IRIS
MARINELLI, LUCIANA
 Distribuzione geografica
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Continente #
NA - Nord America 2.342
EU - Europa 1.619
AS - Asia 481
AF - Africa 72
Continente sconosciuto - Info sul continente non disponibili 4
SA - Sud America 1
Totale 4.519
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Nazione #
US - Stati Uniti d'America 2.265
IT - Italia 686
CN - Cina 394
NL - Olanda 213
DE - Germania 166
IE - Irlanda 158
FI - Finlandia 131
UA - Ucraina 84
CA - Canada 76
CI - Costa d'Avorio 70
SE - Svezia 65
GB - Regno Unito 46
VN - Vietnam 34
IN - India 26
FR - Francia 15
ES - Italia 8
IR - Iran 8
BE - Belgio 7
BG - Bulgaria 6
TR - Turchia 6
HR - Croazia 5
SG - Singapore 5
CH - Svizzera 4
EU - Europa 4
JP - Giappone 4
CZ - Repubblica Ceca 3
EE - Estonia 3
PL - Polonia 3
PT - Portogallo 3
AT - Austria 2
EG - Egitto 2
GR - Grecia 2
IS - Islanda 2
RO - Romania 2
BD - Bangladesh 1
CL - Cile 1
CY - Cipro 1
HU - Ungheria 1
IL - Israele 1
KH - Cambogia 1
LT - Lituania 1
MK - Macedonia 1
PA - Panama 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 4.519
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Città #
Chandler 524
Amsterdam 212
Millbury 173
Napoli 149
Princeton 143
Nanjing 139
Naples 104
Jacksonville 102
Ashburn 98
Boston 84
Beijing 71
Ottawa 70
Woodbridge 66
Des Moines 62
Wilmington 57
Dong Ket 34
Nanchang 34
Hebei 26
Shenyang 26
Milan 25
Jiaxing 24
Houston 21
Nürnberg 19
Tianjin 19
Dearborn 18
Lawrence 18
Rome 18
Ann Arbor 16
Norwalk 16
Augusta 15
Seattle 14
Changsha 13
Kronberg 13
Leawood 13
Boardman 12
Florence 12
Dublin 10
Redwood City 10
Falls Church 9
Kunming 9
Pune 9
San Mateo 9
Caserta 8
Los Angeles 7
Quarto 7
Salerno 7
Santa Maria Capua Vetere 7
Torre del Greco 7
Bologna 6
Brussels 6
Edinburgh 6
Guangzhou 6
Jinan 6
Parma 6
Sofia 6
Amorosi 5
Genoa 5
Hangzhou 5
Ningbo 5
Piombino 5
Zagreb 5
Bari 4
Castellammare Di Stabia 4
Chicago 4
Fairfield 4
Filottrano 4
Kilburn 4
Orange 4
Pescara 4
Rho 4
Sagrado 4
Tokyo 4
Acerra 3
Battipaglia 3
Darmstadt 3
Empoli 3
Limbiate 3
Mugnano di Napoli 3
New York 3
Stockholm 3
Taizhou 3
Tallinn 3
Toronto 3
Warsaw 3
Washington 3
Zhengzhou 3
Ardabil 2
Ardore 2
Arzano 2
Athens 2
Avellino 2
Barcelona 2
Capo Di Ponte 2
Cisterna di Latina 2
Frankfurt am Main 2
Garching 2
Giugliano In Campania 2
Helsinki 2
Issiglio 2
Lappeenranta 2
Totale 2.745
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Nome #
Annurca (Malus pumila Miller cv. Annurca) apple as a functional food for the contribution to a healthy balance of plasma cholesterol levels: results of a randomized clinical trial 136
Pharmacophoric Modifications Lead to Superpotent avb3 Integrin Ligands with Suppressed a5b1 Activity 129
Functional Selectivity Revealed by N-Methylation Scanning of Human Urotensin II and Related Peptides 71
Computer-Aided Identification and Lead Optimization of Dual Murine Double Minute 2 and 4 Binders: Structure-Activity Relationship Studies and Pharmacological Activity 65
Screening Platform toward New Anti-HIV Aptamers Set on Molecular Docking and Fluorescence Quenching Techniques 64
Human integrin αvβ5: homology modeling and ligand binding. 62
Click-Chemistry (CuAAC) Trimerization of an αvβ6 Integrin Targeting Ga-68-Peptide: Enhanced Contrast for in-Vivo PET Imaging of Human Lung Adenocarcinoma Xenografts 62
A Healthy Balance of Plasma Cholesterol by a Novel Annurca Apple-Based Nutraceutical Formulation: Results of a Randomized Trial 60
Pharmacological folding chaperones act as allosteric ligands of Frizzled4 58
Shooting for selective drug-like DNA G-quadruplex binders 55
Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells 53
Structure-based lead optimization and biological evaluation of BAX direct activators as novel potential anticancer agents 52
Homology Modeling of NR2B Modulatory Domain of NMDA Receptor and Analysis of Ifenprodil Binding. 50
Probing integrin selectivity: rational design of highly active and selective ligands for the alpha5beta1 and alphavbeta3 integrin receptor. 48
Endogenous vs Exogenous Allosteric Modulators in GPCRs: A dispute for shuttling CB1 among different membrane microenvironments 48
Synthesis, biological activity and molecular modeling of new biphenylic carboxamides as potent and selective CB2 receptor ligands 47
Ligand Binding Analysis for Human alfa 5 beta 1 Integrin: Strategies for Designing New alfa 5 beta 1 Integrin Antagonists 47
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: a novel template for the design of highly selective A2B adenosine receptor antagonists 47
From a Helix to a Small Cycle: Metadynamics-Inspired αvβ6 Integrin Selective Ligands 47
Beyond radio-displacement techniques for Identification of CB1 Ligands: The First Application of a Fluorescence-quenching Assay 46
Exploring the N-Terminal Region of C-X-C Motif Chemokine 12 (CXCL12): Identification of Plasma-Stable Cyclic Peptides As Novel, Potent C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonists 46
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: a novel template for the design of highly selective A2B adenosine receptor antagonists 44
Targeting the Human Telomeric G-Quadruplex Through Virtual Screening Calculations 44
Structural and conformational requisites in DNA quadruplex groove binding: Another piece to the puzzle 43
Analysis of quadruplex ligands by displacement isothermal titration calorimetry 43
Disulfide bond replacement with 1,4‐ and 1,5‐disubstituted [1,2,3]‐triazole on C‐X‐C chemokine receptor type 4 (CXCR4) peptide ligands: small changes that make big differences 43
Novel Bifunctional Quinolonyl Diketo Acid Derivatives as HIV-1 Integrase Inhibitors: Design, Synthesis, Biological Activities, and Mechanism of Action 41
Dual MET and SMO Negative Modulators Overcome Resistance to EGFR Inhibitors in Human Nonsmall Cell Lung Cancer 41
Urotensin-II Receptor Ligands. From Agonist to Antagonist Activity 40
Characterizing the 1,4-Dihydropyridines Binding Interactions in the L-Type Ca2+ Channel: Model Construction and Docking Calculations 40
Syntheses, Biological Evaluation and Molecular Modeling of 18F-labeled 4-Anilidopiperidines as μ-Opioid Receptor Imaging Agents 40
Long non-coding RNA containing ultraconserved genomic region 8 promotes bladder cancer tumorigenesis 40
Structure-Activity Relationships and Biological Characterization of a Novel, Potent, and Serum Stable C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonist 40
Ligand-Based NMR Study of C-X-C Chemokine Receptor Type 4 (CXCR4)-Ligand Interactions on Living Cancer Cells 40
Structural and conformational requisites in DNA quadruplex groove binding: Another piece to the puzzle 39
A New DNA Structural Motif: The G-Triplex 39
Synthesis and Structural Analysis of Cyclic Oligomers Consisting of Furanoid and Pyranoid epsilon-Sugar Amino Acids 38
Docking Studies on avb3 Integrin Ligands: Pharmacophore Refinement and Implications for Drug Design 38
Novel Quinolinonyl Diketo Acid Derivatives as HIV-1 Integrase Inhibitors: Design, Synthesis, and Biological Activities 37
A more detailed picture of the interactions between virtual screening-derived hits and the DNA G-quadruplex: NMR, molecular modelling and ITC studies. 37
Benzothiopyranoindole- and pyridothiopyranoindole-based antiproliferative agents targeting topoisomerases 37
A more detailed picture of the interactions between Virtual Screening-derived Hits and the DNA G-Quadruplex: NMR, Molecular Modeling and ITC Studies 36
New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer 36
Boosting Fmoc Solid-Phase Peptide Synthesis by Ultrasonication 36
Synthesis, Molecular Modeling and mu-Opioid Receptor Affinity of 9,10-Diazatricyclo[4.2.1.12,5] decanes and 2,7-Diazatricyclo[4.4.0.03,8]decanes Structurally Related to 3,8-Diazabicyclo[3.2.1]octanes 35
Shooting for selective druglike G-quadruplex binders: evidence for telomeric DNA damage and tumor cell death 35
Benzofuroxane Derivatives as Multi-Effective Agents for the Treatment of Cardiovascular Diabetic Complications. Synthesis, Functional Evaluation, and Molecular Modeling Studies 34
Shooting for selective drug-like G-quadruplex binders: Evidence for telomeric DNA damage and tumor cell death 34
Chemical modifications in the seed region of miRNAs 221/222 increase the silencing performances in gastrointestinal stromal tumor cells 34
Halting the Spread of Herpes Simplex Virus-1: The Discovery of an Effective Dual αvβ6/αvβ8 Integrin Ligand 34
Conformational Analysis of Furanoid e-Sugar Amino Acid Containing Cyclic Peptides by NMR Spectroscopy, Molecular Dynamics Simulation, and X-ray Crystallography: Evidence for a Novel Turn Structure 33
Synthesis and NMR structure of peptidomimetic alpha4beta7-integrin antagonists. 33
Acetic Acid Aldose Reductase Inhibitors Bearing a Five-Membered Heterocyclic Core with Potent Topical Activity in a Visual Impairment Rat Model. 33
Specific Targeting of Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. 2. Stereoselective Interaction to Overcome the Effects of Drug Resistant Mutations 33
Novel peptidomimetics as BACE-1 inhibitors: synthesis, molecular modeling, and biological studies 33
Structure-Activity Relationship Studies Optimizing the Antiproliferative Activity of Novel Cyclic Somatostatin Analogues Containing a Restrained Cyclic β -Amino Acid 32
State-of-the-art methodologies for the discovery and characterization of DNA G-Quadruplex binders 32
Deepening the Topology of the Translocator Protein Binding Site by Novel N,N-Dialkyl-2-arylindol-3-ylglyoxylamides 32
Targeting CXCR4 reverts the suppressive activity of T-regulatory cells in renal cancer 32
Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors 32
Challenging clinically unresponsive medullary thyroid cancer: Discovery and pharmacological activity of novel RET inhibitors 32
Designed Beta-Turn Mimic Based on the Allylic-Strain Concept: Evaluation of Structural and Biological Features by Incorporation into a Cyclic RGD Peptide (Cyclo(-L-arginylglycyl-L--aspartyl-)) 31
Breaking the dogma of the metal-coordinating carboxylate group in integrin ligands: introducing hydroxamic acids to the MIDAS to tune potency and selectivity 31
New 2-Heterocyclyl-imidazo[2,1-i]purin-5-one Derivatives as Potent and Selective Human A3Adenosine Receptor Antagonists 31
Apoptosis Therapy in Cancer: The First Single-molecule Co-activating p53 and the Translocator Protein in Glioblastoma 31
Discovery of Covalent Inhibitors of Glyceraldehyde-3-phosphate Dehydrogenase, A Target for the Treatment of Malaria 31
Human recombinant beta-secretase immobilized enzyme reactor for fast hits' selection and characterization from a virtual screening library 30
Long lasting inhibition of Mdm2-p53 interaction potentiates mesenchymal stem cell differentiation into osteoblasts 30
Conformational Control of Integrin-Subtype Selectivity in isoDGR Peptide Motifs: A Biological Switch. 29
Applicazione di Metodologie Computazionali nella Scoperta e Sviluppo di Nuovi Agenti per il Trattamento delle Malattie Parassitarie 29
Arylsulfonamide inhibitors of aggrecanases as potential therapeutic agents for osteoarthritis: Synthesis and biological evaluation 29
Biselectivity of isoDGR Peptides for Fibronectin Binding Integrin Subtypes α5β1 and αvβ6: Conformational Control through Flanking Amino Acids 29
Structure-Activity Relationship Refinement and Further Assessment of 4-phenylquinazoline-2-carboxamide Translocator Protein (TSPO) Ligands as Antiproliferative Agents in Human Glioblastoma Tumors. 29
Shooting for Selective Drug-Like DNA G-Quadruplex Binders 29
Ensemble-docking approach on BACE-1: pharmacophore perception and guidelines for drug design 28
Novel N2-substituted pyrazolo[3,4-d]pyrimidine adenosine A3 receptor antagonists: inhibition of A3-mediated human glioblastoma cell proliferation 28
Selective Targeting of Integrin αvβ8 by a Highly Active Cyclic Peptide 28
Progresses in the pursuit of aldose reductase inhibitors: the structure-based lead optimization step. 27
Exploring the chemical space of G-quadruplex binders: Discovery of a novel chemotype targeting the human telomeric sequence 27
Receptor-bound conformation of cilengitide better represented by its solution-state structure than the solid-state structure 27
Development of novel dipeptide-like rhodesain inhibitors containing the 3-bromoisoxazoline warhead in a constrained conformation 27
Probiotic species in the modulation of the anticancer immune response 27
Enriching the arsenal of pharmacological tools against mical2 27
Interfering with the Tumor-Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors 27
Basic Quinolinonyl Diketo Acid Derivatives as Inhibitors of HIV Integrase and their Activity against RNase H Function of Reverse Transcriptase 26
Targeting the KRAS oncogene: Synthesis, physicochemical and biological evaluation of novel G-Quadruplex DNA binders 26
Structural and Conformational Requisites in DNA Quadruplex Groove Binding 25
Identification of novel molecular scaffolds for the design of MMP-13 inhibitors: A first round of lead optimization. 25
Identification of Glycogen Synthase Kinase-3 Inhibitors with a Selective Sting for Glycogen Synthase Kinase-3α 25
The organometallic ferrocene exhibits amplified anti-tumor activity by targeted delivery via highly selective ligands to αvβ3, αvβ6, or α5β1 integrins 25
Tandem Application of Virtual Screening and NMR Experiments in the Discovery of Brand New DNA Quaduplex Groove Binders 24
Applicazione di nuove metodologie computazionali e sintetiche per l'identificazione di inibitori del BACE-1 quali promettenti agenti terapeutici per il morbo di Alzheimer 24
Elucidating the Binding Behavior of Highly Potent COX-2 Selective Inhibitors 24
Identification of anxiolytic/non sedative agents among indol-3-ylglyoxylamides acting as functionally selective agonists at the GABAA alfa2 benzodiazepine receptor 23
From the Pharmacophore to the Homology Model of the Benzodiazepine Receptor: The Indolyglyoxylamides Affair. 23
p53 Functional Inhibitors Behaving Like Pifithrin-? Counteract the Alzheimer Peptide Non-?-amyloid Component Effects in Human SH-SY5Y Cells 23
N-Substituted Quinolinonyl Diketo Acid Derivatives as HIV Integrase Strand Transfer Inhibitors and Their Activity against RNase H Function of Reverse Transcriptase 23
Design, Synthesis, and Biological Evaluation of Novel Aminobisphosphonates Possessing an in Vivo Antitumor Activity Through a γδ -T Lymphocytes-Mediated Activation Mechanism. 22
Ritrovamento di inibitori dell’ADAMTS-5 attraverso metodologie computazionali 22
Design, Synthesis, and Biological Evaluation of 1-Phenylpyrazolo[3,4-e]pyrrolo[3,4-g]indolizine-4,6(1H,5H)-diones as New Glycogen Synthase Kinase-3 beta Inhibitors 22
Totale 3.812
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Categoria #
all - tutte 19.092
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 19.092
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201942 0 0 0 0 0 0 0 0 0 0 12 30
2019/2020642 234 21 27 22 68 24 36 15 15 39 88 53
2020/2021557 33 31 45 30 37 104 42 27 67 17 79 45
2021/2022854 16 3 8 8 16 22 15 41 177 75 94 379
2022/20231.339 174 77 35 146 138 146 0 127 179 211 74 32
2023/2024620 50 107 126 56 43 54 35 120 12 15 2 0
Totale 4.888