IRIS
RODRIQUEZ, MANUELA
 Distribuzione geografica
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Continente #
AS - Asia 2.227
EU - Europa 1.323
NA - Nord America 842
SA - Sud America 271
AF - Africa 34
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 2
Totale 4.705
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Nazione #
SG - Singapore 1.100
US - Stati Uniti d'America 789
CN - Cina 643
RU - Federazione Russa 611
IT - Italia 412
BR - Brasile 208
HK - Hong Kong 204
VN - Vietnam 127
KR - Corea 70
NL - Olanda 66
DE - Germania 50
FI - Finlandia 36
GB - Regno Unito 36
FR - Francia 28
CA - Canada 25
MX - Messico 22
AR - Argentina 20
IN - India 17
SE - Svezia 17
BD - Bangladesh 15
EC - Ecuador 15
UA - Ucraina 14
ZA - Sudafrica 14
IE - Irlanda 12
PL - Polonia 10
ES - Italia 9
JP - Giappone 8
CO - Colombia 6
ID - Indonesia 6
TR - Turchia 6
VE - Venezuela 6
CL - Cile 5
EG - Egitto 5
AL - Albania 4
AT - Austria 4
CI - Costa d'Avorio 4
MV - Maldive 4
PE - Perù 4
UY - Uruguay 4
UZ - Uzbekistan 4
BE - Belgio 3
IQ - Iraq 3
NZ - Nuova Zelanda 3
PY - Paraguay 3
TW - Taiwan 3
AE - Emirati Arabi Uniti 2
AU - Australia 2
CZ - Repubblica Ceca 2
DO - Repubblica Dominicana 2
GA - Gabon 2
GR - Grecia 2
HN - Honduras 2
IR - Iran 2
KZ - Kazakistan 2
RO - Romania 2
TH - Thailandia 2
TN - Tunisia 2
AZ - Azerbaigian 1
BF - Burkina Faso 1
BG - Bulgaria 1
BN - Brunei Darussalam 1
CH - Svizzera 1
CW - ???statistics.table.value.countryCode.CW??? 1
DK - Danimarca 1
DZ - Algeria 1
IL - Israele 1
JM - Giamaica 1
KE - Kenya 1
KH - Cambogia 1
KW - Kuwait 1
MA - Marocco 1
MT - Malta 1
MY - Malesia 1
NC - Nuova Caledonia 1
NP - Nepal 1
PA - Panama 1
PK - Pakistan 1
PT - Portogallo 1
RW - Ruanda 1
SA - Arabia Saudita 1
SO - Somalia 1
UG - Uganda 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 4.705
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Città #
Singapore 578
Hefei 366
Hong Kong 194
Moscow 147
Beijing 113
Ashburn 99
Santa Clara 69
Seoul 66
Naples 59
Los Angeles 53
Rome 52
Chandler 45
Ho Chi Minh City 43
Dallas 37
Hanoi 29
New York 25
Amsterdam 24
Milan 22
São Paulo 21
Buffalo 20
Redondo Beach 20
Napoli 19
Helsinki 16
Chicago 15
Millbury 14
Boston 13
Bologna 10
Falkenstein 10
Munich 10
Orem 10
Ottawa 10
Shenzhen 10
Atlanta 9
Brooklyn 9
Turin 9
Dearborn 8
Johannesburg 8
Mexico City 8
Rio de Janeiro 8
Seattle 8
The Dalles 8
Tokyo 7
Xi'an 7
Denver 6
Frankfurt am Main 6
Manchester 6
Nuremberg 6
Poplar 6
Princeton 6
Quito 6
Turku 6
Warsaw 6
Baronissi 5
Chennai 5
Des Moines 5
Dong Ket 5
Goiânia 5
Lappeenranta 5
Ninh Bình 5
Porto Alegre 5
San Jose 5
Stockholm 5
Toronto 5
Belo Horizonte 4
Biên Hòa 4
Council Bluffs 4
Da Nang 4
Fisciano 4
Haiphong 4
Jacksonville 4
Jinan 4
Kochi 4
Lawrence 4
London 4
Malé 4
Montevideo 4
Montreal 4
Nanjing 4
Orta di Atella 4
Phoenix 4
Rochdale 4
Tashkent 4
Acerra 3
Ankara 3
Asunción 3
Brasília 3
Buenos Aires 3
Dublin 3
Guayaquil 3
Hải Dương 3
Orvieto 3
Padua 3
Querétaro 3
Salvador 3
Santo André 3
Sarno 3
São José do Rio Preto 3
Thái Bình 3
Tianjin 3
Tirana 3
Totale 2.547
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Nome #
Sintesi di derivati SAHA-like utilizzati per indagare sulla selettività verso le diverse isoforme HDAC 275
Gentamicina: derivatizzazione molecolare per migliorare la maneggevolezza sintetica e la farmacocinetica 165
Benzodiazepine Scaffold as Drug-like Molecular Simplification of FR235222: A Chemical Tool for Exploring HDAC Inhibition 131
Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization 130
Specific Targeting Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. Design, Synthesis, and Biological Evaluation of Novel, Potent, and Broad Spectrum NNRTIs with Antiviral Activity 129
Investigating the Neuroprotective Effects of Turmeric Extract: Structural Interactions of β-Amyloid Peptide with Single Curcuminoids 118
Co‐Crystalline Phases of Syndiotactic Polystyrene with Azelaic Acid Molecules of Pharmaceutical Interest 110
Build/couple/pair strategy: From nonchiral molecules to unbiased scaffolds, a methodological approach for the optimization of microwave-assisted intra-molecular Diels-Alder reaction of furans 106
The isoprenoid derivative N6-benzyladenosine (CM223) exerts antitumor effect in glioma patient-derived primary cells through the mevalonate pathway 105
Synthesis of Heterocycles via Microwave-Assisted Cycloadditions and Cyclocondensations 96
NMR for screening and a biochemical assay: Identification of new FPPS inhibitors exerting anticancer activity 96
A New Approach to Supramolecular Structure Determination in Pharmaceutical Preparation of Self-Assembling Peptides: A Case Study of Lanreotide Autogel 94
Chemistry and biology of anti-inflammatory marine natural products: molecules interfering with cyclooxygenase, NF-κB and other unidentified targets 93
Peptides as modulators of FPPS enzyme: A multifaceted evaluation from the design to the mechanism of action 92
Cocoa Extract Provides Protection against 6-OHDA Toxicity in SH-SY5Y Dopaminergic Neurons by Targeting PERK 92
A Spironolactone-Based Prototype of an Innovative Biomedical Patch for Wound Dressing Applications 91
Identification of CM223 as a new ligand of farnesyl pyrophosphate synthase with improved antiglioma action 91
Ganoderma lucidum ethanol extracts enhance re-epithelialization and prevent keratinocytes from free-radical injury 91
Salicylic Acid Release from Syndiotactic Polystyrene Staple Fibers 87
A Structural Effect of the Antioxidant Curcuminoids on the Aβ(1–42) Amyloid Peptide 84
Structural analysis of a simplified model reproducing SARS-CoV-2 S RBD/ACE2 binding site 81
Is it time to integrate sex and gender into drug design and development? 80
Fabrication of Novel Bio-Composites Based on Rice Milk for the Delivery of Capsaicinoids as Green Herbicides against Cynodon dactylon Weed 80
1,3-Cycloaddition of nitrile oxides in ionic liquids. An easier route to 3-carboxy isoxazolines, potential constrained glutamic acid analogues 80
Total synthesis and biological evaluation of halipeptins A and D and analogues. 80
Towards an improvement of anticancer activity of benzyl adenosine analogs 80
Synthesis of enantiopure 7-substituted azepane-2-carboxylic acids as templates for conformationally constrained peptidomimetics 78
Histone deacetylase inhibitors in the treatment of cancer: overview and perspectives 78
Skeletally Diverse Small Molecules Using a Build/Couple/Pair Strategy 73
Saliva of patients affected by salivary gland tumour: An NMR metabolomics analysis 72
Oxime amides as a novel zinc binding group in histone deacetylase inhibitors: synthesis, biological activity, and computational evaluation 71
Epoxidation of 17-oxo-15,16-methylene steroids with sulfoxonium ylides 69
TRYPTOPHAN-BASED LINEAR DIPEPTIDES AND 1,4-DIKETOPIPERAZINES AS SIMPLIFIED SCAFFOLDS OF THE NATURAL CYCLOTETRAPEPTIDE FR235222 68
Ionic Liquid as a Suitable Phase for Multistep Parallel Synthesis of an Array of Isoxazolines 67
Synthesis, structural aspects and cytotoxicity of the natural cyclopeptides yunnanins A, C and phakellistatins 1, 10 62
Total synthesis, NMR solution structure, and binding model of the potent histone deacetylase inhibitor FR235222 62
Synthesis and application in SPPS of a stable amino acid isostere of palmitoyl cysteine 61
Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: Role of Annexin A1 60
Solid-phase synthesis of conformationally constrained peptidomimetics based on a 3,6-disubstituted-1,4-diazepan-2,5-dione core 59
Synthesis and biological evaluation of small Molecules derivatives of the natural Histone deacetylase inhibitor FR235222 57
Fast determination of underivatized gentamicin C components and impurities by LC-MS using a porous graphitic carbon stationary phase 57
Synthesis of 2-amino-8-oxodecanoic acids (Aodas) present in natural hystone deacetylase inhibitors 56
N-thioalkylcarbazoles derivatives as new anti-proliferative agents: synthesis, characterisation and molecular mechanism evaluation 55
A serum nuclear magnetic resonance-based metabolomic signature of antiphospholipid syndrome 54
LGP1, a histone deacetylase inhibitor analogue of FR235222, sensitizes promyelocytic leukaemia U937 cells to TRAIL-mediated apoptosis 53
Synthesis of kainoids via a highly stereoselective hydroformylation of kainic acid 53
Endoplasmic Reticulum Stress and Its Role in Metabolic Reprogramming of Cancer 52
Developing Molecular Diversity in the Construction of a Family of Bicyclic Isoxazolines Scaffolds: Control of Regio-and Diastereoselectivities 50
Total synthesis and structural elucidation of azaspiracid-1. Construction of key building blocks for originally proposed structure 49
Histone deacetylase inhibitors in the treatment of hematological malignancies 48
A simple procedure for the transformation of L-glutamic acid into the corresponding γ-aldehyde 47
Histone deacetylase inhibitor FR235222 sensitizes human prostate adenocarcinoma cells to apoptosis through up-regulation of Annexin A1 46
Colorimetric tools for solid-phase organic synthesis 46
Downregulation of hypoxia-related responses by novel antitumor histone deacetylase inhibitors in MDAMB231 breast cancer cells 46
Chemistry and biology of chromatin remodeling agents: State of art and future perspectives of HDAC inhibitors 43
Design and synthesis of cyclopeptide analogues of the potent histone deacetylase inhibitor FR235222 42
Microwaves enhance cyclisation of tetrapeptides 40
Targeting STAT3 in cancer inhibition 37
?-Amyloid-acetylcholine molecular interaction: New role of cholinergic mediators in anti-Alzheimer therapy? 35
Transformation of glutamic acid into (S)-benzyl 2-(dibenzylamino)-6- (dimethoxyphosphoryl)-5-oxohexanoate for a convenient access to 5-substituted prolines 34
Facile Baeyer–Villiger oxidation of cyclic ketones: conventional versus microwave-assisted approach 30
Molecular modeling studies toward the structural optimization of new cyclopeptide-based HDAC inhibitors modeled on the natural product FR235222 29
Sensible Improvements Induced by Ionic Liquids in the Reaction of Modified Carbasugars with Bases for the Building of Constrained Carbanucleosides 29
Steroidal hydroxamic acid derivatives: A structurally novel class of HDAC inhibitors 29
Structural features of peptides derived from feline immunodeficiency virus TM-Glycoprotein 28
Synthesis and biological evaluation of Santacruzamate-A based analogues 26
Totale 4.808
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Categoria #
all - tutte 13.833
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 13.833
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202144 0 0 0 0 0 8 4 5 14 1 7 5
2021/202262 2 0 0 2 2 1 3 4 9 5 8 26
2022/2023149 10 10 1 11 18 25 12 11 16 17 9 9
2023/2024252 7 16 36 16 15 11 15 14 14 6 30 72
2024/20251.821 131 141 31 43 35 69 212 158 77 171 575 178
2025/20262.389 386 513 471 426 494 99 0 0 0 0 0 0
Totale 4.808