole and saccharine derivatives as 5-HT1A receptor ligands. 81
Synthesis and biological activity of pseudopeptides inhibitors of Ras farnesyl transferase containing unconventional amino acids. 80
Design of inhibitors for human tissue kallikrein using non-natural aromatic and basic amino acids. 80
Development and evaluation of nanostructured systems for cutaneous delivery of H2S-releasing corticosteroids for skin inflammatory diseases 79
Synthesis of 6-beta-D-glucosyl and 6-nitroxy (-)-galanthamine derivatives as acetylcholinesterase inhibitors 78
Efficient Microwave Combinatorial Parallel and Non Parallel Synthesis of N-Alkylated Glycine Methyl Esters as Peptide Building Blocks 77
Probing the shape of a hydrophobic pocket in the active site of delta-opioid antagonists 77
5-HT2 receptor affinity, docking studies and pharmacological evaluation of a series of 1,3-disubstituted thiourea derivatives 77
Totale 11.203
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Categoria #
all - tutte 41.016
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 41.016
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021246 0 0 0 0 0 29 40 12 39 12 51 63
2021/2022845 4 3 4 148 19 39 7 31 89 74 191 236
2022/20231.011 126 128 23 109 87 104 18 72 138 131 55 20
2023/20241.189 34 111 170 33 26 22 45 362 205 24 110 47
2024/20253.918 168 194 50 83 94 266 359 274 220 460 1.440 310
2025/20263.986 758 465 794 603 1.250 116 0 0 0 0 0 0
Totale 12.642