IRIS
PICCOLI, RENATA
 Distribuzione geografica
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Continente #
AS - Asia 4.428
NA - Nord America 4.310
EU - Europa 3.305
SA - Sud America 544
AF - Africa 124
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 3
Totale 12.719
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Nazione #
US - Stati Uniti d'America 4.148
SG - Singapore 1.913
RU - Federazione Russa 1.464
VN - Vietnam 974
CN - Cina 791
IT - Italia 566
BR - Brasile 431
HK - Hong Kong 340
DE - Germania 234
FR - Francia 191
FI - Finlandia 178
UA - Ucraina 162
IE - Irlanda 145
NL - Olanda 129
CA - Canada 91
JP - Giappone 86
GB - Regno Unito 79
IN - India 79
SE - Svezia 48
AR - Argentina 46
ZA - Sudafrica 45
BD - Bangladesh 39
MX - Messico 36
PL - Polonia 35
CI - Costa d'Avorio 30
PH - Filippine 26
IQ - Iraq 23
ES - Italia 21
EC - Ecuador 19
TR - Turchia 18
TW - Taiwan 18
KR - Corea 16
PK - Pakistan 15
TH - Thailandia 14
CO - Colombia 12
ID - Indonesia 12
VE - Venezuela 12
MA - Marocco 10
UZ - Uzbekistan 10
AT - Austria 8
EG - Egitto 8
LT - Lituania 8
CL - Cile 7
IL - Israele 7
IR - Iran 7
AE - Emirati Arabi Uniti 6
CR - Costa Rica 6
PA - Panama 6
PY - Paraguay 6
TN - Tunisia 6
CH - Svizzera 5
JM - Giamaica 5
JO - Giordania 5
KE - Kenya 5
SA - Arabia Saudita 5
CZ - Repubblica Ceca 4
HN - Honduras 4
LU - Lussemburgo 4
MY - Malesia 4
SY - Repubblica araba siriana 4
UY - Uruguay 4
AU - Australia 3
AZ - Azerbaigian 3
BE - Belgio 3
BZ - Belize 3
DK - Danimarca 3
DO - Repubblica Dominicana 3
EU - Europa 3
HU - Ungheria 3
LB - Libano 3
NG - Nigeria 3
PT - Portogallo 3
AL - Albania 2
AO - Angola 2
BG - Bulgaria 2
BH - Bahrain 2
BW - Botswana 2
CG - Congo 2
DZ - Algeria 2
ET - Etiopia 2
GN - Guinea 2
GY - Guiana 2
LC - Santa Lucia 2
NP - Nepal 2
PE - Perù 2
PS - Palestinian Territory 2
BB - Barbados 1
BJ - Benin 1
BO - Bolivia 1
BS - Bahamas 1
BY - Bielorussia 1
EE - Estonia 1
GF - Guiana Francese 1
GR - Grecia 1
HT - Haiti 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
LK - Sri Lanka 1
LV - Lettonia 1
MD - Moldavia 1
Totale 12.705
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Città #
Singapore 846
San Jose 688
Chandler 417
Moscow 389
Hong Kong 323
Ashburn 314
Beijing 257
Ho Chi Minh City 255
Hanoi 214
Jacksonville 147
Millbury 143
Princeton 126
Amsterdam 118
The Dalles 116
Los Angeles 115
Lauterbourg 113
Naples 108
Santa Clara 106
Napoli 97
Nanjing 78
Tokyo 74
New York 66
Munich 61
Houston 57
Boston 52
Buffalo 52
Dallas 51
Wilmington 46
Ottawa 45
Frankfurt am Main 44
São Paulo 42
Da Nang 41
Haiphong 37
Redondo Beach 34
Woodbridge 33
Seattle 32
Turku 32
Brooklyn 30
Helsinki 28
Warsaw 27
Council Bluffs 26
Dong Ket 24
Hefei 24
Norwalk 23
Shenyang 23
Chicago 21
Tianjin 21
Treviso 21
Hyderabad 20
Nanchang 20
Orem 20
Düsseldorf 19
San Francisco 19
Cagliari 18
Chennai 18
Denver 18
Kronberg 18
Mexico City 18
Montreal 18
Rio de Janeiro 18
Stockholm 17
Hebei 16
Johannesburg 16
Atlanta 15
Biên Hòa 15
Falls Church 15
Hải Dương 15
Phoenix 15
Pune 15
Thái Nguyên 15
Falkenstein 14
London 14
Des Moines 13
Rome 13
Dearborn 12
Orange 12
Quito 12
Poplar 11
Belo Horizonte 10
Changsha 10
Guangzhou 10
Kunming 10
Baghdad 9
Boardman 9
Bắc Giang 9
Bắc Ninh 9
Can Tho 9
Curitiba 9
Jiaxing 9
Jinan 9
Milan 9
Tashkent 9
Cape Town 8
Caserta 8
Manchester 8
Ninh Bình 8
Redwood City 8
Brasília 7
Bến Tre 7
Dublin 7
Totale 6.707
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Nome #
Novel human bioactive peptides identified in Apolipoprotein B: Evaluation of their therapeutic potential 237
Femtosecond UV-laser pulses to unveil protein-protein interactions in living cells 231
Malvidin and cyanidin derivatives from açai fruit (Euterpe oleracea Mart.) counteract UV-A-induced oxidative stress in immortalized fibroblasts 226
Protein conformational perturbations in hereditary amyloidosis: Differential impact of single point mutations in ApoAI amyloidogenic variants 174
Identification of novel direct protein-protein interactions by irradiating living cells with femtosecond UV laser pulses 173
Apolipoprotein A-I amyloidogenic variant L174S, expressed and isolated from stably transfected mammalian cells, is associated with fatty acids 163
Insights into the interaction of the N-terminal amyloidogenic polypeptide of ApoA-I with model cellular membranes 154
Amyloidoses associated to Apolipoprotein A-I: analysis of the molecular bases of the disease 149
The 93-residue N-terminal domain of apolipoprotein A-I (ApoA-I), responsible for amyloid formation, is a cytotoxic agent. 148
Immunotoxins and ImmunoRNases 147
Catalytic fibrils, a nanoscale biomaterial generated by amyloid fibrils functionalized with an enzyme 147
Novel human antimicrobial peptides from ApoB are endowed with promising anti-inflammatory properties 146
Biocompatibility, uptake and endocytosis pathways of polystyrene nanoparticles in primary human renal epithelial cells. 145
Enzymatically active fibrils generated by self-assembly of the ApoA-I fibrillogenic domain functionalized with a catalytic moiety. 143
Simultaneous production of antioxidants and starch from the microalga Chlorella sorokiniana 143
Antitumor pancreatic-type RNases 141
Human Antitumor RNases and ImmunoRNases 136
Expression and characterization of recombinant apolipoprotein A-I (ApoA-I) fibrillogenic domain: first steps towards a structural and functional definition of ApoA-I associated amyloidosis 136
Effects of protein RNase inhibitor and substrate on the quaternary structures of bovine seminal RNase 134
Transglutaminase-mediated crosslinking of a host defence peptide derived from human apolipoprotein B and its effect on the peptide antimicrobial activity 134
The molecular basis for the production of an antitumor protein 133
Protective effect of Opuntia ficus-indica L. cladodes against UVA-induced oxidative stress in normal human keratinocytes 133
Ribonucleasi Pancreatica e Seminale della Specie Bovina 132
The singular case of seminal RNase, a dimer with two quaternary conformations, inspected with Trypsin as a conformational probe 130
Binding, internalization and extracellular route of the fibrillogenic fragment of ApoA-I in cardiomyoblasts 130
A proteomic approach to investigate the effects of cadmium and lead on human primary renal cells. 129
Thermodynamic stability of the two isoforms of bovine seminal ribonuclease. 128
The antitumor action of seminal ribonuclease and its quaternary conformations 128
A dimeric mutant of human pancreas ribonuclease with selective antitumor action 127
Bioactive protein-based films containing an antimicrobial apolipoprotein B fragment. 126
Amyloidogenic variant of apolipoprotein A-I elicits cellular stress by attenuating the protective activity of angiogenin 124
Expression of ApoA-I human apolipoprotein mutants in tobacco plants 123
Expression of human apolipoprotein A-I in Nicotiana tabacum 122
Cell milieu significantly affects the fate of AApoAI amyloidogenic variants: predestination or serendipity? 121
Trypsin sheds light on the singular case of seminal RNase, a dimer with two quaternary conformations. 120
Bovine Seminal RNase: an atypical member of the ribonuclease superfamily 120
Antioxidant and hypolipidemic activity of açai fruit makes it a valuable functional food 120
A new human antitumor immunoreagent specific for ErbB2 119
Second generation human antitumour RNase. Significance of its structural and functional features for the mechanism of antitumour action. 119
Recombinant amyloidogenic domain of ApoA-I: analysis of its fibrillogenic potential 119
Nuclear and plastidial expression of the gene encoding human apolipoprotein ApoA.I in tobacco 119
Amyloidoses associated to apolipoprotein A-I: The intriguing case of a natively unfolded protein fragment 119
Apolipoprotein A-I associated amyloidoses: the intriguing case of a natively unfolded protein fragment. 118
Highly selective toxic and proapoptotic effects of two dimeric ribonucleases on thyroid cancer cells compared to the effects of doxorubicin 117
IMMUNORNASES AS ANTITUMOUR AGENTS 117
Human, Anti-ErbB2 Antitumor Immunoagents 117
Antineoplastic ribonucleases selectively kill thyroid carcinoma cells via caspase-mediated induction of apoptosis 115
Insights into the fate of the N-terminal amyloidogenic polypeptide of ApoA-I in cultured target cells. 113
Effects of iron on the aggregation propensity of the N-terminal fibrillogenic polypeptide of human apolipoprotein A-I 113
Effects of a lipid environment on the fibrillogenic pathway of the N-terminal polypeptide of human apolipoprotein A-I, responsible for in vivo amyloid fibril formation 112
Seminal RNAase and Other RISBASES 112
STRUCTURAL INVESTIGATION OF MONOMERIC AND DIMERIC FORMS OF BOVINE SEMINAL RIBONUCLEASE 111
A human, compact, fully functional anti-ErbB2 antibody as a novel antitumour agent 110
Muteins of pancreatic ribonuclease and uses thereof 110
Bovine seminal ribonuclease, a problem protein 109
A new strategy for the early diagnosis of rheumatoid arthritis: a combined approach. 107
Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variant 107
Ribonucleases as Antitumor Agents 107
A new RNase-based immunoconjugate selectively cytotoxic for ErbB2-overexpressing cells. 106
In vivo and in vitro growth-inhibitory effect of bovine seminal ribonuclease on a system of rat thyroid epithelial transformed cells and tumors. 106
Fibrillogenesis of ApoA-1 1-93: Identification of an intermediate with a collapsed and partially folded conformation 106
BS-RNase tetramers: an example of domain swapped oligomers 106
A fully human antitumor immunoRNase selective for ErbB-2-positive carcinomas. 104
Comparative proton NMR studies on bovine semen and pancreas ribonucleases. 104
X-ray diffraction studies of two dimeric variants of human pancreatic ribonuclease 103
Key extracellular and intracellular steps in the antitumor action of seminal ribonuclease 103
Strategies for Protein Engineering of Ribonucleases with Farmacological Potentials 103
ImmunoRNases as antitumor agents 103
Characterization of the angiogenic activity of zebrafish ribonucleases. 101
Human mini-antibody cytotoxic for tumor cells which express the ErbB2 receptor 100
Selective Deamidation of Ribonuclease A 100
Chimeric anti-angiogenin antibody cAb 26-2F inhibits the formation of human breast cancer xenografts in athymic mice 97
RNAases and RISBASES 97
Anticooperative Binding of Cytidine-2'-Phosphate to Ribonuclease BS-1 97
Effects of the known pathogenic mutations on the aggregation pathway of the amyloidogenic Peptide of apolipoprotein a-I. 96
Site-Directed Alkylation and Site-Site Interactions in Bovine Seminal Ribonuclease 96
Seminal RNase: a Unique Member of the Ribonuclease Superfamily 92
Fully Human Anti-Cancer ImmunoAgents 89
Apolipoprotein A-I: the dual face of a protein 89
Selective and asymmetric action of trypsin on the dimeric forms of seminal RNase 88
Dimeric Organization and Functional Properties of Seminal Ribonuclease: their Relationships with the Structure and Function of Pancreatic RNase 88
In planta expression of a human apolipoprotein 87
A dimeric mutant of human pancreatic ribonuclease with selective cytotoxicity towards malignant cells 85
Effects of disease-associated mutations on the aggregation process of the 93-residue N-terminal fragment of human apolipoprotein A-I 85
“Construction and characterization of a fully human antitumor immunoRNase selective for ErbB2-positive carcinomas” and “Analysis of the role of the membrane transporter ABCC2/MRP2 in multidrug resistance (MDR)” 82
Expression of Bovine Seminal Ribonuclease in Escherichia coli 82
Engineering of Seminal RNAase: First Steps Towards the Construction of Chimaeric Ribonucleases 82
Co-operativity in Seminal Ribonuclease Function: Kinetic Studies 81
Relazioni tra la Struttura Quaternaria della Ribonucleasi BS-1 e la Non Equivalenza Funzionale dei Siti Catalitici 81
Production and characterization of recombinant fibrillogenic proteins and potential applications of protein self-assembly in nanobiotechnology 78
Aggregation mechanisms of cystatins: a comparative study of monellin and orzacystatin. 76
Seminal ribonuclease: procedures for the preparation of natural and recombinant enzyme, of its quaternary isoforms, of monomeric forms; an assay for the selective cytotoxicity of the enzyme. 75
A Gene Homologous to the Proenkephalin Gene is Expressed in a Tunicate (Ciona intestinalis). 74
La RNAasi BS-1 come Enzima Soggetto a Controllo : una Ipotesi di Lavoro 73
Deamidation and Ageing of Seminal Ribonuclease 72
Crystal Structure of the Dimeric unswapped Form of Bovine Seminal Ribonuclease 71
Seminal Ribonuclease: the importance of diversity 71
Pathological and therapeutic antibodies: new tools for autoimmunity diagnosis and anticancer therapy 71
L'ingegneria proteica applicata ad enzimi con proprietà biologiche di interesse biotecnologico: il caso delle ribonucleasi 71
Reattività di-Metà-dei-Siti della Ribonucleasi BS-1 71
Totale 11.485
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Categoria #
all - tutte 40.720
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 40.720
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022726 5 1 3 6 10 20 7 29 165 58 141 281
2022/2023936 135 81 26 74 119 94 5 99 156 111 28 8
2023/2024553 21 104 63 27 24 51 30 87 3 11 89 43
2024/20253.157 152 128 13 36 79 100 377 180 218 371 1.231 272
2025/20266.039 676 350 547 604 1.156 222 858 354 671 453 80 68
2026/202744 44 0 0 0 0 0 0 0 0 0 0 0
Totale 12.864