IRIS
SECONDO, AGNESE
 Distribuzione geografica
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Continente #
NA - Nord America 2.971
EU - Europa 1.979
AS - Asia 486
AF - Africa 71
SA - Sud America 4
Continente sconosciuto - Info sul continente non disponibili 2
Totale 5.513
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Nazione #
US - Stati Uniti d'America 2.896
IT - Italia 946
CN - Cina 359
UA - Ucraina 233
DE - Germania 221
NL - Olanda 166
FI - Finlandia 124
IE - Irlanda 117
CI - Costa d'Avorio 71
CA - Canada 69
GB - Regno Unito 64
VN - Vietnam 40
SE - Svezia 37
FR - Francia 25
HK - Hong Kong 21
IN - India 18
CH - Svizzera 11
TR - Turchia 11
ES - Italia 10
SG - Singapore 10
JP - Giappone 8
BE - Belgio 7
IR - Iran 6
MX - Messico 6
IL - Israele 4
PL - Polonia 4
AT - Austria 3
CL - Cile 3
RU - Federazione Russa 3
BG - Bulgaria 2
EU - Europa 2
NO - Norvegia 2
PK - Pakistan 2
SA - Arabia Saudita 2
DK - Danimarca 1
HU - Ungheria 1
ID - Indonesia 1
KG - Kirghizistan 1
KR - Corea 1
PE - Perù 1
PH - Filippine 1
PT - Portogallo 1
RO - Romania 1
TW - Taiwan 1
Totale 5.513
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Città #
Chandler 599
Ashburn 390
Jacksonville 234
Napoli 188
Amsterdam 162
Millbury 153
Princeton 124
Nanjing 108
Beijing 103
Boston 90
Naples 76
Ottawa 63
Wilmington 63
Dong Ket 40
Des Moines 39
Lawrence 38
Dearborn 37
Formia 36
Rome 28
Nanchang 27
Norwalk 20
Salerno 20
Hebei 17
Shenyang 16
Changsha 15
Kronberg 15
Milan 14
Seattle 14
Tianjin 14
Houston 13
Jiaxing 13
Pavullo Nel Frignano 13
Portici 13
Woodbridge 13
Caserta 12
Dublin 11
Falls Church 11
Parma 11
Washington 11
Abano Terme 10
Boardman 9
Pune 9
Sudbury 9
Redwood City 8
Augusta 7
Castel Campagnano 7
Highland Park 7
Valladolid 7
Cambridge 6
Fairfield 6
Frankfurt am Main 6
Los Angeles 6
Menlo Park 6
Florence 5
Guangzhou 5
Hong Kong 5
Kunming 5
Mountain View 5
Sant'arpino 5
Toronto 5
Turin 5
Ann Arbor 4
Barano d'Ischia 4
Bari 4
Baronissi 4
Bologna 4
Brugg 4
Courcelles 4
Hangzhou 4
Hefei 4
Indiana 4
Lappeenranta 4
Orange 4
Pompei 4
Brussels 3
Changchun 3
Edinburgh 3
Fremont 3
Jinan 3
Monza 3
Mugnano di Napoli 3
New York 3
Nola 3
Nottingham 3
Padova 3
Palermo 3
San Mateo 3
Taizhou 3
Torino 3
Tower Hamlets 3
Vietri Sul Mare 3
Walnut 3
Warsaw 3
Afragola 2
Agropoli 2
Arce 2
Ardabil 2
Ariano Irpino 2
Avellino 2
Benevento 2
Totale 3.130
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Nome #
7-nitro-5-fenil-1(pirrolidin-1-ilmetil)-1H-benzo[e][1,4] diazepin-2(3H)-one ed altri composti derivati delle benzodiazepine 313
Studio del ruolo della proteina AKAP121 nel controllo della funzionalità mitocondriale in modelli cellulari di anossia/reossigenazione come bersaglio per lo sviluppo di molecole di potenziale impiego terapeutico nell'ischemia cerebrale 262
The pharmacological activation of Mucolipin TRP channel 1 (TRPML1) protects motor neurons exposed to the cycad neurotoxin L-BMAA by promoting autophagic clearance 88
Profarmaci dell’arginina con elevata attività terapeutica 84
Na+/Ca2+ exchanger 1 on nuclear envelope controls PTEN/Akt pathway via nucleoplasmic Ca2+ regulation during neuronal differentiation 71
ncx1, ncx2, and ncx3 gene product expression and function in neuronal anoxia and brain ischemia. 63
A critical role for the potassium-dependent sodium-calcium exchanger NCKX2 in protection against focal ischemic brain damage. 60
7-nitro-5-phenyl-1-(pyrrolidin-1-ylmethyl)-1H-benzo[E][1,4]diazepin-2(3H)-one and other benzodiazepine derivatives 57
Neuronal NCX1 overexpression induces stroke resistance while knockout induces vulnerability via Akt 57
The functional coupling between endoplasmic reticulum and lysosomes for intracellular Ca2+ handling is disrupted in brain ischemia 57
Involvement of the nitric oxide/protein kinase G pathway in polychlorinated biphenyl-induced cell death in SH-SY 5Y neuroblastoma cells 55
Zinc inhibits calcium-mediated and nitric oxide-mediated ion secretion in human enterocytes 55
ApoSOD1 lacking dismutase activity neuroprotects motor neurons exposed to beta-methylamino-L-alanine through the Ca(2+)/Akt/ERK1/2 prosurvival pathway 55
Human lung-resident macrophages express CB1 and CB2 receptors whose activation inhibits the release of angiogenic and lymphangiogenic factors. STAIANO and LOFFREDO are CO-FIRST AUTHORS. 54
NCX1 Exchanger Cooperates with Calretinin to Confer Preconditioning-Induced Tolerance Against Cerebral Ischemia in the Striatum. 53
CuZn Superoxide dismutase increases intracellular calcium levels via phospholipase C-protein Kinase C pathway in SK-N-BE cells 53
Involvement of the Na+/Ca2+ exchanger isoform 1 (NCX1) in neuronal growth factor (NGF)-induced neuronal differentiation through Ca2+-dependent Akt phosphorylation 53
BHK cells transfected with NCX3 are more resistant to hypoxia followed by reoxygenation than those transfected with NCX1 and NCX2: Possible relationship with mitochondrial membrane potential 51
Glatiramer Acetate modulates ion channels expression and calcium homeostasis in B cell of patients with relapsing-remitting multiple sclerosis 50
Differentiation of monocytes into macrophages induces the upregulation of histamine H1 receptor. 49
Pharmacological characterization of the newly synthesized 5-amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide hydrochloride (BED) as a potent NCX3 inhibitor that worsens anoxic injury in cortical neurons, organotypic hippocampal cultures, and ischemic brain 47
Oleic acid promotes prostate cancer malignant phenotype via the G protein-coupled receptor FFA1/GPR40 47
Cigarette Smoke Condensate Causes a Decrease of the Gene Expression of Cu-Zn Superoxide Dismutase, Mn Superoxide Dismutase, Glutathione Peroxidase, Catalase, and Free Radical-Induced Cell Injury in SH-SY5Y Human Neuroblastoma Cells 46
The activation of Mucolipin TRP channel 1 (TRPML1) protects motor neurons from L-BMAA neurotoxicity by promoting autophagic clearance 46
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 45
BHK cells transfected with NCX3 are more resistant to hypoxia followed by reoxygenation than those transfected with NCX1 and NCX2: Possible relationship with mitochondrial membrane potential. 44
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions 44
Anoxia-induced NF-kappaB-dependent upregulation of NCX1 contributes to Ca2+ refilling into endoplasmic reticulum in cortical neurons 44
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 43
Galactosyl derivatives of L-arginine and D-arginine: synthesis, stability, cell permeation, and nitric oxide production in pituitary GH3 cells 43
Genetically modified mice as a strategy to unravel the role played by the na(+)/ca (2+) exchanger in brain ischemia and in spatial learning and memory deficits 43
D-Aspartate treatment attenuates myelin damage and stimulates myelin repair 43
Genetic Up-Regulation or Pharmacological Activation of the Na+/Ca2+ Exchanger 1 (NCX1) Enhances Hippocampal-Dependent Contextual and Spatial Learning and Memory 43
Evidence for a protective role played by Na+-Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats 42
The Na+/Ca2+ exchanger isoform 3 (NCX3) but not isoform 2 (NCX2) and 1 (NCX1) singly transfected in BHK cells plays a protective role in a model of in vitro hypoxia 42
Synthesis of cyclic N1-pentylinosine phosphate, a new structurally reduced cADPR analogue with calcium-mobilizing activity on PC12 cells 42
Preconditioning, induced by sub-toxic dose of the neurotoxin L-BMAA, delays ALS progression in mice and prevents Na+/Ca2+exchanger 3 downregulation 42
Human trisomic ipscs from down syndrome fibroblasts manifest mitochondrial alterations early during neuronal differentiation 42
The antiepileptic drug Leviracetam decreases the IP3-dependent [Ca2+] increase induced by ATP and BK in PC12 cells 41
The Anemonia sulcata Toxin BDS-I Protects Astrocytes Exposed to Aβ1–42 Oligomers by Restoring [Ca2+]i Transients and ER Ca2+ Signaling 41
Inhibition of depolarization-induced [3H]noradrenaline release from SH-SY5Y human neuroblastoma cells by some second-generation H(1) receptor antagonists through blockade of store-operated Ca(2+) channels (SOCs). 40
Resveratrol via sirtuin-1 downregulates RE1-silencing transcription factor (REST) expression preventing PCB-95-induced neuronal cell death 40
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 39
A1-42 fragment induces an up-regulation of NCX3 activity that prevents caspase-12 activation. 39
. Ab1-42 fragment induces an up-regulation of NCX3 activity that prevents caspase-12 activation. 39
Gliadin Peptides Induce Tissue Transglutaminase Activation and ER-Stress through Ca(2+) Mobilization in Caco-2 Cells. 39
Synthesis and Biological Evaluation of a New Structural Simplified Analogue of cADPR, a Calcium-Mobilizing Secondary Messenger Firstly Isolated from Sea Urchin Eggs 39
Involvement of PI3'-K, mitogen-activated protein kinase and protein kinase B in the up-regulation of the expression of nNOSalpha and nNOSbeta splicing variants induced by PRL-receptor activation in GH3 cells 38
NCX1 is a new rest target gene: role in cerebral ischemia 38
A New Cell-penetrating Peptide That Blocks the Autoinhibitory XIP Domain of NCX1 and Enhances Antiporter Activity 38
Prolonged NCX activation prevents SOD1 accumulation, reduces neuroinflammation, ameliorates motor behavior and prolongs survival in a ALS mouse model 37
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 36
Glutamate-independent calcium toxicity: Introduction. 36
Cu,Zn superoxide dismutase increases intracellular calcium levels via a phospholipase C-protein kinase C pathway in SK-N-BE neuroblastoma cells 36
Aβ1-42 fragment induces an up-regulation of NCX3 activity that prevents caspase-12 activation 36
Pharmacology of Amyotrophic Lateral Sclerosis Old Strategies and New Perspectives 36
Generation of an iPSC line (UNINAi001-A) from a girl with neonatal-onset epilepsy and non-syndromic intellectual disability carrying the homozygous KCNQ3 p.PHE534ILEfs*15 variant and of an iPSC line (UNINAi002-A) from a non-carrier, unaffected brother 36
Anti-tissue transglutaminase antibodies activate intracellular tissue transglutaminase by modulating cytosolic Ca2+ homeostasis. 35
Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage. 34
Effects of HIV-1 Tat protein on ion secretion and on cell proliferation in human intestinal epithelial cells 34
Histamine induces exocytosis and IL-6 production from human lung macrophages through interaction with H1 receptors 33
Expression and function of Na+/Ca2+ exchangers 1 and 3 in human macrophages and monocytes 33
Critical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons 33
SOD1 PREVENTS MOTOR NEURON DEATH INDUCED BY THE CYCAD NEUROTOXIN BETA-METHYLAMINO-L-ALANINE BY MODULATING PLASMA MEMBRANE TARGETS INVOLVED IN INTRACELLULAR Ca2+ HOMEOSTASIS 33
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions 32
Molecular pharmacology of the amiloride analog 3-amino-6-chloro-5-[(4-chloro-benzyl)amino]-n-[[(2,4-dimethylbenzyl)-amino]iminomethyl]-pyrazinecarboxamide (CB-DMB) as a pan inhibitor of the Na+-Ca2+ exchanger isoforms NCX1, NCX2, and NCX3 in stably transfected cells 32
Principi di farmacologia clinica, materna e fetale 32
Pioglitazone improves mitochondrial organization and bioenergetics in down syndrome cells 32
The Na+/Ca2+ exchangers in demyelinating diseases 32
Identification and characterization of the promoter and transcription factors regulating the expression of cerebral sodium/calcium exchanger 2 (NCX2) gene 32
Neuronal NOS activation during oxygen and glucose deprivation triggers cerebellar granule cell death in the later reoxygenation phase 31
TSH/cAMP up-regulate sarco/endoplasmic reticulum Ca2+-ATPases expression and activity in PC Cl3 thyroid cells 31
ORAI1/STIM1 INTERACTION INTERVENES IN STROKE AND IN NEUROPROTECTION INDUCED BY ISCHEMIC PRECONDITIONING THROUGH ER Ca2+ REFILLING 31
Inhibition of depolarization-induced [3H]noradrenaline release from SH-SY5Y human neuroblastoma cells by some second-generation H(1) receptor antagonists through blockade of store-operated Ca(2+) channels (SOCs). 30
Glutamate-independent calcium toxicity: introduction 30
Activation of pre-synaptic M-type K+ channels inhibits [3H]D-aspartate release by reducing Ca2+ entry through P/Q-type voltage-gated Ca2+ channels 30
null 30
A1-42 fragment induces an up-regulation of NCX3 activity that prevents caspase-12 activation. 30
Effects of D-aspartate on oligodendrocytes during differentiation, demyelination and remyelination processes 30
Nitric oxide stimulates NCX1 and NCX2 but inhibits NCX3 isoform by three distinct molecular determinants 29
ERK1/2, p38, and JNK regulate the expression and the activity of the three isoforms of the Na(+) /Ca(2+) exchanger, NCX1, NCX2, and NCX3, in neuronal PC12 cells. 29
Genetically modified mice to unravel physiological and pathophysiological roles played by NCX isoforms 29
Blockade of herg K+ channels by second-generation H1 receptor-antagonists may regulate [Ca2+]i oscillations in GH3 cells 28
Manidipine and Nitrendipine R and S enantiomers block voltage-gated Ca2+ channel (VGCC) with different kinetic in GH3 cell 28
Human macrophages and monocytes express functional na(+)/ca (2+) exchangers 1 and 3 28
The modulation of intracellular Ca2+ homeostasis is involved in SOD1 and ApoSOD1-induced neuroprotection of motor neurons exposed to beta-methylamino-L-alanine 28
The antiepileptic drug levetiracetam decreases the inositol 1,4,5-trisphosphate-dependent [Ca2+]I increase induced by ATP and bradykinin in PC12 cells 28
null 27
Effects of manidipine and nitrendipine enantiomers on the plateau phase of K+-induced intracellular Ca2+ increase in GH3 cells. 27
Nitric oxide induces [Ca2+]i oscillations in pituitary GH3 cells: involvement of IDR and ERG K+ currents 27
A new concept: Aβ1-42 generates a hyperfunctional proteolytic NCX3 fragment that delays caspase-12 activation and neuronal death 27
Polychlorinated Biphenyls Induce Mitochondrial Dysfunction in SH-SY5Y Neuroblastoma Cells 27
Calcium Dyshomeostasis and Lysosomal Ca2+ Dysfunction in Amyotrophic Lateral Sclerosis 27
The antioxidant activity of limonene counteracts neurotoxicity triggered byaβ1-42 oligomers in primary cortical neurons 27
Probing the Ca2+ mobilizing properties on primary cortical neurons of a new stable cADPR mimic 27
SARS-CoV-2 Spike Protein Activates Human Lung Macrophages 26
The antiepileptic drug levetiracetam decreases the inositol 1,4,5-trisphosphate-dependent [Ca2+]I increase induced by ATP and bradykinin in PC12 cells. 26
Involvement of PI3'-K, mitogen-activated protein kinase and protein kinase B in the up-regulation of the expression of nNOSalpha and nNOSbeta splicing variants induced by PRL-receptor activation in GH3 cells. 26
'Janus face' of nitric oxide action on plasma membrane and intracellular ionic channels. 26
New Insights into the Structure-Activity Relationship and Neuroprotective Profile of Benzodiazepinone Derivatives of Neurounina-1 as Modulators of the Na+/Ca2+Exchanger Isoforms 26
Totale 4.425
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Categoria #
all - tutte 20.419
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 20.419
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201973 0 0 0 0 0 0 0 0 0 23 9 41
2019/2020691 204 15 49 26 66 12 47 16 16 48 86 106
2020/2021657 24 53 70 69 70 79 52 13 85 18 68 56
2021/20221.070 26 8 13 13 18 28 13 55 119 97 323 357
2022/20231.419 187 130 48 112 156 157 19 116 201 176 75 42
2023/20241.025 38 148 101 104 60 89 24 399 23 39 0 0
Totale 5.802