Two new metabolites, perthamides C and D, have been isolated from the marine sponge Theonella swinhoei. Their structures were determined by interpretation of NMR and ESIMS data. All compounds exhibited in vivo potent anti-inflammatory activity. Biological activity and structural elucidation are reported.
Perthamides C and D, two new potent anti-inflammatory cyclopeptides from a Solomon Lithistid sponge Theonella swinhoei / Festa, Carmen; DE MARINO, Simona; Sepe, Valentina; Monti, M. C.; Luciano, P.; D'Auria, MARIA VALERIA; Debitus, C.; Bucci, Mariarosaria; Vellecco, V.; Zampella, Angela. - In: TETRAHEDRON. - ISSN 0040-4020. - 65:50(2009), pp. 10424-10429. [10.1016/j.tet.2009.10.026]
Perthamides C and D, two new potent anti-inflammatory cyclopeptides from a Solomon Lithistid sponge Theonella swinhoei
FESTA, CARMEN;DE MARINO, SIMONA;SEPE, VALENTINA;M. C. Monti;D'AURIA, MARIA VALERIA;BUCCI, MARIAROSARIA;V. Vellecco;ZAMPELLA, ANGELA
2009
Abstract
Two new metabolites, perthamides C and D, have been isolated from the marine sponge Theonella swinhoei. Their structures were determined by interpretation of NMR and ESIMS data. All compounds exhibited in vivo potent anti-inflammatory activity. Biological activity and structural elucidation are reported.| File | Dimensione | Formato | |
|---|---|---|---|
|
Perthamides C and D Tetrahedron 2009.pdf
non disponibili
Tipologia:
Documento in Post-print
Licenza:
Accesso privato/ristretto
Dimensione
253.59 kB
Formato
Adobe PDF
|
253.59 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
