PERISSUTTI, ELISA
 Distribuzione geografica
Continente #
NA - Nord America 2.043
EU - Europa 1.835
AS - Asia 578
AF - Africa 51
SA - Sud America 16
Continente sconosciuto - Info sul continente non disponibili 4
Totale 4.527
Nazione #
US - Stati Uniti d'America 2.000
IT - Italia 753
DE - Germania 268
CN - Cina 266
SG - Singapore 230
FR - Francia 159
NL - Olanda 149
IE - Irlanda 134
UA - Ucraina 130
FI - Finlandia 104
GB - Regno Unito 47
CI - Costa d'Avorio 46
CA - Canada 42
SE - Svezia 41
VN - Vietnam 28
IN - India 23
BR - Brasile 13
ES - Italia 12
TR - Turchia 12
BG - Bulgaria 10
IR - Iran 9
PL - Polonia 9
JP - Giappone 8
RU - Federazione Russa 5
EG - Egitto 4
EU - Europa 4
SK - Slovacchia (Repubblica Slovacca) 4
CL - Cile 3
BE - Belgio 2
CH - Svizzera 2
SI - Slovenia 2
CZ - Repubblica Ceca 1
EE - Estonia 1
HK - Hong Kong 1
JM - Giamaica 1
MA - Marocco 1
NO - Norvegia 1
PH - Filippine 1
RS - Serbia 1
Totale 4.527
Città #
Chandler 366
Naples 206
Singapore 168
Jacksonville 158
Amsterdam 144
Millbury 105
Princeton 98
Napoli 88
Nanjing 79
Menlo Park 76
Woodbridge 75
Beijing 68
Krefeld 50
Houston 48
Wilmington 44
Boston 43
Des Moines 42
Ottawa 41
Ashburn 34
Dong Ket 28
Santa Clara 27
Nanchang 25
Bad Bellingen 24
Ann Arbor 22
Hebei 19
Lawrence 19
San Giorgio a Cremano 18
Norwalk 16
Redwood City 16
Pozzuoli 14
Rome 14
Dearborn 13
Jiaxing 13
Augusta 11
Falls Church 11
Indiana 11
Mugnano di Napoli 11
Cambridge 10
Changsha 10
Salerno 10
Shenyang 10
Dublin 9
Milan 9
Sofia 9
Tianjin 9
Trieste 9
Ardabil 8
Pune 7
Roccarainola 7
Scunthorpe 7
Zola Predosa 7
Krakow 6
Kunming 6
San Mateo 6
Boardman 5
Council Bluffs 5
Ercolano 5
Falcone 5
Formia 5
Hangzhou 5
Kronberg 5
Rho 5
Afragola 4
Bacoli 4
Bratislava 4
Caserta 4
Casoria 4
Fucecchio 4
Los Angeles 4
New York 4
Orange 4
Santiago De Compostela 4
Yellow Springs 4
Aversa 3
Doshin 3
Fairfield 3
Fremont 3
Lappeenranta 3
Lucca 3
Marigliano 3
Ningbo 3
Padenghe sul Garda 3
Pomigliano d'Arco 3
Seattle 3
Serra 3
Tarragona 3
Valdagno 3
Vallo della Lucania 3
Verona 3
Avellino 2
Baltimore 2
Bari 2
Bologna 2
Campinas 2
Castel Volturno 2
Centro 2
Chofu 2
Garching 2
Guangzhou 2
Hanover 2
Totale 2.538
Nome #
1,2,4-Thiadiazolidin-3,5-diones as novel hydrogen sulfide donors 191
Design, Synthesis and Biological Evaluation of Novel N-Arylpiperazines Containing a 4,5-Dihydrothiazole Ring 177
MONTELUKAST ESTERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 99
Design of Sphingosine Kinases Inhibitors: Challenges and Recent Developments 78
Chemical Composition of PM10 at Urban Sites in Naples (Italy) 76
Development of 1,2,3-Triazole-Based Sphingosine Kinase Inhibitors and Their Evaluation as Antiproliferative Agents 73
Synthesis of phenylpyrimidinones as guanylyl cyclase C inhibitors 73
Antagonizing S1P3 receptor with cell-penetrating pepducins in skeletal muscle fibrosis 66
Heavy Metals Size Distribution in PM10 and Environmental-Sanitary Risk Analysis in Acerra (Italy) 62
The Role of 5-HT1A Receptor in the Cancer as a New Opportunity in Medicinal Chemistry 61
Synthesis of Arylpiperazine Derivatives as Protease Activated Receptor 1 Antagonists and Their Evaluation as Antiproliferative Agents 60
Combined Use of Factorial Design and Comparative Molecular Field Analysis (CoMFA): a Case Study. 58
BUDESONIDE 21-PHOSPHATE SALTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 58
Conformation-activity relationship of peptide T and new pseudocyclic hexapeptide analogs. 57
Synthesis, biological activity and conformational study of 1,4-benzoxazine dderivatives as potassium channel modulators. 56
Synthesis by microwave irradiation of a substituted benzoxazine parallel library with preferential relaxant activity for guinea pig trachealis 55
Pharmacokinetics of Dihydroergocristine and its major metabolite 8'-Hydroxy-Dihydroergocristine in Human plasma 55
Synthesis, in vitro and in vivo pharmacological evaluation of serotoninergic ligands containing an isonicotinic nucleus 54
New 5-HT1A, 5HT2Aand 5HT2Creceptor ligands containing a picolinic nucleus: Synthesis, in vitro and in vivo pharmacological evaluation 54
Synthesis and in Vitro Screening of New Series of 2,6-Dipeptidyl-anthraquinones: Influence of Side Chain Length on HIV-1 Nucleocapsid Inhibitors 53
Synthesis, Pharmacological Evaluation, and Molecular Modeling Studies of Novel Peptidic CAAX Analogues as Farnesyl-Protein-Transferase Inhibitors 52
Hybrids between H2S-donors and betamethasone 17-valerate or triamcinolone acetonide inhibit mast cell degranulation and promote hyperpolarization of bronchial smooth muscle cells 52
A suitable 1,2,4-oxadiazoles synthesis by microwave irradiation 50
A valuable synthesis of reduced peptide bond by microwave irradiation 49
Synthesis and Pharmacological Screening of Pyridopyrimidines as Effective Anti-Diarrheal Agents through the Suppression of Cyclic Nucleotide Accumulation 49
Synthesis, Chiral Resolution and Enantiomers Absolute Configuration of 4-Nitropropranolol and 7-Nitropropranolol 48
Synthesis of 6-beta-D-glucosyl and 6-nitroxy (-)-galanthamine derivatives as acetylcholinesterase inhibitors 47
Phenol derived CVFM analogs inhibitors of ras farnesyl transferase possessing cellular in vitro activity. 47
Non-Natural Linker Configuration in 2,6-Dipeptidyl-Anthraquinones Enhances the Inhibition of TAR RNA Binding/Annealing Activities by HIV-1 NC and Tat Proteins 47
Montelukast salts and pharmaceutical compositions containing the same 46
Synthesis and in vitro activities of NK-1 antagonists derived from L-Triptophan. 45
Synthesis, docking studies, and pharmacological evaluation of 5HT 2C ligands containing the N′-cyanoisonicotinamidine or N′-cyanopicolinamidine nucleus 45
Synthesis and Binding Affinities for 5-HT1A, 5-HT2A and 5-HT2C receptors of a series of 1- and 2-(4-arylpiperazinylalkyl)-4-(benzoyl)-1,2,3-triazole derivatives. 44
A convenient synthesis by microwave irradiation of an active metabolite (EXP-3174) of losartan. 44
Microwave Assisted Organic Synthesis of Heterocycles in Aqueous Media: Recent Advances in Medicinal Chemistry 44
Synthesis and antinociceptive Activity of Peptides Related to Interleukin-1b193-195 Lys-Pro-Thr. 43
Identification of a pepducin acting as S1P3 receptor antagonist 43
Level, potential sources of polycyclic aromatic hydrocarbons (PAHs) in particulate matter (PM10) in Naples 43
Microwave Solvent Free Regioselective 1,3 Dipolar Cycloaddition in the Synthesis of 1,4 Substituted [1,2,3]-Triazoles as Amide Bond Isosteres 42
A convenient strategy of dimerization by microwave heating and using 2,5-diketopiperazine as scaffold. 42
Development validation of LC-MS/MS method and determination of pharmacokinetic parameters of the stroke neuroprotectant neurounina-1 in beagle dog plasma after intravenous administration 42
Synthesis of Nα-Fmoc N,N′-bis-Boc-5-, 6- and 8-guanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid (5-GTIC, 6-GTIC and 8-GTIC) 41
The application of microwave irradiation as new convenient synthetic procedure in drug discovery 41
Identification of a novel selective CSE inhibitor through a combined pharmacological and metabolomic approach 41
Shape-dependent effects in a series of aromatic nitro compounds acting as mutagenic agents on S.typhimurium TA98. 39
null 39
Design, synthesis and biological evaluation of TAR and cTAR binders as HIV-​1 nucleocapsid inhibitors 39
New 5-Hydroxytryptamine1A Receptor Ligands Containing a Norbornene Nucleus: Synthesis and in Vitro Pharmacological Evaluation 38
Synthesis, Biological Evaluation and Docking Studies of PAR2-AP Derived Pseudopeptides as Inhibitors of Kallikrein 5 and 6 38
Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production 38
Comparative bioavailability of two losartan formulations in healthy human volunteers after a single dose administration. 37
Pharmacokinetic profile of atenolol aspirinate 37
Synthesis of 2-Methyl-3-indolylacetic Derivatives as Anti-Inflammatory Agents That Inhibit Preferentially Cyclooxygenase 1 without Gastric Damage 36
Efficient Microwave Combinatorial Parallel and Non Parallel Synthesis of N-Alkylated Glycine Methyl Esters as Peptide Building Blocks 35
Synthesis, Local Anesthetic Activity and QSAR Studies for a Set of N-[2-(alkylamino)-ethyl]benzotriazol-X-yl Acetamides. 35
Synthesis and In Vitro Pharmacological Evaluation of Novel 2-Hydroxypropyl-4-arylpiperazine Derivatives as Serotoninergic Ligands 35
5‑HT1A Receptor: An Old Target as a New Attractive Tool in Drug Discovery from Central Nervous System to Cancer 34
New Serotoninergic Ligands Containing Indolic and Methyl Indolic Nuclei: Synthesis and In Vitro Pharmacological Evaluation 34
Synthesis and Biological Activity of Benzotriazole Derivatives Structurally Related to Trazodone. 33
Efficient microwave combinatorial synthesis of novel indolic arylpiperazine derivatives as serotoninergic ligands 32
Design and synthesis of potential b-sheet nucleatorsvia Suzuki coupling reaction 32
Quantification of dapaconazole in human plasma using high-​performance liquid chromatography coupled to tandem mass spectrometry: Application to a phase I study 32
Structure-activity relationships study of isothiocyanates for H2S releasing properties: 3-Pyridyl-isothiocyanate as a new promising cardioprotective agent 32
Synthesis, docking studies, and pharmacological evaluation of 2-hydroxypropyl-4-arylpiperazine derivatives as serotoninergic ligands 32
Derivatives as 5HT1A receptor ligands-past and present. 31
New Potent 5-HT2A Receptor Ligands Containing a N'-Cyanopicolinamidine Nucleus: Synthesis and In Vitro Pharmacological Evaluation 31
Synthesis and Structure-Activity Relationships of Antiinflammatory 1-Methyl-2-(4-X-benzoyl)imidazole-5-acetic Acids. 31
Synthesis of benzamide derivatives and their evaluation as antiprion agents 31
PCB levels in adipose tissue of dogs from illegal dumping sites in Campania region (Italy) 31
Synthesis and structure-activity of antisense peptides corresponding to the region for CaM-binding domain of the inducible nitric oxide synthase 30
le microonde nella sintesi organica. fondamenti e applicazioni in chimica farmaceutica 30
New Insights into the Structure-Activity Relationship and Neuroprotective Profile of Benzodiazepinone Derivatives of Neurounina-1 as Modulators of the Na+/Ca2+Exchanger Isoforms 29
Probing the shape of a hydrophobic pocket in the active site of delta-opioid antagonists 28
Quantification of 3α-hydroxytibolone in human plasma by high performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS): Application in a bioequivalence study in healthy postmenopausal volunteers 28
H2S donating corticosteroids: Design, synthesis and biological evaluation in a murine model of asthma 28
Budesonide 21-phosphate sodium salt for use as anti-inflammatory or anti-asthmatic agent. 27
Human Tissue Kallikrein S1 Subsite Recognition of Non-Natural Basic Amino Acids 27
Synthesis of 1-naphthylpiperazine derivatives as serotoninergic ligands and their evaluation as antiproliferative agents. 27
Synthesis and Antiinflammatory-Analgesic Profile of 1-Methyl-2-(4-X-benzoyl)imidazole-5-carboxylic Acids. 27
Synthesis and hydrolysis by cathepsin B of fluorogenic substrates with the general structure benzoyl-X-ARG-MCA containing non-natural basic amino acids at position X 26
The role of in silico tools in supporting the application of the substitution principle 26
In vitro mutagenicity of anti-inflammatory parsalmide analogues PA7, PA10, and PA31 triggered by biotransformation into hydroxy derivatives 25
Synthesis and biological activity of pseudopeptides inhibitors of Ras farnesyl transferase containing unconventional amino acids. 25
The application of microwaves in combinatorial and high-throughput synthesis as new synthetic procedure in drug discovery. 25
Synthesis, Biological Activity and Conformational Study of 1,4-Benzoxazine Derivatives as Potassium Channel Modulators 25
Racemic synthesis and solid phase peptide synthesis application of the chimeric Valine/Leucine derivative 2-amino-3,3,4-trimethyl-pentanoic acid 25
HYBRIDS BETWEEN H2S-DONORS AND BETAMETHASONE 17-VALERATE OR TRIAMCINOLONE ACETONIDE: IN VITRO EFFECT IN ASTHMA TREATMENT 25
A convenient synthesis by microwave heating and pharmacological evaluation of novel benzoyltriazole and saccharine derivatives as 5-HT1A receptor ligands. 24
Synthesis of new 1,2,3-benzotriazin-4-one-arylpiperazine derivatives as 5-HT1A serotonin receptor ligands. 24
Synthesis of substituted benzamides as anti-inflammatory agents that inhibit preferentially cyclooxygenase 1 but do not cause gastric damage. 24
Synthesis and in vitro pharmacological evaluation of a new series of 5-HT1A 5-HT2A and 5-HT2C receptor ligands containing a norbornene nucleus. 24
Efficient microwave-assisted synthesis of 4-amino-2-benzazepin-3-ones as conformationally restricted dipeptide mimetics 23
Synthesis by microwave irradiation and binding properties of novel 5-HT1A receptor ligands. 23
Synthesis and Pharmacological Evaluation of a Set of N-[2-(Alkylamino)ethyl]benzotriazol-X-yl Isobutyramides Acting as Local Anesthetics. 23
Synthesis and neurokinin antagonist activity of 2-benzylidene- and 2- benzyl-3-benzylamino quinuclidines 23
Propylthiouracil quantification in human plasma by high-​performance liquid chromatography coupled with electrospray tandem mass spectrometry: Application in a bioequivalence study 23
H2s donors and their use in medicinal chemistry 23
Structure-Affinity Relationship Studies on Benzotriazole Derivatives Binding to 5-HT Receptor Subtypes. 22
Kallikrein Protease Activated Receptor (PAR) Axis: An Attractive Target for Drug Development 22
Synthesis and in Vitro Activities of Highly Potent Selective Tripeptide Antagonists of the Neurokinin NK-1 Receptor. 21
Totale 4.247
Categoria #
all - tutte 18.590
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 18.590


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020644 222 21 30 23 72 44 24 11 13 58 54 72
2020/2021433 15 33 31 28 45 44 47 6 43 11 83 47
2021/2022888 7 6 7 146 15 52 3 37 126 84 162 243
2022/2023927 139 112 19 89 73 83 15 62 120 141 52 22
2023/2024910 33 109 185 21 25 22 42 72 204 22 124 51
2024/2025175 175 0 0 0 0 0 0 0 0 0 0 0
Totale 4.760