Peptides displayed on phage, which mimic continuous and discontinuous epitopes, can be selected using purified antibodies or preparations of polyclonal serum. This review describes recent advances in this field, discusses the application of phage-display technology to the diagnosis of human diseases, and presents new ideas for the preparation of vaccines directed against specific epitopes on a pathogen.
Epitope discovery using peptide libraries displayed on phage / Cortese, R; Felici, F; Galfre, G; Luzzago, A; Monaci, P; Nicosia, Alfredo. - In: TRENDS IN BIOTECHNOLOGY. - ISSN 0167-7799. - STAMPA. - 12:(1994), pp. 262-267. [10.1016/0167-7799(94)90137-6]
Epitope discovery using peptide libraries displayed on phage.
NICOSIA, Alfredo
1994
Abstract
Peptides displayed on phage, which mimic continuous and discontinuous epitopes, can be selected using purified antibodies or preparations of polyclonal serum. This review describes recent advances in this field, discusses the application of phage-display technology to the diagnosis of human diseases, and presents new ideas for the preparation of vaccines directed against specific epitopes on a pathogen.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
