IRIS
PICCOLI, RENATA
 Distribuzione geografica
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Continente #
AS - Asia 3.348
NA - Nord America 3.205
EU - Europa 3.085
SA - Sud America 499
AF - Africa 104
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 3
Totale 10.249
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Nazione #
US - Stati Uniti d'America 3.063
SG - Singapore 1.865
RU - Federazione Russa 1.464
CN - Cina 733
IT - Italia 540
BR - Brasile 412
HK - Hong Kong 289
VN - Vietnam 257
DE - Germania 214
FI - Finlandia 176
UA - Ucraina 161
IE - Irlanda 141
NL - Olanda 125
CA - Canada 80
GB - Regno Unito 70
IN - India 62
FR - Francia 49
SE - Svezia 44
ZA - Sudafrica 41
AR - Argentina 37
MX - Messico 36
PL - Polonia 35
CI - Costa d'Avorio 30
BD - Bangladesh 26
ES - Italia 20
JP - Giappone 20
TR - Turchia 15
EC - Ecuador 14
IQ - Iraq 11
CO - Colombia 10
ID - Indonesia 10
UZ - Uzbekistan 10
MA - Marocco 9
VE - Venezuela 8
IR - Iran 7
AE - Emirati Arabi Uniti 6
AT - Austria 6
IL - Israele 6
LT - Lituania 6
PK - Pakistan 6
PY - Paraguay 6
CH - Svizzera 5
CL - Cile 5
PA - Panama 5
HN - Honduras 4
KE - Kenya 4
LU - Lussemburgo 4
SA - Arabia Saudita 4
TN - Tunisia 4
AU - Australia 3
AZ - Azerbaigian 3
BE - Belgio 3
CR - Costa Rica 3
CZ - Repubblica Ceca 3
DK - Danimarca 3
EG - Egitto 3
EU - Europa 3
HU - Ungheria 3
JM - Giamaica 3
JO - Giordania 3
PT - Portogallo 3
AL - Albania 2
BG - Bulgaria 2
BH - Bahrain 2
BW - Botswana 2
BZ - Belize 2
DO - Repubblica Dominicana 2
GN - Guinea 2
LC - Santa Lucia 2
SY - Repubblica araba siriana 2
UY - Uruguay 2
AO - Angola 1
BB - Barbados 1
BJ - Benin 1
BO - Bolivia 1
BS - Bahamas 1
BY - Bielorussia 1
CG - Congo 1
EE - Estonia 1
ET - Etiopia 1
GF - Guiana Francese 1
GR - Grecia 1
GY - Guiana 1
HT - Haiti 1
KR - Corea 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
LK - Sri Lanka 1
MK - Macedonia 1
ML - Mali 1
MY - Malesia 1
NC - Nuova Caledonia 1
NG - Nigeria 1
NI - Nicaragua 1
NP - Nepal 1
NZ - Nuova Zelanda 1
PE - Perù 1
PH - Filippine 1
PS - Palestinian Territory 1
Totale 10.240
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Città #
Singapore 809
Chandler 417
Moscow 389
Hong Kong 288
Beijing 252
Ashburn 242
Jacksonville 146
Millbury 143
Princeton 126
Amsterdam 116
Los Angeles 103
Santa Clara 101
Naples 100
Napoli 97
Ho Chi Minh City 82
Nanjing 78
Munich 61
New York 56
Houston 53
Boston 52
Buffalo 48
San Jose 47
Wilmington 46
Ottawa 45
Dallas 43
São Paulo 41
Hanoi 40
The Dalles 35
Redondo Beach 34
Woodbridge 33
Seattle 32
Turku 32
Frankfurt am Main 27
Helsinki 27
Warsaw 27
Brooklyn 24
Dong Ket 24
Hefei 24
Shenyang 23
Norwalk 21
Tianjin 21
Treviso 21
Hyderabad 20
Nanchang 20
Düsseldorf 19
Cagliari 18
Kronberg 18
Mexico City 18
Tokyo 18
Chicago 17
Montreal 17
Orem 17
Rio de Janeiro 17
Stockholm 17
Hebei 16
Denver 15
Falls Church 15
Pune 15
San Francisco 15
Chennai 14
Falkenstein 14
Des Moines 13
Johannesburg 13
Phoenix 13
Dearborn 12
Haiphong 12
London 12
Orange 12
Rome 12
Atlanta 11
Poplar 11
Changsha 10
Guangzhou 10
Kunming 10
Belo Horizonte 9
Boardman 9
Curitiba 9
Da Nang 9
Jiaxing 9
Jinan 9
Tashkent 9
Biên Hòa 8
Caserta 8
Quito 8
Brasília 7
Cape Town 7
Manchester 7
Milan 7
Ningbo 7
Porto Alegre 7
Redwood City 7
Secaucus 7
Taizhou 7
Wroclaw 7
Aviano 6
Querétaro 6
Shanghai 6
Buenos Aires 5
Elk Grove Village 5
Hải Dương 5
Totale 5.087
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Nome #
Femtosecond UV-laser pulses to unveil protein-protein interactions in living cells 193
Novel human bioactive peptides identified in Apolipoprotein B: Evaluation of their therapeutic potential 192
Protein conformational perturbations in hereditary amyloidosis: Differential impact of single point mutations in ApoAI amyloidogenic variants 146
Malvidin and cyanidin derivatives from açai fruit (Euterpe oleracea Mart.) counteract UV-A-induced oxidative stress in immortalized fibroblasts 134
Identification of novel direct protein-protein interactions by irradiating living cells with femtosecond UV laser pulses 132
Enzymatically active fibrils generated by self-assembly of the ApoA-I fibrillogenic domain functionalized with a catalytic moiety. 127
Apolipoprotein A-I amyloidogenic variant L174S, expressed and isolated from stably transfected mammalian cells, is associated with fatty acids 126
Novel human antimicrobial peptides from ApoB are endowed with promising anti-inflammatory properties 125
Catalytic fibrils, a nanoscale biomaterial generated by amyloid fibrils functionalized with an enzyme 122
Biocompatibility, uptake and endocytosis pathways of polystyrene nanoparticles in primary human renal epithelial cells. 122
Insights into the interaction of the N-terminal amyloidogenic polypeptide of ApoA-I with model cellular membranes 121
Simultaneous production of antioxidants and starch from the microalga Chlorella sorokiniana 121
The 93-residue N-terminal domain of apolipoprotein A-I (ApoA-I), responsible for amyloid formation, is a cytotoxic agent. 119
Ribonucleasi Pancreatica e Seminale della Specie Bovina 117
The molecular basis for the production of an antitumor protein 116
Amyloidoses associated to Apolipoprotein A-I: analysis of the molecular bases of the disease 116
A proteomic approach to investigate the effects of cadmium and lead on human primary renal cells. 115
Immunotoxins and ImmunoRNases 109
Expression and characterization of recombinant apolipoprotein A-I (ApoA-I) fibrillogenic domain: first steps towards a structural and functional definition of ApoA-I associated amyloidosis 108
Transglutaminase-mediated crosslinking of a host defence peptide derived from human apolipoprotein B and its effect on the peptide antimicrobial activity 108
Effects of protein RNase inhibitor and substrate on the quaternary structures of bovine seminal RNase 107
Protective effect of Opuntia ficus-indica L. cladodes against UVA-induced oxidative stress in normal human keratinocytes 107
Thermodynamic stability of the two isoforms of bovine seminal ribonuclease. 106
Human Antitumor RNases and ImmunoRNases 104
A dimeric mutant of human pancreas ribonuclease with selective antitumor action 104
Expression of human apolipoprotein A-I in Nicotiana tabacum 103
Apolipoprotein A-I associated amyloidoses: the intriguing case of a natively unfolded protein fragment. 103
Recombinant amyloidogenic domain of ApoA-I: analysis of its fibrillogenic potential 102
Bioactive protein-based films containing an antimicrobial apolipoprotein B fragment. 102
The singular case of seminal RNase, a dimer with two quaternary conformations, inspected with Trypsin as a conformational probe 101
Nuclear and plastidial expression of the gene encoding human apolipoprotein ApoA.I in tobacco 101
Antitumor pancreatic-type RNases 101
Trypsin sheds light on the singular case of seminal RNase, a dimer with two quaternary conformations. 100
Antineoplastic ribonucleases selectively kill thyroid carcinoma cells via caspase-mediated induction of apoptosis 100
Expression of ApoA-I human apolipoprotein mutants in tobacco plants 100
Insights into the fate of the N-terminal amyloidogenic polypeptide of ApoA-I in cultured target cells. 100
Amyloidogenic variant of apolipoprotein A-I elicits cellular stress by attenuating the protective activity of angiogenin 100
Cell milieu significantly affects the fate of AApoAI amyloidogenic variants: predestination or serendipity? 100
A new human antitumor immunoreagent specific for ErbB2 99
Second generation human antitumour RNase. Significance of its structural and functional features for the mechanism of antitumour action. 99
Highly selective toxic and proapoptotic effects of two dimeric ribonucleases on thyroid cancer cells compared to the effects of doxorubicin 97
Effects of a lipid environment on the fibrillogenic pathway of the N-terminal polypeptide of human apolipoprotein A-I, responsible for in vivo amyloid fibril formation 97
Antioxidant and hypolipidemic activity of açai fruit makes it a valuable functional food 97
Effects of iron on the aggregation propensity of the N-terminal fibrillogenic polypeptide of human apolipoprotein A-I 96
IMMUNORNASES AS ANTITUMOUR AGENTS 95
Amyloidoses associated to apolipoprotein A-I: The intriguing case of a natively unfolded protein fragment 95
Binding, internalization and extracellular route of the fibrillogenic fragment of ApoA-I in cardiomyoblasts 95
Bovine seminal ribonuclease, a problem protein 94
The antitumor action of seminal ribonuclease and its quaternary conformations 94
STRUCTURAL INVESTIGATION OF MONOMERIC AND DIMERIC FORMS OF BOVINE SEMINAL RIBONUCLEASE 93
Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variant 93
Bovine Seminal RNase: an atypical member of the ribonuclease superfamily 93
Human, Anti-ErbB2 Antitumor Immunoagents 92
Comparative proton NMR studies on bovine semen and pancreas ribonucleases. 91
A new RNase-based immunoconjugate selectively cytotoxic for ErbB2-overexpressing cells. 89
A fully human antitumor immunoRNase selective for ErbB-2-positive carcinomas. 89
Seminal RNAase and Other RISBASES 89
Fibrillogenesis of ApoA-1 1-93: Identification of an intermediate with a collapsed and partially folded conformation 88
BS-RNase tetramers: an example of domain swapped oligomers 88
Muteins of pancreatic ribonuclease and uses thereof 87
A new strategy for the early diagnosis of rheumatoid arthritis: a combined approach. 87
A human, compact, fully functional anti-ErbB2 antibody as a novel antitumour agent 86
Characterization of the angiogenic activity of zebrafish ribonucleases. 86
Effects of the known pathogenic mutations on the aggregation pathway of the amyloidogenic Peptide of apolipoprotein a-I. 85
Anticooperative Binding of Cytidine-2'-Phosphate to Ribonuclease BS-1 85
In vivo and in vitro growth-inhibitory effect of bovine seminal ribonuclease on a system of rat thyroid epithelial transformed cells and tumors. 84
Ribonucleases as Antitumor Agents 84
Human mini-antibody cytotoxic for tumor cells which express the ErbB2 receptor 83
Chimeric anti-angiogenin antibody cAb 26-2F inhibits the formation of human breast cancer xenografts in athymic mice 81
X-ray diffraction studies of two dimeric variants of human pancreatic ribonuclease 79
Key extracellular and intracellular steps in the antitumor action of seminal ribonuclease 79
Strategies for Protein Engineering of Ribonucleases with Farmacological Potentials 79
ImmunoRNases as antitumor agents 79
Seminal RNase: a Unique Member of the Ribonuclease Superfamily 77
Fully Human Anti-Cancer ImmunoAgents 77
In planta expression of a human apolipoprotein 76
A dimeric mutant of human pancreatic ribonuclease with selective cytotoxicity towards malignant cells 76
RNAases and RISBASES 76
Selective Deamidation of Ribonuclease A 76
Apolipoprotein A-I: the dual face of a protein 70
“Construction and characterization of a fully human antitumor immunoRNase selective for ErbB2-positive carcinomas” and “Analysis of the role of the membrane transporter ABCC2/MRP2 in multidrug resistance (MDR)” 69
Site-Directed Alkylation and Site-Site Interactions in Bovine Seminal Ribonuclease 68
Dimeric Organization and Functional Properties of Seminal Ribonuclease: their Relationships with the Structure and Function of Pancreatic RNase 68
Engineering of Seminal RNAase: First Steps Towards the Construction of Chimaeric Ribonucleases 68
Effects of disease-associated mutations on the aggregation process of the 93-residue N-terminal fragment of human apolipoprotein A-I 67
Selective and asymmetric action of trypsin on the dimeric forms of seminal RNase 66
Relazioni tra la Struttura Quaternaria della Ribonucleasi BS-1 e la Non Equivalenza Funzionale dei Siti Catalitici 65
Aggregation mechanisms of cystatins: a comparative study of monellin and orzacystatin. 64
Co-operativity in Seminal Ribonuclease Function: Kinetic Studies 64
A Gene Homologous to the Proenkephalin Gene is Expressed in a Tunicate (Ciona intestinalis). 64
Seminal ribonuclease: procedures for the preparation of natural and recombinant enzyme, of its quaternary isoforms, of monomeric forms; an assay for the selective cytotoxicity of the enzyme. 63
Expression of opioid genes in bovine seminal vescicles. 62
Production and characterization of recombinant fibrillogenic proteins and potential applications of protein self-assembly in nanobiotechnology 62
Crystal Structure of the Dimeric unswapped Form of Bovine Seminal Ribonuclease 61
Pathological and therapeutic antibodies: new tools for autoimmunity diagnosis and anticancer therapy 59
Reattività di-Metà-dei-Siti della Ribonucleasi BS-1 59
Deamidation and Ageing of Seminal Ribonuclease 59
Expression of Bovine Seminal Ribonuclease in Escherichia coli 59
Co-operativity in Seminal Ribonuclease Function: Binding Studies 58
Crystallization of multiple forms of bovine seminal ribonuclease in the liganded and unliganded state 57
Totale 9.327
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Categoria #
all - tutte 34.319
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 34.319
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021174 0 0 0 0 0 0 36 21 37 10 43 27
2021/2022726 5 1 3 6 10 20 7 29 165 58 141 281
2022/2023936 135 81 26 74 119 94 5 99 156 111 28 8
2023/2024553 21 104 63 27 24 51 30 87 3 11 89 43
2024/20253.157 152 128 13 36 79 100 377 180 218 371 1.231 272
2025/20263.613 676 350 547 604 1.156 222 58 0 0 0 0 0
Totale 10.394