RODRIQUEZ, MANUELA
 Distribuzione geografica
Continente #
EU - Europa 496
AS - Asia 394
NA - Nord America 373
SA - Sud America 10
AF - Africa 4
OC - Oceania 2
Totale 1.279
Nazione #
US - Stati Uniti d'America 360
IT - Italia 310
SG - Singapore 197
HK - Hong Kong 138
RU - Federazione Russa 56
CN - Cina 42
NL - Olanda 32
FI - Finlandia 24
DE - Germania 22
CA - Canada 13
IE - Irlanda 11
SE - Svezia 10
FR - Francia 7
UA - Ucraina 7
BR - Brasile 6
GB - Regno Unito 6
VN - Vietnam 6
CI - Costa d'Avorio 4
EC - Ecuador 4
MV - Maldive 4
BE - Belgio 3
AT - Austria 2
BD - Bangladesh 2
CZ - Repubblica Ceca 2
NZ - Nuova Zelanda 2
CH - Svizzera 1
DK - Danimarca 1
ES - Italia 1
IN - India 1
IR - Iran 1
JP - Giappone 1
KZ - Kazakistan 1
RO - Romania 1
TR - Turchia 1
Totale 1.279
Città #
Hong Kong 136
Singapore 135
Santa Clara 59
Chandler 45
Rome 44
Naples 41
Ashburn 23
Napoli 19
Milan 18
Helsinki 16
Amsterdam 15
Millbury 14
Falkenstein 10
Ottawa 10
Bologna 9
Dallas 8
Dearborn 8
Shenzhen 8
Turin 8
Seattle 7
Princeton 6
Xi'an 6
Baronissi 5
Des Moines 5
Dong Ket 5
Boston 4
Goiânia 4
Jacksonville 4
Lawrence 4
Malé 4
Nanjing 4
Quito 4
Acerra 3
Dublin 3
New York 3
Orvieto 3
Sarno 3
Uccle 3
Auckland 2
Bitonto 2
Bollate 2
Buffalo 2
Casalmaiocco 2
Cerignola 2
Cesano Maderno 2
Council Bluffs 2
Espoo 2
Ferrara 2
Fisciano 2
Guangzhou 2
Görwihl 2
Hebei 2
Kronberg 2
Madrigale 2
Novara 2
Nuremberg 2
Parma 2
Pompiano 2
Portici 2
Pozzuoli 2
Salerno 2
San Giovanni al Natisone 2
San Mateo 2
Santa Maria di Sala 2
Siena 2
Tianjin 2
Toronto 2
Traversetolo 2
Trecate 2
Varedo 2
Venice 2
Abidjan 1
Agrate Conturbia 1
Barcelona 1
Boardman 1
Brno 1
Campo Magro 1
Cesa 1
Changchun 1
Changsha 1
Chicago 1
Chieti 1
Chongqing 1
College Station 1
Fermo 1
Ferrara di Monte Baldo 1
Frankfurt am Main 1
Hangzhou 1
Hefei 1
Ituiutaba 1
Jiaxing 1
Jinan 1
Karaganda 1
Leawood 1
London 1
Los Angeles 1
Manassas 1
Mercato San Severino 1
Middlesbrough 1
Nanchang 1
Totale 801
Nome #
Sintesi di derivati SAHA-like utilizzati per indagare sulla selettività verso le diverse isoforme HDAC 172
Gentamicina: derivatizzazione molecolare per migliorare la maneggevolezza sintetica e la farmacocinetica 76
Benzodiazepine Scaffold as Drug-like Molecular Simplification of FR235222: A Chemical Tool for Exploring HDAC Inhibition 74
Specific Targeting Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. Design, Synthesis, and Biological Evaluation of Novel, Potent, and Broad Spectrum NNRTIs with Antiviral Activity 66
Investigating the Neuroprotective Effects of Turmeric Extract: Structural Interactions of β-Amyloid Peptide with Single Curcuminoids 64
Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization 51
The isoprenoid derivative N6-benzyladenosine (CM223) exerts antitumor effect in glioma patient-derived primary cells through the mevalonate pathway 48
Ganoderma lucidum ethanol extracts enhance re-epithelialization and prevent keratinocytes from free-radical injury 37
Identification of CM223 as a new ligand of farnesyl pyrophosphate synthase with improved antiglioma action 36
NMR for screening and a biochemical assay: Identification of new FPPS inhibitors exerting anticancer activity 36
Oxime amides as a novel zinc binding group in histone deacetylase inhibitors: synthesis, biological activity, and computational evaluation 31
Total synthesis and biological evaluation of halipeptins A and D and analogues. 28
Histone deacetylase inhibitors in the treatment of cancer: overview and perspectives 27
Co‐Crystalline Phases of Syndiotactic Polystyrene with Azelaic Acid Molecules of Pharmaceutical Interest 26
Cocoa Extract Provides Protection against 6-OHDA Toxicity in SH-SY5Y Dopaminergic Neurons by Targeting PERK 26
Epoxidation of 17-oxo-15,16-methylene steroids with sulfoxonium ylides 24
Synthesis of Heterocycles via Microwave-Assisted Cycloadditions and Cyclocondensations 23
A Spironolactone-Based Prototype of an Innovative Biomedical Patch for Wound Dressing Applications 21
Towards an improvement of anticancer activity of benzyl adenosine analogs 21
Build/couple/pair strategy: From nonchiral molecules to unbiased scaffolds, a methodological approach for the optimization of microwave-assisted intra-molecular Diels-Alder reaction of furans 20
Salicylic Acid Release from Syndiotactic Polystyrene Staple Fibers 19
Fabrication of Novel Bio-Composites Based on Rice Milk for the Delivery of Capsaicinoids as Green Herbicides against Cynodon dactylon Weed 18
Facile Baeyer–Villiger oxidation of cyclic ketones: conventional versus microwave-assisted approach 18
Is it time to integrate sex and gender into drug design and development? 16
N-thioalkylcarbazoles derivatives as new anti-proliferative agents: synthesis, characterisation and molecular mechanism evaluation 16
1,3-Cycloaddition of nitrile oxides in ionic liquids. An easier route to 3-carboxy isoxazolines, potential constrained glutamic acid analogues 16
Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: Role of Annexin A1 15
Peptides as modulators of FPPS enzyme: A multifaceted evaluation from the design to the mechanism of action 15
A serum nuclear magnetic resonance-based metabolomic signature of antiphospholipid syndrome 15
Chemistry and biology of anti-inflammatory marine natural products: molecules interfering with cyclooxygenase, NF-κB and other unidentified targets 15
Synthesis and application in SPPS of a stable amino acid isostere of palmitoyl cysteine 14
A New Approach to Supramolecular Structure Determination in Pharmaceutical Preparation of Self-Assembling Peptides: A Case Study of Lanreotide Autogel 14
Skeletally Diverse Small Molecules Using a Build/Couple/Pair Strategy 14
Fast determination of underivatized gentamicin C components and impurities by LC-MS using a porous graphitic carbon stationary phase 14
Synthesis, structural aspects and cytotoxicity of the natural cyclopeptides yunnanins A, C and phakellistatins 1, 10 12
Synthesis of enantiopure 7-substituted azepane-2-carboxylic acids as templates for conformationally constrained peptidomimetics 12
TRYPTOPHAN-BASED LINEAR DIPEPTIDES AND 1,4-DIKETOPIPERAZINES AS SIMPLIFIED SCAFFOLDS OF THE NATURAL CYCLOTETRAPEPTIDE FR235222 12
Synthesis of kainoids via a highly stereoselective hydroformylation of kainic acid 12
Synthesis and biological evaluation of small Molecules derivatives of the natural Histone deacetylase inhibitor FR235222 11
LGP1, a histone deacetylase inhibitor analogue of FR235222, sensitizes promyelocytic leukaemia U937 cells to TRAIL-mediated apoptosis 11
Chemistry and biology of chromatin remodeling agents: State of art and future perspectives of HDAC inhibitors 11
Structural analysis of a simplified model reproducing SARS-CoV-2 S RBD/ACE2 binding site 10
Synthesis and biological evaluation of Santacruzamate-A based analogues 9
Downregulation of hypoxia-related responses by novel antitumor histone deacetylase inhibitors in MDAMB231 breast cancer cells 9
Steroidal hydroxamic acid derivatives: A structurally novel class of HDAC inhibitors 9
Ionic Liquid as a Suitable Phase for Multistep Parallel Synthesis of an Array of Isoxazolines 8
Solid-phase synthesis of conformationally constrained peptidomimetics based on a 3,6-disubstituted-1,4-diazepan-2,5-dione core 8
Total synthesis and structural elucidation of azaspiracid-1. Construction of key building blocks for originally proposed structure 8
Colorimetric tools for solid-phase organic synthesis 8
Histone deacetylase inhibitors in the treatment of hematological malignancies 8
Saliva of patients affected by salivary gland tumour: An NMR metabolomics analysis 8
Design and synthesis of cyclopeptide analogues of the potent histone deacetylase inhibitor FR235222 8
Molecular modeling studies toward the structural optimization of new cyclopeptide-based HDAC inhibitors modeled on the natural product FR235222 8
Transformation of glutamic acid into (S)-benzyl 2-(dibenzylamino)-6- (dimethoxyphosphoryl)-5-oxohexanoate for a convenient access to 5-substituted prolines 8
Histone deacetylase inhibitor FR235222 sensitizes human prostate adenocarcinoma cells to apoptosis through up-regulation of Annexin A1 7
A Structural Effect of the Antioxidant Curcuminoids on the Aβ(1–42) Amyloid Peptide 7
A simple procedure for the transformation of L-glutamic acid into the corresponding γ-aldehyde 7
Developing Molecular Diversity in the Construction of a Family of Bicyclic Isoxazolines Scaffolds: Control of Regio-and Diastereoselectivities 7
Synthesis of 2-amino-8-oxodecanoic acids (Aodas) present in natural hystone deacetylase inhibitors 6
Targeting STAT3 in cancer inhibition 6
Structural features of peptides derived from feline immunodeficiency virus TM-Glycoprotein 6
Total synthesis, NMR solution structure, and binding model of the potent histone deacetylase inhibitor FR235222 5
Microwaves enhance cyclisation of tetrapeptides 5
?-Amyloid-acetylcholine molecular interaction: New role of cholinergic mediators in anti-Alzheimer therapy? 5
Sensible Improvements Induced by Ionic Liquids in the Reaction of Modified Carbasugars with Bases for the Building of Constrained Carbanucleosides 4
Totale 1.381
Categoria #
all - tutte 6.671
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 6.671


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202011 0 0 0 0 0 0 0 1 1 0 2 7
2020/202153 1 1 5 1 1 8 4 5 14 1 7 5
2021/202262 2 0 0 2 2 1 3 4 9 5 8 26
2022/2023149 10 10 1 11 18 25 12 11 16 17 9 9
2023/2024252 7 16 36 16 15 11 15 14 14 6 30 72
2024/2025783 131 141 31 43 35 69 212 121 0 0 0 0
Totale 1.381