IRIS
ZAMPELLA, ANGELA
 Distribuzione geografica
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Continente #
AS - Asia 10.493
NA - Nord America 8.621
EU - Europa 8.261
SA - Sud America 1.265
AF - Africa 275
OC - Oceania 10
Continente sconosciuto - Info sul continente non disponibili 9
Totale 28.934
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Nazione #
US - Stati Uniti d'America 8.246
SG - Singapore 4.672
RU - Federazione Russa 2.963
IT - Italia 2.434
CN - Cina 2.008
VN - Vietnam 1.692
BR - Brasile 1.005
HK - Hong Kong 839
DE - Germania 766
FI - Finlandia 518
FR - Francia 398
IE - Irlanda 288
BD - Bangladesh 272
JP - Giappone 222
NL - Olanda 213
CA - Canada 205
IN - India 199
GB - Regno Unito 190
UA - Ucraina 137
AR - Argentina 100
MX - Messico 94
KR - Corea 91
SE - Svezia 78
ZA - Sudafrica 72
ID - Indonesia 69
IQ - Iraq 60
PL - Polonia 56
PH - Filippine 55
CI - Costa d'Avorio 49
TH - Thailandia 46
ES - Italia 41
MA - Marocco 41
AT - Austria 39
TR - Turchia 38
EC - Ecuador 37
PK - Pakistan 36
TW - Taiwan 29
CL - Cile 25
UZ - Uzbekistan 25
CO - Colombia 24
VE - Venezuela 24
BE - Belgio 19
MY - Malesia 19
KE - Kenya 17
EG - Egitto 15
PE - Perù 14
PY - Paraguay 14
AZ - Azerbaigian 13
CH - Svizzera 13
LT - Lituania 13
AE - Emirati Arabi Uniti 12
ET - Etiopia 12
IL - Israele 12
JM - Giamaica 12
TN - Tunisia 12
NP - Nepal 11
UY - Uruguay 11
DZ - Algeria 10
PA - Panama 10
SA - Arabia Saudita 10
AL - Albania 9
CZ - Repubblica Ceca 9
BG - Bulgaria 8
CR - Costa Rica 8
HN - Honduras 8
IR - Iran 8
PT - Portogallo 8
RO - Romania 8
BO - Bolivia 7
GR - Grecia 7
NI - Nicaragua 7
OM - Oman 7
AU - Australia 6
LB - Libano 6
PS - Palestinian Territory 6
AO - Angola 5
GT - Guatemala 5
JO - Giordania 5
KG - Kirghizistan 5
LU - Lussemburgo 5
NG - Nigeria 5
RS - Serbia 5
BY - Bielorussia 4
DO - Repubblica Dominicana 4
GY - Guiana 4
KZ - Kazakistan 4
LV - Lettonia 4
SK - Slovacchia (Repubblica Slovacca) 4
SV - El Salvador 4
XK - ???statistics.table.value.countryCode.XK??? 4
BH - Bahrain 3
DJ - Gibuti 3
DK - Danimarca 3
GE - Georgia 3
GM - Gambi 3
HR - Croazia 3
KH - Cambogia 3
MT - Malta 3
MW - Malawi 3
TJ - Tagikistan 3
Totale 28.854
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Città #
Singapore 2.108
San Jose 1.310
Hong Kong 803
Naples 744
Moscow 679
Chandler 648
Ashburn 599
Beijing 525
Munich 496
Ho Chi Minh City 485
Santa Clara 394
Hanoi 371
Hefei 333
Millbury 268
Lauterbourg 261
Los Angeles 256
Princeton 224
Napoli 196
Helsinki 193
The Dalles 190
Tokyo 189
Boston 183
Nanjing 170
Buffalo 150
New York 136
Jacksonville 132
Dallas 129
Amsterdam 114
São Paulo 99
Redondo Beach 93
Wilmington 86
Des Moines 83
Rome 79
Ottawa 77
Council Bluffs 71
Milan 71
Turku 64
Da Nang 63
Nanchang 60
Seoul 60
Orem 53
Nuremberg 52
Frankfurt am Main 51
Houston 51
Warsaw 51
Brooklyn 50
Seattle 48
Haiphong 46
Mexico City 46
Shenyang 46
Dong Ket 44
Hebei 43
Torre del Greco 43
Chicago 41
Salerno 40
Perugia 39
Woodbridge 39
Atlanta 38
Lawrence 38
Montreal 38
Stockholm 37
Biên Hòa 36
Chennai 36
Pune 35
San Francisco 35
Phoenix 34
Tianjin 34
Jiaxing 33
London 33
Toronto 32
Denver 30
Johannesburg 29
Torre Annunziata 29
Casablanca 27
Jakarta 27
Norwalk 27
Angri 26
Falkenstein 26
Shanghai 26
Changsha 25
Manchester 25
Rio de Janeiro 25
Baghdad 24
Falls Church 24
Hải Dương 24
Tashkent 24
Ann Arbor 23
Belo Horizonte 23
Bologna 23
Formia 22
Porto Alegre 21
Brasília 20
Bangkok 19
Boardman 19
Poplar 19
Mumbai 18
Ankara 17
Dhaka 17
Lappeenranta 17
Bắc Giang 16
Totale 15.126
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Nome #
Discovery of UDCA derivatives as new modulators of bile acid receptors 300
Potent dual agonists of nuclear and membrane bile acid receptors 274
Guida Ragionata allo Svolgimento di Esercizi di Chimica Organica 264
Marine natural products as modulators of nuclear receptors 245
FXR mediates a chromatin looping in the GR promoter thus promoting the resolution of colitis in rodents 236
Natural and semisynthetic bile acids as Leukemia Inhibitory Factor (LIF) receptor antagonists 234
Design, Synthesis, and Pharmacological Evaluation of Dual FXR-LIFR Modulators for the Treatment of Liver Fibrosis 224
Characterisation of the dynamic interactions between complex N-glycans and human CD22 196
Liver GPBAR1 Associates With Immune Dysfunction in Primary Sclerosing Cholangitis and Its Activation Attenuates Cholestasis in Abcb4-/- Mice 179
Discovery of a Novel Class of Dual GPBAR1 Agonists-RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders 178
Design, synthesis and pharmacological characterization of novel potent nonsteroidal agonists of the farnesoid X receptor 178
Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain 171
Boswellia serrata: a rich source of triterpenes acting as antagonists of the leukemia inhibitory factor receptor 170
Novel Isoxazole Derivatives with Potent FXR Agonistic Activity Prevent Acetaminophen-Induced Liver Injury 170
Discovery of a Potent and Orally Active Dual GPBAR1/CysLT1R Modulator for the Treatment of Metabolic Fatty Liver Disease 170
Theonella swinhoei as a source of anti-inflammatory cyclopeptides 168
Activation of GPBAR1 attenuates vascular inflammation and atherosclerosis in a mouse model of NAFLD-related cardiovascular disease 165
Opposite effects of the FXR agonist obeticholic acid on Mafg and Nrf2 mediate the development of acute liver injury in rodent models of cholestasis 163
The leukemia inhibitory factor regulates fibroblast growth factor receptor 4 transcription in gastric cancer 157
Exploring Boswellia serrata Triterpenes: A New Frontier in Leukemia Inhibitory Factor Receptor Modulation 154
Solomonamides A and B: two unprecedented cyclic peptides from the marine sponge Theonella swinhoei 154
Inspection on bile acid scaffold in the discovery of the first example of LXRa/GPBAR1 dual agonists 153
Hyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonists 152
Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic Adenocarcinoma 150
Bile acids serve as endogenous antagonists of the Leukemia inhibitory factor (LIF) receptor in oncogenesis 150
Marine and semi-sinthetic hydroxystroids as new scaffolds for pregnane X receptor modulation 150
Expanding the Library of 1,2,4-Oxadiazole Derivatives: Discovery of New Farnesoid X Receptor (FXR) Antagonists/Pregnane X Receptor (PXR) Agonists 147
Plakilactones: a new class of marine agonists of the peroxisome proliferator-activated receptor ??? from Plakinastrella mamillaris 147
New G-quadruplex DNA catalysts in enantioselective sulfoxidation reaction 144
Synthesis of new isoxazole derivatives as fxr agonists with improved pharmacokinetic properties 144
Combinatorial therapy with BAR502 and UDCA resets FXR and GPBAR1 signaling and reverses liver histopathology in a model of NASH 143
Beneficial effects of UDCA and norUDCA in a rodent model of steatosis are linked to modulation of GPBAR1/FXR signaling 143
Structural Basis for Developing Multitarget Compounds Acting on Cysteinyl Leukotriene Receptor 1 and G-Protein-Coupled Bile Acid Receptor 1 143
Harnessing interrupted Fischer in continuous flow: sustainable synthesis of (spiro)indolenine and (spiro)indoline privileged scaffolds 142
Identification of new GPBAR1 selective agonists containing an epoxide group on cholane side chains 140
Discovery of Bile Acid Derivatives as Potent ACE2 Activators by Virtual Screening and Essential Dynamics 140
Perthamides C and D, two new potent anti-inflammatory cyclopeptides from a Solomon Lithistid sponge Theonella swinhoei 139
The first total synthesis of solomonsterol B, a marine pregnane X receptor agonist 139
Computer-Aided Drug Design Unveils the Structural Requisites for Bile Acid Receptors Modulation 139
Identification of cysteinyl-leukotriene-receptor 1 antagonists as ligands for the bile acid receptor GPBAR1 139
Bile acids derivatives in the selective modulation of FXR and GP-BAR1 138
Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma 137
Marine compounds as modulators of metabolic nuclear receptors: isolation, design, total synthesis and potential therapeutic application 137
Design and synthesis of hyodeoxycholic acid derivatives as GPBAR1 receptor modulators useful in the treatment of colon inflammation 137
Synthesis of a new class of isoxazole derivatives with a dual FXR agonistic and COX-2 inhibitory activity. 136
Discovery of ((1,2,4-oxadiazol-5-yl)pyrrolidin-3-yl)ureidyl derivatives as selective non-steroidal agonists of the G-protein coupled bile acid receptor-1 135
Conicasterol E, a small heterodimer partner sparing farnesoid-X-receptor modulator endowed with a pregnane-X-receptor agonistic activity, from the marine sponge Theonella swinhoei 134
Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists 134
Traduzione-CHIMICA ORGANICA Settima Edizione J. McMURRY 133
Towards new ligands of nuclear receptors. Discovery of malaitasterol A, an unique bis-secosterol from marine sponge Theonella swinhoei 133
BAR502/fibrate conjugates: synthesis, biological evaluation and metabolic profile 132
Development of bile acid activated receptors hybrid molecules for the treatment of inflammatory and metabolic disorders 131
Synthesis, Pharmacological Evaluation, and Molecular Modeling Studies of Novel Peptidic CAAX Analogues as Farnesyl-Protein-Transferase Inhibitors 130
Incisterols, highly degraded marine sterols, are a new chemotype of PXR agonists 129
Discovering New G-Quadruplex DNA Catalysts in Enantioselective Sulfoxidation Reaction 129
Discovery of new dual GPBAR1 /RORγt modulators with promising activity in the treatment of inflammation diseases 127
Combinatorial targeting of G-protein-coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug-induced liver injury 127
Synthesis of new bile acids derivatives as selective FXR/GPBAR1 ligands 127
Atorvastatin protects against liver and vascular damage in a model of diet induced steatohepatitis by resetting FXR and GPBAR1 signaling 125
Introduction of Nonacidic Side Chains on 6-Ethylcholane Scaffolds in the Identification of Potent Bile Acid Receptor Agonists with Improved Pharmacokinetic Properties 123
Discovery of cholanoic acid derivatives as new modulators of bile acid receptors 122
Discovery of deglucoruscin as a new aryl hydrocarbon receptor (AhR) agonist. 121
Modification on Ursodeoxycholic Acid (UDCA) Scaffold. Discovery of Bile Acid Derivatives As Selective Agonists of Cell-Surface G-Protein Coupled Bile Acid Receptor 1 (GP-BAR1) 121
Concise synthesis of AHMHA unit in perthamide C. Structural and stereochemical revision of perthamide C 121
Oxygenated Polyketides from Plakinastrella mamillaris as a New Chemotype of PXR Agonists 121
Inspection on bile acid scaffold in the discovery of the first example of LXR/GPBAR1 dual agonists 121
Speculation on 6-ethylcholane scaffold in the discovery of novel FXR and GPBAR1 ligands. 121
Synthesis and pharmacological evaluation of hybrid molecules containing fibrates and the semisynthetic bile acid derivative BAR502. 120
Thiazolidin-4-one-based compounds interfere with the eicosanoid biosynthesis pathways by mPGES-1/sEH/5-LO multi-target inhibition 120
Cystathionine γ-lyase, a H2S-generating enzyme, is a GPBAR1-regulated gene and contributes to vasodilation caused by secondary bile acids 120
Theonellasterols and Conicasterols from Theonella swinhoei. Novel marine natural ligands for human nuclear receptors 119
Synthesis of a new class of isoxazole derivatives with a dual FXR agonistic and COX-2 inhibitory activity 119
Plakinastrella mamillaris: a Rich Source of Bioactive Oxygenated Poliketides 118
4-Methylenesterols from Theonella swinhoei sponge are natural pregnane-X-receptor agonists and farnesoid-X-receptor antagonists that modulate innate immunity 117
Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists 117
Harnessing the Estradienone Scaffold to Develop Dual GPBAR1 and LIFR Modulators for Liver Fibrosis 116
Critical surveys covering the year 2005: total synthesis of natural products 116
Perthamide C Inhibits eNOS and iNOS Expression and Has Immunomodulating Activity In Vivo 116
Bile acids derivatives in the selective modulation of FXR and GPBAR1 116
Towards FXR selectivity: manipulation of 6-ethylcholane scaffold 116
The First Total Synthesis of Solomonsterol B, a Marine Pregnane X Receptor Agonist 115
Modification in the side chain of solomonsterol A: discovery of cholestan disulfate as a potent pregnane-X-receptor agonist 115
Preliminary structure-activity relationship on theonellasterol, a new chemotype of FXR antagonist, from the marine sponge Theonella swinhoei 115
The Role of Five-Membered Aromatic Rings Containing N and O in Modulating Bile Acid Receptors: An Overview 115
An advanced cellular assay for replicon-based antiviral screening of marine natural products 114
Epoxide functionalization on cholane side chains in the identification of G-protein coupled bile acid receptor (GPBAR1) selective agonists 113
Modification of semisynthetic bile acid derivatives as human receptor modulators 113
Investigation on bile acid receptor regulators. Discovery of cholanoic acid derivatives with dual G-protein coupled bile acid receptor 1 (GPBAR1) antagonistic and farnesoid X receptor (FXR) modulatory activity 112
Discovery of amine bile acid derivatives as selective agonists of cell-surface G-protein coupled bile acid receptor 1 112
Correction to “Discovery of a Novel Class of Dual GPBAR1 Agonists–RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders” 111
Preliminary SAR on theonellasterol, a new chemotype of FXR antagonist, from the marine sponge Theonella swinhoei 111
The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy 111
GPBAR1 activation by C6-substituted hyodeoxycholane analogues protect against colitis 110
Microbial-derived bile acid reverses inflammation in IBD via GPBAR1 agonism and RORγt inverse agonism 109
Isolation of new derivates of callipeltin C from the marine sponge Latrunculia sp. 109
Conicasterol E, a Small Heterodimer Partner Sparing Farnesoid X Receptor Modulator Endowed with a Pregnane X Receptor Agonistic Activity, from the Marine Sponge Theonella swinhoei 109
Chimica Organica 109
Leukemia inhibitory factor promotes human cholangiopathies, and its inhibition improves cholestasis in Abcb4 −/− mice 108
Sex and gender specific pitfalls and challenges in cardiac rehabilitation: a working hypothesis towards better inclusivity in cardiac rehabilitation programmes. 108
Perthamides C-F, potent human antipsoriatic cyclopeptides 108
Totale 14.133
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Categoria #
all - tutte 93.915
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 93.915
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.345 30 11 16 7 16 45 30 64 290 41 163 632
2022/20231.552 278 123 31 148 187 172 21 157 249 88 68 30
2023/20241.208 64 173 142 49 43 109 39 109 46 49 269 116
2024/20258.106 403 551 70 126 146 507 1.060 637 721 771 2.377 737
2025/202614.208 1.570 1.103 1.549 1.384 2.092 455 1.304 983 1.851 886 438 593
2026/2027370 370 0 0 0 0 0 0 0 0 0 0 0
Totale 29.399