IRIS
ORIENTE, FRANCESCO
 Distribuzione geografica
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Continente #
NA - Nord America 1.292
EU - Europa 625
AS - Asia 223
AF - Africa 12
Totale 2.152
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Nazione #
US - Stati Uniti d'America 1.245
IT - Italia 200
CN - Cina 194
IE - Irlanda 84
NL - Olanda 75
FI - Finlandia 70
DE - Germania 57
UA - Ucraina 54
CA - Canada 47
SE - Svezia 40
GB - Regno Unito 23
IN - India 19
CI - Costa d'Avorio 12
FR - Francia 10
PL - Polonia 6
JP - Giappone 5
TR - Turchia 4
BG - Bulgaria 3
DK - Danimarca 1
EE - Estonia 1
ES - Italia 1
SG - Singapore 1
Totale 2.152
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Città #
Chandler 264
Ashburn 105
Millbury 76
Princeton 76
Jacksonville 74
Amsterdam 72
Boston 70
Nanjing 56
Napoli 49
Ottawa 43
Wilmington 30
Beijing 26
Pune 19
Seattle 19
Des Moines 18
Nanchang 17
Hebei 16
Naples 14
Houston 13
Lawrence 13
Tianjin 13
Shenyang 12
Jiaxing 9
Falls Church 8
Kronberg 8
Kunming 8
Norwalk 8
Washington 7
Woodbridge 7
Boardman 6
Changsha 6
Hangzhou 6
Augusta 5
Caserta 5
Florence 4
Toronto 4
Zhengzhou 4
Auburn 3
Changchun 3
Crispano 3
Fairfield 3
Guangzhou 3
Hanover 3
Hicksville 3
Idstein 3
Kagoya 3
Meppel 3
Ningbo 3
Paris 3
Rome 3
Shenzhen 3
Sofia 3
Casoria 2
Citta Sant'angelo 2
Dalmine 2
Dublin 2
Frankfurt am Main 2
Hackney 2
Jinan 2
Los Angeles 2
Maddaloni 2
Redmond 2
San Mateo 2
Scafati 2
Shanghai 2
Taizhou 2
Ann Arbor 1
Bari 1
Brescia 1
Cardito 1
Castellammare Di Stabia 1
Cava De' Tirreni 1
Chiba 1
Council Bluffs 1
Falkenstein 1
Fossombrone 1
Frederiksberg 1
Fuzhou 1
Köln 1
Leawood 1
London 1
Magenta 1
Mainz 1
Melito Di Napoli 1
Milan 1
Mountain View 1
New Albany 1
Nocera Inferiore 1
Orange 1
Padula 1
Pesaro 1
Pompei 1
Redwood City 1
Rende 1
Roseto degli Abruzzi 1
Saarbrücken 1
Saintes 1
San Cipriano Picentino 1
Shaoxing 1
Sutton 1
Totale 1.297
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Nome #
Prep1 Deficiency Affects Olfactory Perception and Feeding Behavior by Impairing BDNF-TrkB Mediated Neurotrophic Signaling 58
Potential Mechanisms of Bisphenol A (BPA) Contributing to Human Disease 58
Glucose regulates diacylglycerol intracellular levels and protein kinase C activity by modulating diacylglycerol-kinase subcellular localization. 57
Phorbol esters induce intracellular accumulation of the anti-apoptotic protein PED/PEA-15 by preventing ubiquitinylation and proteasomal degradation. 54
PED/PEA-15 regulates glucose-induced insulin secretion by restraining potassium channel expression in pancreatic beta-cells 50
Low Dose Bisphenol-A Regulates Inflammatory Cytokines through GPR30 in Mammary Adipose Cells 47
Glucose regulates insulin mitogenic effect by modulating SHP-2 activation and localization in JAr cells. 46
Glucose-induced expression of the homeotic transcription factor Prep1 is associated with histone post-translational modifications in skeletal muscle 45
Insulin receptor substrate-2 phosphorylation is necessary for protein kinase czeta activation by insulin in l6hir cells. 43
Low-Dose bisphenol-A impairs adipogenesis and generates dysfunctional 3T3-L1 adipocytes 43
Prep1, A Homeodomain transcription factor involved in glucose and lipid metabolism 42
Prep1 deficiency improves metabolic response in white adipose tissue 41
Differential role of insulin receptor substrate (IRS1 and IRS) in L6 skeletal muscle cells expressing the Arg1152Gln insulin receptor. 40
Differential role of insulin receptor substrate (IRS)-1 and IRS-2 in L6 skeletal muscle cells expressing the Arg1152 --> Gln insulin receptor. 40
Abnormal glucose transport and GLUT1 cell-surface content in fibroblasts and skeletal muscle from NIDDM and obese subjects 40
Glucose regulates insulin mitogenic effect by modulating SHP-2 activation and localization in JAr cells 38
A peptide antagonist of Prep1-p160 interaction improves ceramide-induced insulin resistance in skeletal muscle cells 38
miR-214-dependent increase of PHLPP2 levels mediates the impairment of insulin-stimulated akt activation in mouse aortic endothelial cells exposed to methylglyoxal 38
Prep1 regulates angiogenesis through a PGC-1α-mediated mechanism 38
Diagnosis of Flier’s syndrome in a patient with nondiabetic hypoglycemia: a case report and critical appraisal of the literature 37
Insulin induces the interaction of IRS-1 with PKC-alpha and 14-3-3-epsilon 33
In L6 cells, glucose induces cytosolic translocation of PKC alpha, trans-activates the insulin receptor kinase and regulates its own uptake 33
The Relevance of Insulin Action in the Dopaminergic System 33
PED/PEA-15 controls fibroblast motility and wound closure by ERK1/2-dependent mechanisms 32
Insulin-activated protein kinase Cbeta bypasses Ras and stimulates mitogen-activated protein kinase activity and cell proliferation in muscle cells 32
Activation and mitochondrial translocation of protein kinase Cdelta are necessary for insulin stimulation of pyruvate dehydrogenase complex activity in muscle and liver cells 31
Insulin receptor internalization and intracellular sorting are regulated by protein kinase C-zeta and protein kinase b/Akt. 31
Zoonotic Risk of Encephalitozoon cuniculi in Animal-Assisted Interventions: Laboratory Strategies for the Diagnosis of Infections in Humans and Animals 31
Glucose regulates insulin mitogenic effect by modulating SHP-2 activation and localization in JAr cells. 30
In skeletal muscle, advanced glycation end products inhibit insulin action and induce the formation of multimolecular complexes including the receptor for AGEs. 30
Dolichol reverts lovastatin-induced inhibition of insulin action on glycogen synthesis but not on cell cycle regulation, in skeletal muscle and liver cells 30
Bisphenol-A Impairs Insulin Action and Up-Regulates Inflammatory Pathways in Human Subcutaneous Adipocytes and 3T3-L1 Cells. 30
Interleukin 6 reduces vascular smooth muscle cell apoptosis via Prep1 and is associated with aging 30
Autophagy and NLRP3 inflammasome crosstalk in neuroinflammation in aged bovine brains 29
Differential role of IRS-1 and IRS-2 in L6 muscle cells expressing the ARG(1152)-> GLN insulin receptor. 28
Cultured beta cells PED overexpression alters intracellular calcium levels thereby impairing glucose induced insulin secretion 28
Peroxisome Proliferator-Activated Receptor γ activation enhances insulin-stimulated glucose disposal by reducing ped/pea-15 expression in skeletal muscle cells. Evidence for involvement of Activator Protein-1. 28
Insulin-activated PKCb bypasses Ras and stimulates MAPKinase activity and cell proliferation in muscle cells 27
Human glycated albumin affects glucose metabolism in L6 skeletal muscle cells by impairing insulin-induced insulin receptor substrate (IRS) signaling through a protein kinase C alpha-mediated mechanism 27
Thrombin-activated platelets induce proliferation of human skin fibroblasts by stimulating autocrine production of insulin-like growth factor-1 27
Phosphorylation and Signalling of the Insulin Receptor are Controlled by a Basic AminoAcid Motif. 26
Implication of the nlrp3 inflammasome in bovine age‐related sarcopenia 26
In NIH-3T3 fibroblasts, insulin receptor interaction with specific protein kinase C isoforms controls receptor intracellular routing 25
PED/PEA-15 induces autophagy and mediates TGF-beta1 effect on muscle cell differentiation. 24
In NIH-3T3 fibroblasts, insulin receptor interaction with specific protein kinase C isoforms controls receptor intracellular routine. 23
Glucose-transport Is Genetically Altered In Subjects With Type-ii Diabetes (niddm) 23
Low-dose bisphenol-a promotes epigenetic changes at pparγ promoter in adipose precursor cells 23
Anti-skeletal muscle antibodies in sera of dogs with leishmaniasis. 22
Cytokine signature and COVID-19 prediction models in the two waves of pandemics 22
In L6 skeletal muscle cells, glucose induces cytosolic translocation of Protein Kinase C-alfa and trans-activates the insulin receptor kinase. 21
In L6 skeletal muscle tells advanced glycation end products inhibit insulin action by activating src and inducing the formation of a multi-molecular complex 21
Protein kinase Calpha activation by RET: evidence for a negative feedback mechanism controlling RET tyrosine kinase 20
Overproduction of phosphoprotein enriched in diabetes (PED) induces mesangial expansion and upregulates protein kinase C-beta activity and TGF-beta1 expression. 20
Protein kinase Calpha activation by RET: evidence for a negative feedback mechanism controlling RET tyrosine kinase. 19
PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis 19
Protein Kinase B/Akt Binds and Phosphorylates PED/PEA-15, Stabilizing Its Antiapoptotic Action 19
PDK1 interaction with insulin receptor and tyrosine phosphorylation are required for insulin metabolic action. 19
Platelet - Rich Plasma Increases Growth and Motility of Adipose Tissue - Derived Mesenchymal Stem Cells and Controls Adipocyte Secretory Function 19
SARS-CoV-2 Affects Both Humans and Animals: What Is the Potential Transmission Risk? A Literature Review 18
Tyrosine phosphorylation of phosphoinositide-dependent kinase 1 by the insulin receptor is necessary for insulin metabolic signaling 18
Omi/HtrA2 promotes cell death by binding and degrading the anti-apoptotic protein ped/pea-15 18
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Ped/pea-15 regulates glucose-induced insulin secretion by restraining potassium channel expression in pancreatic beta-cells 18
PED/PEA-15 controls TGFbeta production and fibronectin secretion through a PLD/PKCbeta pathway 18
Antagonism between Hepatocyte Nuclear Factor 4 alpha (HNF4 alpha) and Chicken Ovalbumin Upstream Promoter-Transcription Factor 2 (COUP-TFII) modulates Ped/Pea-15 gene expression 18
Protein kinase C-zeta and protein kinase B regulate distinct steps of insulin endocytosis and intracellular sorting 17
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction 17
Thiazolidinediones control the expression of Ped/Pea-15 (phosphoprotein enriched in diabetes) both in vitro and in vivo 17
Thiazolidinediones control the expression of phosphoprotein enriched in diabetes (ped/pea-15) both in vitro and in vivo 17
Insulin stimulates phosphoinositides-dependent kinase (PDK)-1 binding to insulin-receptor C-terminus followed by tyrosine-phosphorylation and activation. 17
PREP1 deficiency downregulates hepatic lipogenesis and attenuates steatohepatitis in mice. 17
Prep1 controls insulin glucoregulatory function in liver by transcriptional targetting of SHP1 tyrosine phosphatase. 17
Receptor-mediated internalization of insulin: potential role of pp120/HA4, a substrate of the insulin receptor kinase 16
Overexpression of the ped/pea-15 gene causes diabetes by impairing glucose-stimulated insulin secretion in addition to insulin action 16
Protein kinase C-alpha regulates insulin action and degradation by interacting with insulin receptor substrate-1 and 14-3-3 epsilon. 16
Thrombin-activated platelets enhance healing of ulcerative skin lesion by inducing IGF-1 release by skin fibroblasts 16
Leishmania spp.-infected dogs have circulating anti-skeletal muscle autoantibodies recognizing serca1 16
The function of PED, a novel gene in type 2 diabetes 15
The PEA15 gene is overexpressed and related to insulin resistance in healthy first-degree relatives of patients with type 2 diabetes 15
Substrate-zymography: a still worthwhile method for gelatinases analysis in biological samples 14
Prep1 deficiency induces protection from diabetes and increased insulin sensitivity through a p160-mediated mechanism. 13
In NIH-3T3 fibroblasts, insulin receptor interaction with specific protein kinase C isoforms controls receptor intracellular routing 13
null 12
The PED/PEA-15 diabetogene as a potential thiazolidinedione target 12
Raised expression of the antiapoptotic protein ped/pea-15 increases susceptibility to chemically induced skin tumor development 12
Mouse models of insulin resistance 11
TGF beta impairs muscle differentiation and induces autophagy by PED/PEA-15-mediated pathway 11
Peroxisome proliferator-activated receptor gamma ligands suppress the transcriptional activation of PED/PEA-15 gene 9
Prep1 Controls Insulin Glucoregulatory Function in Liver by Transcriptional Targetting of SHP1 Tyrosine Phosphatase 9
Platelet-rich plasma counteracts detrimental effect of high-glucose concentrations on mesenchymal stem cells from Bichat fat pad 9
Transforming growth factor-beta increases the expression of PED/PEA-15 and glucose uptake via smad-3 phosphorylation in l6 cells 8
In skeletal muscle cells advanced glycation end products inhibit insulin action by inducing the formation of a multi-molecular complex which includes RAGE, PKCalpha and IRS1 8
Resveratrol Improves Endothelial Function by A PREP1-Mediated Pathway in Mouse Aortic Endothelial Cells 7
The IR1152 mutant insulin receptor selectively impairs insulin action in skeletal muscle but not in liver 4
EVOO Polyphenols Exert Anti-Inflammatory Effects on the Microglia Cell through TREM2 Signaling Pathway 2
Protein kinase C (PKC)-alpha activation inhibits PKC-zeta and mediates the action of PED/PEA-15 on glucose transport in the L6 skeletal muscle cells 1
Totale 2.394
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Categoria #
all - tutte 10.390
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 10.390
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201920 0 0 0 0 0 0 0 0 0 0 0 20
2019/2020238 98 7 11 8 16 2 0 1 7 15 33 40
2020/2021265 19 11 59 15 18 32 60 3 22 2 22 2
2021/2022564 5 0 9 4 12 18 12 16 89 36 145 218
2022/2023591 96 61 25 25 74 74 3 40 87 68 26 12
2023/2024323 12 56 34 26 36 75 6 58 8 10 2 0
Totale 2.394