IRIS
DI RENZO, GIANFRANCO MARIA LUIGI
 Distribuzione geografica
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Continente #
EU - Europa 5.537
NA - Nord America 4.790
AS - Asia 2.846
SA - Sud America 473
AF - Africa 110
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 1
Totale 13.762
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Nazione #
US - Stati Uniti d'America 4.606
RU - Federazione Russa 2.650
SG - Singapore 1.343
IT - Italia 884
CN - Cina 687
HK - Hong Kong 658
DE - Germania 452
BR - Brasile 426
FI - Finlandia 341
NL - Olanda 297
UA - Ucraina 295
IE - Irlanda 219
CA - Canada 160
SE - Svezia 116
GB - Regno Unito 113
FR - Francia 101
CI - Costa d'Avorio 76
VN - Vietnam 30
IN - India 29
TR - Turchia 26
MX - Messico 20
ZA - Sudafrica 17
BD - Bangladesh 16
AR - Argentina 13
BE - Belgio 13
IQ - Iraq 13
ES - Italia 11
MA - Marocco 11
PL - Polonia 10
CL - Cile 9
PE - Perù 9
EC - Ecuador 8
IR - Iran 8
JP - Giappone 8
CZ - Repubblica Ceca 6
AT - Austria 5
CH - Svizzera 5
EU - Europa 4
NO - Norvegia 4
SA - Arabia Saudita 4
UZ - Uzbekistan 4
VE - Venezuela 4
ID - Indonesia 3
IL - Israele 3
KE - Kenya 3
LT - Lituania 3
NP - Nepal 3
EG - Egitto 2
GR - Grecia 2
GT - Guatemala 2
HU - Ungheria 2
IS - Islanda 2
KG - Kirghizistan 2
OM - Oman 2
PK - Pakistan 2
RS - Serbia 2
UY - Uruguay 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AE - Emirati Arabi Uniti 1
AL - Albania 1
AU - Australia 1
BG - Bulgaria 1
BY - Bielorussia 1
CO - Colombia 1
DO - Repubblica Dominicana 1
KR - Corea 1
LK - Sri Lanka 1
MY - Malesia 1
PY - Paraguay 1
RO - Romania 1
TN - Tunisia 1
TT - Trinidad e Tobago 1
TW - Taiwan 1
Totale 13.762
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Città #
Singapore 799
Moscow 682
Chandler 674
Hong Kong 642
Ashburn 464
Millbury 307
Jacksonville 306
Amsterdam 280
Princeton 267
Santa Clara 234
Nanjing 193
Napoli 167
Ottawa 140
Naples 126
Beijing 117
Boston 107
Wilmington 97
Nanchang 69
Seattle 56
Norwalk 45
Munich 42
Turku 42
Dearborn 38
Helsinki 38
Des Moines 36
Shenyang 36
Hebei 35
Falls Church 34
Changsha 31
São Paulo 30
Tianjin 27
Dong Ket 26
Falkenstein 26
Los Angeles 26
Woodbridge 26
Formia 22
Frankfurt am Main 21
Jiaxing 21
Caserta 20
Washington 20
Milan 19
Orange 19
Kunming 18
New York 18
Kronberg 17
London 16
Rome 15
The Dalles 15
Belo Horizonte 13
Augusta 12
Brooklyn 12
Toronto 12
Dallas 11
Dublin 11
Redwood City 11
Frattaminore 10
Hangzhou 10
Ningbo 10
Palermo 10
Redmond 10
Atlanta 9
Boardman 9
Bologna 9
Brussels 9
Curitiba 9
Hefei 9
Nuremberg 9
Rio de Janeiro 9
Salerno 9
Acquafredda 8
Düsseldorf 8
Jinan 8
Lawrence 8
Leawood 8
Mexico City 8
San Francisco 8
Chennai 7
Chicago 7
Fortaleza 7
Nürnberg 7
Pavullo Nel Frignano 7
Pune 7
Turin 7
Walnut 7
Baghdad 6
Brasília 6
Catanzaro 6
Guangzhou 6
Houston 6
Olomouc 6
Rende 6
Ribeirão Preto 6
Sant'arpino 6
Warsaw 6
Bexley 5
Campinas 5
Dhaka 5
Indiana 5
Johannesburg 5
Lima 5
Totale 6.921
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Nome #
7-nitro-5-fenil-1(pirrolidin-1-ilmetil)-1H-benzo[e][1,4] diazepin-2(3H)-one ed altri composti derivati delle benzodiazepine 337
Trattato di Farmacologia 207
Triticum vulgare extract exerts an anti-inflammatory action in two in vitro models of inflammation in microglial cells 116
The antiepileptic drug levetiracetam suppresses non-convulsive seizure activity and reduces ischemic brain damage in rats subjected to permanent middle cerebral artery occlusion 108
Na+/Ca2+ exchanger 1 on nuclear envelope controls PTEN/Akt pathway via nucleoplasmic Ca2+ regulation during neuronal differentiation 104
The miR206-JunD circuit mediates the neurotoxic effect of methylmercury in cortical neurons 100
ncx1, ncx2, and ncx3 gene product expression and function in neuronal anoxia and brain ischemia. 99
Sp3/REST/HDAC1/HDAC2 complex represses and Sp1/HIF-1/p300 complex activates ncx1 gene transcription, in brain ischemia and in ischemic brain preconditioning, by Epigenetic mechanism 99
Acute and long-term NCX activation reduces brain injury and restores behavioral functions in mice subjected to neonatal brain ischemia 97
The expression and activity of KV3.4 channel subunits are precociously upregulated in astrocytes exposed to Aβ oligomers and in astrocytes of Alzheimer's disease Tg2576 mice 97
The functional coupling between endoplasmic reticulum and lysosomes for intracellular Ca2+ handling is disrupted in brain ischemia 94
L’aumento dell’RNAm e della proteina HIF-1α, una subunità della proteina Hypoxia Inducible Factor (HIF-1), indotta dall’ischemia cerebrale, attiva il gene codificante per la iNOS 92
Involvement of the Na+/Ca2+ exchanger isoform 1 (NCX1) in neuronal growth factor (NGF)-induced neuronal differentiation through Ca2+-dependent Akt phosphorylation 92
A critical role for the potassium-dependent sodium-calcium exchanger NCKX2 in protection against focal ischemic brain damage. 90
Successful treatment of post-surgical osteomyelitis caused by XDR Pseudomonas aeruginosa with ceftolozane/tazobactam monotherapy 89
Pharmacological characterization of the newly synthesized 5-amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide hydrochloride (BED) as a potent NCX3 inhibitor that worsens anoxic injury in cortical neurons, organotypic hippocampal cultures, and ischemic brain 88
ApoSOD1 lacking dismutase activity neuroprotects motor neurons exposed to beta-methylamino-L-alanine through the Ca(2+)/Akt/ERK1/2 prosurvival pathway 87
Involvement of the nitric oxide/protein kinase G pathway in polychlorinated biphenyl-induced cell death in SH-SY 5Y neuroblastoma cells 86
Neuronal NCX1 overexpression induces stroke resistance while knockout induces vulnerability via Akt 85
Preconditioning, induced by sub-toxic dose of the neurotoxin L-BMAA, delays ALS progression in mice and prevents Na+/Ca2+exchanger 3 downregulation 85
BHK cells transfected with NCX3 are more resistant to hypoxia followed by reoxygenation than those transfected with NCX1 and NCX2: Possible relationship with mitochondrial membrane potential 84
L’aumento dell’mRNA e della proteina HIF-1a, una subunità della proteina HIF-1 (Hypoxia Inducible Factor), indotta dall’ischemia cerebrale, attiva il gene codificante per la iNOS 82
Involvement of PI3'-K, mitogen-activated protein kinase and protein kinase B in the up-regulation of the expression of nNOSalpha and nNOSbeta splicing variants induced by PRL-receptor activation in GH3 cells 79
Cigarette Smoke Condensate Causes a Decrease of the Gene Expression of Cu-Zn Superoxide Dismutase, Mn Superoxide Dismutase, Glutathione Peroxidase, Catalase, and Free Radical-Induced Cell Injury in SH-SY5Y Human Neuroblastoma Cells 78
Genetically modified mice as a strategy to unravel the role played by the na(+)/ca (2+) exchanger in brain ischemia and in spatial learning and memory deficits 78
Neuroprotective Effect of VEGF-Mimetic Peptide QK in Experimental Brain Ischemia Induced in Rat by Middle Cerebral Artery Occlusion 78
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 77
ASIC1a contributes to neuroprotection elicited by ischemic preconditioning and postconditioning 77
7-nitro-5-phenyl-1-(pyrrolidin-1-ylmethyl)-1H-benzo[E][1,4]diazepin-2(3H)-one and other benzodiazepine derivatives 76
A New Cell-penetrating Peptide That Blocks the Autoinhibitory XIP Domain of NCX1 and Enhances Antiporter Activity 75
Methylmercury upregulates RE-1 silencing transcription factor (REST) in SH-SY5Y cells and mouse cerebellum 75
Genetic Up-Regulation or Pharmacological Activation of the Na+/Ca2+ Exchanger 1 (NCX1) Enhances Hippocampal-Dependent Contextual and Spatial Learning and Memory 75
. Ab1-42 fragment induces an up-regulation of NCX3 activity that prevents caspase-12 activation. 74
NCX1 is a new rest target gene: role in cerebral ischemia 74
p38/Sp1/Sp4/HDAC4/BDNF Axis Is a Novel Molecular Pathway of the Neurotoxic Effect of the Methylmercury 74
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions 73
Anoxia-induced NF-kappaB-dependent upregulation of NCX1 contributes to Ca2+ refilling into endoplasmic reticulum in cortical neurons 73
Evidence for a protective role played by Na+-Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats 72
The Na+/Ca2+ exchanger isoform 3 (NCX3) but not isoform 2 (NCX2) and 1 (NCX1) singly transfected in BHK cells plays a protective role in a model of in vitro hypoxia 72
Resveratrol via sirtuin-1 downregulates RE1-silencing transcription factor (REST) expression preventing PCB-95-induced neuronal cell death 72
MS-275 inhibits aroclor 1254-induced SH-SY5Y neuronal cell toxicity by preventing the formation of the HDAC3/REST complex on the synapsin-1 promoter 72
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 71
Alcohol increases spontaneous BOLD signal fluctuations in the visual network 71
Histone deacetylase 4 promotes ubiquitin-dependent proteasomal degradation of Sp3 in SH-SY5Y cells treated with di(2-ethylhexyl)phthalate (DEHP), determining neuronal death. 71
BHK cells transfected with NCX3 are more resistant to hypoxia followed by reoxygenation than those transfected with NCX1 and NCX2: Possible relationship with mitochondrial membrane potential. 70
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 70
Involvement of Na+-Ca2+ exchanger in intracellular Ca2+ increase and neuronal injury induced by polychlorinated biphenyls in human neuroblastoma SH-SY5Y cells 70
Molecular pharmacology of the amiloride analog 3-amino-6-chloro-5-[(4-chloro-benzyl)amino]-n-[[(2,4-dimethylbenzyl)-amino]iminomethyl]-pyrazinecarboxamide (CB-DMB) as a pan inhibitor of the Na+-Ca2+ exchanger isoforms NCX1, NCX2, and NCX3 in stably transfected cells 70
Aβ1-42 fragment induces an up-regulation of NCX3 activity that prevents caspase-12 activation 70
Transcriptional Regulation of ncx1 Gene in the Brain 70
HDAC4 and HDAC5 form a complex with DREAM that epigenetically down-regulates NCX3 gene and its pharmacological inhibition reduces neuronal stroke damage 70
Antithrombin reduces ischemic volume, ameliorates neurologic deficits, and prolongs animal survival in both transient and permanent focal ischemia 68
Up-regulation and increased activity of KV3.4 channels and their accessory subunit MinK-related peptide 2 induced by amyloid peptide are involved in apoptotic neuronal death 68
Polychlorinated biphenyls impair dibutyryl cAMP-induced astrocytic differentiation in rat C6 glial cell line 68
Alpha-melanocyte-stimulating hormone is present in the inferior petrosal sinuses in patients with Cushing's disease. 67
A pharmacological study on the possible mechanisms underlying changes in TSH secretion in aged male rats 67
Sumoylation of LYS590 of NCX3 f-Loop by SUMO1 Participates in Brain Neuroprotection Induced By Ischemic Preconditioning 67
L’ipossia modula in maniera opposta l’attività di RNA-binding di IRP1 e l’espressione della ferritina in neuroni corticali e cellule gliali 67
The neurotoxicant PCB-95 by increasing the neuronal transcriptional repressor REST down-regulates caspase-8 and increases Ripk1, Ripk3 and MLKL expression determining necroptotic neuronal death 67
Does Na(+)/Ca (2+) Exchanger, NCX, Represent a New Druggable Target in Stroke Intervention? 66
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 65
Ca2+-independent caspase-3 but not ca2+-dependent caspase-2 activation induced by oxidative stress leads to SH-SY5Y human neuroblastoma cell apoptosis 65
Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage. 65
Uso dell'Antitrombina III (ATIII) per la preparazione di formulazioni farmaceutiche per uso parenterale per il trattamento dei danni cerebrali secondari all'insulto ischemico o ad altre malattie degenerative del sistema nervoso centrale e periferico 65
NCX1 and NCX3: Two new effectors of delayed preconditioning in brain ischemia 64
Ionic homeostasis in brain conditioning 64
Zn(2+) slows down Ca(V)3.3 gating kinetics: implications for thalamocortical activity. 63
The NCX3 isoform of the Na(+)/Ca(2+) exchanger contributes to neuroprotection elicited by ischemic postconditioning 63
NO-induced neuroprotection in ischemic preconditioning stimulates mitochondrial Mn-SOD activity and expression via Ras/ERK1/2 pathway 62
NCX1 Is a Novel Target Gene for Hypoxia-Inducible Factor-1 in Ischemic Brain Preconditioning 62
A1-42 fragment induces an up-regulation of NCX3 activity that prevents caspase-12 activation. 62
Antihypertensive response to combination of olmesartan and amlodipine does not depend on method and time of drug administration. 62
MicroRNA-103-1 Selectively Downregulates Brain NCX1 and Its Inhibition by Anti-miRNA Ameliorates Stroke Damage and Neurological Deficits 62
Pharmacological blockade of ERG K+ channels and Ca2+ influx through store-operated channels exerts opposite effects on intracellular Ca2+ oscillations in pituitary GH3 cells 61
HIF-1 alpha reveals a binding- activity to the promoter of iNOS gene after permanent middle cerebral artery occlusion 61
Zn(2+) slows down Ca(V)3.3 gating kinetics: implications for thalamocortical activity 61
Lack of evidence for an inhibitory role played by tuberoinfundibular dopaminergic neurons on TSH secretion in the rat. 61
Nitric oxide stimulates NCX1 and NCX2 but inhibits NCX3 isoform by three distinct molecular determinants 61
NCX1 and NCX3 as potential factors contributing to neurodegeneration and neuroinflammation in the A53T transgenic mouse model of Parkinson's Disease 61
IMATINIB-MESYLATE BLOCKS RECOMBINANT T-TYPE CALCIUM CHANNELS EXPRESSED IN HEK-293 CELLS BY A PTK-INDEPENDENT MECHANISM 60
Preconditioning and Postconditioning Exert Stroke Neuroprotection Modulating NCX and ASIC1a Expression 60
Unique Scopolamine Withdrawal Syndrome After Standard Transdermal Use 60
Differential Vulnerability of Cortical and Cerebellar Neurons in Primary Culture to Oxygen Glucose Deprivation followed by Reoxygenation. 59
Na+/Ca2+ exchanger in Na+ efflux-Ca2+ influx mode of operation exerts a neuroprotective role in cellular models of in vitro anoxia and in vivo cerebral ischemia. 59
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions 59
Pure uptake blockers of dopamine can reduce prolactin secretion: studies with diclofensine 59
Two sodium/calcium exchanger gene products, NCX1 and NCX3, play a major role in the development of permanent focal cerebral ischemia. 59
Differential vulnerability of cortical and cerebellar neurons in primary culture to oxygen glucose deprivation followed by reoxygenation 59
ERK1/2, p38, and JNK regulate the expression and the activity of the three isoforms of the Na(+) /Ca(2+) exchanger, NCX1, NCX2, and NCX3, in neuronal PC12 cells. 59
Neurounina-1, a Novel Compound that Increases Na+/Ca2+ Exchanger Activity, Effectively Protects Against Stroke Damage 59
The modulation of intracellular Ca2+ homeostasis is involved in SOD1 and ApoSOD1-induced neuroprotection of motor neurons exposed to beta-methylamino-L-alanine 59
Differential vulnerability of cortical and cerebellar neurons in primary culture to oxygen deprivation followed by reoxygenation 58
Effects of manidipine and nitrendipine enantiomers on the plateau phase of K+-induced intracellular Ca2+ increase in GH3 cells. 58
The antiepileptic drug Leviracetam decreases the IP3-dependent [Ca2+] increase induced by ATP and BK in PC12 cells 58
Neuronal NOS activation during oxygen and glucose deprivation triggers cerebellar granule cell death in the later reoxygenation phase 58
Clinical Trials with Drugs Targeting Ionic Channels, Antiporters, and Pumps in Ischemic Stroke 58
Prolonged exposure of pituitary dopaminergic receptors to the phospholipid phosphatidylserine increases their sensitivity to dopamine in aged rats 58
A1-42 fragment induces an up-regulation of NCX3 activity that prevents caspase-12 activation. 58
Endoplasmic reticulum refilling and mitochondrial calcium extrusion promoted in neurons by NCX1 and NCX3 in ischemic preconditioning are determinant for neuroprotection 58
Resveratrol treatment reduces the vulnerability of SH-SY5Y cells and cortical neurons overexpressing SOD1-G93A to Thimerosal toxicity through SIRT1/DREAM/PDYN pathway 58
Totale 7.573
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Categoria #
all - tutte 56.817
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 56.817
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020154 0 0 0 0 0 0 0 0 0 0 0 154
2020/2021726 40 61 59 60 78 128 57 21 69 17 93 43
2021/20221.515 27 1 5 14 14 63 13 50 237 113 379 599
2022/20231.674 289 161 49 103 189 156 12 124 197 289 74 31
2023/20241.422 61 167 138 94 71 128 24 392 2 32 209 104
2024/20256.424 337 410 23 104 116 271 711 418 542 636 2.576 280
Totale 14.085