IRIS
MEDINA SANABRIA, Diego Luis
 Distribuzione geografica
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Continente #
AS - Asia 3.065
NA - Nord America 2.499
EU - Europa 2.284
SA - Sud America 452
AF - Africa 89
OC - Oceania 11
Continente sconosciuto - Info sul continente non disponibili 1
Totale 8.401
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Nazione #
US - Stati Uniti d'America 2.398
SG - Singapore 1.380
RU - Federazione Russa 868
IT - Italia 700
CN - Cina 551
VN - Vietnam 516
BR - Brasile 386
HK - Hong Kong 265
DE - Germania 141
NL - Olanda 133
FR - Francia 128
GB - Regno Unito 57
CA - Canada 55
IN - India 54
FI - Finlandia 53
BD - Bangladesh 48
UA - Ucraina 48
JP - Giappone 47
KR - Corea 45
IE - Irlanda 33
CI - Costa d'Avorio 29
ZA - Sudafrica 25
TR - Turchia 24
AT - Austria 23
AR - Argentina 22
MX - Messico 22
SE - Svezia 22
PL - Polonia 21
PH - Filippine 20
IQ - Iraq 17
ES - Italia 14
EC - Ecuador 13
ID - Indonesia 13
SA - Arabia Saudita 10
TH - Thailandia 10
TW - Taiwan 9
AU - Australia 8
CO - Colombia 8
MA - Marocco 7
AE - Emirati Arabi Uniti 6
BG - Bulgaria 6
DZ - Algeria 6
PY - Paraguay 6
UZ - Uzbekistan 6
PK - Pakistan 5
AL - Albania 4
BO - Bolivia 4
CH - Svizzera 4
CR - Costa Rica 4
CZ - Repubblica Ceca 4
IR - Iran 4
JO - Giordania 4
MY - Malesia 4
NP - Nepal 4
PE - Perù 4
VE - Venezuela 4
AM - Armenia 3
BE - Belgio 3
BY - Bielorussia 3
CL - Cile 3
CY - Cipro 3
ET - Etiopia 3
HN - Honduras 3
KE - Kenya 3
NI - Nicaragua 3
SY - Repubblica araba siriana 3
TN - Tunisia 3
BF - Burkina Faso 2
BZ - Belize 2
DO - Repubblica Dominicana 2
EG - Egitto 2
GR - Grecia 2
IL - Israele 2
JM - Giamaica 2
KG - Kirghizistan 2
LB - Libano 2
LT - Lituania 2
MD - Moldavia 2
NG - Nigeria 2
OM - Oman 2
PS - Palestinian Territory 2
PT - Portogallo 2
SI - Slovenia 2
TT - Trinidad e Tobago 2
UY - Uruguay 2
VC - Saint Vincent e Grenadine 2
AD - Andorra 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
CG - Congo 1
DK - Danimarca 1
EE - Estonia 1
GA - Gabon 1
GD - Grenada 1
GE - Georgia 1
GT - Guatemala 1
HR - Croazia 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
LI - Liechtenstein 1
Totale 8.387
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Città #
Singapore 660
San Jose 487
Hong Kong 254
Chandler 253
Ashburn 193
Moscow 182
Naples 155
Ho Chi Minh City 144
Beijing 143
Hanoi 120
Santa Clara 92
Hefei 83
Amsterdam 82
Los Angeles 74
Lauterbourg 72
The Dalles 59
Boston 55
Millbury 54
Napoli 50
Nanjing 47
Lawrence 43
Des Moines 42
Frankfurt am Main 40
Tokyo 40
New York 36
Council Bluffs 33
Buffalo 30
Nuremberg 30
São Paulo 30
Da Nang 28
Chicago 25
Princeton 25
Redondo Beach 25
Haiphong 24
Munich 23
Ottawa 23
Rome 23
Wilmington 23
Dallas 22
Milan 21
Seoul 19
Orem 18
Belo Horizonte 17
Johannesburg 17
Rio de Janeiro 16
Helsinki 14
Warsaw 14
Atlanta 13
Falkenstein 13
Nanchang 12
Chennai 10
Hải Dương 10
Montreal 10
Seattle 10
Turku 10
Washington 10
Baghdad 9
Jacksonville 9
Lappeenranta 9
London 9
Vienna 9
Can Tho 8
Düsseldorf 8
Poplar 8
Porto Alegre 8
San Francisco 8
Shanghai 8
Shenyang 8
Toronto 8
Brasília 7
Cape Town 7
Fairfield 7
Houston 7
Jiaxing 7
Memphis 7
Paris 7
Seo-gu 7
Bangkok 6
Biên Hòa 6
Brooklyn 6
Casoria 6
Changsha 6
Dearborn 6
Denver 6
Dhaka 6
Goiânia 6
Hebei 6
Jeddah 6
Manchester 6
Mexico City 6
Mumbai 6
Padova 6
Santa Maria 6
Stockholm 6
Tashkent 6
Ankara 5
Campinas 5
Canegrate 5
Charlotte 5
Dublin 5
Totale 4.356
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Nome #
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 632
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) 272
miR-218 Promotes Dopaminergic Differentiation and Controls Neuron Excitability and Neurotransmitter Release through the Regulation of a Synaptic-Related Genes Network. 198
Light-responsive microRNA miR-211 targets Ezrin to modulate lysosomal biogenesis and retinal cell clearance 180
Activation of the transcription factor EB rescues lysosomal abnormalities in cystinotic kidney cells 169
A reverse-engineering approach to dissect post-translational modulators of transcription factor's activity from transcriptional data 159
FGF signalling regulates bone growth through autophagy 159
Lysosomal calcium signalling regulates autophagy through calcineurin and ​TFEB 158
EGR1 drives cell proliferation by directly stimulating TFEB transcription in response to starvation 149
Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL 139
Correction of oxidative stress enhances enzyme replacement therapy in Pompe disease 137
High-Throughput Functional Analysis Distinguishes Pathogenic, Nonpathogenic, and Compensatory Transcriptional Changes in Neurodegeneration 133
TFEB and the CLEAR network. 128
Regional- and age-dependent reduction in trkB receptor expression in the hippocampus is associated with altered spine morphologies 126
mTOR-dependent phosphorylation controls TFEB nuclear export 125
A Gene Network Regulating Lysosomal Biogenesis and Function 124
Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders 123
Fluoxetine ameliorates mucopolysaccharidosis type IIIA 123
The activity of Sac1 across ER-TGN contact sites requires the four-phosphate-adaptor-protein-1 120
Mechanism of TrkB-mediated hippocampal long-term potentiation 120
Current methods to analyse lysosome morphology, positioning, motility and function 120
NF-κB Activity Initiates Human ESC-Derived Neural Progenitor Cell Differentiation by Inducing a Metabolic Maturation Program 117
A Block of Autophagy in Lysosomal Storage Disorders 116
Methods to Monitor and Manipulate TFEB Activity During Autophagy 116
TrkB regulates neocortex formation through the Shc/PLCgamma-mediated control of neuronal migration 116
TRPML1: The Ca(2+)retaker of the lysosome 115
In vitro high-content screening reveals miR-429 as a protective molecule in photoreceptor degeneration 111
Lysosomotropic Drugs: Pharmacological Tools to Study Lysosomal Function 111
TFEB-mediated increase in peripheral lysosomes regulates store-operated calcium entry 110
Automatic identification of small molecules that promote cell conversion and reprogramming 110
TFEB Modulates p21/WAF1/CIP1 during the DNA Damage Response 109
SBDS-Deficient Cells Have an Altered Homeostatic Equilibrium due to Translational Inefficiency Which Explains their Reduced Fitness and Provides a Logical Framework for Intervention 108
Clinical challenges and future therapeutic approaches for neuronal ceroid lipofuscinosis 108
Transcriptional activation of lysosomal exocytosis promotes cellular clearance. 107
Sestrin2 drives ER-phagy in response to protein misfolding 106
Fingolimod Phosphate Inhibits Astrocyte Inflammatory Activity in Mucolipidosis IV 106
RhoA activation promotes transformation and loss of thyroid cell differentiation interfering with thyroid transcription factor-1 activity 102
c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder 102
TRPML-1 Dysfunction and Renal Tubulopathy in Mucolipidosis Type IV 101
TFEB Links Autophagy to Lysosomal Biogenesis. 101
Repurposing of tamoxifen ameliorates CLN3 and CLN7 disease phenotype 99
Drug repurposing in rare diseases: An integrative study of drug screening and transcriptomic analysis in nephropathic cystinosis 99
Loss of the batten disease protein CLN3 leads to mis-trafficking of M6PR and defective autophagic-lysosomal reformation 98
Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells 95
High-Throughput Screening Identifies Kinase Inhibitors That Increase Dual Adeno-Associated Viral Vector Transduction in Vitro and in Mouse Retina 93
TFEB controls syncytiotrophoblast formation and hormone production in placenta 92
TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann-Pick type C1, and Batten disease 91
Investigation on lysosomal accumulation by a quantitative analysis of 2D phase-maps in digital holography microscopy 89
Comparing structural and transcriptional drug networks reveals signatures of drug activity and toxicity in transcriptional responses 80
Autophagy modulator scoring system: a user-friendly tool for quantitative analysis of methodological integrity of chemical autophagy modulator studies 78
TRPML1-/TFEB-dependent regulation of lysosomal exocytosis 75
gene2drug: a Computational Tool for Pathway-based Rational Drug Repositioning 74
The Regulation of MiTF/TFE Transcription Factors Across Model Organisms: from Brain Physiology to Implication for Neurodegeneration 73
Aberrant upregulation of the glycolytic enzyme PFKFB3 in CLN7 neuronal ceroid lipofuscinosis 72
Signals from the lysosome: a control centre for cellular clearance and energy metabolism. 71
TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy 70
The rapidly evolving view of lysosomal storage diseases 70
Brain Disorders Due to Lysomal Dysfunction 67
Thyrotropin-dependent proliferation of in vitro rat thyroid cell systems 67
Somatostatin is expressed in FRTL-5 thyroid cells and prevents thyrotropin-mediated down-regulation of the cyclin-dependent kinase inhibitor p27kip1 67
The phytoestrogen genistein modulates lysosomal metabolism and Transcription Factor EB (TFEB) activation. 66
TFEB variants and uses thereof 65
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB. 64
TRPML1 and TFEB, an Intimate Affair 63
A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition 63
Ca2+-dependent regulation of TFEB and lysosomal function 63
Activation of Ca2+ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy in flies 60
The MDM2 oncoprotein promotes apoptosis in p53-deficient human medullary thyroid carcinoma cells 59
Synthetic lethality screening identifies fda-approved drugs that overcome atp7b-mediated tolerance of tumor cells to cisplatin 58
Antagonistic effect of cyclin-dependent kinases and a calcium-dependent phosphatase on polyglutamine-expanded androgen receptor toxic gain of function 55
High-content drug screening for rare diseases 55
Multi-OMICs analysis on tridimensional fibroblast spheroids to model vascular Ehlers-Danlos syndrome pathogenesis 55
TFEB phosphorylation inhibitors and uses thereof 54
Lysosomal calcium and autophagy 54
Role of insulin and serum on thyrotropin regulation of thyroid transcription factor-1 and pax-8 genes expression in FRTL-5 thyroid cells 53
Pharmacological approaches to tackle NCLs 53
Cellular and Gene Expression Response to the Combination of Genistein and Kaempferol in the Treatment of Mucopolysaccharidosis Type I 52
Introduction of p53 induces cell-cycle arrest in p53-deficient human medullary-thyroid-carcinoma cells 48
Drug-Induced Reversible Lysosomal Changes Tracked in Live Cells by Holo-Tomographic Flow Cytometry 47
TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway 47
Somatostatin interferes with thyrotropin-induced G1-S transition mediated by cAMP-dependent protein kinase and phosphatidylinositol 3-kinase. Involvement of RhoA and cyclin E x cyclin-dependent kinase 2 complexes 46
Lysosomal calcium regulates autophagy. 30
Proteotoxic stress triggers TFEB- and TFE3-mediated autophagy and lysosomal biogenesis via non-canonical MTORC1 inactivation 25
GMPPB-CDG Results in Lysosomal Dysfunction and Acid Alpha-Glucosidase Deficiency 24
null 22
Totale 8.567
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Categoria #
all - tutte 25.720
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 25.720
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20215 0 0 0 0 0 0 0 0 0 0 0 5
2021/2022327 12 9 9 5 6 9 8 12 40 19 35 163
2022/2023601 76 60 14 37 70 64 8 62 80 85 33 12
2023/2024449 26 64 61 39 18 32 17 47 20 29 64 32
2024/20252.261 108 126 14 34 61 139 295 181 164 217 771 151
2025/20264.407 427 303 452 452 721 227 569 309 485 290 161 11
Totale 8.567