IRIS
CERCHIA, CARMEN
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
AS - Asia 1.661
EU - Europa 1.283
NA - Nord America 1.124
SA - Sud America 194
AF - Africa 56
Continente sconosciuto - Info sul continente non disponibili 2
OC - Oceania 2
Totale 4.322
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 1.073
SG - Singapore 924
RU - Federazione Russa 624
CN - Cina 399
IT - Italia 362
BR - Brasile 152
HK - Hong Kong 117
VN - Vietnam 106
DE - Germania 59
FI - Finlandia 44
NL - Olanda 40
GB - Regno Unito 38
IE - Irlanda 34
KR - Corea 30
CI - Costa d'Avorio 27
CA - Canada 21
IN - India 21
MX - Messico 20
FR - Francia 19
SE - Svezia 15
AR - Argentina 14
ZA - Sudafrica 12
ID - Indonesia 10
AT - Austria 9
JP - Giappone 8
ES - Italia 7
IQ - Iraq 7
TR - Turchia 7
BD - Bangladesh 6
CL - Cile 5
EC - Ecuador 5
PL - Polonia 5
VE - Venezuela 5
BE - Belgio 4
LT - Lituania 4
PY - Paraguay 4
RO - Romania 4
UA - Ucraina 4
CO - Colombia 3
KH - Cambogia 3
MA - Marocco 3
NP - Nepal 3
RS - Serbia 3
UZ - Uzbekistan 3
AU - Australia 2
BO - Bolivia 2
BS - Bahamas 2
CY - Cipro 2
CZ - Repubblica Ceca 2
EG - Egitto 2
JM - Giamaica 2
JO - Giordania 2
LV - Lettonia 2
PE - Perù 2
PK - Pakistan 2
SA - Arabia Saudita 2
TW - Taiwan 2
UG - Uganda 2
UY - Uruguay 2
XK - ???statistics.table.value.countryCode.XK??? 2
AE - Emirati Arabi Uniti 1
AZ - Azerbaigian 1
BN - Brunei Darussalam 1
CR - Costa Rica 1
CU - Cuba 1
DM - Dominica 1
DZ - Algeria 1
GM - Gambi 1
GP - Guadalupe 1
GR - Grecia 1
HR - Croazia 1
IR - Iran 1
KE - Kenya 1
KG - Kirghizistan 1
KZ - Kazakistan 1
LS - Lesotho 1
LY - Libia 1
MD - Moldavia 1
MW - Malawi 1
NE - Niger 1
NG - Nigeria 1
NI - Nicaragua 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
TN - Tunisia 1
TT - Trinidad e Tobago 1
TZ - Tanzania 1
Totale 4.322
Salva come PNG Salva come JPEG
Città #
Singapore 472
Moscow 145
Hefei 142
Dallas 125
Hong Kong 114
Ashburn 109
Beijing 95
Chandler 88
Naples 78
Santa Clara 67
Napoli 45
Millbury 43
Ho Chi Minh City 36
Amsterdam 34
Los Angeles 34
Des Moines 29
Seoul 27
Hanoi 25
Milan 22
Princeton 20
Redondo Beach 20
Buffalo 19
São Paulo 19
Boston 17
New York 17
Nanjing 16
Rome 16
Salerno 16
Lawrence 15
Helsinki 14
Munich 14
Nuremberg 12
Wilmington 12
Brooklyn 11
Mexico City 11
Frankfurt am Main 10
Montreal 9
Orem 9
Chicago 8
Haiphong 8
London 8
Stockholm 8
The Dalles 8
Vienna 7
Atlanta 6
Guangzhou 6
Hebei 6
Johannesburg 6
Ottawa 6
Seattle 6
Shenyang 6
Turku 6
Belo Horizonte 5
Casoria 5
Falkenstein 5
Falls Church 5
Kochi 5
Lappeenranta 5
Tokyo 5
Bologna 4
Brussels 4
Buccino 4
Changsha 4
Cologne 4
Dong Ket 4
Dublin 4
Enfield 4
Fairfield 4
Fisciano 4
Goiânia 4
Mumbai 4
Nanchang 4
Phoenix 4
Pune 4
Querétaro 4
Redwood City 4
San Francisco 4
Shanghai 4
Çanakkale 4
Avellino 3
Baghdad 3
Buenos Aires 3
Busto Arsizio 3
Cagliari 3
Camerino 3
Campinas 3
Canoas 3
Casavatore 3
Denver 3
Guarulhos 3
Hải Dương 3
Jiaxing 3
Kyoto 3
Lancaster 3
Manchester 3
Phnom Penh 3
Quảng Ngãi 3
Ribeirão Preto 3
Rimini 3
San Jose 3
Totale 2.280
Salva come PNG Salva come JPEG
Nome #
Unlocking the Potential of Generative Artificial Intelligence in Drug Discovery 152
Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination 144
Discovery of a Novel Small Molecule Inhibitor Targeting the Frataxin/Ubiquitin Interaction via Structure-Based Virtual Screening and Bioassays 124
A compound-based proteomic approach discloses 15-ketoatractyligenin methyl ester as a new PPARγ partial agonist with anti-proliferative ability 122
Novel Non-Peptide Small Molecules Preventing IKKβ/NEMO Association Inhibit NF-κB Activation in LPS-Stimulated J774 Macrophages 120
Cdc25 inhibitors in melanoma cells 117
App maturation and intracellular localization are controlled by a specific inhibitor of 37/67 kda laminin-1 receptor in neuronal cells 117
Discovery of Novel Naphthylphenylketone and Naphthylphenylamine Derivatives as Cell Division Cycle 25B (CDC25B) Phosphatase Inhibitors: Design, Synthesis, Inhibition Mechanism, and in Vitro Efficacy against Melanoma Cell Lines 112
Discovery Of Novel Peroxisome Proliferator-Activated Receptor γ (PPARγ) Scaffolds With Partial Agonist Binding Properties By Integrated In Silico/In Vitro Work Flow 110
Novel Reversible Inhibitors of Xanthine Oxidase Targeting the Active Site of the Enzyme 109
Ligand-based chemoinformatic discovery of a novel small molecule inhibitor targeting CDC25 dual specificity phosphatases and displaying in vitro efficacy against melanoma cells 109
SARS-CoV-2 Entry Inhibitors: Small Molecules and Peptides Targeting Virus or Host Cells 101
Characterization of novel inhibitors of CDC25 phosphatases: biochemical and biological analysis 96
In Silico Identification of Novel Inhibitors Targeting the Homodimeric Interface of Superoxide Dismutase from the Dental Pathogen Streptococcus mutans 95
Antitumor agents 7. Synthesis, antiproliferative activity and molecular modeling of new L-lysine-conjugated pyridophenoxazinones as potent DNA-binding ligands and topoisomerase IIα inhibitors 94
Methyl-Transferase-Like Protein 16 (METTL16): The Intriguing Journey of a Key Epitranscriptomic Player Becoming an Emerging Biological Target 92
Easy access to α-ketoamides as SARS-CoV-2 and MERS Mpro inhibitors via the PADAM oxidation route 92
The antiproliferative and proapoptotic effects of cladosporols A and B are related to their different binding mode as PPARγ ligands 92
Small Molecule Drugs And Targeted Therapy For Melanoma: Current Strategies And Future Directions 91
Development of Novel Selective Peptidomimetics Containing a Boronic Acid Moiety, Targeting the 20S Proteasome as Anticancer Agents 89
Identification of selective 5-LOX and FLAP inhibitors as novel anti-inflammatory agents by ligand-based virtual screening 88
Identification of a new series of amides as non-covalent proteasome inhibitors 88
Deep generative models in the quest for anticancer drugs: ways forward 86
Targeting SARS-CoV-2 Proteases and Polymerase for COVID-19 Treatment: State of the Art and Future Opportunities 86
Synthesis and in vitro cytotoxicity of benzoxazole‐based PPARα/γ antagonists in colorectal cancer cell lines 82
New diphenylmethane derivatives as peroxisome proliferator-activated receptor alpha/gamma dual agonists endowed with anti-proliferative effects and mitochondrial activity 82
Sulfonimide and amide derivatives as novel PPARα antagonists: Synthesis, antiproliferative activity, and docking studies 81
Chiral phenoxyacetic acid analogues inhibit colon cancer cell proliferation acting as PPARγ partial agonists 81
In silico methods to address polypharmacology: Current status, applications and future perspectives 80
Development of novel amides as noncovalent inhibitors of immunoproteasomes 80
Novel inhibitors of signal transducer and activator of transcription 3 signaling pathway: an update on the recent patent literature 79
Selective PPARγ modulators for Type 2 diabetes treatment: How far have we come and what does the future hold? 77
Exploring structural relationships between bioactive and commercial chemical space and developing target hypotheses for compound acquisition 77
Optimization of peptidomimetic boronates bearing a P3 bicyclic scaffold as proteasome inhibitors 73
A chemical modification of a peroxisome proliferator-activated receptor pan agonist produced a shift to a new dual alpha/gamma partial agonist endowed with mitochondrial pyruvate carrier inhibition and antidiabetic properties 70
Enhancing De Novo Drug Design across Multiple Therapeutic Targets with CVAE Generative Models 68
Altered Local Interactions and Long-Range Communications in UK Variant (B.1.1.7) Spike Glycoprotein 67
Impairment of Nucleolin Activity and Phosphorylation by a Trachylobane Diterpene from Psiadia punctulata in Cancer Cells 67
Novel Phenyldiazenyl Fibrate Analogues as PPAR α/γ/δ Pan-Agonists for the Amelioration of Metabolic Syndrome 64
Exploring the Role of N(6)-Substituents in Potent Dual Acting 5'-C-Ethyltetrazolyladenosine Derivatives: Synthesis, Binding, Functional Assays, and Antinociceptive Effects in Mice 62
In Silico Drug Design and Discovery: Big Data for Small Molecule Design 61
A New Antidiabetic Agent Showing Short- and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier Inhibition 59
“DompeKeys”: a set of novel substructure-based descriptors for efficient chemical space mapping, development and structural interpretation of machine learning models, and indexing of large databases 58
New avenues in artificial-intelligence-assisted drug discovery 58
Computational studies of SARS-CoV-2 3clpro: Insights from md simulations 58
Structural basis for PPAR partial or full activation revealed by a novel ligand binding mode 57
“Molecular Anatomy”: a new multi-dimensional hierarchical scaffold analysis tool 54
A chemoinformatics search for peroxisome proliferator-activated receptors ligands revealed a new pan-agonist able to reduce lipid accumulation and improve insulin sensitivity 50
A Series of Ferulic Acid Amides Reveals Unexpected Peroxiredoxin 1 Inhibitory Activity with in vivo Antidiabetic and Hypolipidemic Effects 48
Recent advances in developing PCSK9 inhibitors for lipid-lowering therapy 48
A sulfonimide derivative of bezafibrate as a dual inhibitor of cyclooxygenase-2 and PPARα 46
Identification of the First PPARα/γ Dual Agonist Able to Bind to Canonical and Alternate Sites of PPARγ and to Inhibit its Cdk5-Mediated Phosphorylation 46
Editorial: Recent trends in anti-cancer drug discovery by in silico methods 41
null 26
Challenging triple negative breast cancer through HDAC6 selective inhibition: Novel cap-group identification, structure-activity relationships, computational and biological studies 20
Totale 4.446
Salva come PNG Salva come JPEG
Categoria #
all - tutte 14.195
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 14.195
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202149 0 0 0 0 0 11 1 1 12 7 9 8
2021/2022256 2 3 6 8 18 11 1 3 53 3 51 97
2022/2023277 35 15 16 22 13 29 7 27 39 32 22 20
2023/2024278 18 23 26 22 6 19 7 70 3 4 60 20
2024/20251.520 64 85 14 24 51 92 195 111 62 119 558 145
2025/20261.765 290 238 397 265 456 119 0 0 0 0 0 0
Totale 4.446