IRIS
SECONDO, AGNESE
 Distribuzione geografica
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Continente #
EU - Europa 4.940
NA - Nord America 3.768
AS - Asia 2.345
SA - Sud America 400
AF - Africa 107
Continente sconosciuto - Info sul continente non disponibili 2
Totale 11.562
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Nazione #
US - Stati Uniti d'America 3.652
RU - Federazione Russa 2.051
IT - Italia 1.322
SG - Singapore 1.161
CN - Cina 488
HK - Hong Kong 455
DE - Germania 438
BR - Brasile 359
UA - Ucraina 257
FI - Finlandia 240
NL - Olanda 199
IE - Irlanda 120
GB - Regno Unito 102
CA - Canada 90
FR - Francia 82
CI - Costa d'Avorio 75
VN - Vietnam 57
IN - India 40
SE - Svezia 40
KR - Corea 21
ES - Italia 19
MX - Messico 18
ZA - Sudafrica 18
JP - Giappone 17
AR - Argentina 16
TR - Turchia 16
BD - Bangladesh 15
BE - Belgio 14
CH - Svizzera 13
PL - Polonia 12
IR - Iran 11
AT - Austria 10
IQ - Iraq 10
CL - Cile 8
IL - Israele 8
EC - Ecuador 7
SA - Arabia Saudita 7
PK - Pakistan 6
KE - Kenya 5
ID - Indonesia 4
LT - Lituania 4
MA - Marocco 4
PH - Filippine 4
UZ - Uzbekistan 4
CO - Colombia 3
CZ - Repubblica Ceca 3
KG - Kirghizistan 3
OM - Oman 3
PE - Perù 3
AE - Emirati Arabi Uniti 2
AM - Armenia 2
BG - Bulgaria 2
BY - Bielorussia 2
EG - Egitto 2
EU - Europa 2
GR - Grecia 2
NO - Norvegia 2
NP - Nepal 2
PA - Panama 2
PT - Portogallo 2
TH - Thailandia 2
TW - Taiwan 2
VE - Venezuela 2
AZ - Azerbaigian 1
CR - Costa Rica 1
DK - Danimarca 1
EE - Estonia 1
ET - Etiopia 1
GT - Guatemala 1
GY - Guiana 1
HN - Honduras 1
HU - Ungheria 1
JM - Giamaica 1
JO - Giordania 1
KW - Kuwait 1
KZ - Kazakistan 1
ML - Mali 1
PS - Palestinian Territory 1
RO - Romania 1
SN - Senegal 1
SV - El Salvador 1
TT - Trinidad e Tobago 1
UY - Uruguay 1
Totale 11.562
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Città #
Singapore 772
Chandler 594
Moscow 513
Hong Kong 438
Ashburn 428
Jacksonville 234
Santa Clara 204
Napoli 188
Naples 173
Amsterdam 163
Millbury 153
Princeton 124
Nanjing 108
Beijing 107
Boston 101
Munich 98
Ottawa 66
Wilmington 63
Helsinki 58
Rome 58
Turku 53
Seattle 45
Hefei 42
Formia 41
Dong Ket 40
Milan 40
Des Moines 39
Lawrence 38
Dearborn 37
Falkenstein 34
Frankfurt am Main 31
São Paulo 31
Nanchang 28
Nuremberg 22
Norwalk 21
Salerno 20
Los Angeles 18
Hebei 17
Shenyang 17
Changsha 16
Seoul 16
Caserta 15
Kronberg 15
Portici 15
Tianjin 15
Toronto 15
Dublin 14
Houston 14
Jiaxing 14
Pavullo Nel Frignano 13
Woodbridge 13
London 12
New York 12
Washington 12
Bari 11
Falls Church 11
Parma 11
Pune 11
The Dalles 11
Abano Terme 10
Brooklyn 10
Dallas 10
Lappeenranta 10
Boardman 9
Sudbury 9
Brussels 8
Catania 8
Ho Chi Minh City 8
Redwood City 8
Tokyo 8
Turin 8
Augusta 7
Belo Horizonte 7
Castel Campagnano 7
Chicago 7
Düsseldorf 7
Genoa 7
Guangzhou 7
Highland Park 7
Mexico City 7
Palermo 7
San Francisco 7
Valladolid 7
Baghdad 6
Bologna 6
Brasília 6
Cambridge 6
Fairfield 6
Kunming 6
Menlo Park 6
Montreal 6
Ribeirão Preto 6
Rio de Janeiro 6
Rizziconi 6
Warsaw 6
Florence 5
Manchester 5
Mountain View 5
Perugia 5
Phoenix 5
Totale 5.810
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Nome #
Studio del ruolo della proteina AKAP121 nel controllo della funzionalità mitocondriale in modelli cellulari di anossia/reossigenazione come bersaglio per lo sviluppo di molecole di potenziale impiego terapeutico nell'ischemia cerebrale 386
7-nitro-5-fenil-1(pirrolidin-1-ilmetil)-1H-benzo[e][1,4] diazepin-2(3H)-one ed altri composti derivati delle benzodiazepine 343
Profarmaci dell’arginina con elevata attività terapeutica 202
The pharmacological activation of Mucolipin TRP channel 1 (TRPML1) protects motor neurons exposed to the cycad neurotoxin L-BMAA by promoting autophagic clearance 148
Na+/Ca2+ exchanger 1 on nuclear envelope controls PTEN/Akt pathway via nucleoplasmic Ca2+ regulation during neuronal differentiation 109
ncx1, ncx2, and ncx3 gene product expression and function in neuronal anoxia and brain ischemia. 101
Glatiramer Acetate modulates ion channels expression and calcium homeostasis in B cell of patients with relapsing-remitting multiple sclerosis 100
The functional coupling between endoplasmic reticulum and lysosomes for intracellular Ca2+ handling is disrupted in brain ischemia 99
Oleic acid promotes prostate cancer malignant phenotype via the G protein-coupled receptor FFA1/GPR40 97
Human lung-resident macrophages express CB1 and CB2 receptors whose activation inhibits the release of angiogenic and lymphangiogenic factors. STAIANO and LOFFREDO are CO-FIRST AUTHORS. 96
Involvement of the Na+/Ca2+ exchanger isoform 1 (NCX1) in neuronal growth factor (NGF)-induced neuronal differentiation through Ca2+-dependent Akt phosphorylation 95
A critical role for the potassium-dependent sodium-calcium exchanger NCKX2 in protection against focal ischemic brain damage. 93
Pharmacological characterization of the newly synthesized 5-amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide hydrochloride (BED) as a potent NCX3 inhibitor that worsens anoxic injury in cortical neurons, organotypic hippocampal cultures, and ischemic brain 92
BHK cells transfected with NCX3 are more resistant to hypoxia followed by reoxygenation than those transfected with NCX1 and NCX2: Possible relationship with mitochondrial membrane potential 91
ApoSOD1 lacking dismutase activity neuroprotects motor neurons exposed to beta-methylamino-L-alanine through the Ca(2+)/Akt/ERK1/2 prosurvival pathway 90
SARS-CoV-2 Spike Protein Activates Human Lung Macrophages 88
NCX1 Exchanger Cooperates with Calretinin to Confer Preconditioning-Induced Tolerance Against Cerebral Ischemia in the Striatum. 88
Preconditioning, induced by sub-toxic dose of the neurotoxin L-BMAA, delays ALS progression in mice and prevents Na+/Ca2+exchanger 3 downregulation 88
Involvement of the nitric oxide/protein kinase G pathway in polychlorinated biphenyl-induced cell death in SH-SY 5Y neuroblastoma cells 87
Neuronal NCX1 overexpression induces stroke resistance while knockout induces vulnerability via Akt 87
Genetically modified mice as a strategy to unravel the role played by the na(+)/ca (2+) exchanger in brain ischemia and in spatial learning and memory deficits 86
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 84
CuZn Superoxide dismutase increases intracellular calcium levels via phospholipase C-protein Kinase C pathway in SK-N-BE cells 84
Zinc inhibits calcium-mediated and nitric oxide-mediated ion secretion in human enterocytes 84
The activation of Mucolipin TRP channel 1 (TRPML1) protects motor neurons from L-BMAA neurotoxicity by promoting autophagic clearance 83
Involvement of PI3'-K, mitogen-activated protein kinase and protein kinase B in the up-regulation of the expression of nNOSalpha and nNOSbeta splicing variants induced by PRL-receptor activation in GH3 cells 80
Human trisomic ipscs from down syndrome fibroblasts manifest mitochondrial alterations early during neuronal differentiation 80
Cigarette Smoke Condensate Causes a Decrease of the Gene Expression of Cu-Zn Superoxide Dismutase, Mn Superoxide Dismutase, Glutathione Peroxidase, Catalase, and Free Radical-Induced Cell Injury in SH-SY5Y Human Neuroblastoma Cells 79
7-nitro-5-phenyl-1-(pyrrolidin-1-ylmethyl)-1H-benzo[E][1,4]diazepin-2(3H)-one and other benzodiazepine derivatives 79
A New Cell-penetrating Peptide That Blocks the Autoinhibitory XIP Domain of NCX1 and Enhances Antiporter Activity 79
Inhibition of depolarization-induced [3H]noradrenaline release from SH-SY5Y human neuroblastoma cells by some second-generation H(1) receptor antagonists through blockade of store-operated Ca(2+) channels (SOCs). 78
NCX1 is a new rest target gene: role in cerebral ischemia 78
D-Aspartate treatment attenuates myelin damage and stimulates myelin repair 78
Genetic Up-Regulation or Pharmacological Activation of the Na+/Ca2+ Exchanger 1 (NCX1) Enhances Hippocampal-Dependent Contextual and Spatial Learning and Memory 78
TSH/cAMP up-regulate sarco/endoplasmic reticulum Ca2+-ATPases expression and activity in PC Cl3 thyroid cells 77
. Ab1-42 fragment induces an up-regulation of NCX3 activity that prevents caspase-12 activation. 77
Pioglitazone improves mitochondrial organization and bioenergetics in down syndrome cells 77
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions 76
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 76
Synthesis of cyclic N1-pentylinosine phosphate, a new structurally reduced cADPR analogue with calcium-mobilizing activity on PC12 cells 76
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 75
Anoxia-induced NF-kappaB-dependent upregulation of NCX1 contributes to Ca2+ refilling into endoplasmic reticulum in cortical neurons 75
The Anemonia sulcata Toxin BDS-I Protects Astrocytes Exposed to Aβ1–42 Oligomers by Restoring [Ca2+]i Transients and ER Ca2+ Signaling 75
Prolonged NCX activation prevents SOD1 accumulation, reduces neuroinflammation, ameliorates motor behavior and prolongs survival in a ALS mouse model 75
Evidence for a protective role played by Na+-Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats 74
Galactosyl derivatives of L-arginine and D-arginine: synthesis, stability, cell permeation, and nitric oxide production in pituitary GH3 cells 74
The Na+/Ca2+ exchanger isoform 3 (NCX3) but not isoform 2 (NCX2) and 1 (NCX1) singly transfected in BHK cells plays a protective role in a model of in vitro hypoxia 74
Molecular pharmacology of the amiloride analog 3-amino-6-chloro-5-[(4-chloro-benzyl)amino]-n-[[(2,4-dimethylbenzyl)-amino]iminomethyl]-pyrazinecarboxamide (CB-DMB) as a pan inhibitor of the Na+-Ca2+ exchanger isoforms NCX1, NCX2, and NCX3 in stably transfected cells 74
BHK cells transfected with NCX3 are more resistant to hypoxia followed by reoxygenation than those transfected with NCX1 and NCX2: Possible relationship with mitochondrial membrane potential. 73
Principi di farmacologia clinica, materna e fetale 73
Aβ1-42 fragment induces an up-regulation of NCX3 activity that prevents caspase-12 activation 73
Resveratrol via sirtuin-1 downregulates RE1-silencing transcription factor (REST) expression preventing PCB-95-induced neuronal cell death 73
Identification and characterization of the promoter and transcription factors regulating the expression of cerebral sodium/calcium exchanger 2 (NCX2) gene 72
The antioxidant activity of limonene counteracts neurotoxicity triggered byaβ1-42 oligomers in primary cortical neurons 72
Inhibition of depolarization-induced [3H]noradrenaline release from SH-SY5Y human neuroblastoma cells by some second-generation H(1) receptor antagonists through blockade of store-operated Ca(2+) channels (SOCs). 71
Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage. 71
Pharmacology of Amyotrophic Lateral Sclerosis Old Strategies and New Perspectives 71
Genetically modified mice to unravel physiological and pathophysiological roles played by NCX isoforms 71
The Na+/Ca2+ exchangers in demyelinating diseases 71
SOD1 PREVENTS MOTOR NEURON DEATH INDUCED BY THE CYCAD NEUROTOXIN BETA-METHYLAMINO-L-ALANINE BY MODULATING PLASMA MEMBRANE TARGETS INVOLVED IN INTRACELLULAR Ca2+ HOMEOSTASIS 70
Calcium Dyshomeostasis and Lysosomal Ca2+ Dysfunction in Amyotrophic Lateral Sclerosis 70
Effects of HIV-1 Tat protein on ion secretion and on cell proliferation in human intestinal epithelial cells 69
Generation of an iPSC line (UNINAi001-A) from a girl with neonatal-onset epilepsy and non-syndromic intellectual disability carrying the homozygous KCNQ3 p.PHE534ILEfs*15 variant and of an iPSC line (UNINAi002-A) from a non-carrier, unaffected brother 69
Na+/Ca2+ exchanger isoform 1 takes part to the Ca2+-related prosurvival pathway of SOD1 in primary motor neurons exposed to beta-methylamino-l-alanine 69
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 66
Pharmacological blockade of ERG K+ channels and Ca2+ influx through store-operated channels exerts opposite effects on intracellular Ca2+ oscillations in pituitary GH3 cells 66
Nitric oxide stimulates NCX1 and NCX2 but inhibits NCX3 isoform by three distinct molecular determinants 66
Synthesis and Biological Evaluation of a New Structural Simplified Analogue of cADPR, a Calcium-Mobilizing Secondary Messenger Firstly Isolated from Sea Urchin Eggs 66
Effects of D-aspartate on oligodendrocytes during differentiation, demyelination and remyelination processes 66
Probing the Ca2+ mobilizing properties on primary cortical neurons of a new stable cADPR mimic 66
Exploring the Therapeutic Potential of Phytochemicals in Alzheimer's Disease: Focus on Polyphenols and Monoterpenes 66
Differentiation of monocytes into macrophages induces the upregulation of histamine H1 receptor. 65
Effects of manidipine and nitrendipine enantiomers on the plateau phase of K+-induced intracellular Ca2+ increase in GH3 cells. 65
Gliadin Peptides Induce Tissue Transglutaminase Activation and ER-Stress through Ca(2+) Mobilization in Caco-2 Cells. 65
The modulation of intracellular Ca2+ homeostasis is involved in SOD1 and ApoSOD1-induced neuroprotection of motor neurons exposed to beta-methylamino-L-alanine 65
ORAI1/STIM1 INTERACTION INTERVENES IN STROKE AND IN NEUROPROTECTION INDUCED BY ISCHEMIC PRECONDITIONING THROUGH ER Ca2+ REFILLING 65
Na+/Ca2+ exchanger in Na+ efflux-Ca2+ influx mode of operation exerts a neuroprotective role in cellular models of in vitro anoxia and in vivo cerebral ischemia. 64
Cu,Zn superoxide dismutase increases intracellular calcium levels via a phospholipase C-protein kinase C pathway in SK-N-BE neuroblastoma cells 64
Endoplasmic reticulum refilling and mitochondrial calcium extrusion promoted in neurons by NCX1 and NCX3 in ischemic preconditioning are determinant for neuroprotection 64
Anti-tissue transglutaminase antibodies activate intracellular tissue transglutaminase by modulating cytosolic Ca2+ homeostasis. 64
Increased KV2.1 Channel Clustering Underlies the Reduction of Delayed Rectifier K+ Currents in Hippocampal Neurons of the Tg2576 Alzheimer's Disease Mouse 63
Modulation of ion channels by reactive oxygen and nitrogen species: a pathophysiological role in brain aging? 63
Expression and function of Na+/Ca2+ exchangers 1 and 3 in human macrophages and monocytes 63
A1-42 fragment induces an up-regulation of NCX3 activity that prevents caspase-12 activation. 63
ORAI1/STIM1 Interaction Intervenes in Stroke and in Neuroprotection Induced by Ischemic Preconditioning Through Store-Operated Calcium Entry 63
The Na+/Ca2+ Exchanger 3 Is Functionally Coupled With the NaV1.6 Voltage-Gated Channel and Promotes an Endoplasmic Reticulum Ca2+ Refilling in a Transgenic Model of Alzheimer’s Disease 62
Activation of pre-synaptic M-type K+ channels inhibits [3H]D-aspartate release by reducing Ca2+ entry through P/Q-type voltage-gated Ca2+ channels 61
ERK1/2, p38, and JNK regulate the expression and the activity of the three isoforms of the Na(+) /Ca(2+) exchanger, NCX1, NCX2, and NCX3, in neuronal PC12 cells. 61
Neurounina-1, a Novel Compound that Increases Na+/Ca2+ Exchanger Activity, Effectively Protects Against Stroke Damage 61
'Janus face' of nitric oxide action on plasma membrane and intracellular ionic channels. 60
Neuronal NOS activation during oxygen and glucose deprivation triggers cerebellar granule cell death in the later reoxygenation phase 60
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions 60
Size-based effects of anthropogenic ultrafine particles on activation of human lung macrophages 59
Involvement of PI3'-K, mitogen-activated protein kinase and protein kinase B in the up-regulation of the expression of nNOSalpha and nNOSbeta splicing variants induced by PRL-receptor activation in GH3 cells. 59
pharmacological blockade of ERG K+ channels and Ca2+ influx through store-operated channels exerts opposite effects on intracellular Ca2+ oscillations in pituitary gh3 cells 59
The antiepileptic drug Leviracetam decreases the IP3-dependent [Ca2+] increase induced by ATP and BK in PC12 cells 59
NCX1 Expression and Functional Activity Increase in Microglia Invading the Infarct Core 59
Critical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons 59
Arginine prodrugs with high therapeutic activity 59
Glutamate-independent calcium toxicity: introduction 58
Totale 8.157
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Categoria #
all - tutte 45.179
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 45.179
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021657 24 53 70 69 70 79 52 13 85 18 68 56
2021/20221.070 26 8 13 13 18 28 13 55 119 97 323 357
2022/20231.411 187 130 48 111 154 156 19 115 200 174 75 42
2023/20241.265 38 147 100 104 59 89 24 399 23 39 148 95
2024/20255.538 237 274 47 90 160 328 586 373 332 535 2.114 462
2025/2026300 300 0 0 0 0 0 0 0 0 0 0 0
Totale 11.872