TORTORA, GIAMPAOLO
TORTORA, GIAMPAOLO
Phase I clinical study with 8-Chloro-cAMP and evaluation of immunological effects in cancer patients.
1995 Tortora, Giampaolo; Ciardiello, F.; Pepe, Stefano; Tagliaferri, P.; Ruggiero, A.; Bianco, C.; Guarrasi, R.; Miki, K.; Bianco, A. R.
Down-regulation of type I protein kinase A by transfection of human breast cancer cells with an epidermal growth factor receptor antisense expression vector.
1998 Ciardiello, F; Dixit, M; di Isernia, G; Damiano, Vincenzo; Bianco, Roberto; Bianco, Ar; Arteaga, Cl; Tortora, Giampaolo
Cooperative antitumor effect of mixed backbone oligonucleotides targeting protein kinase A in combination with cytotoxic drugs or biologic agents.
1998 Tortora, Giampaolo; Caputo, R; Damiano, Vincenzo; Bianco, Roberto; Pepe, Stefano; Pomatico, G; Bianco, Ar; Jiang, Z; Agrawal, S; Ciardiello, F.
The cAMP-dependent protein kinase type I is involved in hypersensitivity of human breast cells to topoisomerase II inhibitors.
1995 Tortora, Giampaolo; Ciardiello, F.; Damiano, Vincenzo; Pepe, Stefano; Bianco, C.; di Isernia, G.; Davies, S. L.; North, P.; Harris, A. L.; Hickson, I. D.; Bianco, A. R.
Inhibitors of HER/erB receptors: biological bases and clinical applications
2006 Damiano, V; Bianco, Roberto; Gelardi, T; Ciardiello, F; Tortora, Giampaolo
Mechanisms of resistance to HER/erbB inhibitors
2007 Bianco, Roberto; Damiano, V; Gelardi, T; Ciardiello, F; Tortora, Giampaolo
Differential sensitivity to non-MHC-restricted rIL-2 activated lymphocyte killing of human mammary epithelial MCF-10A cells overexpressing oncogenes or PKA subunits.
1996 Tagliaferri, P.; Tortora, Giampaolo; Guarrasi, R.; Damiano, Vincenzo; Ruggiero, A.; Morelli, D.; Caraglia, M.; Bianco, Roberto; di Isernia, G.; Pepe, Stefano; Arteaga, C. L.; Langton Webster, B. C.; Bianco, A. R.; Ciardiello, F.
Effects of mutant p53 genes on transformation of human mammary epithelial cells.
1994 Bianco, C.; Tortora, Giampaolo; Basolo, F.; Fiore, L.; Fontanini, G.; Merlo, G.; Salomon, D. S.; Bianco, A. R.; Ciardiello, F.
Inhibition of Cripto expression and tumorigenicity in human colon cancer cells by antisense RNA and oligodeoxynucleotides.
1994 Ciardiello, F.; Tortora, Giampaolo; Bianco, C.; Selvam, M. P.; Basolo, F.; Fontanini, G.; Pacifico, F.; Normanno, N.; Brandt, R.; Persico, M. G.; Salomon, D. S.; Bianco, A. R.
LY2109761, a Novel Transforming Growth Factor ß Receptor type I and II dual inhibitor, as a Therapeutic Approach to Suppressing Pancreatic Cancer Metastasis.
2008 Melisi, D; Ishiyama, S; Sclabas, Gm; Fleming, B. J.; Xia, Q; Tortora, Giampaolo; Abbruzzese, Jl; Chiao, P. J.
Inhibition of mTOR pathway by everolimus cooperates with EGFR inhibitors in human tumors sensitive and resistant to anti-EGFR drugs
2008 Bianco, Roberto; Garofalo, S; Rosa, R; Damiano, V; Gelardi, T; Daniele, G; Ciardiello, F; Tortora, Giampaolo
Phase II trial of cetuximab in combination with fluorouracil, leucovorin, and oxaliplatin in the first-line treatment of metastatic colorectal cancer.
2007 Tabernero, J; Van Cutsem, E; Díaz Rubio, E; Cervantes, A; Humblet, Y; André, T; Van Laethem, Jl; Soulié, P; Casado, E; Verslype, C; Sastre Valera, J; Tortora, Giampaolo; Ciardiello, F; Kisker, O; de Gramont, A.
Rational combination of targeted therapies as a strategy to overcome the mechanisms of resistance to inhibitors of EGFR signaling.
2007 Bianco, Roberto; Damiano, V; Gelardi, T; Daniele, G; Ciardiello, F; Tortora, Giampaolo
Combined targeting of EGFR and VEGF-dependent pathways: rationale, preclinical studies and clinical applications
2008 Tortora, Giampaolo; Ciardiello, F; Gasparini, G.
Enzastaurin inhibits tumors sensitive and resistant to anti-EGFR drugs
2008 Gelardi, Teresa; Caputo, R; Damiano, Vincenzo; Daniele, Gennaro; Pepe, Stefano; Ciardiello, F; Lahn, M; Bianco, Roberto; Tortora, Giampaolo
8-Chloro-cAMP enhances the growth inhibitory effect of cytotoxic drugs in human colon cancer cells
1996 di Isernia, G.; Ciardiello, F.; Sandomenico, C.; Pepe, Stefano; Bianco, A. R.; Tortora, Giampaolo
ZD1839 (Iressa): preclinical studies and pharmacology.
2002 Ciardiello, Fortunato; Tortora, Giampaolo; DE PLACIDO, Sabino; Bianco, ANGELO RAFFAELE
Strategies for multiple signalling inhibition.
2004 Tortora, Giampaolo; Bianco, Roberto; Daniele, Gennaro
Differential effects of type I and type II protein kinase A isoforms on chinese hamster ovary cell cycle and proliferation.
1994 Tortora, Giampaolo; Pepe, Stefano; Bianco, C.; Damiano, Vincenzo; Ruggiero, A.; Baldassarre, G.; Corbo, C.; Cho Chung, Y. S.; Bianco, A. R.; Ciardiello, F.
The RIalfa subunit of protein kinase A controls serum dependency and entry into cell cycle of human mammary epithelial cells.
1994 Tortora, Giampaolo; Pepe, Stefano; Bianco, C.; Baldassarre, G.; Budillon, A.; Clair, T.; Cho Chung, Y. S.; Bianco, A. R.; Ciardiello, F.
| Titolo | Tipologia | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|---|
| Phase I clinical study with 8-Chloro-cAMP and evaluation of immunological effects in cancer patients. | 1.1 Articolo in rivista | 1995 | Tortora, Giampaolo; Ciardiello, F.; Pepe, Stefano; Tagliaferri, P.; Ruggiero, A.; Bianco, C.; Guarrasi, R.; Miki, K.; Bianco, A. R. | |
| Down-regulation of type I protein kinase A by transfection of human breast cancer cells with an epidermal growth factor receptor antisense expression vector. | 1.1 Articolo in rivista | 1998 | Ciardiello, F; Dixit, M; di Isernia, G; Damiano, Vincenzo; Bianco, Roberto; Bianco, Ar; Arteaga, Cl; Tortora, Giampaolo | |
| Cooperative antitumor effect of mixed backbone oligonucleotides targeting protein kinase A in combination with cytotoxic drugs or biologic agents. | 1.1 Articolo in rivista | 1998 | Tortora, Giampaolo; Caputo, R; Damiano, Vincenzo; Bianco, Roberto; Pepe, Stefano; Pomatico, G; Bianco, Ar; Jiang, Z; Agrawal, S; Ciardiello, F. | |
| The cAMP-dependent protein kinase type I is involved in hypersensitivity of human breast cells to topoisomerase II inhibitors. | 1.1 Articolo in rivista | 1995 | Tortora, Giampaolo; Ciardiello, F.; Damiano, Vincenzo; Pepe, Stefano; Bianco, C.; di Isernia, G.; Davies, S. L.; North, P.; Harris, A. L.; Hickson, I. D.; Bianco, A. R. | |
| Inhibitors of HER/erB receptors: biological bases and clinical applications | 2.1 Contributo in volume (Capitolo o Saggio) | 2006 | Damiano, V; Bianco, Roberto; Gelardi, T; Ciardiello, F; Tortora, Giampaolo | |
| Mechanisms of resistance to HER/erbB inhibitors | 2.1 Contributo in volume (Capitolo o Saggio) | 2007 | Bianco, Roberto; Damiano, V; Gelardi, T; Ciardiello, F; Tortora, Giampaolo | |
| Differential sensitivity to non-MHC-restricted rIL-2 activated lymphocyte killing of human mammary epithelial MCF-10A cells overexpressing oncogenes or PKA subunits. | 1.1 Articolo in rivista | 1996 | Tagliaferri, P.; Tortora, Giampaolo; Guarrasi, R.; Damiano, Vincenzo; Ruggiero, A.; Morelli, D.; Caraglia, M.; Bianco, Roberto; di Isernia, G.; Pepe, Stefano; Arteaga, C. L.; Langton Webster, B. C.; Bianco, A. R.; Ciardiello, F. | |
| Effects of mutant p53 genes on transformation of human mammary epithelial cells. | 1.1 Articolo in rivista | 1994 | Bianco, C.; Tortora, Giampaolo; Basolo, F.; Fiore, L.; Fontanini, G.; Merlo, G.; Salomon, D. S.; Bianco, A. R.; Ciardiello, F. | |
| Inhibition of Cripto expression and tumorigenicity in human colon cancer cells by antisense RNA and oligodeoxynucleotides. | 1.1 Articolo in rivista | 1994 | Ciardiello, F.; Tortora, Giampaolo; Bianco, C.; Selvam, M. P.; Basolo, F.; Fontanini, G.; Pacifico, F.; Normanno, N.; Brandt, R.; Persico, M. G.; Salomon, D. S.; Bianco, A. R. | |
| LY2109761, a Novel Transforming Growth Factor ß Receptor type I and II dual inhibitor, as a Therapeutic Approach to Suppressing Pancreatic Cancer Metastasis. | 1.1 Articolo in rivista | 2008 | Melisi, D; Ishiyama, S; Sclabas, Gm; Fleming, B. J.; Xia, Q; Tortora, Giampaolo; Abbruzzese, Jl; Chiao, P. J. | |
| Inhibition of mTOR pathway by everolimus cooperates with EGFR inhibitors in human tumors sensitive and resistant to anti-EGFR drugs | 1.1 Articolo in rivista | 2008 | Bianco, Roberto; Garofalo, S; Rosa, R; Damiano, V; Gelardi, T; Daniele, G; Ciardiello, F; Tortora, Giampaolo | |
| Phase II trial of cetuximab in combination with fluorouracil, leucovorin, and oxaliplatin in the first-line treatment of metastatic colorectal cancer. | 1.1 Articolo in rivista | 2007 | Tabernero, J; Van Cutsem, E; Díaz Rubio, E; Cervantes, A; Humblet, Y; André, T; Van Laethem, Jl; Soulié, P; Casado, E; Verslype, C; Sastre Valera, J; Tortora, Giampaolo; Ciardiello, F; Kisker, O; de Gramont, A. | |
| Rational combination of targeted therapies as a strategy to overcome the mechanisms of resistance to inhibitors of EGFR signaling. | 1.1 Articolo in rivista | 2007 | Bianco, Roberto; Damiano, V; Gelardi, T; Daniele, G; Ciardiello, F; Tortora, Giampaolo | |
| Combined targeting of EGFR and VEGF-dependent pathways: rationale, preclinical studies and clinical applications | 1.1 Articolo in rivista | 2008 | Tortora, Giampaolo; Ciardiello, F; Gasparini, G. | |
| Enzastaurin inhibits tumors sensitive and resistant to anti-EGFR drugs | 1.1 Articolo in rivista | 2008 | Gelardi, Teresa; Caputo, R; Damiano, Vincenzo; Daniele, Gennaro; Pepe, Stefano; Ciardiello, F; Lahn, M; Bianco, Roberto; Tortora, Giampaolo | |
| 8-Chloro-cAMP enhances the growth inhibitory effect of cytotoxic drugs in human colon cancer cells | 1.1 Articolo in rivista | 1996 | di Isernia, G.; Ciardiello, F.; Sandomenico, C.; Pepe, Stefano; Bianco, A. R.; Tortora, Giampaolo | |
| ZD1839 (Iressa): preclinical studies and pharmacology. | 1.1 Articolo in rivista | 2002 | Ciardiello, Fortunato; Tortora, Giampaolo; DE PLACIDO, Sabino; Bianco, ANGELO RAFFAELE | |
| Strategies for multiple signalling inhibition. | 1.1 Articolo in rivista | 2004 | Tortora, Giampaolo; Bianco, Roberto; Daniele, Gennaro | |
| Differential effects of type I and type II protein kinase A isoforms on chinese hamster ovary cell cycle and proliferation. | 1.1 Articolo in rivista | 1994 | Tortora, Giampaolo; Pepe, Stefano; Bianco, C.; Damiano, Vincenzo; Ruggiero, A.; Baldassarre, G.; Corbo, C.; Cho Chung, Y. S.; Bianco, A. R.; Ciardiello, F. | |
| The RIalfa subunit of protein kinase A controls serum dependency and entry into cell cycle of human mammary epithelial cells. | 1.1 Articolo in rivista | 1994 | Tortora, Giampaolo; Pepe, Stefano; Bianco, C.; Baldassarre, G.; Budillon, A.; Clair, T.; Cho Chung, Y. S.; Bianco, A. R.; Ciardiello, F. |