IRIS
TAGLIALATELA, MAURIZIO
 Distribuzione geografica
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Continente #
NA - Nord America 2.898
AS - Asia 2.076
EU - Europa 2.003
SA - Sud America 189
AF - Africa 28
Continente sconosciuto - Info sul continente non disponibili 2
Totale 7.196
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Nazione #
US - Stati Uniti d'America 2.751
SG - Singapore 1.005
IT - Italia 811
HK - Hong Kong 520
CN - Cina 389
RU - Federazione Russa 250
FI - Finlandia 199
NL - Olanda 176
BR - Brasile 172
DE - Germania 154
CA - Canada 136
UA - Ucraina 110
IE - Irlanda 100
VN - Vietnam 95
SE - Svezia 51
GB - Regno Unito 48
AT - Austria 28
CI - Costa d'Avorio 17
PL - Polonia 15
IN - India 14
BE - Belgio 12
FR - Francia 12
TR - Turchia 11
MX - Messico 10
AR - Argentina 8
GR - Grecia 7
BG - Bulgaria 5
ES - Italia 5
IS - Islanda 5
JP - Giappone 5
OM - Oman 5
BD - Bangladesh 4
IL - Israele 4
IR - Iran 4
PK - Pakistan 4
CL - Cile 3
IQ - Iraq 3
MA - Marocco 3
UZ - Uzbekistan 3
AL - Albania 2
CH - Svizzera 2
DK - Danimarca 2
EC - Ecuador 2
EG - Egitto 2
EU - Europa 2
LB - Libano 2
PY - Paraguay 2
RO - Romania 2
TN - Tunisia 2
VE - Venezuela 2
AO - Angola 1
AZ - Azerbaigian 1
BN - Brunei Darussalam 1
BY - Bielorussia 1
DO - Repubblica Dominicana 1
EE - Estonia 1
GE - Georgia 1
KG - Kirghizistan 1
KR - Corea 1
LK - Sri Lanka 1
LT - Lituania 1
ML - Mali 1
MY - Malesia 1
NG - Nigeria 1
NO - Norvegia 1
RS - Serbia 1
SA - Arabia Saudita 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
TG - Togo 1
Totale 7.196
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Città #
Singapore 591
Hong Kong 520
Chandler 384
Millbury 265
Princeton 187
Naples 172
Santa Clara 158
Jacksonville 154
Ashburn 131
Amsterdam 129
Ottawa 119
Nanjing 103
Dong Ket 93
Des Moines 83
Napoli 75
Beijing 71
Boston 62
Wilmington 58
Seattle 47
Milan 43
Nanchang 36
Marano di Napoli 35
Formia 33
Norwalk 33
Shenyang 30
Lawrence 26
Hebei 23
Nuremberg 22
Tianjin 22
Houston 19
Washington 17
Breda 16
Jiaxing 16
Trentola-Ducenta 16
Gdansk 15
Dublin 14
Falkenstein 14
Helsinki 14
Moscow 14
Falls Church 13
São Paulo 13
Verona 13
Guangzhou 12
Changsha 11
The Dalles 11
Vienna 11
Kunming 10
Ann Arbor 9
Boardman 9
Jordanstown 9
Rome 9
Vancouver 9
Cagliari 8
Redmond 8
Istanbul 7
Kronberg 7
Pozzuoli 7
Redwood City 7
Waanrode 7
Belo Horizonte 6
Dearborn 6
Hangzhou 6
Orange 6
Toronto 6
Bhopal 5
Genoa 5
Indiana 5
Mexico City 5
New York 5
Palermo 5
Pescara 5
Reykjavík 5
Rio de Janeiro 5
Salerno 5
San Mateo 5
Sofia 5
Acri 4
Augusta 4
Barano d'Ischia 4
Bovisio-Masciago 4
Cisterna di Latina 4
Fairfield 4
Fisciano 4
Florence 4
Frankfurt am Main 4
Los Angeles 4
Menlo Park 4
Muscat 4
Ningbo 4
Pisa 4
Shenzhen 4
Stockholm 4
Turin 4
Woodbridge 4
Angri 3
Belfast 3
Bisaccia 3
Brugherio 3
Chengdu 3
Fortaleza 3
Totale 4.230
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Nome #
A novel hyperekplexia-causing mutation in the pre-trasmembrane segm 1 of the human glycine receptor alpha 1 subunit reduces membrane expression and impairs gating by agonists 104
Caratterizzazione biochimica e funzionale in oociti di Xenopus Laevis e cellule CHO (Chinese Hamster Ovary Cells) di mutazioni nel gene Kcnq2 riscontrate in famiglie affette da convulsioni benigne neonatali 101
Decreased subunit stability as a novel mechanism for potassium current impairment by a KCNQ2 C terminus mutation causing benign familial neonatal convulsions 79
Tryptamine-based derivatives as Transient Receptor Potential Melastatin type-8 (TRPM8) channel modulators 69
Involvement of KCNQ2 subunits in [3H]dopamine release triggered by depolarization and pre-synaptic muscarinic receptor activation from rat striatal synaptosomes. 65
Decreased Subunit Stability as a Novel Mechanismfor PotassiumCurrent Impairment by a KCNQ2 C Terminus Mutation Causing Benign Familial Neonatal Convulsions 64
A novel mutation in KCNQ2 associated to BFNC, drug resistant epilepsy and mental retardation 63
Pharmacological Targeting Of Neuronal Kv7.2/3 Channels: A Focus On Chemotypes And Receptor Sites 63
Non-invasive real-time in-vivo monitoring of insulin absorption from subcutaneous tissues 62
Addressing the use of PDIF-CN2 molecules in the development of n-type organic field-effect transistors for biosensing applications 60
A novel homozygous KCNQ3 loss-of-function variant causes non-syndromic intellectual disability and neonatal-onset pharmacodependent epilepsy 59
Autism and developmental disability caused by KCNQ3 gain-of-function variants 59
A micro-bioimpedance meter for monitoring insulin bioavailability in personalized diabetes therapy 58
Synthesis and Pharmacological Characterization of Conformationally Restricted Retigabine Analogues as Novel Neuronal Kv7 Channel Activators 57
Early treatment with quinidine in two patients with epilepsy of infancy with migrating focal seizures (EIMFS) due to gain-of-function KCNT1 mutations: functional studies, clinical responses and critical issues for personalized therapy 56
GAIN-OF-FUNCTION DUE TO INCREASED OPENING PROBABILITY BY TWO KCNQ5 PORE VARIANTS CAUSING DEVELOPMENTAL AND/OR EPILEPTIC ENCEPHALOPATHY 56
Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity 55
A novel KCNQ3 mutation in familial epilepsy with focal seizures and intellectual disability 55
Driving with no brakes: Molecular pathophysiology of Kv7 potassium channels 55
The voltage-sensing domain of Kv7.2 channels as a molecular target for epilepsy-causing mutations and anticonvulsants 55
Up-regulation and increased activity of KV3.4 channels and their accessory subunit MinK-related peptide 2 induced by amyloid peptide are involved in apoptotic neuronal death 54
Neuronal potassium channel openers in the management of epilepsy: Role and potential of retigabine 54
Insights into the pathogenesis of ATP1A1-related CMT disease using patient-specific iPSCs 54
Brain distribution of the Na+/Ca2+ exchanger-encoding genes NCX1, NCX2, and NCX3 and their related proteins in the central nervous system 53
Genotype-phenotype correlations in patients with de novo KCNQ2 pathogenic variants 53
A y(+)LAT-1 mutant protein interferes with y(+)LAT-2 activity: implications for the molecular pathogenesis of lysinuric protein intolerance. 52
A novel KCNQ2 K+ channel mutation in benign neonatal convulsions and centrotemporal spikes 52
Gender-related issues in the pharmacology of new anti-obesity drugs 52
Inhibition of depolarization-induced [3H]noradrenaline release from SH-SY5Y human neuroblastoma cells by some second-generation H(1) receptor antagonists through blockade of store-operated Ca(2+) channels (SOCs). 51
Regulation of the human ether-a-gogo related gene (HERG) K+ channels by reactive oxygen species 51
Activation of Kv7 potassium channels inhibits intracellular Ca2+ increases triggered by TRPV1-mediated pain-inducing stimuli in F11 immortalized sensory neurons 51
Generation of an iPSC line (UNINAi001-A) from a girl with neonatal-onset epilepsy and non-syndromic intellectual disability carrying the homozygous KCNQ3 p.PHE534ILEfs*15 variant and of an iPSC line (UNINAi002-A) from a non-carrier, unaffected brother 51
Differential expression of the Na+-Ca2+ exchanger transcripts and proteins in rat brain regions 50
Early-onset epileptic encephalopathy caused by gain-of-function mutations in the voltage sensor of Kv7.2 and Kv7.3 potassium channel subunits 50
M Channels Containing KCNQ2 Subunits Modulate Norepinephrine, Aspartate, and GABA Release from Hippocampal Nerve Terminals 49
Expression pattern of the ether-a-gogo-related (ERG) k+ channel-encoding genes ERG1, ERG2, and ERG3 in the adult rat central nervous system 49
Functional analysis of novel KCNQ2 and KCNQ3 gene variants found in a large pedigree with benign familial neonatal convulsions (BFNC) 49
Lysinuric protein intolerance: identification and functional analysis of mutations of the SLC7A7 gene. 48
Epileptic channelopathies caused by neuronal Kv7 (KCNQ) channel dysfunction 48
Human ether-a-gogo related gene (HERG) K+ channels as pharmacological targets: present and future implications 47
Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate 47
Neurobiology of coronaviruses: Potential relevance for COVID-19 47
“One Health” Approach for Health Innovation and Active Aging in Campania (Italy) 47
Kv7 channel activation reduces brain endothelial cell permeability and prevents kainic acid-induced blood-brain barrier damage 46
Differential expression of the Na+-Ca2+ exchanger transcripts and proteins in rat brain regions. 46
Retigabine and flupirtine exert neuroprotective actions in organotypic hippocampal cultures 46
Benign familial neonatal convulsions caused by altered gating of KCNQ2/KCNQ3 potassium channels 46
Genotype-phenotype correlations in neonatal epilepsies caused by mutations in the voltage sensor of Kv7.2 potassium channel subunits 46
Histidines 578 and 587 in the S5-S6 linker of the human Ether-a-gogo Related Gene-1 K+ channels confer sensitivity to reactive oxygen species 45
A pharmacological study on the possible mechanisms underlying changes in TSH secretion in aged male rats 45
De novo gain-of-function variants in KCNT2 as a novel cause of developmental and epileptic encephalopathy. 45
Histamine induces exocytosis and IL-6 production from human lung macrophages through interaction with H1 receptors 44
Cardiac ion channels and antihistamines: possible mechanisms of cardiotoxicity. 44
NEUROLOGICAL RISKS AND BENEFITS OF CYTOKINE-BASED TREATMENTS IN COVID-19: FROM PRECLINICAL TO CLINICAL EVIDENCE 44
Activation of pre-synaptic M-type K+ channels inhibits [3H]D-aspartate release by reducing Ca2+ entry through P/Q-type voltage-gated Ca2+ channels 43
Expression pattern of the ether-a-gogo-related (ERG) K+ channel-encoding genes ERG1, ERG2, and ERG3 in the adult rat central nervous system. 42
Atypical gating of M-type potassium channels conferred by mutations in uncharged residues in the S4 region of KCNQ2 causing benign familial neonatal convulsions 42
Molecular pathophysiology and pharmacology of the voltage-sensing module of neuronal ion channels 42
Kv7.3 Compound Heterozygous Variants in Early Onset Encephalopathy Reveal Additive Contribution of C-Terminal Residues to PIP2-Dependent K+ Channel Gating 42
Kv7.4 channels regulate potassium permeability in neuronal mitochondria 42
Plasma prolactin levels in the inferior petrosal sinuses in various pituitary disorders during perihypophyseal phlebography 41
Critical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons 41
Epileptic encephalopathy in a patientwith a novel variant in the Kv7.2 S2 transmembrane segment: Clinical, genetic, and functional features 40
Coupling between the voltage-sensing and phosphatase domains of Ci-VSP 40
IgG Autoantibodies Against IgE from Atopic Dermatitis Can Induce the Release of Cytokines and Proinflammatory Mediators from Basophils and Mast Cells 40
KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism 39
Human neoplastic mesothelial cells express voltage-gated sodium channels involved in cell motility 39
Molecular basis for the lack of HERG K+ channel block-related cardiotoxicity by the H1 receptor blocker cetirizine compared with other second-generation antihistamines 39
Blockade of herg K+ channels by second-generation H1 receptor-antagonists may regulate [Ca2+]i oscillations in GH3 cells 39
Adenosine Receptors Modulate the Na+-Ca2+ Exchanger in Cerebral Nerve Endingsa 39
Expression, Localization, and Pharmacological Role of Kv7 Potassium Channels in Skeletal Muscle Proliferation, Differentiation, and Survival after Myotoxic Insults 39
A Novel Kv7.3 Variant in the Voltage-Sensing S4 Segment in a Family With Benign Neonatal Epilepsy: Functional Characterization and in vitro Rescue by β-Hydroxybutyrate 39
Effects of manidipine and nitrendipine enantiomers on the plateau phase of K+-induced intracellular Ca2+ increase in GH3 cells. 38
Modulation of ion channels by reactive oxygen and nitrogen species: a pathophysiological role in brain aging? 38
Expression and function of Kv7.4 channels in rat cardiac mitochondria: Possible targets for cardioprotection 38
Pharmacological blockade of ERG K+ channels and Ca2+ influx through store-operated channels exerts opposite effects on intracellular Ca2+ oscillations in pituitary GH3 cells 37
Pure uptake blockers of dopamine can reduce prolactin secretion: studies with diclofensine 37
Distinct epilepsy phenotypes and response to drugs in KCNA1 gain- and loss-of function variants 37
Differential Vulnerability of Cortical and Cerebellar Neurons in Primary Culture to Oxygen Glucose Deprivation followed by Reoxygenation. 36
Hyperekplexia caused by dominant-negative suppression of GLYRA1 function 36
Manidipine and Nitrendipine R and S enantiomers block voltage-gated Ca2+ channel (VGCC) with different kinetic in GH3 cell 36
Prolonged exposure of pituitary dopaminergic receptors to the phospholipid phosphatidylserine increases their sensitivity to dopamine in aged rats 36
Specification of skeletal muscle differentiation by repressor element-1 silencing transcription factor (REST)-regulated Kv7.4 potassium channels 36
K(V)7 channels regulate muscle tone and nonadrenergic noncholinergic relaxation of the rat gastric fund 36
Gating currents from Kv7 channels carrying neuronal hyperexcitability mutations in the voltage-sensing domain 35
Identification of a Potent Tryptophan-based TRPM8 Antagonist With in vivo Analgesic Activity 34
Cardiac safety of second-generation H1 -antihistamines when updosed in chronic spontaneous urticaria 34
Identification of Drugs Acting as Perpetrators in Common Drug Interactions in a Cohort of Geriatric Patients from Southern Italy and Analysis of the Gene Polymorphisms That Affect Their Interacting Potential 33
Molecular mechanisms involved in beta-amyloid-induced enhancement of voltage-gated K+ channels during neuronal apoptosis 33
Cardiotoxic effects of antihistamines: From basics to clinics (...and back) 33
Correlating the Clinical and Genetic Features of Benign Familial Neonatal Seizures (BFNS) with the Functional Consequences of Underlying Mutations 33
KCNQ3 is the principal target of retigabine in CA1 and subicular excitatory neurons 33
Case report: Marked electroclinical improvement by fluoxetine treatment in a patient with KCNT1-related drug-resistant focal epilepsy 32
Modulation of ion channels by reactive oxygen and nitrogen species: a pathophysiological role in brain aging? 32
Gating consequences of charge neutralization of arginine residues in the S4 segment of K(v)7.2, an epilepsy-linked K+ channel subunit 32
A new Italian FHM2 family: Clinical aspects and functional analysis of the disease-associated mutation 32
Effects of pharmacological manipulation of calcium channels on endogenous dopamine release from tuberoinfundibular neurons 32
Towards the realization of label-free biosensors through impedance spectroscopy integrated with IDES technology. 32
Gating currents from neuronal KV7.4 Channels: General features and correlation with the ionic conductance 32
KCNT2-related disorders: phenotypes, functional and pharmacological properties 31
Totale 4.643
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Categoria #
all - tutte 37.738
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 37.738
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020240 0 0 0 0 0 0 0 0 0 44 101 95
2020/2021498 19 32 31 31 42 78 38 33 39 16 44 95
2021/20221.029 14 7 5 14 15 33 10 38 120 62 213 498
2022/20231.166 229 118 21 148 135 98 8 73 150 132 44 10
2023/2024826 40 93 97 52 60 79 22 71 19 17 189 87
2024/20252.639 306 359 27 50 104 215 726 339 432 81 0 0
Totale 7.533