IRIS
NICOSIA, Alfredo
 Distribuzione geografica
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Continente #
AS - Asia 5.340
NA - Nord America 4.417
EU - Europa 3.009
SA - Sud America 632
AF - Africa 113
OC - Oceania 4
Continente sconosciuto - Info sul continente non disponibili 2
Totale 13.517
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Nazione #
US - Stati Uniti d'America 4.198
SG - Singapore 2.417
RU - Federazione Russa 1.461
CN - Cina 960
VN - Vietnam 955
BR - Brasile 516
HK - Hong Kong 508
IT - Italia 429
FR - Francia 187
DE - Germania 171
IE - Irlanda 171
FI - Finlandia 154
NL - Olanda 143
CA - Canada 139
GB - Regno Unito 125
JP - Giappone 88
IN - India 87
BD - Bangladesh 52
AR - Argentina 44
MX - Messico 43
IQ - Iraq 34
CI - Costa d'Avorio 32
KR - Corea 31
AT - Austria 28
SE - Svezia 26
PK - Pakistan 25
ZA - Sudafrica 25
EC - Ecuador 24
TH - Thailandia 24
PH - Filippine 22
ID - Indonesia 19
ES - Italia 17
PL - Polonia 17
TR - Turchia 17
UA - Ucraina 15
CO - Colombia 13
TW - Taiwan 13
JO - Giordania 12
RO - Romania 11
UZ - Uzbekistan 11
TN - Tunisia 10
VE - Venezuela 10
CL - Cile 9
JM - Giamaica 9
LT - Lituania 9
BE - Belgio 8
AE - Emirati Arabi Uniti 7
CH - Svizzera 7
DZ - Algeria 7
EG - Egitto 7
PY - Paraguay 7
ET - Etiopia 6
IL - Israele 6
LB - Libano 6
AZ - Azerbaigian 5
HN - Honduras 5
KE - Kenya 5
OM - Oman 5
SA - Arabia Saudita 5
AL - Albania 4
NP - Nepal 4
RS - Serbia 4
UY - Uruguay 4
BO - Bolivia 3
CR - Costa Rica 3
GE - Georgia 3
LK - Sri Lanka 3
LV - Lettonia 3
MA - Marocco 3
MY - Malesia 3
NG - Nigeria 3
NI - Nicaragua 3
PA - Panama 3
AM - Armenia 2
AO - Angola 2
AU - Australia 2
BB - Barbados 2
BF - Burkina Faso 2
BG - Bulgaria 2
BH - Bahrain 2
BS - Bahamas 2
GH - Ghana 2
MD - Moldavia 2
NO - Norvegia 2
NZ - Nuova Zelanda 2
PS - Palestinian Territory 2
PT - Portogallo 2
QA - Qatar 2
SI - Slovenia 2
SN - Senegal 2
ZW - Zimbabwe 2
AF - Afghanistan, Repubblica islamica di 1
BJ - Benin 1
BM - Bermuda 1
BW - Botswana 1
BY - Bielorussia 1
BZ - Belize 1
CG - Congo 1
CM - Camerun 1
CU - Cuba 1
Totale 13.488
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Città #
Singapore 1.099
San Jose 711
Hong Kong 497
Chandler 461
Moscow 356
Ashburn 309
Beijing 296
Ho Chi Minh City 251
Santa Clara 251
Hanoi 236
The Dalles 178
Naples 162
Millbury 149
Lauterbourg 142
Amsterdam 132
Los Angeles 127
Nanjing 121
Princeton 113
Boston 101
Ottawa 87
Tokyo 77
New York 71
Hefei 67
Redondo Beach 66
Des Moines 63
Buffalo 62
Munich 53
Lawrence 51
Wilmington 47
São Paulo 44
Dallas 36
Orem 34
Frankfurt am Main 33
Haiphong 33
Napoli 32
Da Nang 31
Hebei 31
Nanchang 30
Helsinki 28
Shenyang 27
Denver 23
Tianjin 23
Biên Hòa 22
Chicago 22
Jiaxing 21
London 21
Mexico City 21
Milan 21
Rio de Janeiro 21
Dearborn 20
Montreal 19
Nuremberg 19
Chennai 18
Toronto 18
Council Bluffs 17
Falkenstein 17
Brooklyn 16
Hải Dương 16
Atlanta 15
Falls Church 15
Houston 15
San Francisco 15
Baghdad 14
Changsha 14
Manchester 14
Rome 14
Seattle 14
Belo Horizonte 13
Curitiba 13
Vienna 13
Amman 12
Nha Trang 12
Norwalk 12
Pune 12
Seoul 12
Thái Bình 12
Warsaw 12
Lahore 11
Phoenix 11
Stockholm 11
Tashkent 11
City of London 10
Porto Alegre 10
Quito 10
Can Tho 9
Dhaka 9
Washington 9
Bangkok 8
Bologna 8
Erbil 8
Johannesburg 8
Lappeenranta 8
Shanghai 8
Ankara 7
Bắc Ninh 7
Kingston 7
Marano 7
New Delhi 7
Poplar 7
Salt Lake City 7
Totale 7.501
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Nome #
Generation of a novel mesothelin-targeted oncolytic herpes virus and implemented strategies for manufacturing 190
A dna/ki67-based flow cytometry assay for cell cycle analysis of antigen-specific CD8 T cells in vaccinated mice 181
Integrity of the antiviral STING-mediated DNA sensing in tumor cells is required to sustain the immunotherapeutic efficacy of herpes simplex oncolytic virus 180
A genetic vaccine encoding shared cancer neoantigens to treat tumors with microsatellite instability 177
One-Step Recovery of scFv Clones from High-Throughput Sequencing-Based Screening of Phage Display Libraries Challenged to Cells Expressing Native Claudin-1 152
Generation of a retargeted oncolytic herpes virus encoding adenosine deaminase for tumor adenosine clearance 149
Massive parallel screening of phage libraries for the generation of repertoires of human immunomodulatory monoclonal antibodies. 146
Rapid Affinity Maturation of Novel Anti-PD-L1 Antibodies by a Fast Drop of the Antigen Concentration and FACS Selection of Yeast Libraries 146
Isolation of Two Novel Human Anti-CTLA-4 mAbs with Intriguing Biological Properties on Tumor and NK Cells 145
Novel human anti-Claudin 1 monoclonal antibodies inhibit HCV infection and may synergize with anti-SRB1 mAb. 143
A long non-coding SINEUP RNA boosts semi-stable production of fully human monoclonal antibodies in HEK293E cells 143
Prime and pull of Tcell responses against cancer-exogenous antigens is effective against CPI-resistant tumors 137
Novel Human Anti-PD-L1 mAbs Inhibit Immune-Independent Tumor Cell Growth and PD-L1 Associated Intracellular Signalling 134
Home delivery of the communicator for remote monitoring of cardiac implantable devices: A multicenter experience during the covid-19 lockdown 132
New viral vectors for infectious diseases and cancer 132
Retargeted and Multi-cytokine-Armed Herpes Virus Is a Potent Cancer Endovaccine for Local and Systemic Anti-tumor Treatment 130
High-Throughput Monoclonal Antibody Discovery from Phage Libraries: Challenging the Current Preclinical Pipeline to Keep the Pace with the Increasing mAb Demand 129
MHC class II invariant chain-adjuvanted viral vectored vaccines enhances T cell responses in humans 127
Replicative conditioning of Herpes simplex type 1 virus by Survivin promoter, combined to ERBB2 retargeting, improves tumour cell-restricted oncolysis 124
Peptide nucleic acid-mediated circularization of target RNA as tool to inhibit translation 121
Chimpanzee adenovirus- and MVA-vectored respiratory syncytial virus vaccine is safe and immunogenic in adults 119
Targeting a host-cell entry factor barricades antiviral-resistant HCV variants from on-therapy breakthrough in human-liver mice 117
A phase Ia study to assess the safety and immunogenicity of new malaria vaccine candidates ChAd63 CS administered alone and with MVA CS 111
A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory 109
Longitudinal transcriptomic and genetic landscape of radiotherapy response in canine melanoma 109
Novel genetically-modified chimpanzee adenovirus and MVA-vectored respiratory syncytial virus vaccine safely boosts humoral and cellular immunity in healthy older adults 108
Chimpanzee adenoviral vectors as vaccines–challenges to move the technology into the fast lane 107
Dramatic potentiation of the antiviral activity of HIV antibodies by cholesterol conjugation. 106
Identification of biologically active peptides using random libraries displayed on phage. 105
Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling 104
Efficacy of a virus-vectored vaccine against human and bovine respiratory syncytial virus infections 103
Mucosal delivery of a vectored RSV vaccine is safe and elicits protective immunity in rodents and nonhuman primates 102
Incidence and Risk Factors for Hepatitis C Virus Infection among Illicit Drug Users in Italy 99
Derivation of vaccines from mimotopes. Immunologic properties of human hepatitis B virus surface antigen mimotopes displayed on filamentous phage. 98
Phage-displayed peptides as tools for characterization of human sera. 98
The X-ray structure of an atypical homeodomain present in the rat liver transcription factor LFB1/HNF1 and implications for DNA binding. 97
Monoclonal antibodies that recognise filamentous phage: tools for phage display technology. 97
A next generation vaccine against human rabies based on a single dose of a chimpanzee adenovirus vector serotype c 95
Promoter of the Pertussis Toxin Operon and Production of Pertussis Toxin 94
Chronic Hepatitis C Virus infection subverts vaccine induced T-cell immunity in humans 94
A Bipartite Activation Domain Is Responsible For the Activity of Transcription Factor Hnf1/lfb1 In Cells of Hepatic and Nonhepatic Origin 92
Safety and Immunogenicity of ChAd63 and MVA ME-TRAP in West African Children and Infants 92
Recognition by human sera and immunogenicity of HBsAg mimotopes selected from an M13 phage display library. 90
A Myosin-like Dimerization Helix and An Extra-large Homeodomain Are Essential Elements of the Tripartite Dna-binding Structure of Lfb1 89
Chimpanzee adenovirus vaccine generates acute and durable protective immunity against ebolavirus challenge 89
Anti body-selected mimics of hepatitis C virus hypervariable region 1 activate both primary and memory Th lymphocytes 88
Absence of systemic toxicity changes following intramuscular administration of novel pSG2.HIVconsv DNA, ChAdV63.HIVconsv and MVA.HIVconsv vaccines to BALB/c mice. 88
Peptide and protein display on the surface of filamentous bacteriophage. 86
Highly-Immunogenic Virally-Vectored T-cell Vaccines Cannot Overcome Subversion of the T-cell Response by HCV during Chronic Infection 86
Synchronous division induced in Escherichia coli K12 by gemts mutants of phage Mu. 85
A Human monoclonal antibody targeting scavenger receptor class B type I precludes hepatitis C virus infection and viral spread in vitro and in vivo 85
Epitope discovery using peptide libraries displayed on phage. 84
Anti-CD81 but not anti-SR-BI blocks Plasmodium falciparum liver infection in a humanized mouse model 84
Development of chimpanzee adenoviruses as vaccine vectors: challenges and successes emerging from clinical trials. 83
Combining viral vectored and protein-in-adjuvant vaccines against the blood-stage malaria antigen ama1: Report on a phase 1a clinical trial 83
Safety and immunogenicity of malaria vectored vaccines given with routine expanded program on immunization vaccines in gambian infants and neonates: A randomized controlled trial 83
A novel Chimpanzee serotype-based adenoviral vector as delivery tool for cancer vaccines 82
An adenovirus type 5 (Ad5) amplicon-based packaging cell line for production of high-capacity helper-independent Delta E1-E2-E3-E4 Ad5 vectors 82
Cloning and Sequencing of the Pertussis Toxin Genes - Operon Structure and Gene Duplication 81
Clinical assessment of a recombinant simian adenovirus ChAd63: a potent new vaccine vector. 81
Cloning and sequencing of the pertussis toxin genes: operon structure and gene duplication. 80
Genetic vaccination by gene electro-transfer in non-human primates 80
Safety and immunogenicity of novel respiratory syncytial virus (RSV) vaccines based on the RSV viral proteins F, N and M2-1 encoded by simian adenovirus (PanAd3-RSV) and MVA (MVA-RSV); Protocol for an open-label, dose-escalation, single-centre, phase 1 clinical trial in healthy adults 80
A general strategy to identify mimotopes of pathological antigens using only random peptide libraries and human sera. 79
Adenovirus type 4 and 7 vaccination or adenovirus type 4 respiratory infection elicits minimal cross-reactive antibody responses to nonhuman adenovirus vaccine vectors 79
A first-in-human study of the novel HIV-fusion inhibitor C34-PEG4-Chol 79
Generation of novel human anti-OX-40 mAbs endowed with different biological properties as tools for cancer therapy 78
Translating the Immunogenicity of Prime-boost Immunization With ChAd63 and MVA ME-TRAP From Malaria Naive to Malaria-endemic Populations 78
Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against Plasmodium falciparum infection in Kenyan adults 78
A novel adenovirus type 6 (Ad6)-based hepatitis C virus vector that overcomes preexisting anti-Ad5 immunity and induces potent and broad cellular immune responses in rhesus macaques 76
The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus 76
Promoter Elements and Factors Involved In Hepatic Transcription of the Human Apoa-i Gene Positive and Negative Regulators Bind To Overlapping Sites 76
Identification and Characterization of Hepatocyte-specific Regulatory Regions of the Rat Pyruvate-kinase L-gene - the Synergistic Effects of Multiple Elements 76
Immune profiling of premalignant lesions in patients with Lynch syndrome 76
Cholesterol conjugation potentiates the antiviral activity of an HIV immunoadhesin 75
Alteration In L-type Pyruvate-kinase Gene-expression Is Not Associated With the Lf-b1 Messenger-rna Level 74
Successful anti-scavenger receptor class B type I (SR-BI) monoclonal antibody therapy in humanized mice after challenge with HCV variants with in vitro resistance to SR-BI-targeting agents 74
Venus, a novel selection approach to improve the accuracy of neoantigens’ prediction 74
A T-cell HCV vaccine eliciting effective immunity against heterologous virus challenge in chimpanzees 73
Cross-reactive phage-displayed mimotopes lead to the discovery of mimicry between HSV-1 and a brain-specific protein 72
Monoclonal antibodies (mAB) with broad specificity for a large repertoire of HCV variants 72
A database system for handling phage library-derived sequences. 72
A Novel Vaccine Strategy Employing Serologically Different Chimpanzee Adenoviral Vectors for the Prevention of HIV-1 and HCV Coinfection 72
Identification of peptides binding to IgG in the CSF of multiple sclerosis patients 71
Safety and immunogenicity of heterologous prime-boost immunisation with Plasmodium falciparum malaria candidate vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in healthy Gambian and Kenyan adults. 71
Enhanced vaccine-induced CD8+ T cell responses to malaria antigen ME-TRAP by fusion to MHC class II invariant chain 71
Bacteriophage lambda display of complex cDNA libraries: A new approach to functional genomics 70
Towards a solution for hepatitis C virus hypervariability: mimotopes of the hypervariable region 1 can induce antibodies cross-reacting with a large number of viral variants 70
A complex interplay of positive and negative elements is responsible for the different transcriptional activity of liver NF1 variants. 70
Hypervariable region 1 deletion and required adaptive envelope mutations confer decreased dependency on scavenger receptor class B type I and low-density lipoprotein receptor for hepatitis C virus. 70
Chimpanzee Adenovirus Vector Ebola Vaccine - Preliminary Report 70
Human vaccination against Plasmodium vivax Duffy-binding protein induces strain-transcending antibodies 70
High-avidity monoclonal antibodies against the human scavenger class B type I receptor efficiently block hepatitis C virus infection in the presence of high-density lipoprotein 69
Multispecific T cell response and negative HCV RNA tests during acute HCV infection are early prognostic factors of spontaneous clearance 69
Antibody Response To Respiratory Syncytial Virus Infection In Children <18 Months Old 69
Role of scavenger receptor class B type I in hepatitis C virus entry: kinetics and molecular determinants. 68
Cell entry of hepatitis C virus requires a set of co-receptors that include the CD81 tetraspanin and the SR-B1 scavenger receptor 68
2 Different Liver-specific Factors Stimulate Invitro Transcription From the Human Alpha-1-antitrypsin Promoter 68
Phase Ia clinical evaluation of the safety and immunogenicity of the Plasmodium falciparum blood-stage antigen AMA1 in ChAd63 and MVA vaccine vectors. 68
Novel human SR-BI antibodies prevent infection and dissemination of HCV in vitro and in humanized mice. 68
Totale 9.632
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Categoria #
all - tutte 46.248
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 46.248
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022810 8 2 12 4 11 36 34 33 210 22 57 381
2022/20231.047 178 78 6 115 124 130 1 86 160 102 50 17
2023/2024591 32 81 74 29 31 62 9 57 9 34 130 43
2024/20253.668 234 233 22 18 40 264 294 212 470 435 1.125 321
2025/20266.809 804 476 531 527 1.119 327 860 439 1.056 420 233 17
Totale 13.650