IRIS
MELILLO, ROSA MARINA
 Distribuzione geografica
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Continente #
NA - Nord America 2.006
EU - Europa 1.663
AS - Asia 341
AF - Africa 38
OC - Oceania 2
Continente sconosciuto - Info sul continente non disponibili 1
SA - Sud America 1
Totale 4.052
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Nazione #
US - Stati Uniti d'America 1.954
IT - Italia 767
CN - Cina 287
UA - Ucraina 242
DE - Germania 157
FI - Finlandia 132
IE - Irlanda 131
SE - Svezia 94
NL - Olanda 76
CA - Canada 50
CI - Costa d'Avorio 37
GB - Regno Unito 34
IN - India 25
VN - Vietnam 12
FR - Francia 7
SG - Singapore 6
PH - Filippine 5
AT - Austria 3
BE - Belgio 3
BG - Bulgaria 3
AU - Australia 2
JP - Giappone 2
MX - Messico 2
PL - Polonia 2
RO - Romania 2
SK - Slovacchia (Repubblica Slovacca) 2
AE - Emirati Arabi Uniti 1
AL - Albania 1
BD - Bangladesh 1
BR - Brasile 1
CH - Svizzera 1
CZ - Repubblica Ceca 1
EG - Egitto 1
ES - Italia 1
EU - Europa 1
GR - Grecia 1
IR - Iran 1
LU - Lussemburgo 1
NO - Norvegia 1
RU - Federazione Russa 1
TR - Turchia 1
Totale 4.052
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Città #
Chandler 385
Jacksonville 268
Princeton 132
Millbury 122
Nanjing 100
Napoli 95
Ashburn 92
Boston 79
Amsterdam 76
Naples 71
Wilmington 55
Ann Arbor 54
Beijing 54
Ottawa 47
Nanchang 32
Rome 25
Hebei 23
Kronberg 22
Des Moines 20
Boardman 16
Norwalk 16
Falls Church 15
Salerno 15
Krefeld 14
Shenyang 14
Woodbridge 14
Tianjin 13
Cagliari 12
Dong Ket 12
Milan 12
Bacoli 11
Barano d'Ischia 11
Changsha 10
Augusta 8
Bari 8
Jiaxing 8
Kunming 8
Shanghai 8
Verona 8
Orange 7
Perugia 7
Portici 7
Pune 7
Racale 7
Freiburg im Breisgau 6
Lawrence 6
Catania 5
Florence 5
Hangzhou 5
Indiana 5
Misterbianco 5
Redmond 5
Brescia 4
Formia 4
General Trias 4
Leawood 4
Mumbai 4
Paterno 4
Pisa 4
San Mateo 4
Seattle 4
Trieste 4
Turin 4
Caserta 3
Clamart 3
Dearborn 3
Dublin 3
Fondi 3
Genoa 3
London 3
Los Angeles 3
Palermo 3
Simi Valley 3
Sofia 3
Vedelago 3
Washington 3
Zhengzhou 3
Bentley 2
Brindisi 2
Buffalo 2
Carignano 2
Casoria 2
Council Bluffs 2
Courcelles 2
Dallas 2
Enterprise 2
Figline Valdarno 2
Fisciano 2
Forino 2
Jinan 2
Lappeenranta 2
Montecorvino Rovella 2
Montesarchio 2
New York 2
Osaka 2
Potenza 2
Pozzallo 2
Redwood City 2
San Francisco 2
San Giorgio del Sannio 2
Totale 2.194
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Nome #
Basi molecolari dell’effetto pro-tumorigenico dele chemochine nel cancro della tiroide. 367
New perspectives in cancer: Modulation of lipid metabolism and inflammation resolution 75
The Impact of Resolution of Inflammation on Tumor Microenvironment: Exploring New Ways to Control Cancer Progression 74
PD-1 blockade delays tumor growth by inhibiting an intrinsic SHP2/Ras/MAPK signalling in thyroid cancer cells. 70
HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity 67
Il Sistema Immunitario 66
Mast cells induce epithelial-to-mesenchymal transition and stem cell features in human thyroid cancer cells through an IL-8-Akt-Slug pathway. 64
Formyl Peptide Receptor 1 Suppresses Gastric Cancer Angiogenesis and Growth by Exploiting Inflammation Resolution Pathways 63
AXL is an oncotarget in human colorectal cancer 57
Biochemical and molecular characterization of the novel BRAF(V599Ins) mutation detected in a classic papillary thyroid carcinoma. 56
Autocrine stimulation by osteopontin plays a pivotal role in the expression of the mitogenic and invasive phenotype of RET/PTC-transformed thyroid cells. 55
RET/papillary thyroid carcinoma oncogenic signaling through the Rap1 small GTPase 54
Peptide per rigenerare i tessuti lesionati. 54
Thyroid targeting of the N-ras(Gln61Lys) oncogene in transgenic mice results in follicular tumors that progress to poorly differentiated carcinomas. 51
Signal Transducer and Activator of Transcription 1 Plays a Pivotal Role in RET/PTC3 Oncogene-induced Expression of Indoleamine 2,3-Dioxygenase 1 51
Mast cells have a protumorigenic role in human thyroid cancer. 50
Activation of the Erk8 mitogen-activated protein (MAP) kinase by RET/PTC3, a constitutively active form of the RET proto-oncogene. 48
Formyl peptide receptors at the interface of inflammation, angiogenesis and tumor growth 48
IL-8, But Not The Related Chemokine CXCL1, Sustains An Autocrine Circuit Necessary For the Properties and Functions of Thyroid Cancer Stem Cells. 48
BRAF is a therapeutic target in aggressive thyroid carcinoma. 46
A cell proliferation and chromosomal instability signature in anaplastic thyroid carcinoma. 43
Therapeutic strategies to target the receptor tyrosine kinase AXL in thyroid cancer 42
Activation of RET oncogene and thyroid carcinogenesis 41
Multiple anti-tumor effects of Reparixin on thyroid cancer 41
Role of Formyl Peptide Receptors In Gastrointestinal Healing 40
null 39
Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer. 39
Regulation of p27Kip1 protein levels contributes to mitogenic effects of the RET/PTC kinase in thyroid carcinoma cells. 39
In PD-1+ human colon cancer cells NIVOLUMAB promotes survival and could protect tumor cells from conventional therapies 39
Activation of TYRO3/AXL tyrosine kinase receptors in thyroid cancer. 38
Genetics: The genomic landscape of papillary thyroid carcinoma 38
Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer. 37
The oncogenic activity of RET point mutants for follicular thyroid cells may account for the occurrence of papillary thyroid carcinoma in patients affaected by familial medullary thyroid carcinoma. 37
The PTC oncogene is able to dedifferentiate a rat thyroid epithelial cell line in culture 36
Helicobacter pylori Hp(2-20) promotes gastric mucosal healing and interacts with formyl-peptide receptors 36
The formyl peptide receptor 1 exerts a tumor suppressor function in human gastric cancer by inhibiting angiogenesis. 36
Functional expression of the CXCR4 chemokine receptor is induced by RET/PTC oncogenes and is a common event in human papillary thyroid carcinomas 35
Thyroid cancer and inflammation. 35
RET/PTC activation in papillary thyroid carcinoma: European Journal of Endocrinology Prize Lecture. 33
Overexpression of the Cytokine Osteopontin Identifies Aggressive Laryngeal Squamous Cell Carcinomas and Enhances Carcinoma Cell Proliferation and Invasiveness. 33
Positive and negative regulation of cell proliferation by E2F-1: influence of protein level and human papillomavirus oncoproteins 32
Receptor- and non-receptor tyrosine kinases induce processing of the amyloid precursor protein: role of the low-density lipoprotein receptor-related protein. 32
Recent advances in understanding immune phenotypes of thyroid carcinomas: Prognostication and emerging therapies [version 1; referees: 2 approved] 32
Osteopontin is overexpressed in human papillary thyroid carcinomas and enhances thyroid carcinoma cell invasiveness 31
Functional role of the CXCR4 chemokine receptor in thyroid cancer. 31
A new germline RET mutation apparently devoid of transforming activity serendipitously discovered in a patient with atrophic autoimmune thyroiditis and primary ovarian failure. 31
AXL Is a Novel Predictive Factor and Therapeutic Target for Radioactive Iodine Refractory Thyroid Cancer 31
Genetic Alterations in differentiated thyroid cancer:what can be expected for gene expression profiling of thyroid carcinomas 30
Different mutations of the RET gene cause different human tumoral diseases. 30
The disruption of the CCDC6 - PP4 axis induces a BRCAness like phenotype and sensitivity to PARP inhibitors in high-grade serous ovarian carcinoma 29
The Insulin Receptor Substrate (IRS)-1 recruits Phosphatidylinositol 3-Kinase to Ret: evidence for a competition between Shc and IRS-1 for the binding to Ret. 29
Cytokines, Chemokines and thyroid remodeling 29
Biological role and potential therapeutic targeting of the chemokine receptor CXCR4 in undifferentiated thyroid cancer 29
Cloning and characterization of H4 (D10S170), a gene involved in RET rearrangements in vivo. 28
L’osteopontina: un nuovo marcatore biologico dei carcinomi della testa e del collo 28
Inflammation in thyroid oncogenesis. 28
The Formyl Peptide Receptor 1 Exerts a Tumor Suppressor Role in Human Gastric Cancer by Suppressing Angiogenesis 28
OPN/CD44v6 overexpression in laryngeal dysplasia and correlation with clinical outcome. 27
Molecular Mechanism of RET in Human Cancer 27
CXCR4 expression correlates with the degree of tumor infiltration and BRAF status in papillary thyroid carcinomas. 27
Editorial: Novel Mechanism of Radioactive Iodine Refractivity in Thyroid Cancer 26
Toll‐like receptor 7 mediates inflammation resolution and inhibition of angiogenesis in non‐small cell lung cancer 26
Small-molecule inhibitors of chemokine receptors as novel anticancer therapy of human thyroid carcinomas. 25
A new germline point mutation in Ret exon 8 (cys515ser) in a family with medullary thyroid carcinoma. 25
Helicobacter pylori Hp(2-20) promotes migration and proliferation of gastric epithelial cells by interacting with formyl peptide receptors in vitro and accelerates gastric mucosal healing in vivo. 25
RET ONCOGENE ACTIVATION IN HUMAN THYROID NEOPLASMS IS RESTRICTED TO THE PAPILLARY CANCER SUBTYPE 24
Molecular basis of thyroid cancer: role of inflammatory cells and molecules 24
Potent mitogenicity of the RET/PTC3 oncogene correlates with its prevalence in tall-cell variant of papillary thyroid carcinoma 23
Signalling of the Ret receptor tyrosine kinase through the c-Jun NH2-terminal Protein Kinases (JNKs): evidence for a divergence of the ERKs and JNKs pathways induced by Ret. 23
INCREASED IN-VIVO PHOSPHORILATION OF RET TYROSINE 1062 IS A POTENTIAL PATHOGENETIC MECHANISM OF MULTIPLE ENDOCRINE NEOPLASIA TYPE 2B. 23
Tyrosines 1015 and 1062 are in vivo auto-phosphorylation site in Ret and Ret-derived oncoproteins 23
Differential diagnosis of thyroid nodules using fine-needle aspiration cytology and oncogene mutation screening: are we ready? 23
Molecular heterogeneity of RET loss of function in Hirschsprung's disease. 22
Tyrosine 1062 of RET-MEN2A mediates activation of Akt(PKB) and MAPK pathways leading to PC12 cell survival. 22
Molecular mechanisms of RET activation in human cancer 22
Molecular biology of the MEN2 gene 22
Serum soluble ST2 and interleukin-33 levels in patients with pulmonary arterial hypertension. 22
Molecular mechanism of 17-allylamino-17-demethoxygeldanamycin (17-AAG)-induced AXL receptor tyrosine kinase degradation. 22
Probiotic Lactobacillus rhamnosus GG (LGG) restrains the angiogenic potential of colorectal carcinoma cells by activating a proresolving program via formyl peptide receptor 1 21
Tyrosine 1062 of RET-MEN2A mediates activation of Akt (protein kinase B) and mitogen-activated protein kinase pathways leading to PC12 cell survival 21
Ras-mediated apoptosis of PC Cl 3 rat thyroid cells induced by RET/PTC oncogenes 21
null 21
Ret-mediated mitogenesis requires Src kinase activity. 21
CXC chemokine receptor 4 immunodetection in the follicular variant of papillary thyroid carcinoma: comparison to galectin-3 and hector battifora mesothelial cell-1. 21
The ret/ptc oncogene is activated in familial adenomatous polyposis-associated thyroid papillary carcinomas. 20
Protein kinase Calpha activation by RET: evidence for a negative feedback mechanism controlling RET tyrosine kinase 20
PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas. 20
RET\PTC activation in human thyroid carcinomas 20
Expression of the RET/PTC1 oncogene impairs the activity of TTF-1 and Pax-8 thyroid transcription factors. 20
Protein kinase Calpha activation by RET: evidence for a negative feedback mechanism controlling RET tyrosine kinase. 19
Ret-mediated mitogenesis requires Src kinase activity 19
The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway. 19
The docking protein FRS2 links RET and its oncogenic forms with the RAS/MAPK cascade. 19
null 19
HUMAN N-ras, TRK-T1, AND RET/PTC3 ONCOGENES, DRIVEN BY A THYROGLOBULIN PROMOTER, DIFFERENTLY AFFECT THE EXPRESSION OF DIFFERENTIATION MARKERS AND THE PROLIFERATION OF THYROID EPITHELIAL CELLS. 19
Molecular mechanisms of RET activation in human neoplasia 19
ROLES OF MAST CELLS AND THEIR MEDIATORS IN HUMAN THYROID CARCINOMAS 19
Mast cells play (a) protumorigenic roles in human thyroid cancer. 19
Tyrosine 1062 of RET-MEN2A mediates activation of Akt(PKB) and MAPK pathways leading to PC12 cell survival 18
Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2). 18
Totale 3.665
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Categoria #
all - tutte 15.464
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 15.464
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201912 0 0 0 0 0 0 0 0 0 0 2 10
2019/2020522 155 9 53 13 63 5 5 18 13 34 60 94
2020/2021667 22 55 80 54 71 71 66 47 69 23 89 20
2021/2022742 22 3 4 9 13 24 19 21 149 32 151 295
2022/20231.026 155 64 14 102 101 120 12 99 193 89 54 23
2023/2024524 27 70 95 69 44 49 30 109 13 18 0 0
Totale 4.290