IRIS
AURICCHIO, ALBERTO
 Distribuzione geografica
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Continente #
AS - Asia 8.500
NA - Nord America 6.355
EU - Europa 4.744
SA - Sud America 1.315
AF - Africa 162
OC - Oceania 17
Continente sconosciuto - Info sul continente non disponibili 5
Totale 21.098
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Nazione #
US - Stati Uniti d'America 6.125
SG - Singapore 4.201
RU - Federazione Russa 2.170
CN - Cina 1.488
VN - Vietnam 1.311
BR - Brasile 1.089
HK - Hong Kong 759
IT - Italia 677
FR - Francia 361
DE - Germania 328
FI - Finlandia 305
UA - Ucraina 295
JP - Giappone 146
GB - Regno Unito 138
NL - Olanda 128
CA - Canada 125
IE - Irlanda 125
IN - India 119
SE - Svezia 95
BD - Bangladesh 93
AR - Argentina 78
MX - Messico 59
IQ - Iraq 56
ZA - Sudafrica 46
EC - Ecuador 45
ID - Indonesia 37
KR - Corea 37
TR - Turchia 37
PK - Pakistan 35
PH - Filippine 34
TH - Thailandia 29
ES - Italia 25
CO - Colombia 24
TW - Taiwan 22
AT - Austria 20
PY - Paraguay 20
PL - Polonia 17
KE - Kenya 16
MA - Marocco 16
VE - Venezuela 16
AU - Australia 14
PE - Perù 13
CL - Cile 12
SA - Arabia Saudita 12
LT - Lituania 11
CI - Costa d'Avorio 10
DZ - Algeria 10
TN - Tunisia 10
UY - Uruguay 10
EG - Egitto 9
NP - Nepal 9
JO - Giordania 8
LB - Libano 8
UZ - Uzbekistan 8
AE - Emirati Arabi Uniti 7
BE - Belgio 7
DO - Repubblica Dominicana 7
JM - Giamaica 7
CR - Costa Rica 6
IR - Iran 6
SN - Senegal 6
KZ - Kazakistan 5
RO - Romania 5
AL - Albania 4
BB - Barbados 4
BO - Bolivia 4
BY - Bielorussia 4
CH - Svizzera 4
CZ - Repubblica Ceca 4
ET - Etiopia 4
IL - Israele 4
ML - Mali 4
AM - Armenia 3
CG - Congo 3
GF - Guiana Francese 3
GT - Guatemala 3
HN - Honduras 3
MY - Malesia 3
OM - Oman 3
PS - Palestinian Territory 3
SO - Somalia 3
AF - Afghanistan, Repubblica islamica di 2
BA - Bosnia-Erzegovina 2
BF - Burkina Faso 2
BG - Bulgaria 2
BM - Bermuda 2
BS - Bahamas 2
CW - ???statistics.table.value.countryCode.CW??? 2
EE - Estonia 2
EU - Europa 2
GA - Gabon 2
HT - Haiti 2
KG - Kirghizistan 2
KH - Cambogia 2
LA - Repubblica Popolare Democratica del Laos 2
LV - Lettonia 2
LY - Libia 2
MK - Macedonia 2
NG - Nigeria 2
NI - Nicaragua 2
Totale 21.048
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Città #
Singapore 1.764
San Jose 1.008
Hong Kong 744
Moscow 573
Chandler 540
Ho Chi Minh City 367
Jacksonville 340
Santa Clara 336
Ashburn 307
Hanoi 293
Millbury 285
Princeton 277
Lauterbourg 272
Nanjing 261
Beijing 260
The Dalles 235
Naples 182
Los Angeles 173
Boston 150
Tokyo 132
São Paulo 127
Buffalo 124
Amsterdam 114
Wilmington 113
Hefei 107
Napoli 92
Nanchang 86
Ottawa 81
New York 73
Redondo Beach 71
Haiphong 53
Des Moines 52
Seattle 49
Norwalk 47
Shenyang 46
Da Nang 45
Frankfurt am Main 44
Munich 44
Hebei 43
Dallas 41
Jiaxing 38
Falls Church 37
Tianjin 36
Rio de Janeiro 35
Orem 33
Belo Horizonte 32
Biên Hòa 32
Chicago 31
Nuremberg 29
Changsha 28
Kunming 28
Can Tho 27
Hải Dương 25
Mexico City 25
Porto Alegre 25
Baghdad 24
Dublin 22
Brasília 21
Brooklyn 21
Dhaka 21
Johannesburg 21
Lawrence 20
Boardman 19
Helsinki 18
San Francisco 18
Seoul 18
Toronto 18
Denver 17
Guayaquil 17
Hangzhou 17
Changchun 16
Guangzhou 16
Poplar 15
Siena 15
Atlanta 14
Chennai 14
Lahore 14
Quito 14
Rome 14
Salvador 14
Woodbridge 14
Campinas 13
Curitiba 13
Nairobi 13
New Delhi 13
Ninh Bình 13
Warsaw 13
Kronberg 12
Thái Bình 12
Thái Nguyên 12
Caserta 11
Falkenstein 11
Fortaleza 11
Manaus 11
Manchester 11
Montreal 11
Turku 11
Bangkok 10
Buenos Aires 10
Council Bluffs 10
Totale 11.085
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Nome #
Light-responsive microRNA miR-211 targets Ezrin to modulate lysosomal biogenesis and retinal cell clearance 180
A single-step affinity column for purification of serotype 5-based adeno-associated viral vectors. 172
Autonomic dysfunction in children with Hirschsprung's disease. 156
Constitutive and regulated expression of processed insulin following in vivo hepatic gene transfer. 150
Endothelin-B receptor mutations in patients with isolated Hirschsprung disease from a non inbred population. 149
Inhibition of lipofuscin aggregation by molecular tweezers 147
Adeno-associated viral vectors for retinal gene transfer. 140
GENE THERAPY FOR LEBER'S CONGENITAL AMAUROSIS IS SAFE AND EFFECTIVE 1.5 YEARS AFTER VECTOR ADMINISTRATION 131
Intein-mediated protein trans-splicing expands adeno-associated virus transfer capacity in the retina 130
MicroRNAs involved in molecular circuitries relevant for the duchenne muscular dystrophy pathogenesis are controlled by the dystrophin/nNOS pathway 123
Has retinal gene therapy come of age? From bench to bedside and back to bench 123
A comprehensive map of CNS transduction by eight recombinant adeno-associated virus serotypes upon cerebrospinal fluid administration in pigs 120
Single systemic transfer of a human gene associated with exceptional longevity halts the progression of atherosclerosis and inflammation in ApoE knockout mice through a CXCR4-mediated mechanism 119
Improved dual AAV vectors with reduced expression of truncated proteins are safe and effective in the retina of a mouse model of Stargardt disease 116
Systemic but not intraocular Epo gene transfer protects the retina from light- and genetic-induced degeneration. 115
Safe and effective liver-directed AAV-mediated homology-independent targeted integration in mouse models of inherited diseases 113
Seeing the Light after 25 Years of Retinal Gene Therapy 113
Endothelin-B receptor mutations in patients with isolated Hirschsprung disease from a non-inbred population. 112
Liver-Directed Adeno-Associated Virus–Mediated Gene Therapy for Mucopolysaccharidosis Type VI 112
Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration. 111
Multi-year enzyme expression in patients with mucopolysaccharidosis type VI after liver-directed gene therapy 110
AAV vectors efficiently and stably transduce fetal retina. 109
Disease rescue and increased lifespan in a model of cardiomyopathy and muscular dystrophy by combined AAV treatments. 109
Gene therapy of inherited retinal degenerations: prospects and challenges. 109
Pharmacologically-regulated gene expression in the retina following transduction with viral vectors. 108
AP20817-inducible activation of chimeric insulin receptor mimics insulin action in hepatocytes transduced with AAV 108
Effective delivery of large genes by dual vectors 108
AP20187-mediated activation of a chimeric insulin receptor results in insulin-like actions in skeletal muscle and liver of diabetic mice 107
Inclusion of a degron reduces levelsof undesired inteins after AAV-mediated proteintrans-splicing in the retina 107
Full-length ATP7B reconstituted through protein trans-splicing corrects Wilson disease in mice 106
Intramuscular viral delivery of paraplegin rescues peripheral axonopathy in a model of hereditary spastic paraplegia. 106
Constitutive and AP20187-induced ret activation in photoreceptors does not protect from light-induced damage 106
ASSOCIATION BETWEEN GENOTYPE AND DISEASE PROGRESSION IN ITALIAN STARGARDT PATIENTS: A Retrospective Natural History Study 106
Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport. 105
Filamin A is mutated in X-linked chronic idiopathic intestinal pseudo-obstruction with central nervous system involvement. 105
TOWARDS CLINICAL TRIALS FOR AAV-MEDIATED EYE- AND LIVER - DIRECT GENE THERAPY TRANSLATION AAV 105
Triple Vectors Expand AAV Transfer Capacity in the Retina 105
Current Status on Clinical Development of Adeno-Associated Virus-Mediated Liver-Directed Gene Therapy for Inborn Errors of Metabolism 105
Therapeutic homology-independent targeted integration in retina and liver 105
AAV-mediated gene transfer for retinal diseases 101
Double heterozygosity for a RET substitution interfering with splicing and an EDNRB missense mutation in Hirschsprung disease. 99
Delivery of adeno-associated virus vectors to the fetal retina: impact of viral capsid proteins on retinal neuronal progenitor transduction. 99
Effective delivery of large genes to the retina by dual AAV vectors. 98
Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial. 98
Treatment of bone growth disorders 98
Multiple vector system and uses thereof. 98
Autonomic dysfunction in children with Hirschsprung's disease 97
Sustained Reduction of Hyperbilirubinemia in Gunn Rats after Adeno-Associated Virus-Mediated Gene Transfer of Bilirubin UDP-Glucuronosyltransferase Isozyme 1A1 to Skeletal Muscle. 97
Efficacy of a combined intracerebral and systemic gene delivery approach for the treatment of a severe lysosomal storage disorder. 97
Efficient gene delivery to the cone-enriched pig retina by dual AAV vectors. 96
AAV-mediated Tyrosinase Gene Transfer Restores Melanogenesis and Retinal Function in a Model of Oculo-cutaneous Albinism Type I (OCA1). 95
Exchange of surface proteins impacts on viral vector cellular specificity and transduction characteristics: the retina as a model. 94
Gene therapy for Crigler-Najjar syndrome 94
Low-dose Gene Therapy Reduces the Frequency of Enzyme Replacement Therapy in a Mouse Model of Lysosomal Storage Disease 94
High-Throughput Screening Identifies Kinase Inhibitors That Increase Dual Adeno-Associated Viral Vector Transduction in Vitro and in Mouse Retina 93
Identification and biochemical characterization of novel putative substrates for the Epidermal Growth Factor Receptor kinase. 92
Gene Therapy of ABCA4-Associated Diseases. 92
Large gene delivery to the retina with AAV vectors: are we there yet? 92
Microphthalmia transcription factor controls expression of the Ocular albinism type 1 gene. 90
Vector platforms for gene therapy of inherited retinopathies. 90
Amelioration of both functional and morphological abnormalities in the retina of a mouse model of ocular albinism following AAV-mediated gene transfer. 90
Hybrid vectors based on adeno-associated virus serotype 2 and 5 for muscle directed gene transfer. 89
Efficient trans-splicing in the retina expands the utility of adeno-associated virus as a vector for gene therapy. 89
Aberrant splicing in the ocular albinism type 1 gene (OA1/GPR143) is corrected in vitro by morpholino antisense oligonucleotides. 89
Allele-specific editing ameliorates dominant retinitis pigmentosa in a transgenic mouse model 89
Inhibition of ocular neovascularization by Hedgehog blockade. 88
An in vivo doxycycline-controlled expression system for functional studies of the retina. 87
Combined rod and cone transduction by AAV2/8. 87
Novel adeno-associated virus serotypes efficiently transduce murine photoreceptors. 87
Correlation betwen photoreceptor layer integrity and visual function in patients with Stargardt Disease:implication for gene therapy 85
Postoperative detection of circulating tumor cells predicts tumor recurrence in colorectal cancer patients 85
Correction of Hunter syndrome via gene delivery using the MPSII mouse model. 84
Safety and efficacy of gene transfer for Leber's congenital amaurosis. 83
Analisi delle velocitá istantanee di assottigliamento della parete posteriore in atleti di resistenza. 82
Pharmacological regulation of the insulin receptor signaling mimics insulin action in cells transduced with viral vectors. 82
gene therapy of human inherited diseases 82
Effect of over-expression of Pigment Epithelium-Derived Factor (PEDF) on developing retinal vasculature in the mouse. 81
In vivo doxycycline controlled regulated system in photoreceptor cells. 81
A strategy for Oa1 gene transfer using AAV vectors 81
Evaluation of italian patients with Leber Congenital Amaurosis due to AIPL1 mutations highlights the potential applicability of gene therapy 81
Methods and composition for treatment of obesity 81
AAV vectors for gene tranfer to the adult retina 79
AAV-mediated photoreceptor transduction of the pig cone-enriched retina 79
CLINICAL PRESENTATION AND DISEASE COURSE OF USHER SYNDROME BECAUSE OF MUTATIONS IN MYO7A OR USH2A 79
Inhibition of Lipofuscin Aggregation by Molecular Tweezers. 79
Functional correction of CNS lesions in an MPS-IIIA mouse model by intracerebral AAV-mediated delivery of sulfamidase and SUMF1 genes. 78
AAV vectors for in vivo gene transfer 76
Recombinant vectors based on porcine adeno-associated viral serotypes transduce the murine and pig retina. 76
The locus for a novel syndromic form of neuronal intestinal pseudoobstruction maps to Xq28. 75
Versatility of AAV vectors for retinal gene transfer 75
Method for purification of viral vectors having proteins which bind sialic acid 75
Composition and methods useful for non-invasive delivery therapeutic molecules to the bloodstream. 75
Evaluation of ocular gene therapy in an italian patient affected by congenital leber amaurosis type 2 treated in both eyes 75
The European Society of Gene and Cell Therapy: A Nearly 30-Year Endeavor to Make Gene Therapy a Clinical Reality 75
Retinal gene therapy for Stargardt disease with dual AAV intein vectors is both safe and effective in large animal models 74
Systemic but not intraocular Epo gene transfer protects the retina from light-and genetic-induced degeneration. 74
Double heterozigosity for a RET substitution interfering with splicing and an EDNRB missense mutation in Hirschsprung disease. 72
Aetiology and assessment of constipation in children 72
AP20187-Inducible activation of a chimeric insulin receptor mimics insulin action in hepatocytes transduced with AAV. 71
Aetiology and assessment of constipation in children, in: Chronic constipation. Ed: Barbara, L. Corinaldesi, R. Gizzi, G. Stanghellini, V. Pub: W.B. Saunders Company Ltd 71
Totale 9.878
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Categoria #
all - tutte 70.111
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 70.111
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202110 0 0 0 0 0 0 0 0 0 0 0 10
2021/20221.076 13 2 2 23 11 36 22 54 121 32 129 631
2022/20231.325 303 116 36 94 146 142 27 113 182 97 56 13
2023/2024832 31 134 144 45 21 33 34 25 4 6 259 96
2024/20256.003 386 700 13 10 151 244 623 320 766 608 1.590 592
2025/20269.690 1.229 959 875 769 1.628 362 973 803 1.413 484 192 3
Totale 21.305