IRIS
RODRIQUEZ, MANUELA
 Distribuzione geografica
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Continente #
AS - Asia 2.666
EU - Europa 1.449
NA - Nord America 1.291
SA - Sud America 283
AF - Africa 42
OC - Oceania 7
Continente sconosciuto - Info sul continente non disponibili 2
Totale 5.740
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Nazione #
US - Stati Uniti d'America 1.233
SG - Singapore 1.153
CN - Cina 702
RU - Federazione Russa 612
IT - Italia 465
VN - Vietnam 300
HK - Hong Kong 217
BR - Brasile 210
FR - Francia 82
KR - Corea 75
NL - Olanda 70
JP - Giappone 66
DE - Germania 52
BD - Bangladesh 38
FI - Finlandia 37
GB - Regno Unito 37
CA - Canada 29
IN - India 29
MX - Messico 23
AR - Argentina 22
EC - Ecuador 18
SE - Svezia 17
ZA - Sudafrica 17
UA - Ucraina 15
IE - Irlanda 13
ES - Italia 12
IQ - Iraq 11
PH - Filippine 10
PL - Polonia 10
TH - Thailandia 10
ID - Indonesia 8
TR - Turchia 8
EG - Egitto 7
VE - Venezuela 7
CL - Cile 6
CO - Colombia 6
AT - Austria 5
PK - Pakistan 5
TW - Taiwan 5
AL - Albania 4
CH - Svizzera 4
CI - Costa d'Avorio 4
MV - Maldive 4
NZ - Nuova Zelanda 4
PE - Perù 4
PY - Paraguay 4
UY - Uruguay 4
UZ - Uzbekistan 4
AE - Emirati Arabi Uniti 3
BE - Belgio 3
MA - Marocco 3
SA - Arabia Saudita 3
TN - Tunisia 3
AU - Australia 2
AZ - Azerbaigian 2
BO - Bolivia 2
CZ - Repubblica Ceca 2
DO - Repubblica Dominicana 2
GA - Gabon 2
GR - Grecia 2
HN - Honduras 2
IL - Israele 2
IR - Iran 2
KZ - Kazakistan 2
MY - Malesia 2
RO - Romania 2
BF - Burkina Faso 1
BG - Bulgaria 1
BN - Brunei Darussalam 1
CW - ???statistics.table.value.countryCode.CW??? 1
DK - Danimarca 1
DZ - Algeria 1
JM - Giamaica 1
JO - Giordania 1
KE - Kenya 1
KH - Cambogia 1
KW - Kuwait 1
MT - Malta 1
NC - Nuova Caledonia 1
NO - Norvegia 1
NP - Nepal 1
PA - Panama 1
PT - Portogallo 1
RW - Ruanda 1
SO - Somalia 1
UG - Uganda 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 5.740
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Città #
Singapore 601
Hefei 366
San Jose 251
Hong Kong 201
Moscow 147
Ashburn 137
Beijing 121
Ho Chi Minh City 85
Santa Clara 70
Hanoi 69
Seoul 67
Naples 64
Los Angeles 60
Tokyo 60
Rome 58
The Dalles 55
Lauterbourg 52
Chandler 45
Dallas 45
New York 32
Amsterdam 24
Milan 24
São Paulo 21
Buffalo 20
Redondo Beach 20
Napoli 19
Helsinki 17
Chicago 16
Council Bluffs 14
Millbury 14
Boston 13
Da Nang 13
Orem 13
Turin 12
Bologna 11
Brooklyn 11
Shenzhen 11
Atlanta 10
Falkenstein 10
Johannesburg 10
Munich 10
Ottawa 10
Mexico City 9
Chennai 8
Dearborn 8
Denver 8
Haiphong 8
Rio de Janeiro 8
Seattle 8
Frankfurt am Main 7
Phoenix 7
Xi'an 7
Fisciano 6
Manchester 6
Ninh Bình 6
Nuremberg 6
Poplar 6
Princeton 6
Quito 6
Thái Bình 6
Toronto 6
Turku 6
Warsaw 6
Baronissi 5
Biên Hòa 5
Can Tho 5
Des Moines 5
Dong Ket 5
Goiânia 5
Lappeenranta 5
Porto Alegre 5
Stockholm 5
Bangkok 4
Belo Horizonte 4
Cairo 4
Dublin 4
Guayaquil 4
Houston 4
Hải Dương 4
Jacksonville 4
Jinan 4
Kochi 4
Lawrence 4
London 4
Malé 4
Montevideo 4
Montreal 4
Nanjing 4
Orta di Atella 4
Rochdale 4
Tashkent 4
Zurich 4
Abu Dhabi 3
Acerra 3
Ankara 3
Asunción 3
Auckland 3
Baghdad 3
Brasília 3
Buenos Aires 3
Totale 3.202
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Nome #
Sintesi di derivati SAHA-like utilizzati per indagare sulla selettività verso le diverse isoforme HDAC 323
Gentamicina: derivatizzazione molecolare per migliorare la maneggevolezza sintetica e la farmacocinetica 212
Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization 151
Benzodiazepine Scaffold as Drug-like Molecular Simplification of FR235222: A Chemical Tool for Exploring HDAC Inhibition 147
Specific Targeting Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. Design, Synthesis, and Biological Evaluation of Novel, Potent, and Broad Spectrum NNRTIs with Antiviral Activity 146
Co‐Crystalline Phases of Syndiotactic Polystyrene with Azelaic Acid Molecules of Pharmaceutical Interest 143
Investigating the Neuroprotective Effects of Turmeric Extract: Structural Interactions of β-Amyloid Peptide with Single Curcuminoids 140
The isoprenoid derivative N6-benzyladenosine (CM223) exerts antitumor effect in glioma patient-derived primary cells through the mevalonate pathway 124
Build/couple/pair strategy: From nonchiral molecules to unbiased scaffolds, a methodological approach for the optimization of microwave-assisted intra-molecular Diels-Alder reaction of furans 119
Chemistry and biology of anti-inflammatory marine natural products: molecules interfering with cyclooxygenase, NF-κB and other unidentified targets 119
NMR for screening and a biochemical assay: Identification of new FPPS inhibitors exerting anticancer activity 118
Peptides as modulators of FPPS enzyme: A multifaceted evaluation from the design to the mechanism of action 116
Ganoderma lucidum ethanol extracts enhance re-epithelialization and prevent keratinocytes from free-radical injury 116
A Spironolactone-Based Prototype of an Innovative Biomedical Patch for Wound Dressing Applications 115
Total synthesis and biological evaluation of halipeptins A and D and analogues. 113
Identification of CM223 as a new ligand of farnesyl pyrophosphate synthase with improved antiglioma action 112
Synthesis of Heterocycles via Microwave-Assisted Cycloadditions and Cyclocondensations 110
A New Approach to Supramolecular Structure Determination in Pharmaceutical Preparation of Self-Assembling Peptides: A Case Study of Lanreotide Autogel 110
Is it time to integrate sex and gender into drug design and development? 110
Salicylic Acid Release from Syndiotactic Polystyrene Staple Fibers 108
Cocoa Extract Provides Protection against 6-OHDA Toxicity in SH-SY5Y Dopaminergic Neurons by Targeting PERK 108
A Structural Effect of the Antioxidant Curcuminoids on the Aβ(1–42) Amyloid Peptide 103
Structural analysis of a simplified model reproducing SARS-CoV-2 S RBD/ACE2 binding site 96
Towards an improvement of anticancer activity of benzyl adenosine analogs 96
1,3-Cycloaddition of nitrile oxides in ionic liquids. An easier route to 3-carboxy isoxazolines, potential constrained glutamic acid analogues 93
Fabrication of Novel Bio-Composites Based on Rice Milk for the Delivery of Capsaicinoids as Green Herbicides against Cynodon dactylon Weed 91
Histone deacetylase inhibitors in the treatment of cancer: overview and perspectives 90
Oxime amides as a novel zinc binding group in histone deacetylase inhibitors: synthesis, biological activity, and computational evaluation 87
TRYPTOPHAN-BASED LINEAR DIPEPTIDES AND 1,4-DIKETOPIPERAZINES AS SIMPLIFIED SCAFFOLDS OF THE NATURAL CYCLOTETRAPEPTIDE FR235222 86
Skeletally Diverse Small Molecules Using a Build/Couple/Pair Strategy 85
Synthesis of enantiopure 7-substituted azepane-2-carboxylic acids as templates for conformationally constrained peptidomimetics 83
Saliva of patients affected by salivary gland tumour: An NMR metabolomics analysis 81
Epoxidation of 17-oxo-15,16-methylene steroids with sulfoxonium ylides 78
LGP1, a histone deacetylase inhibitor analogue of FR235222, sensitizes promyelocytic leukaemia U937 cells to TRAIL-mediated apoptosis 77
Endoplasmic Reticulum Stress and Its Role in Metabolic Reprogramming of Cancer 76
Ionic Liquid as a Suitable Phase for Multistep Parallel Synthesis of an Array of Isoxazolines 75
Total synthesis, NMR solution structure, and binding model of the potent histone deacetylase inhibitor FR235222 75
Synthesis and application in SPPS of a stable amino acid isostere of palmitoyl cysteine 70
Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: Role of Annexin A1 69
Synthesis, structural aspects and cytotoxicity of the natural cyclopeptides yunnanins A, C and phakellistatins 1, 10 68
Synthesis and biological evaluation of small Molecules derivatives of the natural Histone deacetylase inhibitor FR235222 68
Fast determination of underivatized gentamicin C components and impurities by LC-MS using a porous graphitic carbon stationary phase 67
Synthesis of kainoids via a highly stereoselective hydroformylation of kainic acid 67
Solid-phase synthesis of conformationally constrained peptidomimetics based on a 3,6-disubstituted-1,4-diazepan-2,5-dione core 66
Synthesis of 2-amino-8-oxodecanoic acids (Aodas) present in natural hystone deacetylase inhibitors 65
A serum nuclear magnetic resonance-based metabolomic signature of antiphospholipid syndrome 64
N-thioalkylcarbazoles derivatives as new anti-proliferative agents: synthesis, characterisation and molecular mechanism evaluation 64
Colorimetric tools for solid-phase organic synthesis 60
Downregulation of hypoxia-related responses by novel antitumor histone deacetylase inhibitors in MDAMB231 breast cancer cells 60
A simple procedure for the transformation of L-glutamic acid into the corresponding γ-aldehyde 59
Chemistry and biology of chromatin remodeling agents: State of art and future perspectives of HDAC inhibitors 59
Total synthesis and structural elucidation of azaspiracid-1. Construction of key building blocks for originally proposed structure 57
Developing Molecular Diversity in the Construction of a Family of Bicyclic Isoxazolines Scaffolds: Control of Regio-and Diastereoselectivities 57
Histone deacetylase inhibitors in the treatment of hematological malignancies 56
Histone deacetylase inhibitor FR235222 sensitizes human prostate adenocarcinoma cells to apoptosis through up-regulation of Annexin A1 54
Design and synthesis of cyclopeptide analogues of the potent histone deacetylase inhibitor FR235222 51
Microwaves enhance cyclisation of tetrapeptides 50
Targeting STAT3 in cancer inhibition 48
Molecular modeling studies toward the structural optimization of new cyclopeptide-based HDAC inhibitors modeled on the natural product FR235222 43
Transformation of glutamic acid into (S)-benzyl 2-(dibenzylamino)-6- (dimethoxyphosphoryl)-5-oxohexanoate for a convenient access to 5-substituted prolines 42
?-Amyloid-acetylcholine molecular interaction: New role of cholinergic mediators in anti-Alzheimer therapy? 39
Steroidal hydroxamic acid derivatives: A structurally novel class of HDAC inhibitors 37
Sensible Improvements Induced by Ionic Liquids in the Reaction of Modified Carbasugars with Bases for the Building of Constrained Carbanucleosides 36
Facile Baeyer–Villiger oxidation of cyclic ketones: conventional versus microwave-assisted approach 34
Structural features of peptides derived from feline immunodeficiency virus TM-Glycoprotein 34
Synthesis and biological evaluation of Santacruzamate-A based analogues 30
Bioelectrospun fibers loaded with Ganoderma lucidum green extracts as a novel bio/medical patch for wound healing applications 27
NANOPOROUS POLYMERS FOR MEDICAL AND COSMECEUTICAL APPLICATIONS 12
Totale 5.845
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Categoria #
all - tutte 16.547
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 16.547
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20215 0 0 0 0 0 0 0 0 0 0 0 5
2021/202262 2 0 0 2 2 1 3 4 9 5 8 26
2022/2023149 10 10 1 11 18 25 12 11 16 17 9 9
2023/2024252 7 16 36 16 15 11 15 14 14 6 30 72
2024/20251.821 131 141 31 43 35 69 212 158 77 171 575 178
2025/20263.426 386 513 471 426 494 125 211 207 287 179 106 21
Totale 5.845