IRIS
MEDINA SANABRIA, Diego Luis
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
AS - Asia 3.111
NA - Nord America 2.811
EU - Europa 2.338
SA - Sud America 461
Continente sconosciuto - Info sul continente non disponibili 167
AF - Africa 89
OC - Oceania 11
Totale 8.988
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 2.676
SG - Singapore 1.381
RU - Federazione Russa 868
IT - Italia 738
CN - Cina 566
VN - Vietnam 517
BR - Brasile 390
HK - Hong Kong 266
DE - Germania 143
NL - Olanda 133
FR - Francia 130
CA - Canada 74
BD - Bangladesh 66
GB - Regno Unito 59
IN - India 55
FI - Finlandia 53
JP - Giappone 49
UA - Ucraina 49
KR - Corea 45
IE - Irlanda 34
CI - Costa d'Avorio 29
ZA - Sudafrica 25
MX - Messico 24
TR - Turchia 24
AT - Austria 23
AR - Argentina 22
SE - Svezia 22
PH - Filippine 21
PL - Polonia 21
ES - Italia 18
IQ - Iraq 17
EC - Ecuador 14
ID - Indonesia 13
CO - Colombia 11
SA - Arabia Saudita 11
TH - Thailandia 10
TW - Taiwan 9
AU - Australia 8
NP - Nepal 8
MA - Marocco 7
AE - Emirati Arabi Uniti 6
BG - Bulgaria 6
DZ - Algeria 6
NI - Nicaragua 6
PY - Paraguay 6
UZ - Uzbekistan 6
CR - Costa Rica 5
HN - Honduras 5
MY - Malesia 5
PK - Pakistan 5
AL - Albania 4
BO - Bolivia 4
CH - Svizzera 4
CL - Cile 4
CZ - Repubblica Ceca 4
IR - Iran 4
JM - Giamaica 4
JO - Giordania 4
PE - Perù 4
TT - Trinidad e Tobago 4
VE - Venezuela 4
AM - Armenia 3
BE - Belgio 3
BY - Bielorussia 3
CY - Cipro 3
ET - Etiopia 3
KE - Kenya 3
MD - Moldavia 3
SY - Repubblica araba siriana 3
TN - Tunisia 3
BB - Barbados 2
BF - Burkina Faso 2
BZ - Belize 2
DO - Repubblica Dominicana 2
EG - Egitto 2
GR - Grecia 2
GT - Guatemala 2
HR - Croazia 2
IL - Israele 2
KG - Kirghizistan 2
LB - Libano 2
LT - Lituania 2
NG - Nigeria 2
NO - Norvegia 2
OM - Oman 2
PS - Palestinian Territory 2
PT - Portogallo 2
SI - Slovenia 2
SK - Slovacchia (Repubblica Slovacca) 2
UY - Uruguay 2
VC - Saint Vincent e Grenadine 2
AD - Andorra 1
BA - Bosnia-Erzegovina 1
CG - Congo 1
DK - Danimarca 1
EE - Estonia 1
GA - Gabon 1
GD - Grenada 1
GE - Georgia 1
KZ - Kazakistan 1
Totale 8.807
Salva come PNG Salva come JPEG
Città #
Singapore 661
San Jose 515
Hong Kong 255
Chandler 253
Ashburn 237
Moscow 182
Naples 159
Beijing 145
Ho Chi Minh City 145
Hanoi 120
Santa Clara 104
Council Bluffs 85
Hefei 83
Amsterdam 82
Los Angeles 81
Lauterbourg 72
The Dalles 59
Boston 55
Millbury 54
Napoli 50
Nanjing 47
Des Moines 43
Lawrence 43
Tokyo 42
New York 41
Frankfurt am Main 40
São Paulo 33
Buffalo 30
Nuremberg 30
Da Nang 28
Chicago 26
Rome 26
Dallas 25
Princeton 25
Redondo Beach 25
Haiphong 24
Milan 23
Munich 23
Ottawa 23
Wilmington 23
Orem 19
Seoul 19
Belo Horizonte 17
Johannesburg 17
Rio de Janeiro 16
Atlanta 14
Helsinki 14
Warsaw 14
Falkenstein 13
Toronto 13
Nanchang 12
Seattle 12
Washington 12
Houston 11
Montreal 11
Chennai 10
Hải Dương 10
Jacksonville 10
San Francisco 10
Turku 10
Baghdad 9
Lappeenranta 9
London 9
Vienna 9
Brooklyn 8
Can Tho 8
Düsseldorf 8
Manchester 8
Memphis 8
Phoenix 8
Poplar 8
Porto Alegre 8
Shanghai 8
Shenyang 8
Brasília 7
Cape Town 7
Changsha 7
Fairfield 7
Jeddah 7
Jiaxing 7
Mexico City 7
Paris 7
Seo-gu 7
Bangkok 6
Biên Hòa 6
Casoria 6
Charlotte 6
Dearborn 6
Denver 6
Detroit 6
Dhaka 6
Goiânia 6
Hebei 6
Managua 6
Mumbai 6
Padova 6
Philadelphia 6
Richmond 6
Santa Maria 6
Stockholm 6
Totale 4.562
Salva come PNG Salva come JPEG
Nome #
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 674
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) 286
miR-218 Promotes Dopaminergic Differentiation and Controls Neuron Excitability and Neurotransmitter Release through the Regulation of a Synaptic-Related Genes Network. 202
Light-responsive microRNA miR-211 targets Ezrin to modulate lysosomal biogenesis and retinal cell clearance 183
Activation of the transcription factor EB rescues lysosomal abnormalities in cystinotic kidney cells 175
Lysosomal calcium signalling regulates autophagy through calcineurin and ​TFEB 165
FGF signalling regulates bone growth through autophagy 163
A reverse-engineering approach to dissect post-translational modulators of transcription factor's activity from transcriptional data 161
EGR1 drives cell proliferation by directly stimulating TFEB transcription in response to starvation 155
Correction of oxidative stress enhances enzyme replacement therapy in Pompe disease 147
Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL 143
High-Throughput Functional Analysis Distinguishes Pathogenic, Nonpathogenic, and Compensatory Transcriptional Changes in Neurodegeneration 138
TFEB and the CLEAR network. 137
Regional- and age-dependent reduction in trkB receptor expression in the hippocampus is associated with altered spine morphologies 132
mTOR-dependent phosphorylation controls TFEB nuclear export 131
A Gene Network Regulating Lysosomal Biogenesis and Function 130
Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders 130
Mechanism of TrkB-mediated hippocampal long-term potentiation 128
Sestrin2 drives ER-phagy in response to protein misfolding 126
Fluoxetine ameliorates mucopolysaccharidosis type IIIA 125
TRPML1: The Ca(2+)retaker of the lysosome 124
Automatic identification of small molecules that promote cell conversion and reprogramming 124
Current methods to analyse lysosome morphology, positioning, motility and function 123
Methods to Monitor and Manipulate TFEB Activity During Autophagy 122
The activity of Sac1 across ER-TGN contact sites requires the four-phosphate-adaptor-protein-1 122
TRPML-1 Dysfunction and Renal Tubulopathy in Mucolipidosis Type IV 120
TrkB regulates neocortex formation through the Shc/PLCgamma-mediated control of neuronal migration 120
NF-κB Activity Initiates Human ESC-Derived Neural Progenitor Cell Differentiation by Inducing a Metabolic Maturation Program 119
In vitro high-content screening reveals miR-429 as a protective molecule in photoreceptor degeneration 118
A Block of Autophagy in Lysosomal Storage Disorders 118
TFEB Modulates p21/WAF1/CIP1 during the DNA Damage Response 117
Lysosomotropic Drugs: Pharmacological Tools to Study Lysosomal Function 114
Clinical challenges and future therapeutic approaches for neuronal ceroid lipofuscinosis 114
SBDS-Deficient Cells Have an Altered Homeostatic Equilibrium due to Translational Inefficiency Which Explains their Reduced Fitness and Provides a Logical Framework for Intervention 113
TFEB-mediated increase in peripheral lysosomes regulates store-operated calcium entry 112
Transcriptional activation of lysosomal exocytosis promotes cellular clearance. 110
Fingolimod Phosphate Inhibits Astrocyte Inflammatory Activity in Mucolipidosis IV 110
Loss of the batten disease protein CLN3 leads to mis-trafficking of M6PR and defective autophagic-lysosomal reformation 107
c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder 106
RhoA activation promotes transformation and loss of thyroid cell differentiation interfering with thyroid transcription factor-1 activity 105
Drug repurposing in rare diseases: An integrative study of drug screening and transcriptomic analysis in nephropathic cystinosis 105
TFEB Links Autophagy to Lysosomal Biogenesis. 104
Repurposing of tamoxifen ameliorates CLN3 and CLN7 disease phenotype 104
Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells 98
TFEB controls syncytiotrophoblast formation and hormone production in placenta 97
High-Throughput Screening Identifies Kinase Inhibitors That Increase Dual Adeno-Associated Viral Vector Transduction in Vitro and in Mouse Retina 96
TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann-Pick type C1, and Batten disease 94
Investigation on lysosomal accumulation by a quantitative analysis of 2D phase-maps in digital holography microscopy 91
Autophagy modulator scoring system: a user-friendly tool for quantitative analysis of methodological integrity of chemical autophagy modulator studies 85
Comparing structural and transcriptional drug networks reveals signatures of drug activity and toxicity in transcriptional responses 81
Aberrant upregulation of the glycolytic enzyme PFKFB3 in CLN7 neuronal ceroid lipofuscinosis 77
gene2drug: a Computational Tool for Pathway-based Rational Drug Repositioning 76
TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy 76
TRPML1-/TFEB-dependent regulation of lysosomal exocytosis 76
The Regulation of MiTF/TFE Transcription Factors Across Model Organisms: from Brain Physiology to Implication for Neurodegeneration 75
Signals from the lysosome: a control centre for cellular clearance and energy metabolism. 73
The rapidly evolving view of lysosomal storage diseases 73
Brain Disorders Due to Lysomal Dysfunction 70
Thyrotropin-dependent proliferation of in vitro rat thyroid cell systems 68
Somatostatin is expressed in FRTL-5 thyroid cells and prevents thyrotropin-mediated down-regulation of the cyclin-dependent kinase inhibitor p27kip1 68
A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition 67
Ca2+-dependent regulation of TFEB and lysosomal function 67
TRPML1 and TFEB, an Intimate Affair 66
The phytoestrogen genistein modulates lysosomal metabolism and Transcription Factor EB (TFEB) activation. 66
TFEB variants and uses thereof 66
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB. 65
Activation of Ca2+ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy in flies 63
Synthetic lethality screening identifies fda-approved drugs that overcome atp7b-mediated tolerance of tumor cells to cisplatin 62
The MDM2 oncoprotein promotes apoptosis in p53-deficient human medullary thyroid carcinoma cells 60
Multi-OMICs analysis on tridimensional fibroblast spheroids to model vascular Ehlers-Danlos syndrome pathogenesis 60
High-content drug screening for rare diseases 58
Role of insulin and serum on thyrotropin regulation of thyroid transcription factor-1 and pax-8 genes expression in FRTL-5 thyroid cells 58
Lysosomal calcium and autophagy 58
Antagonistic effect of cyclin-dependent kinases and a calcium-dependent phosphatase on polyglutamine-expanded androgen receptor toxic gain of function 56
TFEB phosphorylation inhibitors and uses thereof 56
Cellular and Gene Expression Response to the Combination of Genistein and Kaempferol in the Treatment of Mucopolysaccharidosis Type I 55
Pharmacological approaches to tackle NCLs 54
Drug-Induced Reversible Lysosomal Changes Tracked in Live Cells by Holo-Tomographic Flow Cytometry 50
Introduction of p53 induces cell-cycle arrest in p53-deficient human medullary-thyroid-carcinoma cells 50
TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway 49
Somatostatin interferes with thyrotropin-induced G1-S transition mediated by cAMP-dependent protein kinase and phosphatidylinositol 3-kinase. Involvement of RhoA and cyclin E x cyclin-dependent kinase 2 complexes 47
Proteotoxic stress triggers TFEB- and TFE3-mediated autophagy and lysosomal biogenesis via non-canonical MTORC1 inactivation 33
Lysosomal calcium regulates autophagy. 32
GMPPB-CDG Results in Lysosomal Dysfunction and Acid Alpha-Glucosidase Deficiency 32
null 22
Totale 8.988
Salva come PNG Salva come JPEG
Categoria #
all - tutte 28.791
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 28.791
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022315 0 9 9 5 6 9 8 12 40 19 35 163
2022/2023601 76 60 14 37 70 64 8 62 80 85 33 12
2023/2024449 26 64 61 39 18 32 17 47 20 29 64 32
2024/20252.261 108 126 14 34 61 139 295 181 164 217 771 151
2025/20264.506 427 303 452 452 721 227 569 309 485 290 161 110
2026/2027322 134 188 0 0 0 0 0 0 0 0 0 0
Totale 8.988