Distribuzione geografica
Continente #
NA - Nord America 4.725
EU - Europa 2.349
AS - Asia 1.047
AF - Africa 59
SA - Sud America 7
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 3
Totale 8.195
Nazione #
US - Stati Uniti d'America 4.610
IT - Italia 988
CN - Cina 663
SG - Singapore 297
IE - Irlanda 283
FI - Finlandia 277
NL - Olanda 234
SE - Svezia 179
DE - Germania 151
UA - Ucraina 119
CA - Canada 113
GB - Regno Unito 62
CI - Costa d'Avorio 57
IN - India 29
FR - Francia 22
JP - Giappone 18
DK - Danimarca 14
TR - Turchia 14
VN - Vietnam 12
IR - Iran 6
PL - Polonia 6
EU - Europa 5
SI - Slovenia 4
AR - Argentina 3
AU - Australia 3
ES - Italia 3
AT - Austria 2
BE - Belgio 2
CL - Cile 2
ID - Indonesia 2
MX - Messico 2
TW - Taiwan 2
BD - Bangladesh 1
BR - Brasile 1
CZ - Repubblica Ceca 1
EG - Egitto 1
GR - Grecia 1
KR - Corea 1
MA - Marocco 1
PE - Perù 1
RU - Federazione Russa 1
SA - Arabia Saudita 1
UZ - Uzbekistan 1
Totale 8.195
Città #
Chandler 860
Houston 410
Millbury 336
Napoli 318
Princeton 289
Ashburn 239
Amsterdam 231
Nanjing 214
Jacksonville 209
Boston 191
Singapore 171
Beijing 109
Wilmington 109
Ottawa 104
Naples 98
Nanchang 70
Des Moines 69
Cagliari 54
Norwalk 46
Jiaxing 45
Lawrence 42
Shenyang 41
Hebei 37
Woodbridge 37
Falls Church 36
Tianjin 35
Seattle 33
Kronberg 31
Boardman 28
Pune 23
Washington 22
Changsha 21
Rome 20
Kunming 19
Bacoli 14
Augusta 13
Caserta 13
Dong Ket 12
Matsuyama 12
Hangzhou 11
Casoria 10
Lanzhou 9
Ann Arbor 8
Changchun 8
Dublin 8
Milan 8
Redmond 8
San Mateo 8
Verona 8
Cava De' Tirreni 7
Fairfield 7
Hanover 7
Paris 7
San Giorgio del Sannio 7
Formia 6
Los Angeles 6
Montesarchio 6
Mountain View 6
Redwood City 6
Toronto 6
Albany 5
Jinan 5
Lappeenranta 5
Leawood 5
Menlo Park 5
Mondragone 5
Ningbo 5
Taizhou 5
Altavilla Irpina 4
Atella 4
Florence 4
Guangzhou 4
Indiana 4
Mercato San Severino 4
Messina 4
Orange 4
Sciacca 4
Shanghai 4
Torino 4
Zhengzhou 4
Aprilia 3
Auburn 3
Carbonara di Nola 3
Crispano 3
Dalmine 3
Dearborn 3
Frankfurt am Main 3
Fremont 3
Helsinki 3
Hicksville 3
Idstein 3
Livorno 3
Meppel 3
Padula 3
Pozzuoli 3
Saarbrücken 3
Shenzhen 3
Southfield 3
Vercelli 3
Xian 3
Totale 4.966
Nome #
Measurement of glucose homeostasis in vivo: glucose and insulin tolerance tests. 432
• Progetto FIRB RBNE08NKH7 - (Iniziativa MERIT) “Nuovi networks molecolari per il controllo dell’omeostasi energetica: implicazioni per il diabete di tipo 2 e l’obesità”. 142
PTEN targeting: the search for novel insulin sensitisers provides new insight into obesity research. 86
Spot-light on microbiota in obesity and cancer 70
Circulating miRNAs as intercellular messengers, potential biomarkers and therapeutic targets for Type 2 diabetes 66
Potential Mechanisms of Bisphenol A (BPA) Contributing to Human Disease 60
Prep1 Deficiency Affects Olfactory Perception and Feeding Behavior by Impairing BDNF-TrkB Mediated Neurotrophic Signaling 59
Glucose regulates diacylglycerol intracellular levels and protein kinase C activity by modulating diacylglycerol-kinase subcellular localization. 58
Hoxa5 undergoes dynamic DNA methylation and transcriptional repression in the adipose tissue of mice exposed to high-fat diet 56
Phorbol esters induce intracellular accumulation of the anti-apoptotic protein PED/PEA-15 by preventing ubiquitinylation and proteasomal degradation. 55
Quercetin and its derivative Q2 modulate chromatin dynamics in adipogenesis and Q2 prevents obesity and metabolic disorders in rats 52
Adipose microenvironment promotes triple negative breast cancer cell invasiveness and dissemination by producing CCL5 51
Capitolo 15 Diabete Mellito 51
Falsely elevated thyroglobulin and calcitonin due to rheumatoid factor in non-relapsing thyroid carcinoma: A case report 51
Methylglyoxal accumulation de-regulates HoxA5 expression, thereby impairing angiogenesis in glyoxalase 1 knock-down mouse aortic endothelial cells 51
AP20187-mediated activation of a chimeric insulin receptor results in insulin-like actions in skeletal muscle and liver of diabetic mice 50
PED/PEA-15 regulates glucose-induced insulin secretion by restraining potassium channel expression in pancreatic beta-cells 50
Oleic acid promotes prostate cancer malignant phenotype via the G protein-coupled receptor FFA1/GPR40 50
Adenoviral gene transfer of PLD1-D4 enhances insulin sensitivity in mice by disrupting phospholipase D1 interaction with PED/PEA-15. 49
Overexpression of the phosphoprotein enriched in diabetes gene product (Ped/pea-15) in women with polycystic ovary syndrome. 48
Low Dose Bisphenol-A Regulates Inflammatory Cytokines through GPR30 in Mammary Adipose Cells 47
The role of autophagy in neoplastic cell response to oncolytic viruses. 47
Altered PTPRD DNA methylation associates with restricted adipogenesis in healthy first-degree relatives of Type 2 diabetes subjects 47
Pharmacological regulation of the insulin receptor signaling mimics insulin action in cells transduced with viral vectors. 46
Transient Covalent Interactions of Newly-Synthesized Thyroglobulin with Oxidoreductases of the Endoplasmic Reticulum. 45
Glucose-induced expression of the homeotic transcription factor Prep1 is associated with histone post-translational modifications in skeletal muscle 45
Epigenetic modifications of the Zfp/ZNF423 gene control murine adipogenic commitment and are dysregulated in human hypertrophic obesity 45
The co-activator-associated arginine methyltransferase 1 (CARM1) gene is overexpressed in type 2 diabetes 45
A New Horizon of Liquid Biopsy in Thymic Epithelial Tumors: The Potential Utility of Circulating Cell-Free DNA 45
Insulin receptor substrate-2 phosphorylation is necessary for protein kinase czeta activation by insulin in l6hir cells. 44
Bisphenol A environmental exposure and the detrimental effects on human metabolic health: Is it necessary to revise the risk assessment in vulnerable population? 44
Low-Dose bisphenol-A impairs adipogenesis and generates dysfunctional 3T3-L1 adipocytes 44
White cell and platelet content affects the release of bioactive factors in different blood-derived scaffolds. 44
Growth-promoting action and growth factor release by different platelet derivatives. 43
Parkinson-like phenotype in insulin-resistant PED/PEA-15 transgenic mice 43
Prep1, A Homeodomain transcription factor involved in glucose and lipid metabolism 43
Adipose tissue dysfunction as determinant of obesity-associated metabolic complications 43
Adipocyte precursor cells from first degree relatives of type 2 diabetic patients feature changes in hsa-mir-23a-5p, -193a-5p, and -193b-5p and insulin-like growth factor 2 expression 43
IL-3 synergises with basophil-derived IL-4 and IL-13 to promote the alternative activation of human monocytes 42
Prep1 deficiency improves metabolic response in white adipose tissue 42
In skeletal muscle, glucose storage and oxidation are differentially impaired by the IR1152 mutant receptor. 41
Differential role of insulin receptor substrate (IRS)-1 and IRS-2 in L6 skeletal muscle cells expressing the Arg1152 --> Gln insulin receptor. 41
Abnormal glucose transport and GLUT1 cell-surface content in fibroblasts and skeletal muscle from NIDDM and obese subjects 41
Specific CpG hyper-methylation leads to Ankrd26 gene down-regulation in white adipose tissue of a mouse model of diet-induced obesity 41
Peptide antagonists of the PED-hPLD1 binding 41
Citrus aurantium L. dry extracts promote C/ebpβ expression and improve adipocyte differentiation in 3T3-L1 cells. 40
Age-Related Impairment in Insulin Release The Essential Role of beta(2)-Adrenergic Receptor 39
A peptide antagonist of Prep1-p160 interaction improves ceramide-induced insulin resistance in skeletal muscle cells 39
miR-214-dependent increase of PHLPP2 levels mediates the impairment of insulin-stimulated akt activation in mouse aortic endothelial cells exposed to methylglyoxal 39
Glucose regulates insulin mitogenic effect by modulating SHP-2 activation and localization in JAr cells 38
Alterations of PED/PEA-15 gene at the interface of diabetes and Parkinson disease 38
Prep1 regulates angiogenesis through a PGC-1α-mediated mechanism 38
Diagnosis of Flier’s syndrome in a patient with nondiabetic hypoglycemia: a case report and critical appraisal of the literature 38
Molecular cloning and characterization of the human PED/PEA-15 gene promoter reveal antagonistic regulation by hepatocyte nuclear factor 4alpha and chicken ovalbumin upstream promoter transcription factor II. 37
Hepatocyte nuclear factor (HNF)-4alpha-driven epigenetic silencing of the human PED gene. 37
The transcription complex Prep1-Pbx1 regulates the gene expression of tyrosine phosphatases and impairs insulin action in liver cells. 37
Alteration of erythrocyte membrane lipid fluidity in human obesity. 36
Bisphenol-A plasma levels are related to inflammatory markers, visceral obesity and insulin-resistance: a cross-sectional study on adult male population. 36
Human peripheral blood mononuclear cell function and dendritic cell differentiation are affected by bisphenol-A exposure 36
Mutation in a conserved motif next to the insulin receptor key autophosphorylation sites de-regulates kinase activity and impairs insulin action. 35
A Basic-amino-acid Motif Regulates Insulin-receptor (i(r)) Kinase-activity and Metabolic Signaling 35
Pathologic endoplasmic reticulum stress induced by glucotoxic insults inhibits adipocyte differentiation and induces an inflammatory phenotype 35
The Relevance of Insulin Action in the Dopaminergic System 35
Nuove reti molecolari nel controllo della tolleranza al glucosio 34
In L6 cells, glucose induces cytosolic translocation of PKC alpha, trans-activates the insulin receptor kinase and regulates its own uptake 34
• Progetto 2331 - “Nuove molecole per il trattamento del diabete tipo 2”, Fondi MIUR per la ricerca industriale (DM 593/2000). 34
Methylglyoxal impairs insulin signalling and endothelial function both in vitro and in vivo 34
Epigenetic silencing of the ANKRD26 gene correlates to the pro-inflammatory profile and increased cardio-metabolic risk factors in human obesity 34
Phosphoprotein enriched in diabetes (PED/PEA15) promotes migration in hepatocellular carcinoma and confers resistance to sorafenib 34
Peri-Prostatic Adipocyte-Released TGFβ Enhances Prostate Cancer Cell Motility by Upregulation of Connective Tissue Growth Factor 34
Internalization of the constitutively active arginine 1152-->glutamine insulin receptor occurs independently of insulin at an accelerated rate. 33
Insulin induces the interaction of IRS-1 with PKC-alpha and 14-3-3-epsilon 33
PED/PEA-15 controls fibroblast motility and wound closure by ERK1/2-dependent mechanisms 33
Insulin-activated protein kinase Cbeta bypasses Ras and stimulates mitogen-activated protein kinase activity and cell proliferation in muscle cells 33
Unravelling the methylglyoxal effect on the angiogenic process 33
The SGK1 inhibitor SI113 induces autophagy, apoptosis, and endoplasmic reticulum stress in endometrial cancer cells 33
Role of the HIF-1α/Nur77 axis in the regulation of the tyrosine hydroxylase expression by insulin in PC12 cells 33
Zoonotic Risk of Encephalitozoon cuniculi in Animal-Assisted Interventions: Laboratory Strategies for the Diagnosis of Infections in Humans and Animals 33
Activation and mitochondrial translocation of protein kinase Cdelta are necessary for insulin stimulation of pyruvate dehydrogenase complex activity in muscle and liver cells 32
Glucosamine-induced endoplasmic reticulum stress affects GLUT4 expression via activating transcription factor 6 in rat and human skeletal muscle cells. 32
Tribbles homologue 3 (TRIB3) and the insulin-resistance genes in type 2 diabetes. 32
Preliminary data on effects of metformin on PED/PEA-15 cellular levels in obese women with polycystic ovary syndrome. 32
Decreased Insulin Secretion and Insulin Reistance in Beta 2 Adrenergic Receptor Knock-out Mice 32
Adipocyte-released insulin-like growth factor-1 is regulated by glucose and fatty acids and controls breast cancer cell growth in vitro 32
Understanding type 2 diabetes: from genetics to epigenetics 32
The GLP-1 receptor agonists exenatide and liraglutide activate Glucose transport by an AMPK-dependent mechanism 32
Glucose impairs tamoxifen responsiveness modulating connective tissue growth factor in breast cancer cells 32
Periprostatic adipose tissue promotes prostate cancer resistance to docetaxel by paracrine IGF‐1 upregulation of TUBB2B beta‐tubulin isoform 32
Surgical stress and metabolic response after totally laparoscopic right colectomy 32
ZMAT3 hypomethylation contributes to early senescence of preadipocytes from healthy first‐degree relatives of type 2 diabetics 32
In skeletal muscle, advanced glycation end products inhibit insulin action and induce the formation of multimolecular complexes including the receptor for AGEs. 31
Antiphosphotyrosine immunoprecipitation of an insulin-stimulated receptor phosphatase activity from FRTL5 cells. 31
Leptin-stimulated Endothelial Nitric-Oxide Synthase via an AMPK/Akt Signalling Pathway is Attenuated by Interaction with C Reactive Protein. 31
Frontiers: PED/PEA-15, a multifunctional protein controlling cell survival and glucose metabolism. 31
Selective disruption of insulin-like growth factor-1 (IGF-1) signaling via phosphoinositide-dependent kinase-1 prevents the protective effect of IGF-1 on human cancer cell death. 31
Insulin receptor internalization and intracellular sorting are regulated by protein kinase C-zeta and protein kinase b/Akt. 31
AP20817-inducible activation of chimeric insulin receptor mimics insulin action in hepatocytes transduced with AAV 31
Tsh Alters Igf-i Receptor Autophosphorylation and Phosphorylation of the Endogenous Substrate P175 In Follicular Thyroid-cells 31
Bisphenol-A Impairs Insulin Action and Up-Regulates Inflammatory Pathways in Human Subcutaneous Adipocytes and 3T3-L1 Cells. 31
Totale 4.614
Categoria #
all - tutte 37.636
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 37.636

Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201993 0 0 0 0 0 0 0 0 0 0 0 93
2019/20201.264 401 37 123 164 99 47 16 14 39 53 142 129
2020/2021845 24 28 132 28 51 124 213 20 91 34 73 27
2021/20221.913 18 1 9 21 49 56 50 59 314 89 430 817
2022/20232.018 350 197 70 102 253 229 8 144 283 233 110 39
2023/20241.426 79 216 128 117 73 142 31 206 20 21 351 42
Totale 8.996