MELILLO, ROSA MARINA

MELILLO, ROSA MARINA  

Dipartimento di Medicina molecolare e Biotecnologie mediche  

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The TRK and RET tyrosine kinase oncogenes cooperate with ras in the neoplastic transformation of a rat thyroid epithelial cell line. 1.1 Articolo in rivista 1993 Santoro, Massimo; Melillo, ROSA MARINA; Grieco, M.; Berlingieri, M. T.; Vecchio, Giancarlo; Fusco, Alfredo
Only the substitution of methionine 918 with a threonine and not with other residues activates RET transforming potential 1.1 Articolo in rivista 1997 Cirafici, Am; Salvatore, G; DE VITA, G; Carlomagno, Francesca; Dathan, Na; Visonti, R; Melillo, ROSA MARINA; Fusco, Alfredo; Santoro, M.
Ret-mediated mitogenesis requires Src kinase activity 1.1 Articolo in rivista 1999 Melillo, ROSA MARINA; Barone, Mv; Lupoli, G; Cirafici, Am; Carlomagno, Francesca; Visconti, R; Matoskova, B; DI FIORE, Pp; Vecchio, G; Fusco, Alfredo; Santoro, M.
Molecular biology of the MEN2 gene 1.1 Articolo in rivista 1998 Santoro, M; Melillo, ROSA MARINA; Carlomagno, Francesca; Visconti, R; DE VITA, Gabriella; Salvatore, G; Lupoli, G; Fusco, Alfredo; Vecchio, G.
Molecular heterogeneity of RET loss of function in Hirschsprung's disease 1.1 Articolo in rivista 1996 Carlomagno, Francesca; DE VITA, Gabriella; Berlingieri, Mt; DE FRANCISCIS, V; Melillo, ROSA MARINA; Colantuoni, V; Kraus, Mh; DI FIORE, Pp; Fusco, Alfredo; Santoro, M.
Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2) 1.1 Articolo in rivista 2003 Carlomagno, Francesca; Vitagliano, D; Guida, T; Basolo, F; Castellone, Md; Melillo, ROSA MARINA; Fusco, Alfredo; Santoro, Massimo
Tyrosine 1062 of RET-MEN2A mediates activation of Akt (protein kinase B) and mitogen-activated protein kinase pathways leading to PC12 cell survival 1.1 Articolo in rivista 2000 DE VITA, Gabriella; Melillo, ROSA MARINA; Carlomagno, Francesca; Visconti, R; Castellone, Md; Bellacosa, A; Billaud, M; Fusco, Alfredo; Tsichlis, Pn; Santoro, M.
Signalling of the Ret receptor tyrosine kinase through the c-Jun N-terminal Protein Kinases (JNKs): evidence for a divergence of the ERKs and JNKs pathways induced by Ret 1.1 Articolo in rivista 1998 Chiariello, M; Visconti, R; Carlomagno, Francesca; Melillo, ROSA MARINA; Bucci, C; DE FRANCISCIS, V; Fox, Gm; Jing, S; Coso, Om; Gutkind, Sj; Fusco, Alfredo; Santoro, M.
Molecular defects in thyroid carcinomas: role of the RET oncogene in thyroid neoplastic transformation. 1.1 Articolo in rivista 1995 Santoro, Massimo; M., Grieco; Melillo, ROSA MARINA; Fusco, Alfredo; Vecchio, Giancarlo
Molecular mechanisms of RET activation in human neoplasia. 1.1 Articolo in rivista 1999 Santoro, Massimo; Carlomagno, Francesca; Melillo, ROSA MARINA; M., Billaud; Vecchio, Giancarlo; Fusco, Alfredo
The different RET-activating capability of mutations of cysteine 620 or cysteine 634 correlates with the multiple endocrine neoplasia type 2 disease phenotype. 1.1 Articolo in rivista 1997 Carlomagno, Francesca; G., Salvatore; A. M., Cirafici; DE VITA, Gabriella; Melillo, ROSA MARINA; V. d., Franciscis; M., Billaud; Fusco, Alfredo; Santoro, Massimo
RET/PTC1 oncogene signaling in PC Cl 3 thyroid cells requires the small GTP-binding protein Rho. 1.1 Articolo in rivista 2001 Barone, MARIA VITTORIA; Sepe, L; Melillo, ROSA MARINA; Mineo, A; Santelli, G; Monaco, C; Castellone, Md; Tramontano, Donatella; Fusco, Alfredo; Santoro, Massimo
The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway. 1.1 Articolo in rivista 2002 Pelicci, G; Troglio, F; Bodini, A; Melillo, ROSA MARINA; Pettirossi, V; Coda, L; DE GIUSEPPE, A; Santoro, Massimo; Pelicci, Pg
Molecular heterogeneity of RET loss of function in Hirschsprung's disease. 1.1 Articolo in rivista 1996 Carlomagno, F; DE VITA, G; Berlingieri, Mt; DE FRANCISCIS, V; Melillo, ROSA MARINA; Colantuoni, V; Kraus, Mh; DI FIORE, Pp; Fusco, Alfredo; M., Santoro
The Insulin Receptor Substrate (IRS)-1 recruits Phosphatidylinositol 3-Kinase to Ret: evidence for a competition between Shc and IRS-1 for the binding to Ret. 1.1 Articolo in rivista 2001 Melillo, ROSA MARINA; Carlomagno, Francesca; DE VITA, Gabriella; Formisano, Pietro; Vecchio, Giancarlo; Fusco, Alfredo; Billaud, M.; Santoro, Massimo
Potent mitogenicity of the RET/PTC3 oncogene correlates with its prevalence in tall-cell variant of papillary thyroid carcinoma 1.1 Articolo in rivista 2002 F., Basolo; R., Giannini; C., Monaco; Melillo, ROSA MARINA; Carlomagno, Francesca; M., Pancrazi; G., Salvatore; G., Chiappetta; F., Pacini; R., Elisei; P., Miccoli; A., Pinchera; Fusco, Alfredo; Santoro, Massimo
Molecular mechanisms of RET activation in human cancer 2.1 Contributo in volume (Capitolo o Saggio) 2002 Santoro, Massimo; Melillo, ROSA MARINA; Carlomagno, F; Fusco, Alfredo; Vecchio, Giancarlo
The docking protein FRS2 links RET and its oncogenic forms with the RAS/MAPK cascade. 1.1 Articolo in rivista 2001 Melillo, ROSA MARINA; Santoro, Massimo; S. H., Ong; M., Billaud; Fusco, Alfredo; J., Schlessinger; I., Lax
Ret-mediated mitogenesis requires Src kinase activity. 1.1 Articolo in rivista 1999 Melillo, ROSA MARINA; Barone, Mv; Lupoli, G; Cirafici, Am; Carlomagno, F; Visconti, R; Matoskova, B; DI FIORE, Pp; Vecchio, G; Fusco, Alfredo; Santoro, Massimo
Genetic Alterations in differentiated thyroid cancer:what can be expected for gene expression profiling of thyroid carcinomas 1.1 Articolo in rivista 2003 Santoro, Massimo; Melillo, ROSA MARINA; Carlomagno, Francesca; Castellone, MARIA DOMENICA; Vitagliano, Donata; Guida, Teresa; Vecchio, Giancarlo; Fusco, Alfredo