Abstract—Several improvements in the cycloaddition of carboethoxyformonitrile oxide (CEFNO) with different alkenes are observed in the ionic liquids [bmim][BF4] and [bmim][PF6]. The possibility of obtaining good yields of the corresponding isoxazolines opens the way towards parallel collections of glutamic acid (Glu) analogues.
1,3-Cycloaddition of nitrile oxides in ionic liquids. An easier route to 3-carboxy isoxazolines, potential constrained glutamic acid analogues / Conti, Dario; Rodriquez, Manuela; Sega, Alessandro; Taddei, Maurizio. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - 44:(2003), pp. 5327-5330. [10.1016/S0040-4039(03)01195-X]
1,3-Cycloaddition of nitrile oxides in ionic liquids. An easier route to 3-carboxy isoxazolines, potential constrained glutamic acid analogues
RODRIQUEZ, Manuela;
2003
Abstract
Abstract—Several improvements in the cycloaddition of carboethoxyformonitrile oxide (CEFNO) with different alkenes are observed in the ionic liquids [bmim][BF4] and [bmim][PF6]. The possibility of obtaining good yields of the corresponding isoxazolines opens the way towards parallel collections of glutamic acid (Glu) analogues.| File | Dimensione | Formato | |
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