The present invention describes compounds of formula (I), and in particular the 7- nitro-5-phenyl-1 -(pyrrolidin-1 - ylmethyl)-1 H-benzo[e][1,4]diazepin-2(3H)-one compound and their pharmaceuticall acceptable salts. The compounds of the invention are useful for medical use, particularly as active ingredient potentially useful for the treatment of cerebral ischemia and other disease characterized by deregulation of sodium and calcium homeostasis

7-nitro-5-phenyl-1-(pyrrolidin-1-ylmethyl)-1H-benzo[E][1,4]diazepin-2(3H)-one and other benzodiazepine derivatives

PIGNATARO, GIUSEPPE;ANNUNZIATO, LUCIO;MOLINARO, PASQUALE;SCORZIELLO, ANTONELLA;SECONDO, AGNESE;PANNACCIONE, ANNA;CUOMO, ORNELLA;CANTILE, MARIA;DI RENZO, GIANFRANCO MARIA LUIGI;CALIENDO, GIUSEPPE;SANTAGADA, VINCENZO;SEVERINO, BEATRICE;FIORINO, FERDINANDO
2012

Abstract

The present invention describes compounds of formula (I), and in particular the 7- nitro-5-phenyl-1 -(pyrrolidin-1 - ylmethyl)-1 H-benzo[e][1,4]diazepin-2(3H)-one compound and their pharmaceuticall acceptable salts. The compounds of the invention are useful for medical use, particularly as active ingredient potentially useful for the treatment of cerebral ischemia and other disease characterized by deregulation of sodium and calcium homeostasis
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/517079
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