IRIS
D'ALESSIO, GIUSEPPE
 Distribuzione geografica
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Continente #
NA - Nord America 5.643
AS - Asia 5.329
EU - Europa 3.770
SA - Sud America 666
Continente sconosciuto - Info sul continente non disponibili 166
AF - Africa 133
OC - Oceania 6
Totale 15.713
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Nazione #
US - Stati Uniti d'America 5.399
SG - Singapore 2.401
RU - Federazione Russa 1.696
VN - Vietnam 1.082
CN - Cina 916
BR - Brasile 517
IT - Italia 470
HK - Hong Kong 396
UA - Ucraina 286
DE - Germania 244
FR - Francia 226
FI - Finlandia 208
IE - Irlanda 196
CA - Canada 141
NL - Olanda 122
JP - Giappone 120
SE - Svezia 108
GB - Regno Unito 105
IN - India 88
BD - Bangladesh 56
AR - Argentina 55
MX - Messico 49
PL - Polonia 36
ZA - Sudafrica 36
PH - Filippine 31
CI - Costa d'Avorio 30
EC - Ecuador 27
TR - Turchia 27
IQ - Iraq 26
KR - Corea 25
TH - Thailandia 25
TW - Taiwan 25
CO - Colombia 22
ES - Italia 21
ID - Indonesia 20
PK - Pakistan 18
CL - Cile 11
VE - Venezuela 11
JM - Giamaica 10
UZ - Uzbekistan 10
DZ - Algeria 9
EG - Egitto 9
CR - Costa Rica 8
PY - Paraguay 8
SA - Arabia Saudita 8
AT - Austria 7
TN - Tunisia 7
EU - Europa 6
HN - Honduras 6
KE - Kenya 6
BE - Belgio 5
ET - Etiopia 5
KZ - Kazakistan 5
MY - Malesia 5
PE - Perù 5
PS - Palestinian Territory 5
SN - Senegal 5
AE - Emirati Arabi Uniti 4
AL - Albania 4
AO - Angola 4
BZ - Belize 4
DO - Repubblica Dominicana 4
JO - Giordania 4
LB - Libano 4
LT - Lituania 4
MA - Marocco 4
MD - Moldavia 4
NI - Nicaragua 4
TT - Trinidad e Tobago 4
UY - Uruguay 4
AU - Australia 3
AZ - Azerbaigian 3
BH - Bahrain 3
BO - Bolivia 3
EE - Estonia 3
IR - Iran 3
KG - Kirghizistan 3
LU - Lussemburgo 3
LV - Lettonia 3
NG - Nigeria 3
OM - Oman 3
PA - Panama 3
SY - Repubblica araba siriana 3
BF - Burkina Faso 2
BY - Bielorussia 2
CH - Svizzera 2
DK - Danimarca 2
GT - Guatemala 2
HT - Haiti 2
HU - Ungheria 2
LY - Libia 2
MK - Macedonia 2
NP - Nepal 2
PG - Papua Nuova Guinea 2
PT - Portogallo 2
RO - Romania 2
YT - Mayotte 2
AM - Armenia 1
BB - Barbados 1
BJ - Benin 1
Totale 15.523
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Città #
Singapore 1.021
San Jose 725
Chandler 597
Moscow 431
Hong Kong 384
Ashburn 338
Ho Chi Minh City 312
Jacksonville 277
Beijing 270
Hanoi 236
Millbury 211
The Dalles 201
Princeton 167
Los Angeles 160
Santa Clara 159
Lauterbourg 151
Amsterdam 110
Naples 108
Tokyo 106
Council Bluffs 102
Buffalo 84
Ottawa 79
Nanjing 77
Wilmington 73
Boston 72
New York 72
Munich 57
Houston 53
Hefei 50
Phoenix 50
Redondo Beach 48
São Paulo 46
Da Nang 45
Napoli 43
Dallas 42
Woodbridge 39
Cagliari 37
Haiphong 36
Frankfurt am Main 33
Chicago 32
Seattle 31
Warsaw 30
Dearborn 29
Mexico City 27
Nanchang 27
Brooklyn 25
Denver 25
Kronberg 25
Shenyang 25
Orange 24
Ann Arbor 23
Falls Church 23
Changsha 22
Milan 22
Montreal 22
Norwalk 22
Orem 22
Rio de Janeiro 21
Tianjin 21
Boardman 20
Turku 20
Atlanta 19
Helsinki 19
San Francisco 19
Johannesburg 18
London 18
Poplar 18
Kunming 17
Stockholm 17
Pune 16
Chennai 15
Manchester 15
Rome 15
Treviso 15
Thái Nguyên 14
Belo Horizonte 13
Hải Dương 13
Quito 12
Ankara 11
Campinas 11
Düsseldorf 11
Hangzhou 11
Mumbai 11
Bangkok 10
Guangzhou 10
Jinan 10
Ninh Bình 10
Tashkent 10
Baghdad 9
Bắc Ninh 9
Can Tho 9
Jiaxing 9
Quận Ba 9
Curitiba 8
Fortaleza 8
Guarulhos 8
Salvador 8
Toronto 8
Washington 8
Bologna 7
Totale 8.118
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Nome #
PHYSICO-CHEMICAL CHARACTERZATION OF GEODIN: A NEW B, G- CRYSTALLINE- TYPE PROTEIN SPONGE 172
Ribonucleases and angiogenins from fish. 165
A new RNase sheds light on the RNase/angiogenin subfamily from zebrafish 161
CYTOSOLIC RNASE INHIBITOR ONLY AFFECTS RNASES WITH INTRINSIC CYTOTOXICITY. 156
3D domain swapping and protein aggregation 151
Immunotoxins and ImmunoRNases 150
Effects of a human compact anti-ErbB2 antibody on prostate cancer 149
Antitumor pancreatic-type RNases 142
Mechanisms of cardiotoxicity associated with ErbB2 inhibitors. 141
Interactions of the cytotoxic RNase A dimers with the cytosolic ribonuclease inhibitor 140
Human Antitumor RNases and ImmunoRNases 139
3D domain swapping and supramolecular assembly 138
Anti-ErbB2 human Immunoagents 137
ON THE THERMAL STABILITY OF THE TWO DIMERIC FORMS OF RIBONUCLEASE A. 136
Effects of protein RNase inhibitor and substrate on the quaternary structures of bovine seminal RNase 136
Comparison of preclinical cardiotoxic effects of different ErbB2 inhibitors. 136
The molecular basis for the production of an antitumor protein 136
Full antitumor action of recombinant seminal ribonuclease depends on the removal of its N-terminal methionine 136
Protein engineering of ribonucleases 134
Anti-ErbB2 Human Immunoagents 133
The antitumor action of seminal ribonuclease and its quaternary conformations 133
The singular case of seminal RNase, a dimer with two quaternary conformations, inspected with Trypsin as a conformational probe 132
A dimeric mutant of human pancreas ribonuclease with selective antitumor action 132
Ribonucleasi Pancreatica e Seminale della Specie Bovina 132
Ribonucleases with angiogenic and bactericidal activities from the Atlantic salmon 130
Anti-ErbB2 immunoagents 129
Intracellular route and mechanism of action of ERB-hRNase, a human anti-ErbB2 anticancer immunoagent. 127
Anti-ErbB2 human immunoagents 125
A Novel Human Anti-tumor Dimeric ImmunoRNase 124
A novel ErbB2 epitope targeted by human antitumor immunoagents 123
Bovine Seminal RNase: an atypical member of the ribonuclease superfamily 121
Human, Anti-ErbB2 Antitumor Immunoagents 120
Antineoplastic ribonucleases selectively kill thyroid carcinoma cells via caspase-mediated induction of apoptosis 119
The cytosolic ribonuclease inhibitor contributes to intracellular redox homeostasis 119
Highly selective toxic and proapoptotic effects of two dimeric ribonucleases on thyroid cancer cells compared to the effects of doxorubicin 119
IMMUNORNASES AS ANTITUMOUR AGENTS 119
1H and 15N sequential assignment and secondary structure of the monomeric N67D mutant of bovine seminal ribonuclease 118
A novel fully human antitumour immunoRNase targeting ErbB2-positive tumours. 118
Site-directed mutagenesis induces domain swapping and fibril formation in human pancreatic ribonuclease 117
Seminal RNAase and Other RISBASES 115
Cardiotoxic effects, or lack thereof, of anti-ErbB2 immunoagents 114
Differential binding of human immunoagents and Herceptin to the ErbB2 receptor 114
A new mutein of RNase A with enhanced antitumor action 113
A novel method for detection of seleno-methionine incorporation in protein crystals via Raman microscopy 112
A human, compact, fully functional anti-ErbB2 antibody as a novel antitumour agent 111
The swapping of terminal arms in ribonucleases: comparison of the solution structure of monomeric bovine seminal and pancreatic ribonucleases 110
Muteins of pancreatic ribonuclease and uses thereof 110
Bovine seminal ribonuclease, a problem protein 110
Binding of human immunoagents and Herceptin to the ErbB2 receptor 109
A new RNase-based immunoconjugate selectively cytotoxic for ErbB2-overexpressing cells. 108
Combinatorial experimental protocols for Erbicin-derived immunoagents and Herceptin 108
Domain swapping and protein fibril assembly 108
In vivo and in vitro growth-inhibitory effect of bovine seminal ribonuclease on a system of rat thyroid epithelial transformed cells and tumors. 108
NOVEL HUMAN ANTI-ErbB2 IMMUNOAGENTS 107
A fully human antitumor immunoRNase selective for ErbB-2-positive carcinomas. 106
Comparative proton NMR studies on bovine semen and pancreas ribonucleases. 106
Characterization of the angiogenic activity of zebrafish ribonucleases. 106
Key extracellular and intracellular steps in the antitumor action of seminal ribonuclease 106
Strategies for Protein Engineering of Ribonucleases with Farmacological Potentials 106
Investigating site-site interaction of BS-RNase by protein engineering 106
Seminal ribonuclease inhibits tumor growth and reduces the metastatic potential of Lewis lung carcinoma. 104
X-ray diffraction studies of two dimeric variants of human pancreatic ribonuclease 103
A NEW RNASE BASED IMMUNOCONJUGATE SELECTIVELY CYTOTOXIC FOR ERBB2-OVEREXPRESSING CELLS. 102
ESSENTIAL STATIONS IN THE INTRACELLULAR PATHWAYS OF CYTOTOXIC BOVINE SEMINAL RIBONUCLEASE 102
A role for the intersubunit disulfides of seminal RNase in the mechanism of its antitumor action. 102
A NEW HUMAN ANTITUMOR IMMUNOREAGENT SPECIFIC FOR ERBB2 101
Human mini-antibody cytotoxic for tumor cells which express the ErbB2 receptor 101
Selective Deamidation of Ribonuclease A 101
Bull Semen RNAase Revisited 100
The success of the RNase scaffold in the advance of biosciences and in evolution 99
RNAases and RISBASES 99
Anticooperative Binding of Cytidine-2'-Phosphate to Ribonuclease BS-1 99
Site-Directed Alkylation and Site-Site Interactions in Bovine Seminal Ribonuclease 98
IL MECCANISMO DATTIVITÀ ANTITUMORALE DELLA RIBONUCLEASI SEMINALE 97
DEGRADATION OF DOUBLE-STRANDED RNA BY HUMAN PANCREATIC RIBONUCLEASE: CRUCIAL ROLE OF NONCATALYTIC BASIC AMINO ACID RESIDUES. 97
Temporal and spatial expression of RNases from zebrafish (Danio rerio). 96
Un nuovo mutante della RNasi A dotato di attività antitumorale 96
1H AND 15N SEQUENTIAL ASSIGNEMENT AND SECONDARY STRUCTURE OF THE MONOMERIC N76D MUTANT OF BOVINE SEMINAL RIBONUCLEASE. 95
Thermodynamic stability of five RNases from zebrafish (Danio rerio) 95
A ROLE FOR THE INTERSUBUNIT DISULFIDES OF SEMINAL RNASE IN THE MECHANISM OF ITS ANTITUMOR ACTION. 94
A new RNase-based immunoconjugate selectively cytotoxic for ErbB2-overexpressing cells. 94
Ribonuclease A can be Transformed into a Dimeric Ribonuclease with Antitumor Activity 94
Seminal RNase: a Unique Member of the Ribonuclease Superfamily 94
Interactions of the cytotoxic RNase A dimers with the cytosolic ribonuclease inhibitor 92
A DIMERIC MUTANT OF HUMAN PANCREATIC RIBONUCLEASE WITH SELECTIVE CYTOTOXICITY TOWARD MALIGNANT CELLS 91
UN MODELLO SPERIMENTALE PER LO STUDIO DEL RUOLO DELLINIBITORE CITOSOLICO DELLE RIBONUCLEASI 90
Hints on the evolutionary design of a dimeric RNase with special bioactions 90
LA RIBONUCLEASI PANCREATICA UMANA: INTERAZIONI CON SUBSTRATI ED INIBITORI 89
The Determinants of the Dimeric Structure of Seminal Ribonuclease are Located in its N-Terminal Region 89
Dimeric Organization and Functional Properties of Seminal Ribonuclease: their Relationships with the Structure and Function of Pancreatic RNase 88
Expression of Bovine Seminal Ribonuclease in Escherichia coli 84
THE EVOLUTION OF MONOMERIC AND OLIGOMERIC BETAGAMMA-TYPE CRYSTALLINS. FACTS AND HYPOTHESES. 83
From immunotoxins to immunoRNases. 83
Cardiotoxic effects, or lack thereof, of anti-ErbB2 immunoagents 83
Protein Engineering of RNases of Biological Interest 83
Co-operativity in Seminal Ribonuclease Function: Kinetic Studies 83
Solution structure of the human pancreatic ribonuclease 83
Relazioni tra la Struttura Quaternaria della Ribonucleasi BS-1 e la Non Equivalenza Funzionale dei Siti Catalitici 82
Engineering of Seminal RNAase: First Steps Towards the Construction of Chimaeric Ribonucleases 82
Selective Deamidation and Enzymatic Methylation in Ribonucleases 81
Totale 11.257
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Categoria #
all - tutte 53.478
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 53.478
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022933 0 0 4 9 1 36 12 34 202 51 185 399
2022/20231.226 192 109 37 148 139 141 6 116 172 106 45 15
2023/2024657 29 121 81 44 26 46 13 99 3 13 132 50
2024/20253.667 211 194 26 15 108 141 448 206 218 410 1.360 330
2025/20267.122 777 449 682 640 1.387 287 834 465 909 489 102 101
2026/2027377 120 169 88 0 0 0 0 0 0 0 0 0
Totale 15.713