IRIS
MEDINA SANABRIA, Diego Luis
 Distribuzione geografica
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Continente #
AS - Asia 2.359
EU - Europa 2.048
NA - Nord America 1.716
SA - Sud America 424
AF - Africa 76
OC - Oceania 7
Totale 6.630
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Nazione #
US - Stati Uniti d'America 1.636
SG - Singapore 1.296
RU - Federazione Russa 867
IT - Italia 598
CN - Cina 482
BR - Brasile 370
HK - Hong Kong 243
VN - Vietnam 154
DE - Germania 121
NL - Olanda 119
FR - Francia 53
FI - Finlandia 52
GB - Regno Unito 52
CA - Canada 48
UA - Ucraina 44
KR - Corea 35
IN - India 33
IE - Irlanda 32
CI - Costa d'Avorio 29
AT - Austria 22
SE - Svezia 22
ZA - Sudafrica 22
PL - Polonia 21
TR - Turchia 21
AR - Argentina 18
BD - Bangladesh 17
MX - Messico 15
ES - Italia 13
EC - Ecuador 11
IQ - Iraq 10
JP - Giappone 10
ID - Indonesia 9
CO - Colombia 7
MA - Marocco 7
AE - Emirati Arabi Uniti 6
BG - Bulgaria 6
PY - Paraguay 5
SA - Arabia Saudita 5
AL - Albania 4
AU - Australia 4
IR - Iran 4
PE - Perù 4
BE - Belgio 3
BO - Bolivia 3
CL - Cile 3
CY - Cipro 3
CZ - Repubblica Ceca 3
HN - Honduras 3
NP - Nepal 3
PH - Filippine 3
PK - Pakistan 3
SY - Repubblica araba siriana 3
TH - Thailandia 3
TN - Tunisia 3
UZ - Uzbekistan 3
AM - Armenia 2
BF - Burkina Faso 2
BY - Bielorussia 2
BZ - Belize 2
CR - Costa Rica 2
ET - Etiopia 2
IL - Israele 2
KE - Kenya 2
LT - Lituania 2
NG - Nigeria 2
PS - Palestinian Territory 2
TT - Trinidad e Tobago 2
TW - Taiwan 2
UY - Uruguay 2
VC - Saint Vincent e Grenadine 2
AD - Andorra 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
CG - Congo 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
EE - Estonia 1
GA - Gabon 1
GD - Grenada 1
GE - Georgia 1
GR - Grecia 1
GT - Guatemala 1
HR - Croazia 1
JO - Giordania 1
KZ - Kazakistan 1
MD - Moldavia 1
MY - Malesia 1
NC - Nuova Caledonia 1
NI - Nicaragua 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PG - Papua Nuova Guinea 1
PR - Porto Rico 1
PT - Portogallo 1
RE - Reunion 1
RO - Romania 1
SC - Seychelles 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 6.626
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Città #
Singapore 591
Chandler 253
Hong Kong 238
Moscow 182
Naples 147
Beijing 134
Ashburn 131
Hefei 83
Santa Clara 82
Amsterdam 78
Los Angeles 64
Boston 55
Millbury 54
Napoli 50
Ho Chi Minh City 48
Nanjing 46
Lawrence 43
Des Moines 41
San Jose 39
Hanoi 36
Nuremberg 29
São Paulo 29
Buffalo 28
New York 25
Princeton 25
Redondo Beach 25
Munich 23
Ottawa 23
Wilmington 23
Chicago 22
Frankfurt am Main 21
Rome 21
Dallas 17
Milan 17
Seoul 17
The Dalles 17
Johannesburg 16
Belo Horizonte 15
Rio de Janeiro 15
Helsinki 14
Warsaw 14
Falkenstein 13
Nanchang 12
Orem 10
Seattle 10
Turku 10
Washington 10
Jacksonville 9
Lappeenranta 9
Montreal 9
Atlanta 8
Düsseldorf 8
Haiphong 8
London 8
Poplar 8
Porto Alegre 8
Shanghai 8
Shenyang 8
Tokyo 8
Vienna 8
Brasília 7
Fairfield 7
Houston 7
Jiaxing 7
Seo-gu 7
Biên Hòa 6
Cape Town 6
Casoria 6
Changsha 6
Da Nang 6
Dearborn 6
Goiânia 6
Hebei 6
Padova 6
Santa Maria 6
Stockholm 6
Toronto 6
Brooklyn 5
Campinas 5
Canegrate 5
Chennai 5
Denver 5
Elk Grove Village 5
Mexico City 5
Mumbai 5
Paris 5
Phoenix 5
San Francisco 5
Turin 5
Ankara 4
Asunción 4
Baghdad 4
Busan 4
Casablanca 4
Caxias do Sul 4
Dhaka 4
Dublin 4
Florence 4
Guayaquil 4
Ha Long 4
Totale 3.214
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Nome #
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 405
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) 235
Light-responsive microRNA miR-211 targets Ezrin to modulate lysosomal biogenesis and retinal cell clearance 166
miR-218 Promotes Dopaminergic Differentiation and Controls Neuron Excitability and Neurotransmitter Release through the Regulation of a Synaptic-Related Genes Network. 165
Activation of the transcription factor EB rescues lysosomal abnormalities in cystinotic kidney cells 146
FGF signalling regulates bone growth through autophagy 137
A reverse-engineering approach to dissect post-translational modulators of transcription factor's activity from transcriptional data 133
Lysosomal calcium signalling regulates autophagy through calcineurin and ​TFEB 126
EGR1 drives cell proliferation by directly stimulating TFEB transcription in response to starvation 121
Correction of oxidative stress enhances enzyme replacement therapy in Pompe disease 114
Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders 108
TFEB and the CLEAR network. 107
A Gene Network Regulating Lysosomal Biogenesis and Function 106
Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL 106
Regional- and age-dependent reduction in trkB receptor expression in the hippocampus is associated with altered spine morphologies 104
mTOR-dependent phosphorylation controls TFEB nuclear export 102
The activity of Sac1 across ER-TGN contact sites requires the four-phosphate-adaptor-protein-1 102
Fluoxetine ameliorates mucopolysaccharidosis type IIIA 102
A Block of Autophagy in Lysosomal Storage Disorders 100
NF-κB Activity Initiates Human ESC-Derived Neural Progenitor Cell Differentiation by Inducing a Metabolic Maturation Program 99
Automatic identification of small molecules that promote cell conversion and reprogramming 98
Clinical challenges and future therapeutic approaches for neuronal ceroid lipofuscinosis 96
TRPML1: The Ca(2+)retaker of the lysosome 96
Current methods to analyse lysosome morphology, positioning, motility and function 96
Methods to Monitor and Manipulate TFEB Activity During Autophagy 95
Sestrin2 drives ER-phagy in response to protein misfolding 93
TrkB regulates neocortex formation through the Shc/PLCgamma-mediated control of neuronal migration 93
Mechanism of TrkB-mediated hippocampal long-term potentiation 93
Fingolimod Phosphate Inhibits Astrocyte Inflammatory Activity in Mucolipidosis IV 91
Lysosomotropic Drugs: Pharmacological Tools to Study Lysosomal Function 91
TFEB Modulates p21/WAF1/CIP1 during the DNA Damage Response 90
TFEB Links Autophagy to Lysosomal Biogenesis. 89
TFEB-mediated increase in peripheral lysosomes regulates store-operated calcium entry 89
SBDS-Deficient Cells Have an Altered Homeostatic Equilibrium due to Translational Inefficiency Which Explains their Reduced Fitness and Provides a Logical Framework for Intervention 85
Transcriptional activation of lysosomal exocytosis promotes cellular clearance. 84
RhoA activation promotes transformation and loss of thyroid cell differentiation interfering with thyroid transcription factor-1 activity 84
High-Throughput Functional Analysis Distinguishes Pathogenic, Nonpathogenic, and Compensatory Transcriptional Changes in Neurodegeneration 84
c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder 82
Repurposing of tamoxifen ameliorates CLN3 and CLN7 disease phenotype 80
Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells 79
Loss of the batten disease protein CLN3 leads to mis-trafficking of M6PR and defective autophagic-lysosomal reformation 78
Drug repurposing in rare diseases: An integrative study of drug screening and transcriptomic analysis in nephropathic cystinosis 77
TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann-Pick type C1, and Batten disease 76
In vitro high-content screening reveals miR-429 as a protective molecule in photoreceptor degeneration 70
High-Throughput Screening Identifies Kinase Inhibitors That Increase Dual Adeno-Associated Viral Vector Transduction in Vitro and in Mouse Retina 70
Comparing structural and transcriptional drug networks reveals signatures of drug activity and toxicity in transcriptional responses 68
Investigation on lysosomal accumulation by a quantitative analysis of 2D phase-maps in digital holography microscopy 67
TFEB controls syncytiotrophoblast formation and hormone production in placenta 65
TRPML-1 Dysfunction and Renal Tubulopathy in Mucolipidosis Type IV 64
Signals from the lysosome: a control centre for cellular clearance and energy metabolism. 63
Autophagy modulator scoring system: a user-friendly tool for quantitative analysis of methodological integrity of chemical autophagy modulator studies 59
Aberrant upregulation of the glycolytic enzyme PFKFB3 in CLN7 neuronal ceroid lipofuscinosis 59
TRPML1-/TFEB-dependent regulation of lysosomal exocytosis 58
Somatostatin is expressed in FRTL-5 thyroid cells and prevents thyrotropin-mediated down-regulation of the cyclin-dependent kinase inhibitor p27kip1 58
gene2drug: a Computational Tool for Pathway-based Rational Drug Repositioning 57
The rapidly evolving view of lysosomal storage diseases 56
TRPML1 and TFEB, an Intimate Affair 54
The phytoestrogen genistein modulates lysosomal metabolism and Transcription Factor EB (TFEB) activation. 54
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB. 53
TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy 52
Ca2+-dependent regulation of TFEB and lysosomal function 52
TFEB variants and uses thereof 51
The Regulation of MiTF/TFE Transcription Factors Across Model Organisms: from Brain Physiology to Implication for Neurodegeneration 51
Brain Disorders Due to Lysomal Dysfunction 50
Thyrotropin-dependent proliferation of in vitro rat thyroid cell systems 48
A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition 47
Role of insulin and serum on thyrotropin regulation of thyroid transcription factor-1 and pax-8 genes expression in FRTL-5 thyroid cells 47
Activation of Ca2+ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy in flies 46
Antagonistic effect of cyclin-dependent kinases and a calcium-dependent phosphatase on polyglutamine-expanded androgen receptor toxic gain of function 46
The MDM2 oncoprotein promotes apoptosis in p53-deficient human medullary thyroid carcinoma cells 46
Synthetic lethality screening identifies fda-approved drugs that overcome atp7b-mediated tolerance of tumor cells to cisplatin 46
TFEB phosphorylation inhibitors and uses thereof 44
Introduction of p53 induces cell-cycle arrest in p53-deficient human medullary-thyroid-carcinoma cells 42
Pharmacological approaches to tackle NCLs 41
Lysosomal calcium and autophagy 41
High-content drug screening for rare diseases 40
Cellular and Gene Expression Response to the Combination of Genistein and Kaempferol in the Treatment of Mucopolysaccharidosis Type I 39
Multi-OMICs analysis on tridimensional fibroblast spheroids to model vascular Ehlers-Danlos syndrome pathogenesis 39
Somatostatin interferes with thyrotropin-induced G1-S transition mediated by cAMP-dependent protein kinase and phosphatidylinositol 3-kinase. Involvement of RhoA and cyclin E x cyclin-dependent kinase 2 complexes 38
TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway 33
Drug-Induced Reversible Lysosomal Changes Tracked in Live Cells by Holo-Tomographic Flow Cytometry 32
Lysosomal calcium regulates autophagy. 23
null 22
Totale 6.794
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Categoria #
all - tutte 21.911
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 21.911
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202153 0 0 0 0 0 0 13 8 14 5 8 5
2021/2022327 12 9 9 5 6 9 8 12 40 19 35 163
2022/2023601 76 60 14 37 70 64 8 62 80 85 33 12
2023/2024449 26 64 61 39 18 32 17 47 20 29 64 32
2024/20252.261 108 126 14 34 61 139 295 181 164 217 771 151
2025/20262.634 427 303 452 452 721 227 52 0 0 0 0 0
Totale 6.794