IRIS
MEDINA SANABRIA, Diego Luis
 Distribuzione geografica
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Continente #
NA - Nord America 937
EU - Europa 542
AS - Asia 138
AF - Africa 30
Totale 1.647
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Nazione #
US - Stati Uniti d'America 912
IT - Italia 326
CN - Cina 128
NL - Olanda 74
UA - Ucraina 36
CI - Costa d'Avorio 29
IE - Irlanda 29
CA - Canada 24
FI - Finlandia 22
DE - Germania 15
SE - Svezia 14
FR - Francia 12
GB - Regno Unito 6
ES - Italia 2
JP - Giappone 2
KR - Corea 2
BE - Belgio 1
BG - Bulgaria 1
BZ - Belize 1
EE - Estonia 1
HR - Croazia 1
IN - India 1
IQ - Iraq 1
MD - Moldavia 1
NG - Nigeria 1
PL - Polonia 1
SA - Arabia Saudita 1
SG - Singapore 1
TW - Taiwan 1
VN - Vietnam 1
Totale 1.647
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Città #
Chandler 253
Amsterdam 73
Naples 71
Ashburn 60
Millbury 54
Napoli 50
Boston 48
Nanjing 45
Lawrence 43
Des Moines 41
Beijing 33
Princeton 25
Wilmington 23
Ottawa 22
Nanchang 12
Milan 8
Rome 8
Shenyang 8
Washington 8
Fairfield 7
Jacksonville 7
Jiaxing 7
Los Angeles 7
Dearborn 6
Hebei 6
Houston 6
Padova 6
Canegrate 5
Casoria 4
Florence 4
Lappeenranta 4
Marsicovetere 4
Norwalk 4
San Jose 4
Siena 4
Tianjin 4
Bacoli 3
Bungay 3
Caserta 3
Changsha 3
Torino 3
Trecase 3
Turin 3
Avellino 2
Aversa 2
Aviano 2
Boardman 2
Capodrise 2
Chiusi 2
Ciampino 2
Dublin 2
Eboli 2
Forest Hills 2
Gorle 2
Gwanak-gu 2
Kronberg 2
Kunming 2
Monopoli 2
New York 2
Palma Campania 2
Qualiano 2
Saint-Fons 2
Salerno 2
Sezze 2
Shanghai 2
Venezia 2
Verona 2
Andover 1
Arzano 1
Baghdad 1
Belize City 1
Boscoreale 1
Brussels 1
Cambridge 1
Cardito 1
Casamicciola Terme 1
Chisinau 1
Como 1
Edinburgh 1
Falls Church 1
Forio 1
Fremont 1
Fuzhou 1
Hangzhou 1
Isola di Capo Rizzuto 1
Kent 1
Leipzig 1
Marano Di Napoli 1
Mercato San Severino 1
Montesarchio 1
Montréal 1
Mugnano Di Napoli 1
Noisy-le-sec 1
Nola 1
Omaha 1
Pompei 1
Pune 1
Redwood City 1
Regensburg 1
Rossano 1
Totale 1.076
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Nome #
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) 103
Light-responsive microRNA miR-211 targets Ezrin to modulate lysosomal biogenesis and retinal cell clearance 90
FGF signalling regulates bone growth through autophagy 57
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 54
Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders 44
Lysosomal calcium signalling regulates autophagy through calcineurin and ​TFEB 43
Activation of the transcription factor EB rescues lysosomal abnormalities in cystinotic kidney cells 42
The activity of Sac1 across ER-TGN contact sites requires the four-phosphate-adaptor-protein-1 40
A reverse-engineering approach to dissect post-translational modulators of transcription factor's activity from transcriptional data 39
A Block of Autophagy in Lysosomal Storage Disorders 36
Regional- and age-dependent reduction in trkB receptor expression in the hippocampus is associated with altered spine morphologies 36
Correction of oxidative stress enhances enzyme replacement therapy in Pompe disease 31
Comparing structural and transcriptional drug networks reveals signatures of drug activity and toxicity in transcriptional responses 30
mTOR-dependent phosphorylation controls TFEB nuclear export 30
EGR1 drives cell proliferation by directly stimulating TFEB transcription in response to starvation 29
Methods to Monitor and Manipulate TFEB Activity During Autophagy 29
Clinical challenges and future therapeutic approaches for neuronal ceroid lipofuscinosis 29
Automatic identification of small molecules that promote cell conversion and reprogramming 29
Current methods to analyse lysosome morphology, positioning, motility and function 29
The rapidly evolving view of lysosomal storage diseases 28
A Gene Network Regulating Lysosomal Biogenesis and Function 27
TRPML1-/TFEB-dependent regulation of lysosomal exocytosis 26
Fingolimod Phosphate Inhibits Astrocyte Inflammatory Activity in Mucolipidosis IV 26
c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder 26
Ca2+-dependent regulation of TFEB and lysosomal function 25
TRPML1: The Ca(2+)retaker of the lysosome 25
Signals from the lysosome: a control centre for cellular clearance and energy metabolism. 24
TFEB and the CLEAR network. 24
Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL 24
Mechanism of TrkB-mediated hippocampal long-term potentiation 24
Somatostatin is expressed in FRTL-5 thyroid cells and prevents thyrotropin-mediated down-regulation of the cyclin-dependent kinase inhibitor p27kip1 24
TFEB Modulates p21/WAF1/CIP1 during the DNA Damage Response 24
TFEB Links Autophagy to Lysosomal Biogenesis. 23
Lysosomotropic Drugs: Pharmacological Tools to Study Lysosomal Function 23
Autophagy modulator scoring system: a user-friendly tool for quantitative analysis of methodological integrity of chemical autophagy modulator studies 23
null 22
RhoA activation promotes transformation and loss of thyroid cell differentiation interfering with thyroid transcription factor-1 activity 22
TrkB regulates neocortex formation through the Shc/PLCgamma-mediated control of neuronal migration 22
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB. 21
Brain Disorders Due to Lysomal Dysfunction 21
gene2drug: a Computational Tool for Pathway-based Rational Drug Repositioning 21
NF-κB Activity Initiates Human ESC-Derived Neural Progenitor Cell Differentiation by Inducing a Metabolic Maturation Program 21
SBDS-Deficient Cells Have an Altered Homeostatic Equilibrium due to Translational Inefficiency Which Explains their Reduced Fitness and Provides a Logical Framework for Intervention 21
Thyrotropin-dependent proliferation of in vitro rat thyroid cell systems 20
High-Throughput Functional Analysis Distinguishes Pathogenic, Nonpathogenic, and Compensatory Transcriptional Changes in Neurodegeneration 20
Drug repurposing in rare diseases: An integrative study of drug screening and transcriptomic analysis in nephropathic cystinosis 19
A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition 18
Role of insulin and serum on thyrotropin regulation of thyroid transcription factor-1 and pax-8 genes expression in FRTL-5 thyroid cells 18
Aberrant upregulation of the glycolytic enzyme PFKFB3 in CLN7 neuronal ceroid lipofuscinosis 18
The Regulation of MiTF/TFE Transcription Factors Across Model Organisms: from Brain Physiology to Implication for Neurodegeneration 18
TFEB-mediated increase in peripheral lysosomes regulates store-operated calcium entry 17
High-Throughput Screening Identifies Kinase Inhibitors That Increase Dual Adeno-Associated Viral Vector Transduction in Vitro and in Mouse Retina 17
TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy 17
The MDM2 oncoprotein promotes apoptosis in p53-deficient human medullary thyroid carcinoma cells 17
Fluoxetine ameliorates mucopolysaccharidosis type IIIA 17
The phytoestrogen genistein modulates lysosomal metabolism and Transcription Factor EB (TFEB) activation. 16
Transcriptional activation of lysosomal exocytosis promotes cellular clearance. 15
Introduction of p53 induces cell-cycle arrest in p53-deficient human medullary-thyroid-carcinoma cells 15
TFEB variants and uses thereof 15
Cellular and Gene Expression Response to the Combination of Genistein and Kaempferol in the Treatment of Mucopolysaccharidosis Type I 15
Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells 11
miR-218 Promotes Dopaminergic Differentiation and Controls Neuron Excitability and Neurotransmitter Release through the Regulation of a Synaptic-Related Genes Network. 10
High-content drug screening for rare diseases 10
Repurposing of tamoxifen ameliorates CLN3 and CLN7 disease phenotype 10
TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann-Pick type C1, and Batten disease 9
TRPML1 and TFEB, an Intimate Affair 9
Loss of the batten disease protein CLN3 leads to mis-trafficking of M6PR and defective autophagic-lysosomal reformation 9
Somatostatin interferes with thyrotropin-induced G1-S transition mediated by cAMP-dependent protein kinase and phosphatidylinositol 3-kinase. Involvement of RhoA and cyclin E x cyclin-dependent kinase 2 complexes 8
TFEB phosphorylation inhibitors and uses thereof 8
TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway 7
Lysosomal calcium and autophagy 7
Antagonistic effect of cyclin-dependent kinases and a calcium-dependent phosphatase on polyglutamine-expanded androgen receptor toxic gain of function 6
Pharmacological approaches to tackle NCLs 6
Synthetic lethality screening identifies fda-approved drugs that overcome atp7b-mediated tolerance of tumor cells to cisplatin 6
Investigation on lysosomal accumulation by a quantitative analysis of 2D phase-maps in digital holography microscopy 1
Activation of Ca2+ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy in flies 1
Lysosomal calcium regulates autophagy. 1
Totale 1.798
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Categoria #
all - tutte 7.031
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 7.031
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201943 0 0 0 0 0 0 0 0 0 6 33 4
2019/2020240 91 3 4 1 11 3 16 4 28 28 34 17
2020/2021106 3 8 16 9 8 9 13 8 14 5 8 5
2021/2022327 12 9 9 5 6 9 8 12 40 19 35 163
2022/2023601 76 60 14 37 70 64 8 62 80 85 33 12
2023/2024348 26 64 61 39 18 32 17 47 20 24 0 0
Totale 1.798