IRIS
PERISSUTTI, ELISA
 Distribuzione geografica
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Continente #
EU - Europa 4.457
AS - Asia 3.996
NA - Nord America 3.646
SA - Sud America 609
AF - Africa 157
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 5
Totale 12.875
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Nazione #
US - Stati Uniti d'America 3.478
SG - Singapore 2.185
RU - Federazione Russa 1.808
IT - Italia 990
CN - Cina 951
BR - Brasile 490
DE - Germania 447
HK - Hong Kong 330
VN - Vietnam 207
FR - Francia 205
NL - Olanda 183
FI - Finlandia 180
UA - Ucraina 152
IE - Irlanda 138
GB - Regno Unito 115
CA - Canada 99
IN - India 70
SE - Svezia 54
CI - Costa d'Avorio 48
AR - Argentina 45
PL - Polonia 41
ES - Italia 40
ZA - Sudafrica 39
JP - Giappone 36
MX - Messico 36
BD - Bangladesh 32
GR - Grecia 27
MA - Marocco 26
TR - Turchia 25
EC - Ecuador 22
ID - Indonesia 21
PK - Pakistan 19
KR - Corea 18
AT - Austria 17
IQ - Iraq 15
IR - Iran 15
CO - Colombia 13
PY - Paraguay 12
BG - Bulgaria 11
LT - Lituania 11
CL - Cile 8
JO - Giordania 8
TN - Tunisia 8
UY - Uruguay 7
UZ - Uzbekistan 7
VE - Venezuela 7
LB - Libano 6
SA - Arabia Saudita 6
SN - Senegal 6
AE - Emirati Arabi Uniti 5
BE - Belgio 5
CZ - Repubblica Ceca 5
EG - Egitto 5
JM - Giamaica 5
AZ - Azerbaigian 4
EE - Estonia 4
EU - Europa 4
HN - Honduras 4
IL - Israele 4
NI - Nicaragua 4
SK - Slovacchia (Repubblica Slovacca) 4
TW - Taiwan 4
AM - Armenia 3
AO - Angola 3
AU - Australia 3
CH - Svizzera 3
DM - Dominica 3
DZ - Algeria 3
ET - Etiopia 3
KE - Kenya 3
KZ - Kazakistan 3
MY - Malesia 3
NP - Nepal 3
PH - Filippine 3
TT - Trinidad e Tobago 3
AL - Albania 2
BO - Bolivia 2
CM - Camerun 2
CR - Costa Rica 2
GE - Georgia 2
GT - Guatemala 2
HU - Ungheria 2
KG - Kirghizistan 2
LV - Lettonia 2
NO - Norvegia 2
PA - Panama 2
PE - Perù 2
PS - Palestinian Territory 2
SI - Slovenia 2
SV - El Salvador 2
SY - Repubblica araba siriana 2
YT - Mayotte 2
BA - Bosnia-Erzegovina 1
BS - Bahamas 1
BW - Botswana 1
BY - Bielorussia 1
BZ - Belize 1
CD - Congo 1
CU - Cuba 1
CV - Capo Verde 1
Totale 12.852
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Città #
Singapore 997
Moscow 433
Chandler 366
Beijing 333
Hong Kong 329
Naples 324
Ashburn 240
Santa Clara 214
San Jose 182
Jacksonville 158
Amsterdam 153
Hefei 109
Millbury 105
Princeton 97
Los Angeles 94
Napoli 88
Nanjing 81
Menlo Park 76
Woodbridge 75
Ho Chi Minh City 68
Munich 68
Houston 56
São Paulo 56
Buffalo 54
The Dalles 53
Boston 51
Redondo Beach 51
Krefeld 50
New York 50
Ottawa 46
Wilmington 44
Des Moines 43
Helsinki 39
Hanoi 38
Frankfurt am Main 34
Turku 32
Dallas 30
Falkenstein 29
Dong Ket 28
Brooklyn 26
Tokyo 26
Nanchang 25
Warsaw 25
Bad Bellingen 24
Ann Arbor 22
Mexico City 22
Milan 20
Toronto 20
Hebei 19
Lawrence 19
Rome 19
Casablanca 18
Chicago 18
Johannesburg 18
London 18
San Giorgio a Cremano 18
Seoul 18
Thessaloniki 18
Tianjin 18
Atlanta 17
Nuremberg 17
Norwalk 16
Pozzuoli 16
Redwood City 16
Chennai 15
Montreal 15
Orem 15
Seattle 14
Stockholm 14
Dearborn 13
Dublin 13
Jiaxing 13
Lahore 13
Changsha 12
Denver 12
Rio de Janeiro 12
Shenyang 12
Augusta 11
Bexley 11
Falls Church 11
Haiphong 11
Indiana 11
Mugnano di Napoli 11
Phoenix 11
Cambridge 10
Salerno 10
San Francisco 10
Vienna 10
Da Nang 9
Guangzhou 9
Lappeenranta 9
Manchester 9
Poplar 9
Porto Alegre 9
Pune 9
Sofia 9
Trieste 9
Amman 8
Ardabil 8
Athens 8
Totale 6.262
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Nome #
1,2,4-Thiadiazolidin-3,5-diones as novel hydrogen sulfide donors 326
Design, Synthesis and Biological Evaluation of Novel N-Arylpiperazines Containing a 4,5-Dihydrothiazole Ring 277
Development of 1,2,3-Triazole-Based Sphingosine Kinase Inhibitors and Their Evaluation as Antiproliferative Agents 165
Chemical Composition of PM10 at Urban Sites in Naples (Italy) 159
MONTELUKAST ESTERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 150
Design of Sphingosine Kinases Inhibitors: Challenges and Recent Developments 149
Synthesis of phenylpyrimidinones as guanylyl cyclase C inhibitors 146
Heavy Metals Size Distribution in PM10 and Environmental-Sanitary Risk Analysis in Acerra (Italy) 140
Antagonizing S1P3 receptor with cell-penetrating pepducins in skeletal muscle fibrosis 137
Synthesis of Arylpiperazine Derivatives as Protease Activated Receptor 1 Antagonists and Their Evaluation as Antiproliferative Agents 135
New 5-HT1A, 5HT2Aand 5HT2Creceptor ligands containing a picolinic nucleus: Synthesis, in vitro and in vivo pharmacological evaluation 133
Identification of a pepducin acting as S1P3 receptor antagonist 130
The Role of 5-HT1A Receptor in the Cancer as a New Opportunity in Medicinal Chemistry 130
Synthesis and in Vitro Screening of New Series of 2,6-Dipeptidyl-anthraquinones: Influence of Side Chain Length on HIV-1 Nucleocapsid Inhibitors 129
Synthesis and Pharmacological Screening of Pyridopyrimidines as Effective Anti-Diarrheal Agents through the Suppression of Cyclic Nucleotide Accumulation 129
Synthesis, Chiral Resolution and Enantiomers Absolute Configuration of 4-Nitropropranolol and 7-Nitropropranolol 128
Synthesis, in vitro and in vivo pharmacological evaluation of serotoninergic ligands containing an isonicotinic nucleus 126
A convenient synthesis by microwave irradiation of an active metabolite (EXP-3174) of losartan. 125
Non-Natural Linker Configuration in 2,6-Dipeptidyl-Anthraquinones Enhances the Inhibition of TAR RNA Binding/Annealing Activities by HIV-1 NC and Tat Proteins 125
HYBRIDS BETWEEN H2S-DONORS AND BETAMETHASONE 17-VALERATE OR TRIAMCINOLONE ACETONIDE: IN VITRO EFFECT IN ASTHMA TREATMENT 124
Development validation of LC-MS/MS method and determination of pharmacokinetic parameters of the stroke neuroprotectant neurounina-1 in beagle dog plasma after intravenous administration 123
Synthesis, biological activity and conformational study of 1,4-benzoxazine dderivatives as potassium channel modulators. 122
Level, potential sources of polycyclic aromatic hydrocarbons (PAHs) in particulate matter (PM10) in Naples 122
Synthesis, docking studies, and pharmacological evaluation of 5HT 2C ligands containing the N′-cyanoisonicotinamidine or N′-cyanopicolinamidine nucleus 121
A New Process for the Synthesis of Budesonide 21-Phosphate and Evaluation in a Murine Model of Inflammation 120
Hybrids between H2S-donors and betamethasone 17-valerate or triamcinolone acetonide inhibit mast cell degranulation and promote hyperpolarization of bronchial smooth muscle cells 119
Synthesis, Biological Evaluation and Docking Studies of PAR2-AP Derived Pseudopeptides as Inhibitors of Kallikrein 5 and 6 117
Synthesis and Binding Affinities for 5-HT1A, 5-HT2A and 5-HT2C receptors of a series of 1- and 2-(4-arylpiperazinylalkyl)-4-(benzoyl)-1,2,3-triazole derivatives. 116
Phenol derived CVFM analogs inhibitors of ras farnesyl transferase possessing cellular in vitro activity. 116
Synthesis and In Vitro Pharmacological Evaluation of Novel 2-Hydroxypropyl-4-arylpiperazine Derivatives as Serotoninergic Ligands 116
Microwave Assisted Organic Synthesis of Heterocycles in Aqueous Media: Recent Advances in Medicinal Chemistry 116
3-Nitroatenolol: First Synthesis, Chiral Resolution and Enantiomers’ Absolute Configuration 115
Pharmacokinetics of Dihydroergocristine and its major metabolite 8'-Hydroxy-Dihydroergocristine in Human plasma 114
Synthesis and in vitro activities of NK-1 antagonists derived from L-Triptophan. 114
Synthesis, Pharmacological Evaluation, and Molecular Modeling Studies of Novel Peptidic CAAX Analogues as Farnesyl-Protein-Transferase Inhibitors 113
New Potent 5-HT2A Receptor Ligands Containing a N'-Cyanopicolinamidine Nucleus: Synthesis and In Vitro Pharmacological Evaluation 113
Isothiocyanate-Corticosteroid Conjugates against asthma: Unity makes strength 112
Prednisone-hydrogen sulfide releasing hybrid shows improved therapeutic profile in asthma 112
Budesonide 21-phosphate sodium salt for use as anti-inflammatory or anti-asthmatic agent. 111
Combined Use of Factorial Design and Comparative Molecular Field Analysis (CoMFA): a Case Study. 111
5‑HT1A Receptor: An Old Target as a New Attractive Tool in Drug Discovery from Central Nervous System to Cancer 111
Synthesis and antinociceptive Activity of Peptides Related to Interleukin-1b193-195 Lys-Pro-Thr. 110
A convenient strategy of dimerization by microwave heating and using 2,5-diketopiperazine as scaffold. 110
Synthesis by microwave irradiation of a substituted benzoxazine parallel library with preferential relaxant activity for guinea pig trachealis 109
Conformation-activity relationship of peptide T and new pseudocyclic hexapeptide analogs. 109
Synthesis, Docking Studies and Pharmacological Evaluation of Serotoninergic Ligands Containing a 5-Norbornene-2-Carboxamide Nucleus 108
New Serotoninergic Ligands Containing Indolic and Methyl Indolic Nuclei: Synthesis and In Vitro Pharmacological Evaluation 108
Design, synthesis and biological evaluation of TAR and cTAR binders as HIV-​1 nucleocapsid inhibitors 107
PCB levels in adipose tissue of dogs from illegal dumping sites in Campania region (Italy) 107
Synthesis, Local Anesthetic Activity and QSAR Studies for a Set of N-[2-(alkylamino)-ethyl]benzotriazol-X-yl Acetamides. 106
Newly Synthesized Indolylacetic Derivatives Reduce Tumor Necrosis Factor-Mediated Neuroinflammation and Prolong Survival in Amyotrophic Lateral Sclerosis Mice 106
H2s donors and their use in medicinal chemistry 105
Synthesis of benzamide derivatives and their evaluation as antiprion agents 104
Racemic synthesis and solid phase peptide synthesis application of the chimeric Valine/Leucine derivative 2-amino-3,3,4-trimethyl-pentanoic acid 103
A valuable synthesis of reduced peptide bond by microwave irradiation 102
Structure-activity relationships study of isothiocyanates for H2S releasing properties: 3-Pyridyl-isothiocyanate as a new promising cardioprotective agent 101
Synthesis and Biological Activity of Benzotriazole Derivatives Structurally Related to Trazodone. 100
Synthesis, Biological Activity and Conformational Study of 1,4-Benzoxazine Derivatives as Potassium Channel Modulators 100
BUDESONIDE 21-PHOSPHATE SALTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 100
Design, Synthesis and Evaluation of Novel Molecular Hybrids between Antiglaucoma Drugs and H2S Donors 97
Synthesis of Nα-Fmoc N,N′-bis-Boc-5-, 6- and 8-guanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid (5-GTIC, 6-GTIC and 8-GTIC) 97
Synthesis and vasorelaxant activity of new 1,4-benzoxazine derivatives potassium channel openers. 97
Synthesis of 1-naphthylpiperazine derivatives as serotoninergic ligands and their evaluation as antiproliferative agents. 97
Quantification of dapaconazole in human plasma using high-​performance liquid chromatography coupled to tandem mass spectrometry: Application to a phase I study 97
Synthesis of substituted benzamides as anti-inflammatory agents that inhibit preferentially cyclooxygenase 1 but do not cause gastric damage. 96
le microonde nella sintesi organica. fondamenti e applicazioni in chimica farmaceutica 96
Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production 96
Identification of a novel selective CSE inhibitor through a combined pharmacological and metabolomic approach 95
Synthesis and Structure-Activity Relationships of Antiinflammatory 1-Methyl-2-(4-X-benzoyl)imidazole-5-acetic Acids. 94
Synthesis, docking studies, and pharmacological evaluation of 2-hydroxypropyl-4-arylpiperazine derivatives as serotoninergic ligands 94
Trends in h2s-donors chemistry and their effects in cardiovascular diseases 94
Arylpiperazine Derivatives and Cancer: A New Challenge in Medicinal Chemistry 92
Microwave Solvent Free Regioselective 1,3 Dipolar Cycloaddition in the Synthesis of 1,4 Substituted [1,2,3]-Triazoles as Amide Bond Isosteres 92
The application of microwave irradiation as new convenient synthetic procedure in drug discovery 92
Synthesis by microwave irradiation and binding properties of novel 5-HT1A receptor ligands. 90
Synthesis of new 1,2,3-benzotriazin-4-one-arylpiperazine derivatives as 5-HT1A serotonin receptor ligands. 90
A suitable 1,2,4-oxadiazoles synthesis by microwave irradiation 88
A convenient synthesis by microwave heating and pharmacological evaluation of novel benzoyltriazole and saccharine derivatives as 5-HT1A receptor ligands. 88
Propylthiouracil quantification in human plasma by high-​performance liquid chromatography coupled with electrospray tandem mass spectrometry: Application in a bioequivalence study 88
New 5-Hydroxytryptamine1A Receptor Ligands Containing a Norbornene Nucleus: Synthesis and in Vitro Pharmacological Evaluation 87
Synthesis and Antiinflammatory-Analgesic Profile of 1-Methyl-2-(4-X-benzoyl)imidazole-5-carboxylic Acids. 87
H2S donating corticosteroids: Design, synthesis and biological evaluation in a murine model of asthma 87
Synthesis and structure-activity of antisense peptides corresponding to the region for CaM-binding domain of the inducible nitric oxide synthase 85
Comparative bioavailability of two losartan formulations in healthy human volunteers after a single dose administration. 85
Kallikrein Protease Activated Receptor (PAR) Axis: An Attractive Target for Drug Development 85
New Insights into the Structure-Activity Relationship and Neuroprotective Profile of Benzodiazepinone Derivatives of Neurounina-1 as Modulators of the Na+/Ca2+Exchanger Isoforms 85
Synthesis and biological activity of tripeptide FR113680 analogues containing unconventional amino acids. 83
Synthesis and biological activity of pseudopeptides inhibitors of Ras farnesyl transferase containing unconventional amino acids. 82
Probing the shape of a hydrophobic pocket in the active site of delta-opioid antagonists 81
Synthesis of 2-Methyl-3-indolylacetic Derivatives as Anti-Inflammatory Agents That Inhibit Preferentially Cyclooxygenase 1 without Gastric Damage 81
Preparation and local anesthetic activity of benzotriazinone and benzoyltriazole derivatives. 81
Synthesis of 6-beta-D-glucosyl and 6-nitroxy (-)-galanthamine derivatives as acetylcholinesterase inhibitors 79
Efficient Microwave Combinatorial Parallel and Non Parallel Synthesis of N-Alkylated Glycine Methyl Esters as Peptide Building Blocks 78
Montelukast salts and pharmaceutical compositions containing the same 78
Microwave-enhanced solution coupling of the a,a-dialkyl amino acid, Aib 76
Structure-Affinity Relationship Studies on Benzotriazole Derivatives Binding to 5-HT Receptor Subtypes. 76
In vitro mutagenicity of anti-inflammatory parsalmide analogues PA7, PA10, and PA31 triggered by biotransformation into hydroxy derivatives 75
Microwave enhanced solution synthesis of 1,4-benzodiazepin-5-ones. 75
Minimal structural requirements for agonist activity of PAR-2 activating peptides. 75
Shape-dependent effects in a series of aromatic nitro compounds acting as mutagenic agents on S.typhimurium TA98. 74
Totale 10.957
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Categoria #
all - tutte 44.219
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 44.219
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021237 0 0 0 0 0 0 47 6 43 11 83 47
2021/2022888 7 6 7 146 15 52 3 37 126 84 162 243
2022/2023924 138 112 19 89 73 83 15 62 120 139 52 22
2023/2024902 33 107 183 21 25 20 41 72 204 22 123 51
2024/20254.064 194 216 56 82 74 255 393 288 262 460 1.461 323
2025/20264.493 806 462 833 620 1.241 270 261 0 0 0 0 0
Totale 13.131