IRIS
PAGANO, BRUNO
 Distribuzione geografica
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Continente #
NA - Nord America 3.059
EU - Europa 2.505
AS - Asia 1.644
SA - Sud America 85
AF - Africa 76
OC - Oceania 3
Continente sconosciuto - Info sul continente non disponibili 1
Totale 7.373
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Nazione #
US - Stati Uniti d'America 2.988
IT - Italia 1.130
SG - Singapore 842
CN - Cina 392
HK - Hong Kong 330
NL - Olanda 280
RU - Federazione Russa 253
IE - Irlanda 170
FI - Finlandia 159
DE - Germania 154
BR - Brasile 77
SE - Svezia 77
UA - Ucraina 72
CI - Costa d'Avorio 68
CA - Canada 66
GB - Regno Unito 60
FR - Francia 38
IN - India 24
BE - Belgio 22
CZ - Repubblica Ceca 20
OM - Oman 15
GR - Grecia 12
ES - Italia 9
SI - Slovenia 8
AT - Austria 7
LT - Lituania 7
KR - Corea 6
UZ - Uzbekistan 6
TR - Turchia 5
ZA - Sudafrica 5
IR - Iran 4
PT - Portogallo 4
RO - Romania 4
BG - Bulgaria 3
CH - Svizzera 3
MX - Messico 3
PK - Pakistan 3
AR - Argentina 2
AU - Australia 2
DK - Danimarca 2
EC - Ecuador 2
JP - Giappone 2
PL - Polonia 2
PY - Paraguay 2
TW - Taiwan 2
VN - Vietnam 2
AE - Emirati Arabi Uniti 1
AL - Albania 1
BD - Bangladesh 1
BS - Bahamas 1
CY - Cipro 1
EE - Estonia 1
EU - Europa 1
ID - Indonesia 1
IM - Isola di Man 1
IQ - Iraq 1
IS - Islanda 1
JO - Giordania 1
KE - Kenya 1
LU - Lussemburgo 1
MA - Marocco 1
MC - Monaco 1
MK - Macedonia 1
MO - Macao, regione amministrativa speciale della Cina 1
MY - Malesia 1
NG - Nigeria 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PA - Panama 1
PE - Perù 1
SA - Arabia Saudita 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
TM - Turkmenistan 1
UY - Uruguay 1
Totale 7.373
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Città #
Chandler 676
Singapore 493
Hong Kong 330
Naples 313
Amsterdam 250
Santa Clara 196
Millbury 157
Napoli 153
Ashburn 141
Princeton 117
Nanjing 105
Jacksonville 99
Beijing 95
Boston 80
Des Moines 71
Ottawa 58
Wilmington 53
Helsinki 40
Rome 36
Lawrence 34
Milan 33
Dearborn 32
Salerno 31
Nanchang 30
Shenyang 27
Seattle 24
Houston 21
Jiaxing 21
Woodbridge 20
Falkenstein 19
Changsha 18
Hebei 18
Brussels 17
Redwood City 17
Letovice 15
Boardman 14
Kronberg 13
Moscow 13
Nuremberg 13
Tianjin 13
Los Angeles 11
Norwalk 11
Thessaloniki 11
Augusta 10
Florence 10
London 10
The Dalles 10
Torre del Greco 10
Bologna 8
Dublin 8
Kunming 8
Ljubljana 8
Paris 8
Cagliari 7
Caserta 7
Council Bluffs 7
Scafati 7
São Paulo 7
Ann Arbor 6
Frankfurt am Main 6
Madrid 6
Quarto 6
Stockholm 6
Tashkent 6
Toronto 6
Trieste 6
Turin 6
Verona 6
Caivano 5
Fairfield 5
Fucecchio 5
Marigliano 5
Mountain View 5
Padova 5
Rio Grande 5
Altamura 4
Canterbury 4
Centro 4
Changchun 4
Chuncheon 4
Como 4
Cosenza 4
Dallas 4
Falls Church 4
Fermo 4
Gurgaon 4
Orange 4
Palermo 4
Pavia 4
Perugia 4
Pune 4
Selargius 4
Seregno 4
Solofra 4
Spoltore 4
West Lafayette 4
Bari 3
Brescia 3
Cambridge 3
Campo Grande 3
Totale 4.255
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Nome #
Nuovi ligandi per G-quadruplex: un approccio chimico-fisico nella terapia anti-cancro 126
1H NMR-based metabolomics study on follicular fluid from patients with Polycystic Ovary Syndrome 125
Characterisation of the dynamic interactions between complex N-glycans and human CD22 110
Bio-Inspired Dual-Selective BCL-2/c-MYC G-Quadruplex Binders: Design, Synthesis, and Anticancer Activity of Drug-like Imidazo[2,1-i]purine Derivatives 101
Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes 93
Aptameri formanti G-quadruplex per la terapia delle malattie da prioni 83
A fast route for the synthesis of tetrazolyl oximes by a novel multicomponent reaction between Z-chlorooximes, isocyanides and trimethylsilyl azide 83
Common G-quadruplex binding agents found to interact with i-motif-forming DNA: Unexpected multi-target-directed compounds 82
Conformational stability and DNA binding energetics of the rat thyroid transcription factor 1 homeodomain 71
Targeting the BCL2 Gene Promoter G-Quadruplex with a New Class of Furopyridazinone-Based Molecules 71
Shooting for selective drug-like DNA G-quadruplex binders 70
Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: a new opportunity in the targeting of G-rich DNA structures? 70
On the binding of naphthalene diimides to a human telomeric G-quadruplex multimer model 70
Identification of novel interactors of human telomeric G-quadruplex DNA 69
Cyclodextrin-assisted assembly of PEGylated polyester nanoparticles decorated with folate 69
Characterization of monovarietal extra virgin olive oils from the province of Béjaïa (Algeria) 69
Conformational stability and DNA binding energetics of the rat thyroid transcription factor 1 homeodomain 68
Fluorescence enhancement in G-quadruplex folding: synthesis, structure and stability of a novel dansyl-tagged, conjugated TBA 67
Tetramolecular G-quadruplex Assembly: Effects of Polarity Site Inversions 67
Targeting of telomeric repeat-containing RNA G-quadruplexes: From screening to biophysical and biological characterization of a new hit compound 67
Insights into telomeric G-quadruplex DNA recognition by HMGB1 protein 66
Binding of distamycin and analogues to quadruplex structures 65
NMR Assignment of N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide Seized as Herbal Incense for the First Time in Italy 64
Monohydrazone Based G-Quadruplex Selective Ligands Induce DNA Damage and Genome Instability in Human Cancer Cells 64
Design, synthesis, biophysical and biological studies on trisubstituted naphthalimides as G-Quadruplex ligands 63
Structural and conformational requisites in DNA quadruplex groove binding: Another piece to the puzzle 63
Thermodynamic analysis of quadruplex DNA-drug interaction 62
Identification of an acetal derivative of the piperonyl methyl ketone in tablets seized for suspected drug trafficking 62
A new fluorescent TBA for early detection of thrombin: A biophysical study 62
Analysis of quadruplex ligands by displacement isothermal titration calorimetry 62
G-quadruplexes in cancer-related gene promoters: from identification to therapeutic targeting 61
Aspetti dell’interazione tra la distamicina-A e la quadruplex [d(TGGGGT)]4 61
Tailoring a lead-like compound targeting multiple G-quadruplex structures 61
Targeting the Human Telomeric G-Quadruplex Through Virtual Screening Calculations 60
Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-7 60
Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d(TGGGGT)]4 59
G-Quadruplex Binders Induce Immunogenic Cell Death Markers in Aggressive Breast Cancer Cells 59
Thermodynamics and kinetics of PNA-DNA quadruplex-forming chimeras 57
Structural revision of clusianone and 7-epi-clusianone and anti-HIV activity of polyisoprenylated benzophenones 56
Binding of TMPyP4 to higher-order telomeric quadruplexes: a biophysical study 55
Fluorescence enhancement in G-quadruplex folding: Synthesis, structure and stability of a novel dansyl-tagged, conjugated TBA 54
Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations 54
Conformational plasticity of DNA secondary structures: probing the conversion between i-motif and hairpin species by circular dichroism and ultraviolet resonance Raman spectroscopies 54
Effects of Sequence and Base Composition on the CD and TDS Profiles of i-DNA 54
Interfering with the Tumor-Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors 54
Shooting for selective druglike G-quadruplex binders: evidence for telomeric DNA damage and tumor cell death 53
A novel dansyl-labelled TBA15 analog showing fluorescence enhancement upon G-quadruplex formation for early detection of thrombin 53
How are thermodynamically stable G-quadruplex-duplex hybrids? 53
Impact of phytosterols on liver and distal colon metabolome in experimental murine colitis model: an explorative study 53
Method for the preparation of a low unspecific binding-support for affinity chromatography and/or on-line synthesis of oligonucleotides 53
Energetics of quadruplex-drug recognition in anticancer therapy 52
Energetics of Biomolecular Interactions 52
Energetic Aspects of the recognition between G-Quadruplex structures and ligands 52
Structural and conformational requisites in DNA quadruplex groove binding: Another piece to the puzzle 52
Binding and stability of G-quadruplexes: Insights from biocalorimetry 52
A New DNA Structural Motif: The G-Triplex 52
Toward the Development of Specific G-Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives 52
Lead Discovery of Dual G-Quadruplex Stabilizers and Poly(ADP-ribose) Polymerases (PARPs) Inhibitors: A New Avenue in Anticancer Treatment 52
Stability and binding properties of a modified Thrombin binding aptamer 51
Controlled Pore Glass-based oligonucleotide affinity support: towards High Throughput Screening methods for the identification of conformation-selective G-quadruplex ligands 51
Discovery of 2,3-Diaminoindole Derivatives as a Novel Class of NOD Antagonists 50
Interaction of azatrux with the G-quadruplex parallel fold: biophysical insight into the binding propietes to address drug design 50
Synthesis and characterization of bis-triazolyl-pyridine derivatives as noncanonical DNA-interacting compounds 50
Thermodynamic analysis of Quadruplex DNA-drugs interaction 49
Biophysical study of the human telomeric quadruplexes-drugs interaction: a good starting point for anti cancer agents 49
HMGB1 binds to the KRAS promoter G-quadruplex: A new player in oncogene transcriptional regulation? 49
A novel β-hairpin peptide derived from the ARC repressor selectively interacts with the major groove of B-DNA 49
State-of-the-art methodologies for the discovery and characterization of DNA G-Quadruplex binders 48
Shooting for selective drug-like G-quadruplex binders: Evidence for telomeric DNA damage and tumor cell death 48
Shooting for Selective Drug-Like DNA G-Quadruplex Binders 48
Binding of Harmine Derivatives to DNA: A Spectroscopic Investigation 48
Stabilità termodinamica del multimero del telomero umano ed energetica dell’interazione con la porfirina cationica 47
Looking for efficient G-quadruplex ligands: Evidence for selective stabilizing properties and telomere damage by drug-like molecules 47
Metodo per la preparazione di un supporto a basso legame aspecifico per cromatografia di affinità e/o sintesi diretta di oligonucleotidi 47
Structural and Conformational Requisites in DNA Quadruplex Groove Binding 46
Interaction between prion protein and G-quadruplex-forming nucleic acids: a biophysical study 46
Unveiling the interaction between DNA G-quadruplexes and RG-rich peptides 46
Unlocking the potential of protein-derived peptides to target G-quadruplex DNA: from recognition to anticancer activity 45
Stability and binding properties of a modified Thrombin binding aptamer 45
Analisi termodinamica dell’interazione tra ligandi e quadruple del DNA telomerico umano 45
Selective Binding of Distamycin A Derivative to G-Quadruolex Structure [d(TGGGGT)]4 45
Stability and binding properties of a modified thrombin binding aptamer 44
Structural insight into the hTERT intron 6 sequence d(GGGGTGAAAGGGG) from 1H-NMR study 44
Biophysical characterization of interaction between prion and G-quadruplex forming aptamers 44
Targeting multiple G-quadruplex–forming DNA sequences: Design, biophysical and biological evaluations of indolo-naphthyridine scaffold derivatives 44
Toward G-Quadruplex-Based Anticancer Agents: Biophysical and Biological Studies of Novel AS1411 Derivatives 44
Targeting DNA quadruplexes with distamycin A and its derivatives: An ITC and NMR study 43
Biophysical properties of quadruplexes formed by PNA-DNA chimeras 43
Cross-talk between prion protein and quadruplex-forming nucleic acids: a dynamic complex formation 43
Bis-indole derivatives with antitumor activity turn out to be specific ligands of human telomeric G-quadruplex 43
Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics 41
Noncanonical DNA secondary structures as drug targets: The prospect of the i-motif 41
Assessing the influence of pH and cationic strength on i-motif DNA structure 41
BioCalorimetry of G-Quadruplex Structures 40
Application of "magnetic tongue" to the sensory evaluation of extra virgin olive oil 40
New ligands for DNA telomeric G-quadruplexes: a thermodynamic approach towards anti-cancer therapy 40
The triazatruxene derivative azatrux binds to the parallel form of the human telomeric G-quadruplex under molecular crowding conditions: biophysical and molecular modeling studies 39
Exploring the chemical space of G-quadruplex binders: Discovery of a novel chemotype targeting the human telomeric sequence 39
Interaction of azatrux to human telomeric DNA: A thermodynamic analysis 38
Targeting cKit87up quadruplex structure with short PNA sequences: a physico-chemical approach 38
Totale 5.692
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Categoria #
all - tutte 33.386
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 33.386
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020160 0 0 0 0 0 0 0 0 0 38 67 55
2020/2021467 27 21 33 25 52 97 47 34 50 24 45 12
2021/2022880 24 3 7 9 22 25 18 43 184 63 120 362
2022/20231.633 169 121 42 197 141 186 12 165 226 237 108 29
2023/2024926 41 144 179 61 38 54 23 143 23 15 144 61
2024/20252.299 234 278 38 68 137 271 451 305 313 204 0 0
Totale 7.613