IRIS
LEOSCO, DARIO
 Distribuzione geografica
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Continente #
NA - Nord America 3.202
EU - Europa 2.167
AS - Asia 718
AF - Africa 74
SA - Sud America 11
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 3
Totale 6.179
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Nazione #
US - Stati Uniti d'America 3.104
IT - Italia 681
CN - Cina 633
DE - Germania 410
FI - Finlandia 279
IE - Irlanda 277
NL - Olanda 251
CA - Canada 97
UA - Ucraina 94
SE - Svezia 86
CI - Costa d'Avorio 74
GB - Regno Unito 40
IN - India 30
VN - Vietnam 28
FR - Francia 18
SG - Singapore 9
BE - Belgio 6
IR - Iran 5
AR - Argentina 4
EU - Europa 4
RO - Romania 4
RU - Federazione Russa 4
AU - Australia 3
CH - Svizzera 3
TR - Turchia 3
AT - Austria 2
BG - Bulgaria 2
BR - Brasile 2
DK - Danimarca 2
EC - Ecuador 2
ES - Italia 2
IQ - Iraq 2
JP - Giappone 2
KR - Corea 2
AE - Emirati Arabi Uniti 1
AL - Albania 1
CL - Cile 1
CZ - Repubblica Ceca 1
HK - Hong Kong 1
ID - Indonesia 1
IS - Islanda 1
LI - Liechtenstein 1
MK - Macedonia 1
MX - Messico 1
PE - Perù 1
PK - Pakistan 1
PL - Polonia 1
VE - Venezuela 1
Totale 6.179
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Città #
Chandler 563
Millbury 305
Ashburn 280
Princeton 263
Amsterdam 249
Nanjing 236
Naples 202
Napoli 156
Boston 147
Des Moines 121
Jacksonville 110
Beijing 101
Ottawa 92
Wilmington 83
Nanchang 70
Shenyang 53
Hebei 52
Jiaxing 36
Tianjin 29
Dong Ket 28
Lawrence 27
Washington 27
Houston 24
Norwalk 24
Casavatore 21
Los Angeles 21
Changsha 20
Falls Church 17
Seattle 16
Woodbridge 15
Pune 13
Boardman 12
Milan 12
Mumbai 12
Kronberg 11
Ann Arbor 9
Dublin 9
Helsinki 9
Pozzuoli 9
Redmond 9
Hangzhou 7
Kunming 7
Brembate di Sopra 6
Fremont 6
Lappeenranta 6
Sant'Anastasia 6
Castelfidardo 5
Indiana 5
Rome 5
Saint Paul 5
Augusta 4
Castellammare Di Stabia 4
Concepción del Uruguay 4
Redwood City 4
Vico Equense 4
Buronzo 3
Caserta 3
Formia 3
Jinan 3
Kish 3
Lanzhou 3
Lucé 3
Munich 3
New York 3
Singapore 3
Solagna 3
Viareggio 3
Zurich 3
Avella 2
Bari 2
Brandizzo 2
Bristol 2
Cachan 2
Catanzaro 2
Courcelles 2
Dallas 2
Fabriano 2
Fairfield 2
Genoa 2
Goran 2
Imola 2
Kolkata 2
London 2
Macapá 2
Modica 2
Newark 2
Nocera Inferiore 2
Parma 2
Phoenix 2
Rimini 2
Shanghai 2
Simi Valley 2
Sofia 2
Solofra 2
Toronto 2
Vigonovo 2
Zhengzhou 2
Zola Predosa 2
Andria 1
Aprilia 1
Totale 3.672
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Nome #
Insulin resistance is associated with impaired cardiac sympathetic innervation in patients with heart failure 77
Epicardial adipose tissue has an increased thickness and is a source of inflammatory mediators in patients with calcific aortic stenosis 74
The aging heart: presbycardia [Il cuore senile: la presbicardia] 63
Effects of type 2 diabetes mellitus on coronary microvascular function and myocardial perfusion in patients without obstructive coronary artery disease 55
Autonomic dysfunction in Alzheimer's disease: tools for assessment and review of the literature 51
Sleep-disordered breathing, impaired cardiac adrenergic innervation and prognosis in heart failure 50
Aging exacerbates negative remodeling and impairs endothelial regeneration after balloon injury. 48
Adrenal adrenoceptors in heart failure 47
Age-related effects of platelet activating factor (PAF) in the isolated perfused rat heart. 46
Increased epicardial adipose tissue volume correlates with cardiac sympathetic denervation in patients with heart failure 46
Impact of Malnutrition on Long-Term Mortality in Elderly Patients with Acute Myocardial Infarction. 46
Imbalance Between Interleukin-1β and Interleukin-1 Receptor Antagonist in Epicardial Adipose Tissue Is Associated With Non ST-Segment Elevation Acute Coronary Syndrome 46
Cardiac beta 1-adrenergic receptor blockade promotes angiogenesis in the post-ischemic failing heart via activation of VEGF- and Akt-dependent signalling pathway 45
Exercise training early after acute myocardial infarction reduces stress-induced hypoperfusion and improves left ventricular function 45
Statin therapy modulates thickness and inflammatory profile of human epicardial adipose tissue 44
Exercise restores age-dependent impairment of angiogenesis in rats. 43
Adipokines and coronary artery disease 43
Myocardial β2-adrenoceptor gene delivery promotes coordinated cardiac adaptive remodelling and angiogenesis in heart failure 43
Negative impact of β-arrestin-1 on post-myocardial infarction heart failure via cardiac and adrenal-dependent neurohormonal mechanisms 42
Age-related and heart failure-related beta-adrenergic receptor dysfunction: New therapeutic strategies for the treatment of cardiovascular diseases 42
β-adrenergic receptors and G protein-coupled receptor kinase-2 in Alzheimer's disease: a new paradigm for prognosis and therapy? 41
Changes of plasma norepinephrine and serum N-terminal pro-brain natriuretic peptide after exercise training predict survival in patients with heart failure 41
Prognostic Value of Lymphocyte G Protein-Coupled Receptor Kinase-2 Protein Levels in Patients With Heart Failure 41
Renal function and cardiac adrenergic impairment in patients affected by heart failure 41
Action of magnesium salts on the toxic effects of calcium overload in the isolated and perfused rat heart 40
Alterations of left ventricular deformation and cardiac sympathetic derangement in patients with systolic heart failure: a 3D speckle tracking echocardiography and cardiac ¹²³I-MIBG study 40
GRK2 Regulates α2-Adrenergic Receptor-Dependent Catecholamine Release in Human Adrenal Chromaffin Cells 40
The hypothetical role of potassium conductance on the genesis of R-wave amplitude increase during ischemia in the isolated rat heart. 39
Aortic rupture in patient on oral therapy with levofloxacin 39
Advances in treatment strategies of hypertension in elderly subjects: very low dose combination in first line. 38
Reduction of lymphocyte G protein-coupled receptor kinase-2 (GRK2) after exercise training predicts survival in patients with heart failure. 38
B1-Adrenergic Receptor and Sphingosine-1-Phosphate Receptor 1 (S1PR1) Reciprocal Downregulation Influences Cardiac Hypertrophic Response and Progression to Heart Failure: Protective Role of S1PR1 Cardiac Gene Therapy 38
βARKct gene-therapy improves β2-adrenergic receptor-dependent neoangiogenesis following hindlimb ischemia 38
Sleep-disordered breathing and epicardial adipose tissue in patients with heart failure. 38
The aging heart: presbycardia [Il cuore senile: la presbicardia.] 37
Effects of exercise training on cardiovascular adrenergic system 37
β-adrenergic receptor responsiveness in aging heart and clinical implications 37
The role of endovascular therapy in the treatment of the aortic aneurysms in high-risk subsets. 36
Ruolo del β-bloccante sull’iperattività del Sistema Nervoso Simpatico e sulla produzione di catecolamine recettore α2 -adrenergico-dipendente dalla midollare del surrene in corso di scompenso. 36
Assessing Nephrological Competence among Geriatricians: A Proof of Concept Internet Survey 36
Impact of aging on cardiac sympathetic innervation measured by (123)I-mIBG imaging in patients with systolic heart failure 36
Long-Term Caloric Restriction Improves Cardiac Function, Remodeling, Adrenergic Responsiveness, and Sympathetic Innervation in a Model of Postischemic Heart Failure 36
Immediate and long-term outcome of recanalization of chronic total coronary occlusions 35
The G protein coupled receptor kinase 2 plays an essential role in beta-adrenergic receptor-induced insulin resistance. 35
Age-related effects of ischemia, lidocaine and verapamil on overdrive-induced suppression of ventricular pacemakers in isolated rat heart 35
Impact of diabetes mellitus on lymphocyte GRK2 protein levels in patients with heart failure 35
A new approach to percutaneous coronary revascularization in patients requiring undeferrable non-cardiac surgery 34
Lo scompenso cardiaco: dai meccanismi molecolari al razionale delle nuove strategie di approccio clinico-terapeutico. 34
G protein-coupled receptor kinase-2 svolge un ruolo cruciale nella regolare della funzione endoteliale in vivo e in vitro attraverso la modulazione del signaling del recettore B2-adrenergico. 34
Failure of protective effect of captopril and enalapril on exercise and dipyridamole-induced myocardial ischemia. 33
Protective effect of beta-blockade on dipyridamole-induced myocardial ischaemia. Role of heart rate. 33
beta-1 adrenergic receptor blokade and cardiac beta-2 overexpression stimulates angiogenesis in the failing heart 33
An imbalance between protective and detrimental molecular pathways is associated with right ventricular dysfunction in congenital heart diseases with outflow obstruction 33
Impact of an Innovative Educational Strategy on Medication Appropriate Use and Length of Stay in Elderly Patients 33
β1-Blockade Prevents Post-Ischemic Myocardial Decompensation Via β3AR-Dependent Protective Sphingosine-1 Phosphate Signaling 33
Dipyridamole echocardiography as a useful and safe test in the assessment of coronary artery disease in the elderly 32
Angiotensin II-receptor antagonist losartan does not prevent nitroglycerin tolerance in patients with coronary artery disease 32
Exercise stimulates angiogenesis and improves beta-adrenergic receptor signaling in the failing heart 32
Blockade of ??-adrenoceptors restores the GRK2-mediated adrenal ??(2) -adrenoceptor-catecholamine production axis in heart failure 32
The lipid theory in the pathogenesis of calcific aortic stenosis 32
Efficacia e sicurezza del nuovo stent a rapida reendotelizzazione Genous in pazienti consecutivi sottoposti ad angioplastica coronarica. 31
Sudden onset of coma in a 70-year-old woman with cryoglobulinemia 31
Unrestricted use of endeavour resolute stent in daily clinical practice: a single-centre prospective registry. 31
Adrenergic Drugs Blockers or Enhancers for Cognitive Decline ? What to Choose for Alzheimer's Disease Patients? 31
Validation of the echocardiographic assessment of epicardial adipose tissue thickness at the Rindfleisch fold for the prediction of coronary artery disease 31
beta-2 adrenergic receptors overexpression promotes angiogenesis in the falling myocardium through activation of vascular endothelial growth factor/Akt transduction pathway 30
DIABETES IS ASSOCIATED WITH HIGHER CARDIAC SYMPATHETIC DENERVATION IN PATIENTS WITH LEFT VENTRICLE DYSFUNCTION INDEPENDENTLY FROM HEART FAILURE STATUS 30
Pressure injuries in elderly with acute myocardial infarction 30
Predisposing factors to heart failure in diabetic nephropathy: a look at the sympathetic nervous system hyperactivity 30
C-flip, A protein Required For Embryonic Heart Development, is markedly increased in pressure overload myocardial hypertrophy 29
I nuovi beta-bloccanti nell'insufficienza cardiaca: il paziente difficile 29
Vantaggi del trattamento endoprotesico degli aneurismi aortici in categorie ad alto rischio chirurgico 29
Infectious endocarditis after transcatheter aortic valve implantation in a patient on oral therapy with glucocorticoids 29
Epicardial Adipose Tissue and Postoperative Atrial Fibrillation 29
Ruolo dell’attività fisica sulla prognosi di pazienti anziani affetti da cardiopatia ischemica e sottoposti ad intervento di by-pass aorto-coronarico. 28
Isometric exercise in the non-invasive diagnosis of ischemic cardiopathy. 2-dimensional echocardiography study [Lo sforzo isometrico nella diagnosi non invasiva della cardiopatia ischemica. Studio ecocardiografico bidimensionale] 28
Diabetes is Associated With Higher Lymphocyte G-Protein Coupled Receptor Kinase-2 (grk2) Protein Levels in Patients With Left Ventricle Dysfunction Independently From Heart Failure Status 28
G protein-coupled receptor kinase-2 regola la funzione dei recettori alfa2-adrenergici ed il rilascio di catecolamine nelle cellule cromaffini umane della midollare del surrene. 28
Myocardial pathology induced by aldosterone is dependent on non-canonical activities of G protein-coupled receptor kinases 28
Coinvolgimento del signaling β-adrenergico nella malattia di Alzheimer 28
Calcific aortic stenosis: A peculiar feature of diastolic heart failure in the elderly 28
Echocardiographic Epicardial Adipose Tissue Thickness for Risk Stratification of Patients With Heart Failure 28
Epidemiology and risk factors for heart failure in the elderly 27
Lymphocyte G-protein-coupled receptor kinase-2 is upregulated in patients with Alzheimer's disease. 27
[From bench to bedside: new insights into the treatment of heart failure]. 27
Inhibition of G-protein coupled receptor kinese 2 (grk2) by in vivo gene transfer enhances neoangiogenesis in a rat model of hindlimb ischemia. 27
Beta-adrenergic Receptor Blockade Reduces Sympathetic Overactivation in Heart Failure and Restores Adrenal GRK2-alfa2-adrenergic Receptor-cathecolamine Production Axis. 27
Abciximab in elderly with acute coronary syndrome invasively treated: effect on outcome. 27
The effect of sodium-calcium exchange on the regulation of electrical and mechanical activity of the heart 27
Electrical and mechanical actions of magnesium-sulfate during ischemia and reperfusion on isolated perfused rat-heart 27
The role of endovascular therapy in the treatment of aortic aneurysms in high-risk subsets 27
Correction to :β adrenergic receptor kinase C-terminal peptide gene-therapy improves ß2-adrenergic receptor-dependent neoangiogenesis after hindlimb ischemia (Journal of Pharmacology and Experimental Therapeutics (2016) 356:2 (503–513) DOI: 10.1124/jpet.115.228411) 27
A new approach to percutaneous coronary revascoularization in patient requiring undeferrable non-cardiac surgery. 26
Statins and the elderly: Recent evidence and current indications 26
GRK2 blockade with betaARKct is essential for cardiac beta2-adrenergic receptor signaling towards increased contractility. 26
Reperfusion ventricular arrhythmias in a 75-year-old subject with Prinzmetal's angina. 26
Role of increased cholinergic activity in reperfusion induced ventricular arrhythmias. 26
Circulating levels of cytokines and their site of production in patients with mild to severe chronic heart failure 25
Vantaggi del trattamento endoprotesico degli aneurismi aortici in categorie ad alto rischio chirurgico. 25
Sonde farmacologiche nella diagnosi di cardiopatia ischemica. 25
Totale 3.558
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Categoria #
all - tutte 29.413
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 29.413
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201917 0 0 0 0 0 0 0 0 0 0 2 15
2019/2020870 459 8 27 11 58 5 12 32 22 63 114 59
2020/2021388 26 24 60 18 26 74 24 12 49 9 29 37
2021/20221.497 17 1 4 5 6 65 11 76 309 113 223 667
2022/20231.585 291 78 46 92 176 172 4 128 249 252 80 17
2023/2024995 40 184 221 88 95 139 36 154 13 24 1 0
Totale 6.525