IRIS
ANNUNZIATO, LUCIO
 Distribuzione geografica
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Continente #
AS - Asia 15.920
NA - Nord America 14.173
EU - Europa 11.456
SA - Sud America 2.039
AF - Africa 371
OC - Oceania 19
Continente sconosciuto - Info sul continente non disponibili 9
Totale 43.987
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Nazione #
US - Stati Uniti d'America 13.578
SG - Singapore 7.340
RU - Federazione Russa 5.044
VN - Vietnam 2.998
CN - Cina 2.842
IT - Italia 2.417
BR - Brasile 1.657
HK - Hong Kong 1.290
DE - Germania 835
FI - Finlandia 611
FR - Francia 593
NL - Olanda 453
CA - Canada 363
UA - Ucraina 327
GB - Regno Unito 320
IE - Irlanda 280
JP - Giappone 262
SE - Svezia 233
IN - India 198
BD - Bangladesh 177
AR - Argentina 144
MX - Messico 144
CI - Costa d'Avorio 107
IQ - Iraq 97
TH - Thailandia 82
KR - Corea 81
ZA - Sudafrica 78
TR - Turchia 76
PH - Filippine 75
EC - Ecuador 73
PL - Polonia 70
ES - Italia 67
ID - Indonesia 61
TW - Taiwan 45
PK - Pakistan 43
AT - Austria 33
PY - Paraguay 32
JO - Giordania 30
VE - Venezuela 30
MA - Marocco 28
CL - Cile 27
UZ - Uzbekistan 27
CO - Colombia 25
PE - Perù 25
KE - Kenya 23
BE - Belgio 22
DZ - Algeria 20
EG - Egitto 20
SA - Arabia Saudita 20
NP - Nepal 19
TN - Tunisia 19
LT - Lituania 17
AE - Emirati Arabi Uniti 16
IL - Israele 16
AU - Australia 15
CR - Costa Rica 15
IR - Iran 15
MY - Malesia 14
BG - Bulgaria 13
CH - Svizzera 12
CZ - Repubblica Ceca 12
NG - Nigeria 12
OM - Oman 12
GT - Guatemala 11
JM - Giamaica 11
LB - Libano 11
AZ - Azerbaigian 10
BO - Bolivia 10
UY - Uruguay 10
GR - Grecia 9
HN - Honduras 8
KZ - Kazakistan 8
NO - Norvegia 8
AL - Albania 7
BY - Bielorussia 7
DO - Repubblica Dominicana 7
HR - Croazia 7
HU - Ungheria 7
NI - Nicaragua 7
RO - Romania 7
ET - Etiopia 6
IS - Islanda 6
KG - Kirghizistan 6
LV - Lettonia 6
RS - Serbia 6
SY - Repubblica araba siriana 6
TT - Trinidad e Tobago 6
BA - Bosnia-Erzegovina 5
CM - Camerun 5
EU - Europa 5
GA - Gabon 5
PS - Palestinian Territory 5
SN - Senegal 5
SV - El Salvador 5
TJ - Tagikistan 5
DK - Danimarca 4
KH - Cambogia 4
LK - Sri Lanka 4
PT - Portogallo 4
AF - Afghanistan, Repubblica islamica di 3
Totale 43.876
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Città #
Singapore 3.341
San Jose 2.314
Ashburn 1.504
Hong Kong 1.231
Moscow 1.227
Chandler 1.081
Ho Chi Minh City 860
Beijing 795
Hanoi 723
Millbury 520
Naples 477
The Dalles 472
Santa Clara 444
Jacksonville 432
Princeton 417
Lauterbourg 412
Amsterdam 392
Los Angeles 392
Nanjing 333
Boston 223
Tokyo 223
Buffalo 210
Napoli 209
Hefei 196
New York 190
Ottawa 184
Wilmington 182
Munich 161
Redondo Beach 147
São Paulo 136
Da Nang 114
Haiphong 111
Nanchang 110
Dallas 108
Rome 108
Turku 102
Seattle 100
Milan 86
Norwalk 85
Helsinki 82
Orem 75
Mexico City 73
Montreal 71
Frankfurt am Main 65
Des Moines 62
Shenyang 62
Houston 61
Warsaw 61
Brooklyn 58
Changsha 56
Dearborn 56
Denver 54
London 53
Chicago 52
Tianjin 52
Woodbridge 52
Falls Church 50
Lawrence 50
Atlanta 49
Hebei 49
Toronto 49
Falkenstein 47
Rio de Janeiro 47
Phoenix 46
Johannesburg 45
Belo Horizonte 42
Kronberg 42
Kunming 41
Poplar 41
Hải Dương 40
Council Bluffs 39
Formia 39
Washington 38
Dong Ket 36
Nuremberg 36
Stockholm 36
Biên Hòa 35
Chennai 35
San Francisco 35
Seoul 35
Can Tho 34
Baghdad 33
Jiaxing 33
Curitiba 32
Manchester 31
Barano d'Ischia 29
Brasília 29
Palermo 29
Hangzhou 28
Amman 27
Ann Arbor 27
Guangzhou 27
Ankara 26
Bangkok 26
Thái Bình 26
Boardman 23
Tashkent 23
Bologna 22
Caserta 22
Portici 22
Totale 22.948
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Nome #
7-nitro-5-fenil-1(pirrolidin-1-ilmetil)-1H-benzo[e][1,4] diazepin-2(3H)-one ed altri composti derivati delle benzodiazepine 391
5th international conference on Na+/Ca2+ exchange 303
RUOLO DELLO SCAMBIATORE SODIO/CALCIO E DELLE SUE ISOFORME IN UN MODELLO ANIMALE DI ISCHEMIA CEREBRALE FOCALE 297
Trattato di Farmacologia 296
Profarmaci dell’arginina con elevata attività terapeutica 277
Stroke by inducing HDAC9-dependent deacetylation of HIF-1 and Sp1, promotes TfR1 transcription and GPX4 reduction, thus determining ferroptotic neuronal death 194
Pharmacological characterization of the newly synthesized 5-amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide hydrochloride (BED) as a potent NCX3 inhibitor that worsens anoxic injury in cortical neurons, organotypic hippocampal cultures, and ischemic brain 193
Anti-miRNA103/107 encapsulated in transferrin-conjugated lipid nanoparticles crosses blood-brain barrier and reduces brain ischemic damage 192
NCX1 Exchanger Cooperates with Calretinin to Confer Preconditioning-Induced Tolerance Against Cerebral Ischemia in the Striatum. 183
A novel hyperekplexia-causing mutation in the pre-trasmembrane segm 1 of the human glycine receptor alpha 1 subunit reduces membrane expression and impairs gating by agonists 183
Effetto dell'ipossia e ipossia/riossigenazione sull'attività delle Iron Regulatory Proteins e sulla biosintesi di ferritina in colture neuronali e gliali 180
Sp3/REST/HDAC1/HDAC2 complex represses and Sp1/HIF-1/p300 complex activates ncx1 gene transcription, in brain ischemia and in ischemic brain preconditioning, by Epigenetic mechanism 180
Na+/Ca2+ exchanger 1 on nuclear envelope controls PTEN/Akt pathway via nucleoplasmic Ca2+ regulation during neuronal differentiation 177
Proteolysis of AKAP121 regulates mitochondrial activity during cellular hypoxia and brain ischaemia. 175
ncx1, ncx2, and ncx3 gene product expression and function in neuronal anoxia and brain ischemia. 172
The functional coupling between endoplasmic reticulum and lysosomes for intracellular Ca2+ handling is disrupted in brain ischemia 170
Divergent modulation of iron regulatory proteins and ferritin biosynthesis during hypoxia/reoxygenation affect neuronal death and glial cells survival 166
NCX1 is a new rest target gene: role in cerebral ischemia 166
Preconditioning, induced by sub-toxic dose of the neurotoxin L-BMAA, delays ALS progression in mice and prevents Na+/Ca2+exchanger 3 downregulation 166
A critical role for the potassium-dependent sodium-calcium exchanger NCKX2 in protection against focal ischemic brain damage. 165
BHK cells transfected with NCX3 are more resistant to hypoxia followed by reoxygenation than those transfected with NCX1 and NCX2: Possible relationship with mitochondrial membrane potential 164
Involvement of PI3'-K, mitogen-activated protein kinase and protein kinase B in the up-regulation of the expression of nNOSalpha and nNOSbeta splicing variants induced by PRL-receptor activation in GH3 cells 163
A1-42 fragment induces an up-regulation of NCX3 activity that prevents caspase-12 activation. 163
The expression and activity of KV3.4 channel subunits are precociously upregulated in astrocytes exposed to Aβ oligomers and in astrocytes of Alzheimer's disease Tg2576 mice 159
Dopamine Receptor Expression and Function in Clinically Norfunctioning Pituitari Tumors: Comparison with the Effectiveness of Cabergoline Treatment 158
Genetically modified mice as a strategy to unravel the role played by the na(+)/ca (2+) exchanger in brain ischemia and in spatial learning and memory deficits 158
miR135a administration ameliorates brain ischemic damage by preventing TRPM7 activation during brain ischemia 157
Acute and long-term NCX activation reduces brain injury and restores behavioral functions in mice subjected to neonatal brain ischemia 157
Decreased subunit stability as a novel mechanism for potassium current impairment by a KCNQ2 C terminus mutation causing benign familial neonatal convulsions 156
miR-206 Reduces the Severity of Motor Neuron Degeneration in the Facial Nuclei of the Brainstem in a Mouse Model of SMA 156
CuZn Superoxide dismutase increases intracellular calcium levels via phospholipase C-protein Kinase C pathway in SK-N-BE cells 154
Involvement of the Na+/Ca2+ exchanger isoform 1 (NCX1) in neuronal growth factor (NGF)-induced neuronal differentiation through Ca2+-dependent Akt phosphorylation 154
Chronic exposure to l-BMAA cyanotoxin induces cytoplasmic TDP-43 accumulation and glial activation, reproducing an amyotrophic lateral sclerosis-like phenotype in mice 153
Differential expression of the Na+-Ca2+ exchanger transcripts and proteins in rat brain regions. 153
Hypoxia/Reoxygenation differently modulates Iron Regulatory Proteins activity and ferritin biosynthesis in rat glial cells and neurons 152
Amyloid β-Induced Upregulation of Nav1.6 Underlies Neuronal Hyperactivity in Tg2576 Alzheimer's Disease Mouse Model 152
A new nano-encapsulated TSPO ligand reduces neuroinflammation and improves cognitive functions in Alzheimer's disease model 151
Involvement of KCNQ2 subunits in [3H]dopamine release triggered by depolarization and pre-synaptic muscarinic receptor activation from rat striatal synaptosomes. 151
Hypoxia/reoxygenation differently modulates the activity of iron regulatory proteins and ferritin biosynthesis in rat glial cells and neurons 151
ApoSOD1 lacking dismutase activity neuroprotects motor neurons exposed to beta-methylamino-L-alanine through the Ca(2+)/Akt/ERK1/2 prosurvival pathway 151
Endoplasmic reticulum refilling and mitochondrial calcium extrusion promoted in neurons by NCX1 and NCX3 in ischemic preconditioning are determinant for neuroprotection 150
Ionic Homeostasis Maintenance in ALS: Focus on New Therapeutic Targets 149
Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system 149
TSH/cAMP up-regulate sarco/endoplasmic reticulum Ca2+-ATPases expression and activity in PC Cl3 thyroid cells 147
Lysosomal dysfunction disrupts presynaptic maintenance and restoration of presynaptic function prevents neurodegeneration in lysosomal storage diseases 147
Synthesis and Pharmacological Evaluation of a Novel Peptide Based on Anemonia sulcata BDS-I Toxin as a New KV3.4 Inhibitor Exerting a Neuroprotective Effect Against Amyloid-β Peptide 146
Anti-miR-223-5p Ameliorates Ischemic Damage and Improves Neurological Function by Preventing NCKX2 Downregulation after Ischemia in Rats 146
Genetic ablation of homeodomain-interacting protein kinase 2 selectively induces apoptosis of cerebellar Purkinje cells during adulthood and generates an ataxic-like phenotype 145
Development validation of LC-MS/MS method and determination of pharmacokinetic parameters of the stroke neuroprotectant neurounina-1 in beagle dog plasma after intravenous administration 145
Arginine prodrugs with high therapeutic activity 145
The Na+/Ca2+ exchanger isoform 3 (NCX3) but not isoform 2 (NCX2) and 1 (NCX1) singly transfected in BHK cells plays a protective role in a model of in vitro hypoxia 143
NCX1 Is a Novel Target Gene for Hypoxia-Inducible Factor-1 in Ischemic Brain Preconditioning 143
A New Cell-penetrating Peptide That Blocks the Autoinhibitory XIP Domain of NCX1 and Enhances Antiporter Activity 143
Expression pattern of the ether-a-gogo-related (ERG) k+ channel-encoding genes ERG1, ERG2, and ERG3 in the adult rat central nervous system 142
Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage. 142
The modulation of intracellular Ca2+ homeostasis is involved in SOD1 and ApoSOD1-induced neuroprotection of motor neurons exposed to beta-methylamino-L-alanine 142
ASIC1a contributes to neuroprotection elicited by ischemic preconditioning and postconditioning 141
Neuroprotective Effect of VEGF-Mimetic Peptide QK in Experimental Brain Ischemia Induced in Rat by Middle Cerebral Artery Occlusion 141
Zinc inhibits calcium-mediated and nitric oxide-mediated ion secretion in human enterocytes 140
HDAC4 and HDAC5 form a complex with DREAM that epigenetically down-regulates NCX3 gene and its pharmacological inhibition reduces neuronal stroke damage 140
Ncx3-induced mitochondrial dysfunction in midbrain leads to neuroinflammation in striatum of A53t-α-synuclein transgenic old mice 140
Emerging Role of DREAM in Healthy Brain and Neurological Diseases 139
New insights in mitochondrial calcium handling by sodium/calcium exchanger 139
Genetic Up-Regulation or Pharmacological Activation of the Na+/Ca2+ Exchanger 1 (NCX1) Enhances Hippocampal-Dependent Contextual and Spatial Learning and Memory 139
Macroprolactinoma shrinkage during cabergoline treatment is greater in naive patients than in patients pretreated with other dopamine agonists: a prospective study in 110 patients 138
Control of PKA stability and signalling by the RING ligase praja2 138
Genetically modified mice to unravel physiological and pathophysiological roles played by NCX isoforms 137
Neuronal death and astrocytes survival during hypoxia/reoxygenation are affected by opposite modulation of Iron Regulatory Proteins and ferritin biosynthesis 136
Divergent modulation of iron regulatory proteins and ferritin biosynthesis by hypoxia/reoxygenation in neurones and glial cells 136
Evidence for a protective role played by Na+-Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats 135
Tumor necrosis factor-alpha increases after corticotropin-releasing hormone administration in Cushing's disease. In vivo and in vitro studies. 135
Sumoylation of LYS590 of NCX3 f-Loop by SUMO1 Participates in Brain Neuroprotection Induced By Ischemic Preconditioning 135
Sumoylation of sodium/calcium exchanger in brain ischemia and ischemic preconditioning 135
GATA3 (GATA-binding protein 3)/KMT2A (lysine-methyltransferase-2A) complex by increasing H3K4-3me (trimethylated lysine-4 of histone-3) upregulates NCX3 (Na+-Ca2+exchanger 3) transcription and contributes to ischemic preconditioning neuroprotection 135
Pure uptake blockers of dopamine can reduce prolactin secretion: studies with diclofensine 134
Neuronal NCX1 overexpression induces stroke resistance while knockout induces vulnerability via Akt 134
Ncx3 gene ablation impairs oligodendrocyte precursor response and increases susceptibility to experimental autoimmune encephalomyelitis 134
Differential expression of the Na+-Ca2+ exchanger transcripts and proteins in rat brain regions 133
Molecular pharmacology of the amiloride analog 3-amino-6-chloro-5-[(4-chloro-benzyl)amino]-n-[[(2,4-dimethylbenzyl)-amino]iminomethyl]-pyrazinecarboxamide (CB-DMB) as a pan inhibitor of the Na+-Ca2+ exchanger isoforms NCX1, NCX2, and NCX3 in stably transfected cells 133
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 132
Galactosyl derivatives of L-arginine and D-arginine: synthesis, stability, cell permeation, and nitric oxide production in pituitary GH3 cells 132
M Channels Containing KCNQ2 Subunits Modulate Norepinephrine, Aspartate, and GABA Release from Hippocampal Nerve Terminals 132
A novel KCNQ2 K+ channel mutation in benign neonatal convulsions and centrotemporal spikes 132
Involvement of KV3.4 Channel in Parkinson's Disease: A Key Player in the Control of Midbrain and Striatum Differential Vulnerability during Disease Progression? 131
Two sodium/calcium exchanger gene products, NCX1 and NCX3, play a major role in the development of permanent focal cerebral ischemia. 131
Transcriptional Regulation of ncx1 Gene in the Brain 131
7-nitro-5-phenyl-1-(pyrrolidin-1-ylmethyl)-1H-benzo[E][1,4]diazepin-2(3H)-one and other benzodiazepine derivatives 131
D-Aspartate treatment attenuates myelin damage and stimulates myelin repair 131
ORAI1/STIM1 Interaction Intervenes in Stroke and in Neuroprotection Induced by Ischemic Preconditioning Through Store-Operated Calcium Entry 131
Dopamine receptor expression and function in clinically nonfunctioning pituitary tumors: comparison with the effectiveness of cabergoline treatment 130
Regulation of the human ether-a-gogo related gene (HERG) K+ channels by reactive oxygen species 130
Retigabine and flupirtine exert neuroprotective actions in organotypic hippocampal cultures. 129
Differential Vulnerability of Cortical and Cerebellar Neurons in Primary Culture to Oxygen Glucose Deprivation followed by Reoxygenation. 129
Antithrombin reduces ischemic volume, ameliorates neurologic deficits, and prolongs animal survival in both transient and permanent focal ischemia 129
Anoxia-induced NF-kappaB-dependent upregulation of NCX1 contributes to Ca2+ refilling into endoplasmic reticulum in cortical neurons 129
NCX1 and NCX3: Two new effectors of delayed preconditioning in brain ischemia 129
Expression pattern of the ether-a-gogo-related (ERG) K+ channel-encoding genes ERG1, ERG2, and ERG3 in the adult rat central nervous system. 128
The 2-oxopyrrolidinacetamide piracetam reduces infarct brain volume induced by permanent middle cerebral artery occlusion in male rats. 128
The NCX3 isoform of the Na(+)/Ca(2+) exchanger contributes to neuroprotection elicited by ischemic postconditioning 128
Neuronal NOS activation during oxygen and glucose deprivation triggers cerebellar granule cell death in the later reoxygenation phase 127
Totale 15.540
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Categoria #
all - tutte 138.717
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 138.717
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202162 0 0 0 0 0 0 0 0 0 0 0 62
2021/20222.485 57 5 21 28 19 99 38 104 310 161 561 1.082
2022/20232.711 494 261 69 190 323 269 24 189 337 382 125 48
2023/20242.449 69 246 264 152 103 204 33 739 20 53 380 186
2024/202511.267 623 732 53 149 231 523 1.172 688 1.064 1.067 3.948 1.017
2025/202621.031 2.460 1.222 2.169 1.949 3.690 801 2.681 1.342 2.832 1.315 533 37
Totale 44.458