IRIS
VIRGILIO, ANTONELLA
 Distribuzione geografica
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Continente #
AS - Asia 2.995
EU - Europa 2.819
NA - Nord America 2.600
SA - Sud America 453
AF - Africa 85
OC - Oceania 10
Totale 8.962
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Nazione #
US - Stati Uniti d'America 2.502
SG - Singapore 1.588
RU - Federazione Russa 1.155
IT - Italia 857
CN - Cina 656
BR - Brasile 371
VN - Vietnam 268
HK - Hong Kong 242
DE - Germania 148
FI - Finlandia 115
NL - Olanda 104
UA - Ucraina 86
IE - Irlanda 81
SE - Svezia 70
GB - Regno Unito 61
IN - India 57
CA - Canada 47
ZA - Sudafrica 35
JP - Giappone 33
MX - Messico 32
FR - Francia 31
AR - Argentina 28
PL - Polonia 27
CI - Costa d'Avorio 23
ID - Indonesia 20
TR - Turchia 20
PT - Portogallo 19
BD - Bangladesh 13
EC - Ecuador 12
ES - Italia 12
AU - Australia 10
AT - Austria 9
CL - Cile 9
CO - Colombia 9
KR - Corea 9
VE - Venezuela 9
IQ - Iraq 8
IR - Iran 8
PK - Pakistan 8
PY - Paraguay 8
AZ - Azerbaigian 7
AM - Armenia 6
BE - Belgio 6
IL - Israele 6
KZ - Kazakistan 6
UZ - Uzbekistan 6
CZ - Repubblica Ceca 5
AE - Emirati Arabi Uniti 4
CR - Costa Rica 4
MA - Marocco 4
PE - Perù 4
RO - Romania 4
TW - Taiwan 4
HU - Ungheria 3
KE - Kenya 3
KG - Kirghizistan 3
LT - Lituania 3
MY - Malesia 3
PH - Filippine 3
SA - Arabia Saudita 3
SD - Sudan 3
SK - Slovacchia (Repubblica Slovacca) 3
TN - Tunisia 3
YE - Yemen 3
BY - Bielorussia 2
DZ - Algeria 2
EE - Estonia 2
JM - Giamaica 2
KH - Cambogia 2
MD - Moldavia 2
MK - Macedonia 2
MU - Mauritius 2
NP - Nepal 2
PA - Panama 2
SI - Slovenia 2
SN - Senegal 2
TT - Trinidad e Tobago 2
UY - Uruguay 2
VC - Saint Vincent e Grenadine 2
AF - Afghanistan, Repubblica islamica di 1
AL - Albania 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BF - Burkina Faso 1
BG - Bulgaria 1
CD - Congo 1
CH - Svizzera 1
CV - Capo Verde 1
DO - Repubblica Dominicana 1
EG - Egitto 1
GA - Gabon 1
GE - Georgia 1
GP - Guadalupe 1
GR - Grecia 1
GT - Guatemala 1
GY - Guiana 1
HN - Honduras 1
HR - Croazia 1
JO - Giordania 1
Totale 8.950
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Città #
Singapore 738
Chandler 469
Moscow 276
Hong Kong 242
Beijing 218
Ashburn 212
Naples 203
Napoli 190
Santa Clara 124
Amsterdam 93
Millbury 80
Dong Ket 78
Jacksonville 78
Los Angeles 74
Princeton 71
Nanjing 69
Hefei 68
Boston 61
Ho Chi Minh City 57
Hanoi 38
Wilmington 36
Buffalo 35
Des Moines 33
Redondo Beach 32
São Paulo 32
Munich 30
Seattle 26
New York 25
Portici 24
Ann Arbor 23
Nanchang 21
Turku 20
Helsinki 19
Ottawa 19
Brooklyn 18
Houston 17
The Dalles 17
Hangzhou 16
Lawrence 15
Orem 15
Hebei 14
Rio de Janeiro 14
Rome 14
Shenyang 14
Boardman 13
Dearborn 13
Haiphong 13
Mexico City 13
Warsaw 13
Augusta 12
Chennai 12
Dallas 12
Falls Church 12
Formia 12
Jiaxing 12
Johannesburg 12
Caserta 11
Falkenstein 11
Marano Di Napoli 11
Milan 11
Paris 11
Phoenix 11
Poznan 11
Tianjin 11
Brasília 10
Changsha 10
Chicago 10
Denver 10
Kronberg 10
London 10
Toronto 10
Washington 10
Lappeenranta 9
Montreal 9
Nuremberg 9
San Francisco 9
Tokyo 9
Brisbane 8
Campinas 8
Guangzhou 8
Kochi 8
Lisbon 8
Mumbai 8
Nocera Inferiore 8
Poplar 8
Redwood City 8
Salvador 8
Seoul 8
Stockholm 8
Ankara 7
Belo Horizonte 7
Biên Hòa 7
Da Nang 7
Manchester 7
Norwalk 7
Pune 7
Salerno 7
Baku 6
Cape Town 6
Dublin 6
Totale 4.500
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Nome #
Pyrimido[5,4-d]Pyrimidine or pyrimidine derivates compounds and uses there of in the treatment of cancer 175
Ptaquiloside, the major carcinogen of bracken fern, in the pooled raw milk of healthy sheep and goats: an underestimated, global concern of food safety 143
A New Modified Thrombin Binding Aptamer Containing a 5'-5' Inversion of Polarity site 139
Structural and biological properties of novel G4-aptamer-drug conjugates as a vehicle for 5-fluoro-2′-deoxyuridine 135
Metastatic group 3 medulloblastoma is driven by PRUNE1 targeting NME1-TGF-β-OTX2-SNAIL via PTEN inhibition. 134
The ‘‘Janus face” of the thrombin binding aptamer: Investigating the anticoagulant and antiproliferative properties through straightforward chemical modifications 133
Antiproliferative Effects of the Aptamer d(GGGT) 4 and Its Analogues with an Abasic-Site Mimic Loop on Different Cancer Cells 132
5-Hydroxymethyl-2′-Deoxyuridine Residues in the Thrombin Binding Aptamer: Investigating Anticoagulant Activity by Making a Tiny Chemical Modification 130
MOLECULAR MODELLING STUDIES OF A PARALLEL STRANDED QUADRUPLEX CONTAING A 8-BROMOADENO 129
EFFECT OF THE INTRODUCTION OF AN A-RESIDUE INTO A QUADRUPLEX FORMING OLIGONUCLEOTIDE CONTAINING A 5'-5' POLARITY OF INVERSION SITE 129
A topological classification of G-quadruplex structures 122
MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines 121
A straightforward modification in the thrombin binding aptamer improving stability, affinity to thrombin and nuclease resistance 121
Backbone modified TBA analogues endowed with antiproliferative activity 121
Site specific replacements of a single loop nucleoside with a dibenzyl linker may switch the activity of TBA from anticoagulant to antiproliferative 119
Structural studies and biological evaluation of T30695 variants modified with single chiral glycerol-T reveal the importance of LEDGF/p75 for the aptamer anti-HIV-integrase activities 118
UL3 mediated nucleolar stress pathway as a new mechanism of action of antiproliferative G-quadruplex TBA derivatives in colon cancer cells 118
Quadruplex DNA: structural features and potential applications 116
8-Methyl-2'-deoxyguanosine incorporation into parallel DNA quadruplex structures 114
Effects of a 8-oxoadenosine Incorporation on Quadruplex structures: thermal stabilities and structural studies 114
Molecular Modelling Studies of Four Stranded Quadruplexes Containing a 3’-3’ or 5’-5’ Inversion of Polarity Site 113
G-triplex stability in human telomeric DNA with epigenetic modification/oxidative damage to thymine 112
Monomolecular G-quadruplex structures with inversion of polarity sites: new topologies and potentiality 111
Discovering New G-Quadruplex DNA Catalysts in Enantioselective Sulfoxidation Reaction 111
Expanding the potential of G-quadruplex structures: formation of a heterochiral TBA analogue 110
Unusual Chair-Like G-Quadruplex Structures: Heterochiral TBA Analogues Containing Inversion of Polarity Sites 107
A MINI-LIBRARY OF TBA ANALOGUES CONTAINING 3'-3' AND 5'-5' INVERSION OF POLARITY SITES 107
Aspetti dell’interazione tra la distamicina-A e la quadruplex [d(TGGGGT)]4 107
Novel pyrimidopyrimidine derivatives for inhibition of cellular proliferation and motility induced by h-prune in breast cancer 107
G-Quadruplex aptamer T30175 and its derivatives: exploring new potential anticancer activities 106
Exploring the binding of d(GGGT)4 to the HIV-1 integrase: An approach to investigate G-quadruplex aptamer/target protein interactions. 106
Structural properties and anticoagulant/cytotoxic activities of heterochiral enantiomeric thrombin binding aptamer (TBA) derivatives 106
PROBING THE EFFECTS OF CHEMICAL MODIFICATIONS ON THROMBIN BINDING APTAMER BIOLOGICAL ACTIVITY. 106
A NEW CLASS OF DNA QUADRUPLEX FORMED BY OLIGODEOXYRIBONUCLEOTIDES CONTAINING A 3’-3’ OR 5’-5’ INVERSION OF POLARITY SITE 105
Thrombin binding aptamer analogues containing inversion of polarity sites endowed with antiproliferative and anti-motility properties against Calu-6 cells 105
New G-quadruplex DNA catalysts in enantioselective sulfoxidation reaction 103
Exploring New Potential Anticancer Activities of the G-Quadruplexes Formed by [(GTG2T(G3T)3] and Its Derivatives with an Abasic Site Replacing Single Thymidine 103
Effects of 8-methylguanine on structure, stability and kinetics of formation of tetramolecular quadruplexes 102
Synthesis and structural study of quadruplex structures containing 2'-deoxy-8-methyladenosine 100
Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d(TGGGGT)]4 100
Site-specific replacement of the thymine methyl group by fluorine in thrombin binding aptamer significantly improves structural stability and anticoagulant activity 100
A new class of DNA quadruplexes formed by oligodeoxyribonucleotides containing a 3'-3' or 5'-5' inversion of polarity site 99
MiR-34a Targeting of Notch Ligand Delta-Like 1 ImpairsCD15+/CD133+ Tumor-Propagating Cells and SupportsNeural Differentiation in 99
Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops 98
PRELIMINARY STRUCTURAL INVESTIGATIONS ON THE ANTI-HIV G-QUADRUPLEX FORMING OLIGONUCLEOTIDE TGGGAG AND ANALOGUES: EVIDENCE FOR THE PRESENCE OF AN A-TETRAD 97
Heterochiral oligodeoxynucleotides forming quadruplex structures 95
A NEW CLASS OF DNA QUADRUPLEX FORMED BY OLIGODEOXYRIBONUCLEOTIDES CONTAINING A 3'-3' OR 5'-5' INVERSION OF POLARITY SITE 94
Transferrin-conjugated SNALPs encapsulating 2'-O-methylated miR-34a for the treatment of multiple myeloma. 94
EFFECT OF GUANINE BASES MODIFICATIONS AND L-DNA ON STABILITY AND KINETIC OF FORMATION OF TETRAMOLECULAR QUADRUPLEXES 93
Effects of abasic sites on structural, thermodynamic and kinetic properties of quadruplex structures. 92
The abasic site lesions in the human telomeric sequence d[TA(G3T2A)3G3]: A thermodynamic point of view 92
NUOVI INIBITORI PIRIMIDO-PIRIMIDINICI DELL'ATTIVITA' FOSFODIESTERASICA PRO-METASTASI DI H-PRUNE 92
Probing the Effects of Chemical Modifications on Anticoagulant and Antiproliferative Activity of Thrombin Binding Aptamer 90
Heterochiral oligodeoxynucleotides forming quadruplex structures 90
The insertion of two 8-methyl-2'-deoxyguanosineresidues in tetramolecular quadruplex structures:trying to orientate the strands 90
NMR STUDIES ON QUADRUPLEX STRUCTURES CONTAINING ABASIC SITES 90
THE ABASIC SITE LESIONS IN THE HUMAN TELOMERIC SEQUENCE d[TA(G3T2A)3G3]: A THERMODYNAMIC POINT OF VIEW 90
Structural and Biological Features of G-Quadruplex Aptamers as Promising Inhibitors of the STAT3 Signaling Pathway 89
PRELIMINARY STRUCTURAL INVESTIGATIONS ON THE ANTI-HIV G-QUADRUPLEX FORMING OLIGONUCLEOTIDE TGGGAG AND ANALOGUES: EVIDENCE FOR THE PRESENCE OF AN A-TETRAD 88
Aptamers against the β-conglutin allergen: Insights into the behavior of the shortest multimeric (intra)molecular dna gquadruplex 88
The oxidative damage to the human telomere: effects of 5-hydroxymethyl-2'-deoxyuridine on telomeric G-quadruplex structures 87
Effects of 8-Methyl-2'-deoxyadenosine incorporation into quadruplex forming oligonucleotides 87
Properties and Potential Antiproliferative Activity of Thrombin-Binding Aptamer (TBA) Derivatives with One or Two Additional G-Tetrads 87
Improved thrombin binding aptamer analogues containing inversion of polarity sites: structural effects of extra-residues at the ends 86
Improving the Biological Properties of Thrombin-Binding Aptamer by Incorporation of 8-Bromo-2′-Deoxyguanosine and 2′-Substituted RNA Analogues 85
EFFECTS OF THE SYN/ANTI EQUILIBRIUM MODULATION ON THE STRUCTURAL PROPERTIES OF TETRAMOLECULAR QUADRUPLEXES, 85
Unprecedented right- and left-handed quadruplex structures formed by heterochiral oligodeoxyribonucleotides 85
A further contribution to the extreme variability of quadruplex structures from oligodeoxyribonucleotides containing inversion of polarity sites in the G-tract 84
Investigating the properties of TBA variants with twin thrombin binding domains 84
STUDIES ON HETEROCHIRAL OLIGONUCLEOTIDES FORMING QUADRUPLEX STRUCTURES 83
A novel pyrimidine tetrad contributing to stabilize tetramolecular G-quadruplex structures. 83
Aptamer-Drug conjugates for a targeted and synergistic anticancer Response: Exploiting T30923-5-fluoro-2′-deoxyuridine (INT-FdU) derivatives 82
Design, synthesis, biophysical and biological studies on trisubstituted naphthalimides as G-Quadruplex ligands 82
NMR Structure of the Complex between Distamycin A and the Four Stranded Quadruplex Structure [d(TGGGGT)]4 81
GLI EFFETTI DELL’INTRODUZIONE DI SITI DI INVERSIONE DELLA POLARITA’ SULLA STRUTTURA QUADRUPLEX DEL DNA (TGGGT)4 81
Molecular modeling studies of a parallel stranded quadruplexes containing a 8-bromoadenosine 79
Structural Studies on LNA Quadruplexes 78
NMR STUDIES ON QUADRUPLEX STRUCTURES CONTAINING ABASIC SITES 78
Easy chemical modifications to explore the ‘Janus face’ of TBA: anticoagulant vs antiproliferative properties. 77
Easy chemical modifications to explore the ‘Janus face’ of TBA: anticoagulant vs antiproliferative properties. 77
Thrombin-Binding Aptamer (TBA) derivatives with one or two additional G-Tetrads: properties and potential antiproliferative activity 76
Formulazione costituita da snalp contenente pre-mir 34a utile per il trattamento del mieloma multiplo 76
Improved performances of catalytic G-quadruplexes (G4-DNAzymes) via the chemical modifications of the DNA backbone to provide Gquadruplexes with double 3′-external G-quartets 68
Trisubstituted naphthalimides for DNA quadruplex binding selectivity: synthesis, NMR and biophysical studies 67
The Introduction of Inversion of Polarity Sites in DNA G-Quadruplex Structures: Effects and Perspectives 67
Interaction of Distamycin A and its Derivatives with DNA QuadruplexStructures 66
GLI EFFETTI DELL'INTRODUZIONE DI SITI DI INVERSIONE DELLA POLARITA' SULLA STRUTTURA QUADRUPLEX DEL DNA (TGGGT)4 66
Human AP-endonuclease (Ape1) activity on telomeric G4 structures is modulated by acetylatable lysine residues in the N-terminal sequence 61
Studies on the influence of inversion of polarity sites on the dG residues glycosidic conformation in quadruplex structures 60
Effects of 5-Methyl-2′-Deoxycytidine in G-Quadruplex Forming Aptamers d(G3C)4 and d[GCG2(CG3)3C]: Investigating the Key Role of the Loops 59
Monomolecular G-quadruplex structures with inversion of polarity sites: new topologies and potentiality 56
Effects of the introduction of the inversion of polarity sites in the quadruplex forming oligonucleotide TGGGT. 55
miR-125b Upregulates miR-34a and Sequentially Activates Stress Adaption and Cell Death Mechanisms in Multiple Myeloma 49
Novel monomolecular derivatives of the anti-HIV-1 G-quadruplex-forming Hotoda's aptamer containing inversion of polarity sites 49
Strand directionality affects cation binding and movement within tetramolecular G-quadruplexes 46
Probing the importance of the G-quadruplex grooves for the activity of the anti-HIV-integrase aptamer T30923 45
A novel equilibrium relating to the helix handedness in G-quadruplexes formed by heterochiral oligonucleotides with an inversion of polarity site 44
More than one non-canonical phosphodiester bond in the G-tract: formation of unusual parallel G-quadruplex structures 44
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Totale 9.271
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Categoria #
all - tutte 29.008
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 29.008
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021333 0 0 0 0 0 58 30 24 90 6 41 84
2021/2022590 11 0 5 13 11 45 4 31 86 76 99 209
2022/20231.034 119 78 29 147 81 144 5 116 145 102 57 11
2023/2024486 18 85 39 30 30 47 19 95 9 7 75 32
2024/20252.579 122 130 8 13 132 127 313 173 160 251 952 198
2025/20263.051 485 423 568 453 979 143 0 0 0 0 0 0
Totale 9.271