IRIS
PAGANO, BRUNO
 Distribuzione geografica
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Continente #
NA - Nord America 2.592
EU - Europa 1.817
AS - Asia 411
AF - Africa 69
SA - Sud America 10
OC - Oceania 2
Continente sconosciuto - Info sul continente non disponibili 1
Totale 4.902
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Nazione #
US - Stati Uniti d'America 2.532
IT - Italia 862
CN - Cina 353
NL - Olanda 256
IE - Irlanda 170
FI - Finlandia 122
DE - Germania 107
SE - Svezia 76
UA - Ucraina 69
CI - Costa d'Avorio 67
CA - Canada 59
GB - Regno Unito 50
FR - Francia 28
CZ - Repubblica Ceca 20
IN - India 20
OM - Oman 15
BR - Brasile 9
RU - Federazione Russa 8
SI - Slovenia 8
BE - Belgio 7
ES - Italia 7
SG - Singapore 5
IR - Iran 4
RO - Romania 4
CH - Svizzera 3
PT - Portogallo 3
BG - Bulgaria 2
DK - Danimarca 2
JP - Giappone 2
KR - Corea 2
PL - Polonia 2
TR - Turchia 2
TW - Taiwan 2
AL - Albania 1
AT - Austria 1
AU - Australia 1
BS - Bahamas 1
CY - Cipro 1
EU - Europa 1
GR - Grecia 1
ID - Indonesia 1
IM - Isola di Man 1
IS - Islanda 1
LT - Lituania 1
LU - Lussemburgo 1
MA - Marocco 1
MC - Monaco 1
MK - Macedonia 1
MO - Macao, regione amministrativa speciale della Cina 1
MY - Malesia 1
NG - Nigeria 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PY - Paraguay 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
VN - Vietnam 1
Totale 4.902
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Città #
Chandler 676
Amsterdam 245
Naples 177
Millbury 158
Napoli 153
Ashburn 122
Princeton 118
Nanjing 105
Jacksonville 100
Beijing 88
Boston 81
Des Moines 71
Ottawa 57
Wilmington 54
Lawrence 34
Dearborn 32
Nanchang 31
Salerno 31
Shenyang 27
Houston 21
Jiaxing 21
Milan 21
Woodbridge 20
Rome 19
Hebei 18
Changsha 17
Redwood City 17
Letovice 15
Boardman 14
Kronberg 13
Tianjin 13
Norwalk 11
Augusta 10
Seattle 9
Torre del Greco 9
Dublin 8
Kunming 8
Ljubljana 8
Cagliari 7
Caserta 7
London 7
Scafati 7
Ann Arbor 6
Florence 6
Paris 6
Quarto 6
Trieste 6
Bologna 5
Brussels 5
Caivano 5
Council Bluffs 5
Fairfield 5
Los Angeles 5
Madrid 5
Mountain View 5
Rio Grande 5
Stockholm 5
Altamura 4
Canterbury 4
Centro 4
Changchun 4
Como 4
Cosenza 4
Falls Church 4
Gurgaon 4
Orange 4
Pune 4
San Francisco 4
Selargius 4
Seregno 4
Solofra 4
Turin 4
West Lafayette 4
Bari 3
Edinburgh 3
Fremont 3
Fuzhou 3
Hangzhou 3
Helsinki 3
Marigliano 3
New York 3
Nürnberg 3
Padova 3
Sagrado 3
San Mateo 3
Singapore 3
Trento 3
Vietri Sul Mare 3
Afragola 2
Avellino 2
Bonn 2
Brugherio 2
Cambridge 2
Camerino 2
Castelfidardo 2
Cercola 2
Chicago 2
Collecchio 2
Cork 2
Darmstadt 2
Totale 2.873
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Nome #
Nuovi ligandi per G-quadruplex: un approccio chimico-fisico nella terapia anti-cancro 106
1H NMR-based metabolomics study on follicular fluid from patients with Polycystic Ovary Syndrome 101
Characterisation of the dynamic interactions between complex N-glycans and human CD22 92
Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes 82
Bio-Inspired Dual-Selective BCL-2/c-MYC G-Quadruplex Binders: Design, Synthesis, and Anticancer Activity of Drug-like Imidazo[2,1-i]purine Derivatives 82
Aptameri formanti G-quadruplex per la terapia delle malattie da prioni 69
Common G-quadruplex binding agents found to interact with i-motif-forming DNA: Unexpected multi-target-directed compounds 66
A fast route for the synthesis of tetrazolyl oximes by a novel multicomponent reaction between Z-chlorooximes, isocyanides and trimethylsilyl azide 63
Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: a new opportunity in the targeting of G-rich DNA structures? 59
Conformational stability and DNA binding energetics of the rat thyroid transcription factor 1 homeodomain 57
Identification of novel interactors of human telomeric G-quadruplex DNA 56
Shooting for selective drug-like DNA G-quadruplex binders 55
Characterization of monovarietal extra virgin olive oils from the province of Béjaïa (Algeria) 55
NMR Assignment of N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide Seized as Herbal Incense for the First Time in Italy 54
Cyclodextrin-assisted assembly of PEGylated polyester nanoparticles decorated with folate 54
Targeting the BCL2 Gene Promoter G-Quadruplex with a New Class of Furopyridazinone-Based Molecules 54
Conformational stability and DNA binding energetics of the rat thyroid transcription factor 1 homeodomain 53
Fluorescence enhancement in G-quadruplex folding: synthesis, structure and stability of a novel dansyl-tagged, conjugated TBA 53
Binding of distamycin and analogues to quadruplex structures 52
Thermodynamic analysis of quadruplex DNA-drug interaction 51
Aspetti dell’interazione tra la distamicina-A e la quadruplex [d(TGGGGT)]4 51
Design, synthesis, biophysical and biological studies on trisubstituted naphthalimides as G-Quadruplex ligands 49
Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d(TGGGGT)]4 48
Identification of an acetal derivative of the piperonyl methyl ketone in tablets seized for suspected drug trafficking 47
Tetramolecular G-quadruplex Assembly: Effects of Polarity Site Inversions 45
Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-7 45
A new fluorescent TBA for early detection of thrombin: A biophysical study 44
Targeting the Human Telomeric G-Quadruplex Through Virtual Screening Calculations 44
Insights into telomeric G-quadruplex DNA recognition by HMGB1 protein 44
G-Quadruplex Binders Induce Immunogenic Cell Death Markers in Aggressive Breast Cancer Cells 44
Structural and conformational requisites in DNA quadruplex groove binding: Another piece to the puzzle 43
Analysis of quadruplex ligands by displacement isothermal titration calorimetry 43
Binding of TMPyP4 to higher-order telomeric quadruplexes: a biophysical study 43
Energetics of quadruplex-drug recognition in anticancer therapy 42
Thermodynamics and kinetics of PNA-DNA quadruplex-forming chimeras 42
Structural revision of clusianone and 7-epi-clusianone and anti-HIV activity of polyisoprenylated benzophenones 42
Binding and stability of G-quadruplexes: Insights from biocalorimetry 42
Tailoring a lead-like compound targeting multiple G-quadruplex structures 41
How are thermodynamically stable G-quadruplex-duplex hybrids? 40
Lead Discovery of Dual G-Quadruplex Stabilizers and Poly(ADP-ribose) Polymerases (PARPs) Inhibitors: A New Avenue in Anticancer Treatment 40
Binding of Harmine Derivatives to DNA: A Spectroscopic Investigation 40
Impact of phytosterols on liver and distal colon metabolome in experimental murine colitis model: an explorative study 40
Stability and binding properties of a modified Thrombin binding aptamer 39
Structural and conformational requisites in DNA quadruplex groove binding: Another piece to the puzzle 39
Fluorescence enhancement in G-quadruplex folding: Synthesis, structure and stability of a novel dansyl-tagged, conjugated TBA 39
A New DNA Structural Motif: The G-Triplex 39
A novel dansyl-labelled TBA15 analog showing fluorescence enhancement upon G-quadruplex formation for early detection of thrombin 39
Energetics of Biomolecular Interactions 38
Toward the Development of Specific G-Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives 38
HMGB1 binds to the KRAS promoter G-quadruplex: A new player in oncogene transcriptional regulation? 38
Monohydrazone Based G-Quadruplex Selective Ligands Induce DNA Damage and Genome Instability in Human Cancer Cells 38
Stabilità termodinamica del multimero del telomero umano ed energetica dell’interazione con la porfirina cationica 37
Interaction of azatrux with the G-quadruplex parallel fold: biophysical insight into the binding propietes to address drug design 37
Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations 37
Metodo per la preparazione di un supporto a basso legame aspecifico per cromatografia di affinità e/o sintesi diretta di oligonucleotidi 37
Targeting DNA quadruplexes with distamycin A and its derivatives: An ITC and NMR study 36
Thermodynamic analysis of Quadruplex DNA-drugs interaction 36
Analisi termodinamica dell’interazione tra ligandi e quadruple del DNA telomerico umano 36
Targeting of telomeric repeat-containing RNA G-quadruplexes: From screening to biophysical and biological characterization of a new hit compound 36
Effects of Sequence and Base Composition on the CD and TDS Profiles of i-DNA 36
Stability and binding properties of a modified thrombin binding aptamer 35
Biophysical study of the human telomeric quadruplexes-drugs interaction: a good starting point for anti cancer agents 35
Shooting for selective druglike G-quadruplex binders: evidence for telomeric DNA damage and tumor cell death 35
Looking for efficient G-quadruplex ligands: Evidence for selective stabilizing properties and telomere damage by drug-like molecules 35
Conformational plasticity of DNA secondary structures: probing the conversion between i-motif and hairpin species by circular dichroism and ultraviolet resonance Raman spectroscopies 35
Structural insight into the hTERT intron 6 sequence d(GGGGTGAAAGGGG) from 1H-NMR study 34
Selective Binding of Distamycin A Derivative to G-Quadruolex Structure [d(TGGGGT)]4 34
Bis-indole derivatives with antitumor activity turn out to be specific ligands of human telomeric G-quadruplex 34
Shooting for selective drug-like G-quadruplex binders: Evidence for telomeric DNA damage and tumor cell death 34
On the binding of naphthalene diimides to a human telomeric G-quadruplex multimer model 34
Interaction between prion protein and G-quadruplex-forming nucleic acids: a biophysical study 33
State-of-the-art methodologies for the discovery and characterization of DNA G-Quadruplex binders 32
Controlled Pore Glass-based oligonucleotide affinity support: towards High Throughput Screening methods for the identification of conformation-selective G-quadruplex ligands 32
Stability and binding properties of a modified Thrombin binding aptamer 31
Energetic Aspects of the recognition between G-Quadruplex structures and ligands 31
Application of "magnetic tongue" to the sensory evaluation of extra virgin olive oil 31
Biophysical properties of quadruplexes formed by PNA-DNA chimeras 30
BioCalorimetry of G-Quadruplex Structures 30
Applications of isothermal titration calorimetry in biophysical studies of G-quadruplexes 30
Assessing the influence of pH and cationic strength on i-motif DNA structure 30
Toward G-Quadruplex-Based Anticancer Agents: Biophysical and Biological Studies of Novel AS1411 Derivatives 30
Noncanonical DNA secondary structures as drug targets: The prospect of the i-motif 29
Shooting for Selective Drug-Like DNA G-Quadruplex Binders 29
Biophysical characterization of interaction between prion and G-quadruplex forming aptamers 29
Targeting multiple G-quadruplex–forming DNA sequences: Design, biophysical and biological evaluations of indolo-naphthyridine scaffold derivatives 29
A novel β-hairpin peptide derived from the ARC repressor selectively interacts with the major groove of B-DNA 29
Method for the preparation of a low unspecific binding-support for affinity chromatography and/or on-line synthesis of oligonucleotides 29
Cross-talk between prion protein and quadruplex-forming nucleic acids: a dynamic complex formation 28
New ligands for DNA telomeric G-quadruplexes: a thermodynamic approach towards anti-cancer therapy 28
Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics 27
Exploring the chemical space of G-quadruplex binders: Discovery of a novel chemotype targeting the human telomeric sequence 27
Targeting cKit87up quadruplex structure with short PNA sequences: a physico-chemical approach 27
Interfering with the Tumor-Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors 27
Structural and Conformational Requisites in DNA Quadruplex Groove Binding 25
Use of NMR in profiling of cocaine seizures 25
Interaction of azatrux to human telomeric DNA: A thermodynamic analysis 25
Interaction of azatrux with human telomeric G-quadruplex under molecular crowding conditions: biophysical and molecular modeling studies 25
Towards an analytical methodology for the screening of G-quadruplex-binding ligands 24
Structure of a Stable G-Hairpin 24
Differential scanning calorimetry to investigate G-quadruplexes structural stability 23
Totale 4.142
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Categoria #
all - tutte 18.843
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 18.843
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201916 0 0 0 0 0 0 0 0 0 0 7 9
2019/2020563 204 12 27 1 54 41 29 17 17 38 67 56
2020/2021467 27 21 33 25 52 97 47 34 50 24 45 12
2021/2022884 24 3 7 9 22 26 18 44 184 63 120 364
2022/20231.635 170 121 42 197 141 186 12 165 226 237 108 30
2023/2024723 41 144 179 61 38 54 24 143 24 15 0 0
Totale 5.122