IRIS
ANNUNZIATO, LUCIO
 Distribuzione geografica
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Continente #
AS - Asia 16.131
NA - Nord America 15.373
EU - Europa 11.654
SA - Sud America 2.090
Continente sconosciuto - Info sul continente non disponibili 482
AF - Africa 377
OC - Oceania 19
Totale 46.126
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Nazione #
US - Stati Uniti d'America 14.674
SG - Singapore 7.346
RU - Federazione Russa 5.044
VN - Vietnam 3.008
CN - Cina 2.879
IT - Italia 2.585
BR - Brasile 1.681
HK - Hong Kong 1.298
DE - Germania 836
FI - Finlandia 611
FR - Francia 600
NL - Olanda 456
CA - Canada 421
GB - Regno Unito 329
UA - Ucraina 328
BD - Bangladesh 301
IE - Irlanda 280
JP - Giappone 263
SE - Svezia 233
IN - India 198
AR - Argentina 151
MX - Messico 148
CI - Costa d'Avorio 108
IQ - Iraq 97
TH - Thailandia 85
KR - Corea 81
PH - Filippine 80
EC - Ecuador 79
ZA - Sudafrica 78
TR - Turchia 77
PL - Polonia 71
ES - Italia 69
ID - Indonesia 66
TW - Taiwan 45
PK - Pakistan 43
AT - Austria 33
VE - Venezuela 33
CO - Colombia 32
PY - Paraguay 32
CL - Cile 31
JO - Giordania 31
MA - Marocco 28
UZ - Uzbekistan 27
PE - Perù 25
BE - Belgio 23
JM - Giamaica 23
KE - Kenya 23
NP - Nepal 21
SA - Arabia Saudita 21
CR - Costa Rica 20
DZ - Algeria 20
EG - Egitto 20
TN - Tunisia 19
AE - Emirati Arabi Uniti 18
MY - Malesia 18
LT - Lituania 17
IL - Israele 16
AU - Australia 15
IR - Iran 15
GT - Guatemala 14
BG - Bulgaria 13
CH - Svizzera 13
CZ - Repubblica Ceca 13
NG - Nigeria 12
OM - Oman 12
LB - Libano 11
AZ - Azerbaigian 10
BO - Bolivia 10
NI - Nicaragua 10
TT - Trinidad e Tobago 10
UY - Uruguay 10
GR - Grecia 9
HN - Honduras 9
DO - Repubblica Dominicana 8
KZ - Kazakistan 8
NO - Norvegia 8
RO - Romania 8
AL - Albania 7
BY - Bielorussia 7
HR - Croazia 7
HU - Ungheria 7
SV - El Salvador 7
ET - Etiopia 6
IS - Islanda 6
KG - Kirghizistan 6
LV - Lettonia 6
RS - Serbia 6
SY - Repubblica araba siriana 6
BA - Bosnia-Erzegovina 5
CM - Camerun 5
DK - Danimarca 5
EU - Europa 5
GA - Gabon 5
PS - Palestinian Territory 5
SN - Senegal 5
TJ - Tagikistan 5
BB - Barbados 4
CG - Congo 4
KH - Cambogia 4
LK - Sri Lanka 4
Totale 45.525
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Città #
Singapore 3.344
San Jose 2.459
Ashburn 1.605
Hong Kong 1.236
Moscow 1.227
Chandler 1.081
Ho Chi Minh City 863
Beijing 797
Hanoi 726
Millbury 520
Naples 502
Santa Clara 484
The Dalles 472
Jacksonville 435
Princeton 418
Los Angeles 414
Lauterbourg 412
Amsterdam 392
Council Bluffs 352
Nanjing 333
Boston 224
Tokyo 223
Buffalo 216
Napoli 209
New York 204
Hefei 196
Ottawa 186
Wilmington 182
Munich 161
Redondo Beach 147
São Paulo 143
Dallas 129
Rome 121
Da Nang 114
Haiphong 112
Milan 111
Nanchang 110
Turku 102
Seattle 101
Norwalk 86
Helsinki 82
Mexico City 76
Montreal 76
Orem 76
Phoenix 67
Chicago 65
Frankfurt am Main 65
Houston 65
Brooklyn 63
Des Moines 62
Shenyang 62
Warsaw 62
Denver 61
Toronto 58
Changsha 56
Dearborn 56
London 54
Woodbridge 53
Atlanta 52
Tianjin 52
Falls Church 50
Lawrence 50
Hebei 49
Rio de Janeiro 48
Falkenstein 47
Johannesburg 45
Belo Horizonte 42
Kronberg 42
Kunming 41
Poplar 41
Hải Dương 40
Washington 40
Formia 39
San Francisco 37
Dong Ket 36
Nuremberg 36
Stockholm 36
Biên Hòa 35
Chennai 35
Seoul 35
Can Tho 34
Baghdad 33
Curitiba 33
Jiaxing 33
Manchester 32
Barano d'Ischia 29
Brasília 29
Palermo 29
Amman 28
Bangkok 28
Guangzhou 28
Hangzhou 28
Ann Arbor 27
Ankara 26
Thái Bình 26
Florence 25
Shanghai 25
Boardman 23
Tashkent 23
Augusta 22
Totale 23.797
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Nome #
7-nitro-5-fenil-1(pirrolidin-1-ilmetil)-1H-benzo[e][1,4] diazepin-2(3H)-one ed altri composti derivati delle benzodiazepine 394
Trattato di Farmacologia 325
5th international conference on Na+/Ca2+ exchange 304
RUOLO DELLO SCAMBIATORE SODIO/CALCIO E DELLE SUE ISOFORME IN UN MODELLO ANIMALE DI ISCHEMIA CEREBRALE FOCALE 300
Profarmaci dell’arginina con elevata attività terapeutica 287
A new nano-encapsulated TSPO ligand reduces neuroinflammation and improves cognitive functions in Alzheimer's disease model 227
Anti-miRNA103/107 encapsulated in transferrin-conjugated lipid nanoparticles crosses blood-brain barrier and reduces brain ischemic damage 201
Stroke by inducing HDAC9-dependent deacetylation of HIF-1 and Sp1, promotes TfR1 transcription and GPX4 reduction, thus determining ferroptotic neuronal death 199
Pharmacological characterization of the newly synthesized 5-amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide hydrochloride (BED) as a potent NCX3 inhibitor that worsens anoxic injury in cortical neurons, organotypic hippocampal cultures, and ischemic brain 198
Proteolysis of AKAP121 regulates mitochondrial activity during cellular hypoxia and brain ischaemia. 187
NCX1 Exchanger Cooperates with Calretinin to Confer Preconditioning-Induced Tolerance Against Cerebral Ischemia in the Striatum. 186
A novel hyperekplexia-causing mutation in the pre-trasmembrane segm 1 of the human glycine receptor alpha 1 subunit reduces membrane expression and impairs gating by agonists 186
Sp3/REST/HDAC1/HDAC2 complex represses and Sp1/HIF-1/p300 complex activates ncx1 gene transcription, in brain ischemia and in ischemic brain preconditioning, by Epigenetic mechanism 184
Effetto dell'ipossia e ipossia/riossigenazione sull'attività delle Iron Regulatory Proteins e sulla biosintesi di ferritina in colture neuronali e gliali 183
Na+/Ca2+ exchanger 1 on nuclear envelope controls PTEN/Akt pathway via nucleoplasmic Ca2+ regulation during neuronal differentiation 180
Dopamine Receptor Expression and Function in Clinically Norfunctioning Pituitari Tumors: Comparison with the Effectiveness of Cabergoline Treatment 177
ncx1, ncx2, and ncx3 gene product expression and function in neuronal anoxia and brain ischemia. 176
Preconditioning, induced by sub-toxic dose of the neurotoxin L-BMAA, delays ALS progression in mice and prevents Na+/Ca2+exchanger 3 downregulation 174
New insights in mitochondrial calcium handling by sodium/calcium exchanger 173
The functional coupling between endoplasmic reticulum and lysosomes for intracellular Ca2+ handling is disrupted in brain ischemia 173
NCX1 is a new rest target gene: role in cerebral ischemia 170
A critical role for the potassium-dependent sodium-calcium exchanger NCKX2 in protection against focal ischemic brain damage. 168
Divergent modulation of iron regulatory proteins and ferritin biosynthesis during hypoxia/reoxygenation affect neuronal death and glial cells survival 167
Involvement of PI3'-K, mitogen-activated protein kinase and protein kinase B in the up-regulation of the expression of nNOSalpha and nNOSbeta splicing variants induced by PRL-receptor activation in GH3 cells 167
BHK cells transfected with NCX3 are more resistant to hypoxia followed by reoxygenation than those transfected with NCX1 and NCX2: Possible relationship with mitochondrial membrane potential 166
A1-42 fragment induces an up-regulation of NCX3 activity that prevents caspase-12 activation. 166
Chronic exposure to l-BMAA cyanotoxin induces cytoplasmic TDP-43 accumulation and glial activation, reproducing an amyotrophic lateral sclerosis-like phenotype in mice 164
Genetically modified mice as a strategy to unravel the role played by the na(+)/ca (2+) exchanger in brain ischemia and in spatial learning and memory deficits 163
The expression and activity of KV3.4 channel subunits are precociously upregulated in astrocytes exposed to Aβ oligomers and in astrocytes of Alzheimer's disease Tg2576 mice 163
Sumoylation of sodium/calcium exchanger in brain ischemia and ischemic preconditioning 163
Decreased subunit stability as a novel mechanism for potassium current impairment by a KCNQ2 C terminus mutation causing benign familial neonatal convulsions 162
miR135a administration ameliorates brain ischemic damage by preventing TRPM7 activation during brain ischemia 161
Acute and long-term NCX activation reduces brain injury and restores behavioral functions in mice subjected to neonatal brain ischemia 161
miR-206 Reduces the Severity of Motor Neuron Degeneration in the Facial Nuclei of the Brainstem in a Mouse Model of SMA 161
Amyloid β-Induced Upregulation of Nav1.6 Underlies Neuronal Hyperactivity in Tg2576 Alzheimer's Disease Mouse Model 159
Emerging Role of DREAM in Healthy Brain and Neurological Diseases 158
CuZn Superoxide dismutase increases intracellular calcium levels via phospholipase C-protein Kinase C pathway in SK-N-BE cells 158
Endoplasmic reticulum refilling and mitochondrial calcium extrusion promoted in neurons by NCX1 and NCX3 in ischemic preconditioning are determinant for neuroprotection 158
Involvement of the Na+/Ca2+ exchanger isoform 1 (NCX1) in neuronal growth factor (NGF)-induced neuronal differentiation through Ca2+-dependent Akt phosphorylation 158
Hypoxia/Reoxygenation differently modulates Iron Regulatory Proteins activity and ferritin biosynthesis in rat glial cells and neurons 155
Differential expression of the Na+-Ca2+ exchanger transcripts and proteins in rat brain regions. 155
Involvement of KCNQ2 subunits in [3H]dopamine release triggered by depolarization and pre-synaptic muscarinic receptor activation from rat striatal synaptosomes. 154
Hypoxia/reoxygenation differently modulates the activity of iron regulatory proteins and ferritin biosynthesis in rat glial cells and neurons 153
Ionic Homeostasis Maintenance in ALS: Focus on New Therapeutic Targets 153
Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system 153
Anti-miR-223-5p Ameliorates Ischemic Damage and Improves Neurological Function by Preventing NCKX2 Downregulation after Ischemia in Rats 153
TSH/cAMP up-regulate sarco/endoplasmic reticulum Ca2+-ATPases expression and activity in PC Cl3 thyroid cells 152
Lysosomal dysfunction disrupts presynaptic maintenance and restoration of presynaptic function prevents neurodegeneration in lysosomal storage diseases 152
ApoSOD1 lacking dismutase activity neuroprotects motor neurons exposed to beta-methylamino-L-alanine through the Ca(2+)/Akt/ERK1/2 prosurvival pathway 152
Synthesis and Pharmacological Evaluation of a Novel Peptide Based on Anemonia sulcata BDS-I Toxin as a New KV3.4 Inhibitor Exerting a Neuroprotective Effect Against Amyloid-β Peptide 152
Arginine prodrugs with high therapeutic activity 150
Expression pattern of the ether-a-gogo-related (ERG) k+ channel-encoding genes ERG1, ERG2, and ERG3 in the adult rat central nervous system 149
Neuroprotective Effect of VEGF-Mimetic Peptide QK in Experimental Brain Ischemia Induced in Rat by Middle Cerebral Artery Occlusion 149
Development validation of LC-MS/MS method and determination of pharmacokinetic parameters of the stroke neuroprotectant neurounina-1 in beagle dog plasma after intravenous administration 149
The Na+/Ca2+ exchanger isoform 3 (NCX3) but not isoform 2 (NCX2) and 1 (NCX1) singly transfected in BHK cells plays a protective role in a model of in vitro hypoxia 148
The modulation of intracellular Ca2+ homeostasis is involved in SOD1 and ApoSOD1-induced neuroprotection of motor neurons exposed to beta-methylamino-L-alanine 148
A New Cell-penetrating Peptide That Blocks the Autoinhibitory XIP Domain of NCX1 and Enhances Antiporter Activity 147
Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage. 146
Genetic ablation of homeodomain-interacting protein kinase 2 selectively induces apoptosis of cerebellar Purkinje cells during adulthood and generates an ataxic-like phenotype 146
NCX1 Is a Novel Target Gene for Hypoxia-Inducible Factor-1 in Ischemic Brain Preconditioning 145
HDAC4 and HDAC5 form a complex with DREAM that epigenetically down-regulates NCX3 gene and its pharmacological inhibition reduces neuronal stroke damage 145
Ncx3-induced mitochondrial dysfunction in midbrain leads to neuroinflammation in striatum of A53t-α-synuclein transgenic old mice 145
Macroprolactinoma shrinkage during cabergoline treatment is greater in naive patients than in patients pretreated with other dopamine agonists: a prospective study in 110 patients 144
Zinc inhibits calcium-mediated and nitric oxide-mediated ion secretion in human enterocytes 144
Genetic Up-Regulation or Pharmacological Activation of the Na+/Ca2+ Exchanger 1 (NCX1) Enhances Hippocampal-Dependent Contextual and Spatial Learning and Memory 144
ASIC1a contributes to neuroprotection elicited by ischemic preconditioning and postconditioning 143
Genetically modified mice to unravel physiological and pathophysiological roles played by NCX isoforms 143
Control of PKA stability and signalling by the RING ligase praja2 142
Differential expression of the Na+-Ca2+ exchanger transcripts and proteins in rat brain regions 140
Divergent modulation of iron regulatory proteins and ferritin biosynthesis by hypoxia/reoxygenation in neurones and glial cells 140
Sumoylation of LYS590 of NCX3 f-Loop by SUMO1 Participates in Brain Neuroprotection Induced By Ischemic Preconditioning 140
Neuronal death and astrocytes survival during hypoxia/reoxygenation are affected by opposite modulation of Iron Regulatory Proteins and ferritin biosynthesis 139
Evidence for a protective role played by Na+-Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats 139
Tumor necrosis factor-alpha increases after corticotropin-releasing hormone administration in Cushing's disease. In vivo and in vitro studies. 139
Neuronal NCX1 overexpression induces stroke resistance while knockout induces vulnerability via Akt 139
GATA3 (GATA-binding protein 3)/KMT2A (lysine-methyltransferase-2A) complex by increasing H3K4-3me (trimethylated lysine-4 of histone-3) upregulates NCX3 (Na+-Ca2+exchanger 3) transcription and contributes to ischemic preconditioning neuroprotection 138
Pharmacological inhibition of carbonic anhydrases with a positively charged pyridinium sulfonamide phenocopies the neuroprotective effects of Car9 genetic ablation in a murine setting of oxygen/glucose deprivation followed by re-oxygenation and is associated with improved neuronal function in ischemic rats 137
Involvement of KV3.4 Channel in Parkinson's Disease: A Key Player in the Control of Midbrain and Striatum Differential Vulnerability during Disease Progression? 137
Galactosyl derivatives of L-arginine and D-arginine: synthesis, stability, cell permeation, and nitric oxide production in pituitary GH3 cells 136
Pure uptake blockers of dopamine can reduce prolactin secretion: studies with diclofensine 136
7-nitro-5-phenyl-1-(pyrrolidin-1-ylmethyl)-1H-benzo[E][1,4]diazepin-2(3H)-one and other benzodiazepine derivatives 136
Ncx3 gene ablation impairs oligodendrocyte precursor response and increases susceptibility to experimental autoimmune encephalomyelitis 136
D-Aspartate treatment attenuates myelin damage and stimulates myelin repair 136
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 135
Molecular pharmacology of the amiloride analog 3-amino-6-chloro-5-[(4-chloro-benzyl)amino]-n-[[(2,4-dimethylbenzyl)-amino]iminomethyl]-pyrazinecarboxamide (CB-DMB) as a pan inhibitor of the Na+-Ca2+ exchanger isoforms NCX1, NCX2, and NCX3 in stably transfected cells 135
ORAI1/STIM1 Interaction Intervenes in Stroke and in Neuroprotection Induced by Ischemic Preconditioning Through Store-Operated Calcium Entry 135
Differential Vulnerability of Cortical and Cerebellar Neurons in Primary Culture to Oxygen Glucose Deprivation followed by Reoxygenation. 134
M Channels Containing KCNQ2 Subunits Modulate Norepinephrine, Aspartate, and GABA Release from Hippocampal Nerve Terminals 134
A novel KCNQ2 K+ channel mutation in benign neonatal convulsions and centrotemporal spikes 134
Dopamine receptor expression and function in clinically nonfunctioning pituitary tumors: comparison with the effectiveness of cabergoline treatment 134
Two sodium/calcium exchanger gene products, NCX1 and NCX3, play a major role in the development of permanent focal cerebral ischemia. 134
Transcriptional Regulation of ncx1 Gene in the Brain 134
The 2-oxopyrrolidinacetamide piracetam reduces infarct brain volume induced by permanent middle cerebral artery occlusion in male rats. 133
Ruolo HIF-1 e NFkB nella regolazione trascrizionale del gene ncx-1 durante l'ischemia cerebrale 133
Regulation of the human ether-a-gogo related gene (HERG) K+ channels by reactive oxygen species 133
Modulation of ZnT-1 by Let7a unveils a therapeutic potential in amyotrophic lateral sclerosis 132
Retigabine and flupirtine exert neuroprotective actions in organotypic hippocampal cultures. 132
Expression pattern of the ether-a-gogo-related (ERG) K+ channel-encoding genes ERG1, ERG2, and ERG3 in the adult rat central nervous system. 132
NCX1 and NCX3: Two new effectors of delayed preconditioning in brain ischemia 132
In vivo imaging of CNS microglial activation/macrophage infiltration with combined [18F]DPA-714-PET and SPIO-MRI in a mouse model of relapsing remitting experimental autoimmune encephalomyelitis 132
Totale 16.154
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Categoria #
all - tutte 153.010
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 153.010
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.428 0 5 21 28 19 99 38 104 310 161 561 1.082
2022/20232.711 494 261 69 190 323 269 24 189 337 382 125 48
2023/20242.449 69 246 264 152 103 204 33 739 20 53 380 186
2024/202511.267 623 732 53 149 231 523 1.172 688 1.064 1.067 3.948 1.017
2025/202621.527 2.460 1.222 2.169 1.949 3.690 801 2.681 1.342 2.832 1.315 533 533
2026/20271.172 478 694 0 0 0 0 0 0 0 0 0 0
Totale 46.126