IRIS
DI RENZO, GIANFRANCO MARIA LUIGI
 Distribuzione geografica
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Continente #
AS - Asia 7.295
EU - Europa 6.626
NA - Nord America 6.503
SA - Sud America 1.080
AF - Africa 193
OC - Oceania 8
Continente sconosciuto - Info sul continente non disponibili 6
Totale 21.711
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Nazione #
US - Stati Uniti d'America 6.171
SG - Singapore 4.159
RU - Federazione Russa 3.238
CN - Cina 1.536
IT - Italia 988
BR - Brasile 883
HK - Hong Kong 710
DE - Germania 534
VN - Vietnam 495
FI - Finlandia 367
NL - Olanda 307
UA - Ucraina 299
IE - Irlanda 220
CA - Canada 212
GB - Regno Unito 211
SE - Svezia 145
FR - Francia 119
AR - Argentina 81
IN - India 78
MX - Messico 78
CI - Costa d'Avorio 76
PL - Polonia 61
TR - Turchia 47
JP - Giappone 45
BD - Bangladesh 44
ES - Italia 42
ZA - Sudafrica 40
EC - Ecuador 31
IQ - Iraq 30
ID - Indonesia 29
CL - Cile 19
PE - Perù 16
MA - Marocco 15
UZ - Uzbekistan 15
LT - Lituania 14
VE - Venezuela 14
AT - Austria 13
BE - Belgio 13
PY - Paraguay 13
CO - Colombia 11
PK - Pakistan 11
KE - Kenya 10
IL - Israele 9
SA - Arabia Saudita 9
EG - Egitto 8
IR - Iran 8
AE - Emirati Arabi Uniti 7
CH - Svizzera 7
CZ - Repubblica Ceca 7
JM - Giamaica 7
NP - Nepal 7
AL - Albania 6
UY - Uruguay 6
AU - Australia 5
AZ - Azerbaigian 5
BG - Bulgaria 5
JO - Giordania 5
KR - Corea 5
MY - Malesia 5
TN - Tunisia 5
DO - Repubblica Dominicana 4
DZ - Algeria 4
EU - Europa 4
GA - Gabon 4
GP - Guadalupe 4
GT - Guatemala 4
HU - Ungheria 4
KG - Kirghizistan 4
KZ - Kazakistan 4
ME - Montenegro 4
NO - Norvegia 4
BO - Bolivia 3
CR - Costa Rica 3
GR - Grecia 3
LB - Libano 3
NG - Nigeria 3
OM - Oman 3
RS - Serbia 3
SN - Senegal 3
TH - Thailandia 3
ZM - Zambia 3
AF - Afghanistan, Repubblica islamica di 2
AO - Angola 2
BY - Bielorussia 2
CG - Congo 2
CM - Camerun 2
CY - Cipro 2
GE - Georgia 2
HN - Honduras 2
IS - Islanda 2
KH - Cambogia 2
LA - Repubblica Popolare Democratica del Laos 2
MU - Mauritius 2
NC - Nuova Caledonia 2
NI - Nicaragua 2
PA - Panama 2
PR - Porto Rico 2
SI - Slovenia 2
SR - Suriname 2
TT - Trinidad e Tobago 2
Totale 21.668
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Città #
Singapore 1.849
Moscow 778
Ashburn 750
Hong Kong 693
Chandler 674
Beijing 521
Millbury 307
Jacksonville 306
Amsterdam 288
Princeton 267
Santa Clara 265
Los Angeles 236
Nanjing 194
Ho Chi Minh City 170
Napoli 167
Naples 145
Ottawa 140
Boston 121
Munich 119
Buffalo 117
Hanoi 112
New York 105
Wilmington 98
São Paulo 86
Redondo Beach 75
The Dalles 70
Nanchang 69
Seattle 63
Turku 63
Hefei 55
Warsaw 55
Dallas 54
Norwalk 46
Brooklyn 44
Helsinki 43
Changsha 41
Tokyo 39
Dearborn 38
Mexico City 37
Des Moines 36
London 36
Shenyang 36
Hebei 35
Chicago 34
Falls Church 34
Chennai 32
Montreal 32
Poplar 32
Rome 31
Stockholm 30
Tianjin 30
Denver 29
Houston 28
San Jose 28
Dong Ket 26
Falkenstein 26
Milan 26
Orem 26
Phoenix 26
Woodbridge 26
Atlanta 25
Frankfurt am Main 23
Johannesburg 23
Formia 22
Ankara 21
Haiphong 21
Jiaxing 21
Toronto 21
Washington 21
Caserta 20
Orange 19
Belo Horizonte 18
Kunming 18
Rio de Janeiro 18
Da Nang 17
Kronberg 17
San Francisco 17
Curitiba 16
Manchester 16
Ninh Bình 15
Augusta 14
Brasília 13
Guangzhou 13
Tashkent 13
Biên Hòa 12
Dublin 12
Hangzhou 12
Palermo 12
Redwood City 12
Jakarta 11
Jinan 11
Querétaro 11
Zhengzhou 11
Baghdad 10
Buenos Aires 10
Campinas 10
Frattaminore 10
Ningbo 10
Nuremberg 10
Paris 10
Totale 10.555
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Nome #
7-nitro-5-fenil-1(pirrolidin-1-ilmetil)-1H-benzo[e][1,4] diazepin-2(3H)-one ed altri composti derivati delle benzodiazepine 375
Trattato di Farmacologia 262
Pharmacological characterization of the newly synthesized 5-amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide hydrochloride (BED) as a potent NCX3 inhibitor that worsens anoxic injury in cortical neurons, organotypic hippocampal cultures, and ischemic brain 163
Triticum vulgare extract exerts an anti-inflammatory action in two in vitro models of inflammation in microglial cells 157
Na+/Ca2+ exchanger 1 on nuclear envelope controls PTEN/Akt pathway via nucleoplasmic Ca2+ regulation during neuronal differentiation 152
The antiepileptic drug levetiracetam suppresses non-convulsive seizure activity and reduces ischemic brain damage in rats subjected to permanent middle cerebral artery occlusion 147
Sp3/REST/HDAC1/HDAC2 complex represses and Sp1/HIF-1/p300 complex activates ncx1 gene transcription, in brain ischemia and in ischemic brain preconditioning, by Epigenetic mechanism 145
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 142
The miR206-JunD circuit mediates the neurotoxic effect of methylmercury in cortical neurons 140
ncx1, ncx2, and ncx3 gene product expression and function in neuronal anoxia and brain ischemia. 139
The functional coupling between endoplasmic reticulum and lysosomes for intracellular Ca2+ handling is disrupted in brain ischemia 139
Acute and long-term NCX activation reduces brain injury and restores behavioral functions in mice subjected to neonatal brain ischemia 138
L’aumento dell’RNAm e della proteina HIF-1α, una subunità della proteina Hypoxia Inducible Factor (HIF-1), indotta dall’ischemia cerebrale, attiva il gene codificante per la iNOS 136
Successful treatment of post-surgical osteomyelitis caused by XDR Pseudomonas aeruginosa with ceftolozane/tazobactam monotherapy 136
A critical role for the potassium-dependent sodium-calcium exchanger NCKX2 in protection against focal ischemic brain damage. 135
The expression and activity of KV3.4 channel subunits are precociously upregulated in astrocytes exposed to Aβ oligomers and in astrocytes of Alzheimer's disease Tg2576 mice 135
NCX1 is a new rest target gene: role in cerebral ischemia 134
BHK cells transfected with NCX3 are more resistant to hypoxia followed by reoxygenation than those transfected with NCX1 and NCX2: Possible relationship with mitochondrial membrane potential 133
Involvement of the Na+/Ca2+ exchanger isoform 1 (NCX1) in neuronal growth factor (NGF)-induced neuronal differentiation through Ca2+-dependent Akt phosphorylation 133
Methylmercury upregulates RE-1 silencing transcription factor (REST) in SH-SY5Y cells and mouse cerebellum 133
Genetically modified mice as a strategy to unravel the role played by the na(+)/ca (2+) exchanger in brain ischemia and in spatial learning and memory deficits 130
L’aumento dell’mRNA e della proteina HIF-1a, una subunità della proteina HIF-1 (Hypoxia Inducible Factor), indotta dall’ischemia cerebrale, attiva il gene codificante per la iNOS 128
Preconditioning, induced by sub-toxic dose of the neurotoxin L-BMAA, delays ALS progression in mice and prevents Na+/Ca2+exchanger 3 downregulation 127
A New Cell-penetrating Peptide That Blocks the Autoinhibitory XIP Domain of NCX1 and Enhances Antiporter Activity 125
Neuronal NCX1 overexpression induces stroke resistance while knockout induces vulnerability via Akt 125
ApoSOD1 lacking dismutase activity neuroprotects motor neurons exposed to beta-methylamino-L-alanine through the Ca(2+)/Akt/ERK1/2 prosurvival pathway 125
Neuroprotective Effect of VEGF-Mimetic Peptide QK in Experimental Brain Ischemia Induced in Rat by Middle Cerebral Artery Occlusion 124
Involvement of PI3'-K, mitogen-activated protein kinase and protein kinase B in the up-regulation of the expression of nNOSalpha and nNOSbeta splicing variants induced by PRL-receptor activation in GH3 cells 121
Involvement of the nitric oxide/protein kinase G pathway in polychlorinated biphenyl-induced cell death in SH-SY 5Y neuroblastoma cells 120
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions 118
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 117
Cigarette Smoke Condensate Causes a Decrease of the Gene Expression of Cu-Zn Superoxide Dismutase, Mn Superoxide Dismutase, Glutathione Peroxidase, Catalase, and Free Radical-Induced Cell Injury in SH-SY5Y Human Neuroblastoma Cells 117
'Janus face' of nitric oxide action on plasma membrane and intracellular ionic channels. 116
p38/Sp1/Sp4/HDAC4/BDNF Axis Is a Novel Molecular Pathway of the Neurotoxic Effect of the Methylmercury 115
Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage. 114
Aβ1-42 fragment induces an up-regulation of NCX3 activity that prevents caspase-12 activation 114
The modulation of intracellular Ca2+ homeostasis is involved in SOD1 and ApoSOD1-induced neuroprotection of motor neurons exposed to beta-methylamino-L-alanine 114
ASIC1a contributes to neuroprotection elicited by ischemic preconditioning and postconditioning 113
Histone deacetylase 4 promotes ubiquitin-dependent proteasomal degradation of Sp3 in SH-SY5Y cells treated with di(2-ethylhexyl)phthalate (DEHP), determining neuronal death. 112
Resveratrol via sirtuin-1 downregulates RE1-silencing transcription factor (REST) expression preventing PCB-95-induced neuronal cell death 112
Genetic Up-Regulation or Pharmacological Activation of the Na+/Ca2+ Exchanger 1 (NCX1) Enhances Hippocampal-Dependent Contextual and Spatial Learning and Memory 112
Pure uptake blockers of dopamine can reduce prolactin secretion: studies with diclofensine 111
NCX1 Is a Novel Target Gene for Hypoxia-Inducible Factor-1 in Ischemic Brain Preconditioning 111
7-nitro-5-phenyl-1-(pyrrolidin-1-ylmethyl)-1H-benzo[E][1,4]diazepin-2(3H)-one and other benzodiazepine derivatives 111
Sumoylation of LYS590 of NCX3 f-Loop by SUMO1 Participates in Brain Neuroprotection Induced By Ischemic Preconditioning 111
BHK cells transfected with NCX3 are more resistant to hypoxia followed by reoxygenation than those transfected with NCX1 and NCX2: Possible relationship with mitochondrial membrane potential. 110
Antithrombin reduces ischemic volume, ameliorates neurologic deficits, and prolongs animal survival in both transient and permanent focal ischemia 110
Molecular pharmacology of the amiloride analog 3-amino-6-chloro-5-[(4-chloro-benzyl)amino]-n-[[(2,4-dimethylbenzyl)-amino]iminomethyl]-pyrazinecarboxamide (CB-DMB) as a pan inhibitor of the Na+-Ca2+ exchanger isoforms NCX1, NCX2, and NCX3 in stably transfected cells 110
HDAC4 and HDAC5 form a complex with DREAM that epigenetically down-regulates NCX3 gene and its pharmacological inhibition reduces neuronal stroke damage 110
Evidence for a protective role played by Na+-Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats 109
The Na+/Ca2+ exchanger isoform 3 (NCX3) but not isoform 2 (NCX2) and 1 (NCX1) singly transfected in BHK cells plays a protective role in a model of in vitro hypoxia 109
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 108
Differential Vulnerability of Cortical and Cerebellar Neurons in Primary Culture to Oxygen Glucose Deprivation followed by Reoxygenation. 108
Effects of manidipine and nitrendipine enantiomers on the plateau phase of K+-induced intracellular Ca2+ increase in GH3 cells. 108
A1-42 fragment induces an up-regulation of NCX3 activity that prevents caspase-12 activation. 108
. Ab1-42 fragment induces an up-regulation of NCX3 activity that prevents caspase-12 activation. 108
Polychlorinated biphenyls impair dibutyryl cAMP-induced astrocytic differentiation in rat C6 glial cell line 108
MS-275 inhibits aroclor 1254-induced SH-SY5Y neuronal cell toxicity by preventing the formation of the HDAC3/REST complex on the synapsin-1 promoter 108
Modulation of ion channels by reactive oxygen and nitrogen species: a pathophysiological role in brain aging? 107
Does Na(+)/Ca (2+) Exchanger, NCX, Represent a New Druggable Target in Stroke Intervention? 107
A1-42 fragment induces an up-regulation of NCX3 activity that prevents caspase-12 activation. 105
Transcriptional Regulation of ncx1 Gene in the Brain 105
pharmacological blockade of ERG K+ channels and Ca2+ influx through store-operated channels exerts opposite effects on intracellular Ca2+ oscillations in pituitary gh3 cells 104
Anoxia-induced NF-kappaB-dependent upregulation of NCX1 contributes to Ca2+ refilling into endoplasmic reticulum in cortical neurons 104
Imatinib-Mesylate Blocks Recombinant T-Type Calcium Channels Expressed In Hek-293 Cells By A Ptk-Independent Mechanism 103
Two sodium/calcium exchanger gene products, NCX1 and NCX3, play a major role in the development of permanent focal cerebral ischemia. 103
Nitric oxide stimulates NCX1 and NCX2 but inhibits NCX3 isoform by three distinct molecular determinants 103
Involvement of Na+-Ca2+ exchanger in intracellular Ca2+ increase and neuronal injury induced by polychlorinated biphenyls in human neuroblastoma SH-SY5Y cells 102
Endoplasmic reticulum refilling and mitochondrial calcium extrusion promoted in neurons by NCX1 and NCX3 in ischemic preconditioning are determinant for neuroprotection 102
NCX1 and NCX3: Two new effectors of delayed preconditioning in brain ischemia 101
MC1568 Inhibits Thimerosal-Induced Apoptotic Cell Death by Preventing HDAC4 Up-Regulation in Neuronal Cells and in Rat Prefrontal Cortex 101
Na+/Ca2+ exchanger in Na+ efflux-Ca2+ influx mode of operation exerts a neuroprotective role in cellular models of in vitro anoxia and in vivo cerebral ischemia. 100
Uso dell'Antitrombina III (ATIII) per la preparazione di formulazioni farmaceutiche per uso parenterale per il trattamento dei danni cerebrali secondari all'insulto ischemico o ad altre malattie degenerative del sistema nervoso centrale e periferico 100
Uso dell'Antitrombina III (ATIII) per la preparazione di formulazioni farmaceutiche per uso parenterale per il trattamento dei danni cerebrali secondari all'insulto ischemico o ad altre malattie del sistema nervoso centrale e periferico 100
Ionic homeostasis in brain conditioning 100
NCX1 and NCX3 as potential factors contributing to neurodegeneration and neuroinflammation in the A53T transgenic mouse model of Parkinson's Disease 100
HIF-1 alpha reveals a binding- activity to the promoter of iNOS gene after permanent middle cerebral artery occlusion 99
Up-regulation and increased activity of KV3.4 channels and their accessory subunit MinK-related peptide 2 induced by amyloid peptide are involved in apoptotic neuronal death 99
Conjunctival instillation of plasminogen eliminates ocular lesion in B6.129P2-Plg(tm1Jld) transgenic mice, a model of ligneous conjunctivitis 99
Neuroprotective Role of Sodium/Calcium Exchanger, NCX1 and NCX3, in Ischemic Preconditioning 98
Alcohol increases spontaneous BOLD signal fluctuations in the visual network 98
Ca2+-independent caspase-3 but not ca2+-dependent caspase-2 activation induced by oxidative stress leads to SH-SY5Y human neuroblastoma cell apoptosis 97
Neuronal NOS activation during oxygen and glucose deprivation triggers cerebellar granule cell death in the later reoxygenation phase 97
NO-induced neuroprotection in ischemic preconditioning stimulates mitochondrial Mn-SOD activity and expression via Ras/ERK1/2 pathway 97
The NCX3 isoform of the Na(+)/Ca(2+) exchanger contributes to neuroprotection elicited by ischemic postconditioning 97
L’ipossia modula in maniera opposta l’attività di RNA-binding di IRP1 e l’espressione della ferritina in neuroni corticali e cellule gliali 97
Differential vulnerability of cortical and cerebellar neurons in primary culture to oxygen deprivation followed by reoxygenation 96
Clinical Trials with Drugs Targeting Ionic Channels, Antiporters, and Pumps in Ischemic Stroke 96
Neurounina-1, a Novel Compound that Increases Na+/Ca2+ Exchanger Activity, Effectively Protects Against Stroke Damage 96
Antihypertensive response to combination of olmesartan and amlodipine does not depend on method and time of drug administration. 96
Unique Scopolamine Withdrawal Syndrome After Standard Transdermal Use 96
Effects of tartrate thyrotropin-releasing hormone treatment on serum thyrotropin, free triiodothyronine, free thyroxine and prolactin levels in patients with spinocerebellar degeneration 95
A new concept: Aβ1-42 generates a hyperfunctional proteolytic NCX3 fragment that delays caspase-12 activation and neuronal death 95
New insights in mitochondrial calcium handling by sodium/calcium exchanger 95
The neurotoxicant PCB-95 by increasing the neuronal transcriptional repressor REST down-regulates caspase-8 and increases Ripk1, Ripk3 and MLKL expression determining necroptotic neuronal death 95
Resveratrol treatment reduces the vulnerability of SH-SY5Y cells and cortical neurons overexpressing SOD1-G93A to Thimerosal toxicity through SIRT1/DREAM/PDYN pathway 95
The 2-oxopyrrolidinacetamide piracetam reduces infarct brain volume induced by permanent middle cerebral artery occlusion in male rats. 94
Zn(2+) slows down Ca(V)3.3 gating kinetics: implications for thalamocortical activity. 94
Lack of evidence for an inhibitory role played by tuberoinfundibular dopaminergic neurons on TSH secretion in the rat. 94
Differential vulnerability of cortical and cerebellar neurons in primary culture to oxygen glucose deprivation followed by reoxygenation 94
Totale 11.687
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Categoria #
all - tutte 74.423
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 74.423
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021300 0 0 0 0 0 0 57 21 69 17 93 43
2021/20221.515 27 1 5 14 14 63 13 50 237 113 379 599
2022/20231.674 289 161 49 103 189 156 12 124 197 289 74 31
2023/20241.422 61 167 138 94 71 128 24 392 2 32 209 104
2024/20256.752 337 410 23 104 116 271 711 418 542 636 2.576 608
2025/20267.623 1.524 639 1.290 1.286 2.350 506 28 0 0 0 0 0
Totale 22.036