IRIS
GALIETTA, Luis Juan Vicente
 Distribuzione geografica
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Continente #
AS - Asia 4.507
NA - Nord America 3.291
EU - Europa 2.490
SA - Sud America 619
AF - Africa 57
OC - Oceania 8
Continente sconosciuto - Info sul continente non disponibili 5
Totale 10.977
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Nazione #
US - Stati Uniti d'America 3.149
SG - Singapore 2.576
RU - Federazione Russa 1.420
CN - Cina 940
BR - Brasile 535
HK - Hong Kong 488
IT - Italia 356
VN - Vietnam 218
NL - Olanda 184
DE - Germania 110
GB - Regno Unito 83
CA - Canada 70
SE - Svezia 62
FR - Francia 55
UA - Ucraina 54
IN - India 52
KR - Corea 45
MX - Messico 42
FI - Finlandia 34
AR - Argentina 33
BD - Bangladesh 30
IE - Irlanda 30
JP - Giappone 24
TR - Turchia 22
ID - Indonesia 20
PL - Polonia 16
ZA - Sudafrica 16
AT - Austria 14
ES - Italia 14
EC - Ecuador 13
SA - Arabia Saudita 13
CO - Colombia 12
BE - Belgio 10
IL - Israele 10
IQ - Iraq 8
CI - Costa d'Avorio 7
MA - Marocco 7
PK - Pakistan 7
UZ - Uzbekistan 7
CL - Cile 6
CR - Costa Rica 6
DO - Repubblica Dominicana 6
JO - Giordania 6
PY - Paraguay 6
UY - Uruguay 6
DK - Danimarca 5
HN - Honduras 5
IR - Iran 5
VE - Venezuela 5
AU - Australia 4
KZ - Kazakistan 4
MD - Moldavia 4
MY - Malesia 4
RO - Romania 4
TN - Tunisia 4
TT - Trinidad e Tobago 4
AF - Afghanistan, Repubblica islamica di 3
AL - Albania 3
BG - Bulgaria 3
CZ - Repubblica Ceca 3
EU - Europa 3
HR - Croazia 3
HU - Ungheria 3
KE - Kenya 3
LT - Lituania 3
PE - Perù 3
PT - Portogallo 3
AE - Emirati Arabi Uniti 2
AZ - Azerbaigian 2
BY - Bielorussia 2
CH - Svizzera 2
CY - Cipro 2
DZ - Algeria 2
EG - Egitto 2
GN - Guinea 2
GT - Guatemala 2
KH - Cambogia 2
KW - Kuwait 2
NC - Nuova Caledonia 2
OM - Oman 2
PA - Panama 2
RS - Serbia 2
TH - Thailandia 2
XK - ???statistics.table.value.countryCode.XK??? 2
AO - Angola 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BF - Burkina Faso 1
BN - Brunei Darussalam 1
BT - Bhutan 1
BW - Botswana 1
BZ - Belize 1
CM - Camerun 1
CV - Capo Verde 1
DM - Dominica 1
EE - Estonia 1
ET - Etiopia 1
GE - Georgia 1
GH - Ghana 1
GR - Grecia 1
Totale 10.953
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Città #
Singapore 1.136
Chandler 490
Hong Kong 487
Moscow 389
Ashburn 283
Santa Clara 261
Hefei 230
Beijing 172
Amsterdam 167
Lawrence 166
Nanjing 143
Des Moines 132
Naples 129
Boston 115
Millbury 108
Los Angeles 101
Redondo Beach 78
Ho Chi Minh City 68
Buffalo 67
Hanoi 57
São Paulo 52
Napoli 51
Seoul 45
Ottawa 36
Shenyang 35
The Dalles 34
Hebei 33
Dallas 32
New York 30
Nanchang 29
Wilmington 28
Chicago 26
Changsha 24
Jiaxing 24
Seattle 23
Frankfurt am Main 21
Mexico City 21
Munich 21
Dublin 20
Rio de Janeiro 19
Washington 19
Nuremberg 18
San Jose 18
Tokyo 18
Helsinki 17
Orem 17
Milan 16
Stockholm 16
Columbus 15
Tianjin 15
Jacksonville 14
Warsaw 14
Atlanta 13
Belo Horizonte 13
Montreal 13
Brighton 12
Johannesburg 12
Poplar 12
Edinburgh 11
Brasília 10
Shanghai 10
Brooklyn 9
Brussels 9
Curitiba 9
London 9
Biên Hòa 8
Chennai 8
Dhaka 8
Haiphong 8
Melito di Napoli 8
Paris 8
Riyadh 8
San Francisco 8
Tel Aviv 8
Toronto 8
Vienna 8
Ankara 7
Bengaluru 7
Denver 7
Düsseldorf 7
Lappeenranta 7
Manchester 7
Marigliano 7
Tashkent 7
Amman 6
Boardman 6
Caxias do Sul 6
Franca 6
Houston 6
Istanbul 6
Kronberg 6
Manaus 6
Miami 6
Mumbai 6
Turku 6
Vinh 6
Fairfield 5
Falkenstein 5
Hải Dương 5
Maceió 5
Totale 5.958
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Nome #
3-(2-Benzyloxyphenyl)isoxazoles and isoxazolines: synthesis and evaluation as CFTR activators 165
Light-responsive microRNA miR-211 targets Ezrin to modulate lysosomal biogenesis and retinal cell clearance 165
A chloride conductance evoked by hypotonic shock in epithelial cells 127
A functional 3D full-thickness model for comprehending the interaction between airway epithelium and connective tissue in cystic fibrosis 127
Pharmacological potentiators of the calcium signaling cascade identified by high-throughput screening 125
Analysis of inhibitors of the anoctamin-1 chloride channel (transmembrane member 16A, TMEM16A) reveals indirect mechanisms involving alterations in calcium signalling 108
Assessing the Potential of N-Butyl-l-deoxynojirimycin (l-NBDNJ) in Models of Cystic Fibrosis as a Promising Antibacterial Agent 105
Functional restoration of a CFTR splicing mutation through RNA delivery of CRISPR adenine base editor 103
High-throughput screening identifies FAU protein as a regulator of mutant cystic fibrosis transmembrane conductance regulator channel 100
Rheological Properties of Cystic Fibrosis Bronchial Secretion and in Vitro Drug Permeation Study: The Effect of Sodium Bicarbonate 100
Novel tricyclic pyrrolo-quinolines as pharmacological correctors of the mutant CFTR chloride channel 98
Airway surface hyperviscosity and defective mucociliary transport by IL-17/TNF-α are corrected by beta-adrenergic stimulus 98
Two CFTR mutations within codon 970 differently impact on the chloride channel functionality 96
The role of functional studies in the diagnosis and treatment of Cystic Fibrosis: comparing the case of the G970D and G970R mutation. 94
Pharmacoproteomics pinpoints HSP70 interaction for correction of the most frequent Wilson disease-causing mutant of ATP7B 93
Ionocytes and CFTR Chloride Channel Expression in Normal and Cystic Fibrosis Nasal and Bronchial Epithelial Cells 91
High-throughput screening for modulators of ACVR1 transcription: Discovery of potential therapeutics for fibrodysplasia ossificans progressiva 89
A novel missense mutation in ANO5/TMEM16E is causative for gnathodiaphyseal dyplasia in a large Italian pedigree 89
Unravelling druggable signalling networks that control F508del-CFTR proteostasis 88
Development of the olfactory epithelium and Nasal Glands in TMEM16A-/-and TMEM16A+/ +Mice 88
Easy-to-Build and Reusable Microfluidic Device for the Dynamic Culture of Human Bronchial Cystic Fibrosis Epithelia 87
Upregulation of TMEM16A protein in bronchial epithelial cells by bacterial pyocyanin 87
The ubiquitin ligase tripartite-motif-protein 32 is induced in Duchenne muscular dystrophy 86
Genetic Inhibition of the Ubiquitin Ligase Rnf5 Attenuates Phenotypes Associated to F508del Cystic Fibrosis Mutation 86
Targeting ion channels in cystic fibrosis 86
Functional analysis of acid-activated Cl- channels: Properties and mechanisms of regulation 85
Covid-19 in cystic fibrosis patients compared to the general population: Severity and virus-host cell interactions 84
Goblet Cell Hyperplasia Requires High Bicarbonate Transport to Support Mucin Release 84
The extracellular calcium-sensing receptor regulates human fetal lung development via CFTR 84
Novel Hits in the Correction of δf508-Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Protein: Synthesis, Pharmacological, and ADME Evaluation of Tetrahydropyrido[4,3-d]pyrimidines for the Potential Treatment of Cystic Fibrosis 83
Identification and characterization of a novel promoter for the human ANO1 gene regulated by the transcription factor signal transducer and activator of transcription 6 (STAT6) 82
Phenylhydrazones as Correctors of a Mutant Cystic Fibrosis Transmembrane Conductance Regulator 82
Distinct Responses of Cystic Fibrosis Epithelial Cells to SARS-CoV-2 and Influenza A Virus 81
A minimal isoform of the TMEM16A protein associated with chloride channel activity 80
Synthesis and structure-activity relationship of aminoarylthiazole derivatives as correctors of the chloride transport defect in cystic fibrosis 80
Effect of inflammatory stimuli on airway ion transport 80
TRPV4 and purinergic receptor signalling pathways are separately linked in airway epithelia to CFTR and TMEM16A chloride channels 80
Pharmacological rescue of mutant CFTR protein improves the viscoelastic properties of CF mucus 79
A European regulatory perspective on cystic fibrosis: Current treatments, trends in drug development and translational challenges for CFTR modulators 78
Ion channel and lipid scramblase activity associated with expression of TMEM16F/ANO6 isoforms 77
Partial rescue of f508del-cftr stability and trafficking defects by double corrector treatment 77
Pharmacological analysis of epithelial chloride secretion mechanisms in adult murine airways 76
Esculentin-1a-derived peptides promote clearance of pseudomonas aeruginosa internalized in bronchial cells of cystic fibrosis patients and lung cell migration: Biochemical properties and a plausible mode of action 76
The L467F-F508del Complex Allele Hampers Pharmacological Rescue of Mutant CFTR by Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis Patients: The Value of the Ex Vivo Nasal Epithelial Model to Address Non-Responders to CFTR-Modulating Drugs 75
Altered expression of ano1 variants in human diabetic gastroparesis 75
Phenylglycine and sulfonamide correctors of defective ΔF508 and G551D cystic fibrosis transmembrane conductance regulator chloride-channel gating 74
Intrinsic Abnormalities of Cystic Fibrosis Airway Connective Tissue Revealed by an In Vitro 3D Stromal Model 70
The apical mucus layer alters the pharmacological properties of the airway epitheliumy 69
Altered channel gating mechanism for CFTR inhibition by a high-affinity thiazolidinone blocker 69
Airway surface liquid acidification initiates host defense abnormalities in Cystic Fibrosis 69
Volume-sensitive chloride currents in four epithelial cell lines are not directly correlated to the expression of the MDR-1 gene 68
Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia 68
A large conductance Cl- channel revealed by patch-recordings in human fibroblasts 66
Functional rescue of F508del-CFTR through revertant mutations introduced by CRISPR base editing 63
Biophysical characteristics of swelling-activated Cl- channels in human tracheal 9HTEo-cells 63
Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion 63
Activation of G551D CFTR channel with MPB-91: regulation by ATPase activity and phosphorylation 62
KCa3.1 differentially regulates trachea and bronchi epithelial gene expression in a chronic-asthma mouse model 61
The Autophagy Inhibitor Spautin-1 Antagonizes Rescue of Mutant CFTR Through an Autophagy-Independent and USP13-Mediated Mechanism 61
Characterization of the human gene coding for the swelling-dependent chloride channel ICln at position 11q13.5-14.1 (CLNS1A) and further characterization of the chromosome 6 (CLNS1B) localization 61
Association of TMEM16A chloride channel overexpression with airway goblet cell metaplasia 61
ATP and A1 adenosine receptor agonists mobilize intracellular calcium and activate K+ and Cl- currents in normal and cystic fibrosis airway epithelial cells 59
TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity 59
Regulation of TMEM16A chloride channel properties by alternative splicing 59
Antihypertensive 1,4-dihydropyridines as correctors of the cystic fibrosis transmembrane conductance regulator channel gating defect caused by cystic fibrosis mutations 59
Why is the cystic fibrosis gene so frequent? 59
Airway microenvironment alterations and pathogen growth in cystic fibrosis 58
Correction of delF508-CFTR activity with benzo(c)quinolizinium compounds through facilitation of its processing in cystic fibrosis airway cells 58
Mutation-specific potency and efficacy of cystic fibrosis transmembrane conductance regulator chloride channel potentiators 57
Regulation of taurine transport in murine macrophages 57
Evidence for direct CFTR inhibition by CFTRinh-172 based on Arg347 mutagenesis 57
A class of non-selective cation channels in human fibroblasts 57
Substituted 2-Acylaminocycloalkylthiophene-3-carboxylic Acid Arylamides as Inhibitors of the Calcium-Activated Chloride Channel Transmembrane Protein 16A (TMEM16A) 56
Lectin Conjugates as Potent, Nonabsorbable CFTR Inhibitors for Reducing Intestinal Fluid Secretion in Cholera 56
Volume regulatory taurine release in human tracheal 9HTEo- and multidrug resistant 9HTEo-/Dx cells 56
CFTR chloride channel drug discovery--inhibitors as antidiarrheals and activators for therapy of cystic fibrosis 56
Author Correction: Airway surface liquid acidification initiates host defense abnormalities in Cystic Fibrosis (Scientific Reports, (2019), 9, 1, (6516), 10.1038/s41598-019-42751-4) 56
Increased expression of ATP12A proton pump in cystic fibrosis airways 55
α-aminoazaheterocyclic-methylglyoxal adducts do not inhibit cystic fibrosis transmembrane conductance regulator chloride channel activity 55
Alternative splicing at a NAGNAG acceptor site as a novel phenotype modifier 55
Dual activity of aminoarylthiazoles on the trafficking and gating defects of the cystic fibrosis transmembrane conductance regulator chloride channel caused by cystic fibrosis mutations 55
Combination potentiator (‘co-potentiator’) therapy for CF caused by CFTR mutants, including N1303K, that are poorly responsive to single potentiators 54
DOG1 regulates growth and IGFBP5 in gastrointestinal stromal tumors 54
An overview on chemical structures as ΔF508-CFTR correctors 54
Sodium-Coupled Monocarboxylate Absorption in the Airway Epithelium Is Facilitated by the SLC5A8 Co-Transporter 53
TMEM16A (ANO1) as a therapeutic target in cystic fibrosis 53
Autocrine regulation of volume-sensitive anion channels in airway epithelial cells by adenosine 53
Activation of Ca(2+)-dependent K+ and Cl- currents by UTP and ATP in CFPAC-1 cells 53
Ex vivo model predicted in vivo efficacy of CFTR modulator therapy in a child with rare genotype 53
A volume-sensitive chloride conductance revealed in cultured human keratinocytes by 36Cl- efflux and whole-cell patch clamp recording 52
Synthesis of 4-thiophen-2′-yl-1,4-dihydropyridines as potentiators of the CFTR chloride channel 52
Modulation of HLA-DR antigen and ICAM-1 molecule expression on airway epithelial cells by sodium nedocromil 51
Alternative Splicing of In-Frame Exon Associated with Premature Termination Codons: Implications for Readthrough Therapies 51
Insensitivity of volume-sensitive chloride currents to chromones in human airway epithelial cells 51
Cl- currents activated by extracellular nucleotides in human bronchial cells 51
Gelsolin secretion in interleukin-4-treated bronchial epithelia and in asthmatic airways 51
Small-molecule correctors of defective ΔF508-CFTR cellular processing identified by high-throughput screening 51
Lack of Kcnn4 improves mucociliary clearance in muco-obstructive lung disease 51
Identification, Structure-Activity Relationship, and Biological Characterization of 2,3,4,5-Tetrahydro-1H-pyrido[4,3-b]indoles as a Novel Class of CFTR Potentiators 51
High-affinity activators of cystic fibrosis transmembrane conductance regulator (CFTR) chloride conductance identified by high-throughput screening 50
Totale 7.355
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Categoria #
all - tutte 39.922
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 39.922
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202180 0 0 0 0 0 0 10 5 30 11 14 10
2021/2022560 5 1 2 8 30 28 4 23 20 7 57 375
2022/20231.300 176 48 12 129 140 152 12 154 224 122 110 21
2023/2024723 36 145 116 73 34 48 27 32 6 6 128 72
2024/20253.782 235 263 20 23 42 312 448 231 407 380 1.110 311
2025/20264.104 798 611 784 508 1.092 264 47 0 0 0 0 0
Totale 11.217