TORTORA, GIAMPAOLO
TORTORA, GIAMPAOLO
ZD1839 (‘Iressa’), an EGFR-selective tyrosine kinase inhibitor, enhances taxane activity in bcl-2 overexpressing, multidrug-resistant MCF-7 ADR human breast cancer cells.
2002 Ciardiello, F; Caputo, R; Borriello, G; DEL BUFALO, D; Biroccio, A; Zupi, G; Bianco, Ar; Tortora, Giampaolo
Inhibition of bcl-2 as cancer therapy.
2002 Ciardiello, F; Tortora, Giampaolo
Antitumor activity of combined treatment of human cancer cells with ionizing radiations and anti-epidermal growth factor receptor monoclonal antibody C225 plus type I protein kinase A antisense oligonucleotide.
2000 Bianco, C; Bianco, Roberto; Tortora, Giampaolo; Damiano, Vincenzo; Guerrieri, P; Montemaggi, P; Mendelsohn, J; DE PLACIDO, Sabino; Bianco, Ar; Ciardiello,
Antisense oligonucleotides targeting the epidermal growth factor receptor inhibit proliferation, induce apoptosis and cooperates with cytotoxic drugs in human cancer cell lines.
2001 Ciardiello, F; Caputo, R; Troiani, T; Borriello, Gaetano; Kandimalla, Er; Agrawal, S; Mendelsohn, J; Bianco, Ar; Tortora, Giampaolo
Antitumor activity of sequential treatment with topotecan and anti-epidermal growth factor receptor monoclonal antibody C225.
1999 Ciardiello, F; Bianco, Roberto; Damiano, Vincenzo; DE LORENZO, Sonya; Pepe, Stefano; DE PLACIDO, Sabino; Fan, Z; Mendelsohn, J; Bianco, A. R.; Tortora, Giampaolo
Targeting of Epidermal Growth Factor Receptor and Protein Kinase A : Molecular basis and therapeutic applications.
2000 Tortora, Giampaolo; Ciardiello, F.
Synergistic inhibition of human cancer cell growth by cytotoxic drugs and mixed backbone antisense oligonucleotide targeting protein kinase A.
1997 Tortora, Giampaolo; Caputo, R; Damiano, Vincenzo; Bianco, Roberto; Pepe, Stefano; Bianco, Ar; Jiang, Z; Agrawal, S; Ciardiello, F.
A novel approach in the treatment of cancer: targeting the epidermal growth factor receptor.
2001 Ciardiello, F; Tortora, Giampaolo
Cooperative inhibition of renal cancer growth by anti-epidermal growth factor receptor antibody and protein kinase A antisense oligonucleotide.
1998 Ciardiello, F; Caputo, R; Bianco, Roberto; Damiano, Vincenzo; Pomatico, G; Pepe, Stefano; Bianco, Ar; Agrawal, S; Mendelsohn, J; Tortora, Giampaolo
Phase II trial of cetuximab in combination with fluorouracil, leucovorin, and oxaliplatin in the first-line treatment of metastatic colorectal cancer.
2007 Tabernero, J; Van Cutsem, E; Díaz Rubio, E; Cervantes, A; Humblet, Y; André, T; Van Laethem, Jl; Soulié, P; Casado, E; Verslype, C; Sastre Valera, J; Tortora, Giampaolo; Ciardiello, F; Kisker, O; de Gramont, A.
Rational combination of targeted therapies as a strategy to overcome the mechanisms of resistance to inhibitors of EGFR signaling.
2007 Bianco, Roberto; Damiano, V; Gelardi, T; Daniele, G; Ciardiello, F; Tortora, Giampaolo
EGFR antagonists in cancer treatment.
2008 Ciardiello, F.; Tortora, Giampaolo
The use of xenograft models for the selection of cancer treatments with the EGFR as an example.
2008 Troiani, T; Schettino, C; Martinelli, E; Morgillo, F; Tortora, Giampaolo; Ciardiello, F.
Synergistic anti-proliferative and pro-apoptotic activity of combined therapy with bortezomib, a proteasome inhibitor, with anti-epidermal growth factor receptor (EGFR) drugs in human cancer cells.
2008 Cascone, T; Morelli, Mp; Morgillo, F; Kim, Wy; Rodolico, G; Pepe, Stefano; Tortora, Giampaolo; Berrino, L; Lee, Hy; Heymach, Jv; Ciardiello, F.
Cooperative antitumor effect of multitargeted kinase inhibitor ZD6474 and ionizing radiation in glioblastoma.
2005 Damiano, V; Melisi, D; Bianco, C; Raben, D; Caputo, R; Fontanini, G; Bianco, Roberto; Ryan, A; Bianco, Ar; DE PLACIDO, Sabino; Ciardiello, F; Tortora, Giampaolo
Anti-epidermal growth factor receptor drugs in cancer therapy.
2002 Ciardiello, F; Tortora, Giampaolo
Epidermal growth factor receptor (EGFR) as a target in cancer therapy: understanding the role of receptor expression and other molecular determinants that could influence the response to anti-EGFR drugs.
2003 Ciardiello, F; Tortora, Giampaolo
8-Chloro-cyclic AMP inhibits autocrine and angiogenic growth factor production in human colorectal and breast cancer.
1997 Bianco, C; Tortora, Giampaolo; Baldassarre, G; Caputo, R; Fontanini, G; Chine, S; Bianco, Ar; Ciardiello, F.
Inhibition of growth factors production and angiogenesis in human cancer cells by ZD1839 (Iressa), a selective epidermal growth factor receptor tyrosine kinase inhibitor.
2001 Ciardiello, F; Caputo, R; Bianco, Roberto; Damiano, Vincenzo; Fontanini, G; Cuccato, S; DE PLACIDO, Sabino; Bianco, Ar; Tortora, Giampaolo
Oral administration of a novel taxane, an antisense oligonucleotide targeting protein kinase A, and the epidermal growth factor receptor inhibitor Iressa causes cooperative antitumor and antiangiogenic activity.
2001 Tortora, Giampaolo; Caputo, R; Damiano, Vincenzo; Fontanini, G; Melisi, Davide; Veneziani, BIANCA MARIA; Zunino, F; Bianco, Ar; Ciardiello, F.
| Titolo | Tipologia | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|---|
| ZD1839 (‘Iressa’), an EGFR-selective tyrosine kinase inhibitor, enhances taxane activity in bcl-2 overexpressing, multidrug-resistant MCF-7 ADR human breast cancer cells. | 1.1 Articolo in rivista | 2002 | Ciardiello, F; Caputo, R; Borriello, G; DEL BUFALO, D; Biroccio, A; Zupi, G; Bianco, Ar; Tortora, Giampaolo | |
| Inhibition of bcl-2 as cancer therapy. | 1.1 Articolo in rivista | 2002 | Ciardiello, F; Tortora, Giampaolo | |
| Antitumor activity of combined treatment of human cancer cells with ionizing radiations and anti-epidermal growth factor receptor monoclonal antibody C225 plus type I protein kinase A antisense oligonucleotide. | 1.1 Articolo in rivista | 2000 | Bianco, C; Bianco, Roberto; Tortora, Giampaolo; Damiano, Vincenzo; Guerrieri, P; Montemaggi, P; Mendelsohn, J; DE PLACIDO, Sabino; Bianco, Ar; Ciardiello, | |
| Antisense oligonucleotides targeting the epidermal growth factor receptor inhibit proliferation, induce apoptosis and cooperates with cytotoxic drugs in human cancer cell lines. | 1.1 Articolo in rivista | 2001 | Ciardiello, F; Caputo, R; Troiani, T; Borriello, Gaetano; Kandimalla, Er; Agrawal, S; Mendelsohn, J; Bianco, Ar; Tortora, Giampaolo | |
| Antitumor activity of sequential treatment with topotecan and anti-epidermal growth factor receptor monoclonal antibody C225. | 1.1 Articolo in rivista | 1999 | Ciardiello, F; Bianco, Roberto; Damiano, Vincenzo; DE LORENZO, Sonya; Pepe, Stefano; DE PLACIDO, Sabino; Fan, Z; Mendelsohn, J; Bianco, A. R.; Tortora, Giampaolo | |
| Targeting of Epidermal Growth Factor Receptor and Protein Kinase A : Molecular basis and therapeutic applications. | 1.1 Articolo in rivista | 2000 | Tortora, Giampaolo; Ciardiello, F. | |
| Synergistic inhibition of human cancer cell growth by cytotoxic drugs and mixed backbone antisense oligonucleotide targeting protein kinase A. | 1.1 Articolo in rivista | 1997 | Tortora, Giampaolo; Caputo, R; Damiano, Vincenzo; Bianco, Roberto; Pepe, Stefano; Bianco, Ar; Jiang, Z; Agrawal, S; Ciardiello, F. | |
| A novel approach in the treatment of cancer: targeting the epidermal growth factor receptor. | 1.1 Articolo in rivista | 2001 | Ciardiello, F; Tortora, Giampaolo | |
| Cooperative inhibition of renal cancer growth by anti-epidermal growth factor receptor antibody and protein kinase A antisense oligonucleotide. | 1.1 Articolo in rivista | 1998 | Ciardiello, F; Caputo, R; Bianco, Roberto; Damiano, Vincenzo; Pomatico, G; Pepe, Stefano; Bianco, Ar; Agrawal, S; Mendelsohn, J; Tortora, Giampaolo | |
| Phase II trial of cetuximab in combination with fluorouracil, leucovorin, and oxaliplatin in the first-line treatment of metastatic colorectal cancer. | 1.1 Articolo in rivista | 2007 | Tabernero, J; Van Cutsem, E; Díaz Rubio, E; Cervantes, A; Humblet, Y; André, T; Van Laethem, Jl; Soulié, P; Casado, E; Verslype, C; Sastre Valera, J; Tortora, Giampaolo; Ciardiello, F; Kisker, O; de Gramont, A. | |
| Rational combination of targeted therapies as a strategy to overcome the mechanisms of resistance to inhibitors of EGFR signaling. | 1.1 Articolo in rivista | 2007 | Bianco, Roberto; Damiano, V; Gelardi, T; Daniele, G; Ciardiello, F; Tortora, Giampaolo | |
| EGFR antagonists in cancer treatment. | 1.1 Articolo in rivista | 2008 | Ciardiello, F.; Tortora, Giampaolo | |
| The use of xenograft models for the selection of cancer treatments with the EGFR as an example. | 1.1 Articolo in rivista | 2008 | Troiani, T; Schettino, C; Martinelli, E; Morgillo, F; Tortora, Giampaolo; Ciardiello, F. | |
| Synergistic anti-proliferative and pro-apoptotic activity of combined therapy with bortezomib, a proteasome inhibitor, with anti-epidermal growth factor receptor (EGFR) drugs in human cancer cells. | 1.1 Articolo in rivista | 2008 | Cascone, T; Morelli, Mp; Morgillo, F; Kim, Wy; Rodolico, G; Pepe, Stefano; Tortora, Giampaolo; Berrino, L; Lee, Hy; Heymach, Jv; Ciardiello, F. | |
| Cooperative antitumor effect of multitargeted kinase inhibitor ZD6474 and ionizing radiation in glioblastoma. | 1.1 Articolo in rivista | 2005 | Damiano, V; Melisi, D; Bianco, C; Raben, D; Caputo, R; Fontanini, G; Bianco, Roberto; Ryan, A; Bianco, Ar; DE PLACIDO, Sabino; Ciardiello, F; Tortora, Giampaolo | |
| Anti-epidermal growth factor receptor drugs in cancer therapy. | 1.1 Articolo in rivista | 2002 | Ciardiello, F; Tortora, Giampaolo | |
| Epidermal growth factor receptor (EGFR) as a target in cancer therapy: understanding the role of receptor expression and other molecular determinants that could influence the response to anti-EGFR drugs. | 1.1 Articolo in rivista | 2003 | Ciardiello, F; Tortora, Giampaolo | |
| 8-Chloro-cyclic AMP inhibits autocrine and angiogenic growth factor production in human colorectal and breast cancer. | 1.1 Articolo in rivista | 1997 | Bianco, C; Tortora, Giampaolo; Baldassarre, G; Caputo, R; Fontanini, G; Chine, S; Bianco, Ar; Ciardiello, F. | |
| Inhibition of growth factors production and angiogenesis in human cancer cells by ZD1839 (Iressa), a selective epidermal growth factor receptor tyrosine kinase inhibitor. | 1.1 Articolo in rivista | 2001 | Ciardiello, F; Caputo, R; Bianco, Roberto; Damiano, Vincenzo; Fontanini, G; Cuccato, S; DE PLACIDO, Sabino; Bianco, Ar; Tortora, Giampaolo | |
| Oral administration of a novel taxane, an antisense oligonucleotide targeting protein kinase A, and the epidermal growth factor receptor inhibitor Iressa causes cooperative antitumor and antiangiogenic activity. | 1.1 Articolo in rivista | 2001 | Tortora, Giampaolo; Caputo, R; Damiano, Vincenzo; Fontanini, G; Melisi, Davide; Veneziani, BIANCA MARIA; Zunino, F; Bianco, Ar; Ciardiello, F. |