Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study

Moss, Davina J Hensman;Tabrizi, Sarah J;Mead, Simon;Lo, Kitty;Pardiñas, Antonio F;Holmans, Peter;Jones, Lesley;Langbehn, Douglas;Coleman, A.;Santos, R Dar;Decolongon, J.;Sturrock, A.;Bardinet, E.;Ret, C Jauff;Justo, D.;Lehericy, S.;Marelli, C.;Nigaud, K.;Valabrègue, R.;van den Bogaard, S. J. A.;Dumas, E. M.;van der Grond, J.;t'Hart, E. P.;Jurgens, C.;Witjes-Ane, M. -N.;Arran, N.;Callaghan, J.;Stopford, C.;Frost, C.;Jones, R.;Hobbs, N.;Lahiri, N.;Ordidge, R.;Owen, G.;Pepple, T.;Read, J.;Say, M.;Wild, E.;Patel, A.;Fox, N. C.;Gibbard, C.;Malone, I.;Crawford, H.;Whitehead, D.;Keenan, S.;Cash, D. M.;Berna, C.;Bechtel, N.;Bohlen, S.;Man, A Hoff;Kraus, P.;Axelson, E.;Wang, C.;Acharya, T.;Lee, S.;Monaco, W.;Campbell, C.;Queller, S.;Whitlock, K.;Campbell, C.;Campbell, M.;Frajman, E.;Milchman, C.;O'Regan, A.;Labuschagne, I.;Stout, J.;Landwehrmeyer, B.;Craufurd, D.;Scahill, R.;Hicks, S.;Kennard, C.;Johnson, H.;Tobin, A.;Rosas, H. D.;Reilmann, R.;Borowsky, B.;Pourchot, C.;Andrews, S. C.;Bachoud-Lévi, Anne-Catherine;Bentivoglio, Anna Rita;Biunno, Ida;Bonelli, Raphael;Burgunder, Jean-Marc;Dunnett, Stephen;Ferreira, Joaquim;Handley, Olivia;Heiberg, Arvid;Illmann, Torsten;Landwehrmeyer, G. Bernhard;Levey, Jamie;Ramos-Arroyo, Maria A.;Nielsen, Jørgen;Koivisto, Susana Pro;Päivärinta, Markku;Roos, Raymund A. C.;Sebastián, A Rojo;Tabrizi, Sarah;Vandenberghe, Wim;Verellen-Dumoulin, Christine;Uhrova, Tereza;Wahlström, Jan;Zaremba, Jacek;Baake, Verena;Barth, Katrin;Garde, Monica Bascuñana;Betz, Sabrina;Bos, Reineke;Callaghan, Jenny;Come, Adrien;Guedes, Leonor Correia;Ecker, Daniel;Finisterra, Ana Maria;Fullam, Ruth;Gilling, Mette;Gustafsson, Lena;Handley, Olivia J;Hvalstedt, Carina;Held, Christine;Koppers, Kerstin;Lamanna, Claudia;Laurà, Matilde;Descals, Asunción Martínez;Martinez-Horta, Saül;Mestre, Tiago;Minster, Sara;Monza, Daniela;Mütze, Lisanne;Oehmen, Martin;Orth, Michael;Padieu, Hélène;Paterski, Laurent;Peppa, Nadia;Koivisto, Susana Pro;Di Renzo, Martina;Rialland, Amandine;Røren, Niini;Šašinková, Pavla;Timewell, Erika;Townhill, Jenny;Cubillo, Patricia Trigo;da Silva, Wildson Vieira;van Walsem, Marleen R;Whalstedt, Carina;Witjes-Ané, Marie-Noelle;Witkowski, Grzegorz;Wright, Abigail;Zielonka, Daniel;Zielonka, Eugeniusz;Zinzi, Paola;Bonelli, Raphael M.;Lilek, Sabine;Hecht, Karen;Herranhof, Brigitte;Holl, Anna;Kapfhammer, Hans-Peter;Koppitz, Michael;Magnet, Markus;Müller, Nicole;Otti, Daniela;Painold, Annamaria;Reisinger, Karin;Scheibl, Monika;Schöggl, Helmut;Ullah, Jasmin;Braunwarth, Eva-Maria;Brugger, Florian;Buratti, Lisa;Hametner, Eva-Maria;Hepperger, Caroline;Holas, Christiane;Hotter, Anna;Hussl, Anna;Müller, Christoph;Poewe, Werner;Seppi, Klaus;Sprenger, Fabienne;Wenning, Gregor;Boogaerts, Andrea;Calmeyn, Godelinde;Delvaux, Isabelle;Liessens, Dirk;Somers, Nele;Dupuit, Michel;Minet, Cécile;van Paemel, Dominique;Ribaï, Pascale;Verellen-Dumoulin, Christine;Boogaerts, Andrea;Vandenberghe, Wim;van Reijen, Dimphna;Klempír, Jirí;Majerová, Veronika;Roth, Jan;Stárková, Irena;Hjermind, Lena E.;Jacobsen, Oda;Nielsen, Jørgen E.;Larsen, Ida Unmack;Vinther-Jensen, Tua;Hiivola, Heli;Hyppönen, Hannele;Martikainen, Kirsti;Tuuha, Katri;Allain, Philippe;Bonneau, Dominique;Bost, Marie;Gohier, Bénédicte;Guérid, Marie-Anne;Olivier, Audrey;Prundean, Adriana;Scherer-Gagou, Clarisse;Verny, Christophe;Babiloni, Blandine;Debruxelles, Sabrina;Duché, Charlotte;Goizet, Cyril;Jameau, Laetitia;Lafoucrière, Danielle;Spampinato, Umberto;Barthélémy, Rekha;De Bruycker, Christelle;Carette, Maryline Cabaret Anne-Sophie;Defebvre, Eric Decorte Luc;Delliaux, Marie;Delval, Arnaud;Destee, Alain;Dujardin, Kathy;Lemaire, Marie-Hélène;Manouvrier, Sylvie;Peter, Mireille;Plomhouse, Lucie;Sablonnière, Bernard;Simonin, Clémence;Thibault-Tanchou, Stéphanie;Vuillaume, Isabelle;Bellonet, Marcellin;Berrissoul, Hassan;Blin, Stéphanie;Courtin, Françoise;Duru, Cécile;Fasquel, Véronique;Godefroy, Olivier;Krystkowiak, Pierre;Mantaux, Béatrice;Roussel, Martine;Wannepain, Sandrine;Azulay, Jean-Philippe;Delfini, Marie;Eusebio, Alexandre;Fluchere, Frédérique;Mundler, Laura;Anheim, Mathieu;Julié, Celine;Boukbiza, Ouhaid Lagha;Longato, Nadine;Rudolf, Gabrielle;Tranchant, Christine;Zimmermann, Marie-Agathe;Kosinski, Christoph Michael;Milkereit, Eva;Probst, Daniela;Reetz, Kathrin;Sass, Christian;Schiefer, Johannes;Schlangen, Christiane;Werner, Cornelius J.;Gelderblom, Harald;Priller, Josef;Prüß, Harald;Spruth, Eike Jakob;Ellrichmann, Gisa;Herrmann, Lennard;Hoffmann, Rainer;Kaminski, Barbara;Kotz, Peter;Prehn, Christian;Saft, Carsten;Lange, Herwig;Maiwald, Robert;Löhle, Matthias;Maass, Antonia;Schmidt, Simone;Bosredon, Cecile;Storch, Alexander;Wolz, Annett;Wolz, Martin;Capetian, Philipp;Lambeck, Johann;Zucker, Birgit;Boelmans, Kai;Ganos, Christos;Heinicke, Walburgis;Hidding, Ute;Lewerenz, Jan;Münchau, Alexander;Orth, Michael;Schmalfeld, Jenny;Stubbe, Lars;Zittel, Simone;Diercks, Gabriele;Dressler, Dirk;Gorzolla, Heike;Schrader, Christoph;Tacik, Pawel;Ribbat, Michael;Longinus, Bernhard;Bürk, Katrin;Möller, Jens Carsten;Rissling, Ida;Mühlau, Mark;Peinemann, Alexander;Städtler, Michael;Weindl, Adolf;Winkelmann, Juliane;Ziegler, Cornelia;Bechtel, Natalie;Beckmann, Heike;Bohlen, Stefan;Hölzner, Eva;Lange, Herwig;Reilmann, Ralf;Rohm, Stefanie;Rumpf, Silke;Schepers, Sigrun;Weber, Natalia;Dose, Matthias;Leythäuser, Gabriele;Marquard, Ralf;Raab, Tina;Wiedemann, Alexandra;Barth, Katrin;Buck, Andrea;Connemann, Julia;Ecker, Daniel;Geitner, Carolin;Held, Christine;Kesse, Andrea;Landwehrmeyer, Bernhard;Lang, Christina;Lewerenz, Jan;Lezius, Franziska;Nepper, Solveig;Niess, Anke;Orth, Michael;Schneider, Ariane;Schwenk, Daniela;Süßmuth, Sigurd;Trautmann, Sonja;Weydt, Patrick;Cormio, Claudia;Sciruicchio, Vittorio;Serpino, Claudia;de Tommaso, Marina;Capellari, Sabina;Cortelli, Pietro;Galassi, Roberto;Rizzo, Giovanni;Poda, Roberto;Scaglione, Cesa;Bertini, Elisabetta;Ghelli, Elena;Ginestroni, Andrea;Massaro, Francesca;Mechi, Claudia;Paganini, Marco;Piacentini, Silvia;Pradella, Silvia;Romoli, Anna Maria;Sorbi, Sandro;Abbruzzese, Giovanni;di Poggio, Monica Bandettini;Ferrandes, Giovanna;Mandich, Paola;Marchese, Roberta;Albanese, Alberto;Di Bella, Daniela;Castaldo, Anna;Di Donato, Stefano;Gellera, Cinzia;Genitrini, Silvia;Mariotti, Caterina;Monza, Daniela;Nanetti, Lorenzo;Paridi, Dominga;Soliveri, Paola;Tomasello, Chiara;De Michele, Giuseppe;DI MAIO, LUIGI;Massarelli, Marco;Peluso, Silvio;Roca, Alessandro;Russo, Cinzia Valeria;Salvatore, Elena;Sorrentino, Pierpaolo;Amico, Enrico;Favellato, Mariagrazia;Griguoli, Annamaria;Mazzante, Irene;Petrollini, Martina;Squitieri, Ferdinando;D'Alessio, Barbara;Esposito, Chiara;Bentivoglio, Rita;Frontali, Marina;Guidubaldi, Arianna;Ialongo, Tamara;Jacopini, Gioia;Piano, Carla;Romano, Silvia;Soleti, Francesco;Spadaro, Maria;Zinzi, Paola;van Hout, Monique S. E.;Verhoeven, Marloes E.;van Vugt, Jeroen P. P.;de Weert, A. Marit;Bolwijn, J. J. W.;Dekker, M.;Kremer, B.;Leenders, K. L.;van Oostrom, J. C. H.;van den Bogaard, Simon J. A.;Bos, Reineke;Dumas, Eve M.;’t Hart, Ellen P.;Roos, Raymund A. C.;Kremer, Berry;Verstappen, C. C. P.;Aaserud, Olaf;Jan Frich, C.;Heiberg, Arvid;van Walsem, Marleen R;Wehus, Ragnhild;Bjørgo, Kathrine;Fannemel, Madeleine;Gørvell, Per F.;Lorentzen, Eirin;Koivisto, Susana Pro;Retterstøl, Lars;Stokke, Bodil;Bjørnevoll, Inga;Sando, Sigrid Botne;Dziadkiewicz, Artur;Nowak, Malgorzata;Robowski, Piotr;Sitek, Emilia;Slawek, Jaroslaw;Soltan, Witold;Szinwelski, Michal;Blaszcyk, Magdalena;Boczarska-Jedynak, Magdalena;Ciach-Wysocka, Ewelina;Gorzkowska, Agnieszka;Jasinska-Myga, Barbara;Klodowska-Duda, Gabriela;Opala, Gregorz;Stompel, Daniel;Banaszkiewicz, Krzysztof;Bocwinska, Dorota;Bojakowska-Jaremek, Kamila;Dec, Malgorzata;Krawczyk, Malgorzata;Rudzinska, Monika;Szczygiel, Elzbieta;Szczudlik, Andrzej;Wasielewska, Anna;Wójcik, Magdalena;Bryl, Anna;Ciesielska, Anna;Klimberg, Aneta;Marcinkowski, Jerzy;Samara, Husam;Sempolowicz, Justyna;Zielonka, Daniel;Gogol, Anna;Janik, Piotr;Kwiecinski, Hubert;Jamrozik, Zygmunt;Antczak, Jakub;Jachinska, Katarzyna;Krysa, Wioletta;Rakowicz, Maryla;Richter, Przemyslaw;Rola, Rafal;Ryglewicz, Danuta;Sienkiewicz-Jarosz, Halina;Stepniak, Iwona;Sulek, Anna;Witkowski, Grzegorz;Zaremba, Jacek;Zdzienicka, Elzbieta;Zieora-Jakutowicz, Karolina;Ferreira, Joaquim J;Coelho, Miguel;Guedes, Leonor Correia;Mendes, Tiago;Mestre, Tiago;Valadas, Anabela;Andrade, Carlos;Gago, Miguel;Garrett, Carolina;Guerra, Maria Rosália;Herrera, Carmen Durán;Garcia, Patrocinio Moreno;Barbera, Miquel Aguilar;Guia, Dolors Badenes;Hernanz, Laura Casas;Catena, Judit López;Ferrer, Pilar Quiléz;Sebastián, Ana Rojo;Carruesco, Gemma Tome;Bas, Jordi;Busquets, Núria;Calopa, Matilde;Robert, Misericordia Floriach;Viladrich, Celia Mareca;Idiago, Jesús Miguel Ruiz;Riballo, Antonio Villa;Cubo, Esther;Polo, Cecilia Gil;Mariscal, Natividad;Rivadeneyra, Perez Jessica;Barrero, Francisco;Morales, Blas;Fenollar, María;García, Rocío García-Ramos;Ortega, Paloma;Villanueva, Clara;Alegre, Javier;Bascuñana, Mónica;Caldentey, Juan Garcia;Ventura, Marta Fatás;Ribas, Guillermo García;de Yébenes, Justo García;Moreno, José Luis López-Sendón;Cubillo, Patricia Trigo;Alegre, Javier;Frech, Fernando Alonso;de Yébenes, Justo García;Ruíz, Pedro J García;Martínez-Descals, Asunción;Guerrero, Rosa;Artiga, María José Saiz;Sánchez, Vicenta;Perea, María Fuensanta Noguera;Fortuna, Lorenza;Manzanares, Salvadora;Reinante, Gema;Torres, María Martirio Antequera;Moreau, Laura Vivancos;González González, Sonia;Guisasola, Luis Menéndez;Salvador, Carlos;Martín, Esther Suaréz San;Ramirez, Inés Legarda;Gorospe, Aranzazú;Lopera, Mónica Rodriguez;Arques, Penelope Navas;Rodríguez, María José Torres;Pastor, Barbara Vives;Gaston, Itziar;Martinez-Jaurrieta, Maria Dolores;Ramos-Arroyo, Maria A.;Moreno, Jose Manuel Garcia;Lucena, Carolina Mendez;Damas, Fatima;Cortegana, Hermoso Eva Pacheco;Peña, José Chacón;Redondo, Luis;Carrillo, Fátima;Teresa Cáceres, María;Mir, Pablo;Suarez, María José Lama;Vargas-González, Laura;Bosca, Maria E.;Brugada, Francisco Castera;Burguera, Juan Andres;Campos, Anabel;Vilaplana, Garcia Carmen Peiró;Berglund, Peter;Constantinescu, Radu;Fredlund, Gunnel;Høsterey-Ugander, Ulrika;Linnsand, Petra;Neleborn-Lingefjärd, Liselotte;Wahlström, Jan;Wentzel, Magnus;Loutfi, Ghada;Olofsson, Carina;Stattin, Eva-Lena;Westman, Laila;Wikström, Birgitta;Burgunder, Jean-Marc;Stebler, Yanik;Kaelin, Alain;Romero, Irene;Schüpbach, Michael;Weber Zaugg, Sabine;Hauer, Maria;Gonzenbach, Roman;Jung, Hans H.;Mihaylova, Violeta;Petersen, Jens;Jack, Roisin;Matheson, Kirsty;Miedzybrodzka, Zosia;Rae, Daniela;Simpson, Sheila A;Summers, Fiona;Ure, Alexandra;Vaughan, Vivien;Akhtar, Shahbana;Crooks, Jenny;Curtis, Adrienne;de Souza, Jenny;Piedad, John;Rickards, Hugh;Wright, Jan;Coulthard, Elizabeth;Gethin, Louise;Hayward, Beverley;Sieradzan, Kasia;Wright, Abigail;Armstrong, Matthew;Barker, Roger A.;O'Keefe, Deidre;Di Pietro, Anna;Fisher, Kate;Goodman, Anna;Hill, Susan;Kershaw, Ann;Mason, Sarah;Paterson, Nicole;Raymond, Lucy;Swain, Rachel;Guzman, Natalie Valle;Busse, Monica;Butcher, Cynthia;Callaghan, Jenny;Dunnett, Stephen;Clenaghan, Catherine;Fullam, Ruth;Handley, Olivia;Hunt, Sarah;Jones, Lesley;Jones, Una;Khalil, Hanan;Minster, Sara;Owen, Michael;Price, Kathleen;Rosser, Anne;Townhill, Jenny;Edwards, Maureen;Ho, Carrie;Hughes, Teresa;McGill, Marie;Pearson, Pauline;Porteous, Mary;Smith, Paul;Brockie, Peter;Foster, Jillian;Johns, Nicola;McKenzie, Sue;Rothery, Jean;Thomas, Gareth;Yates, Shona;Burrows, Liz;Chu, Carol;Fletcher, Amy;Gallantrae, Deena;Hamer, Stephanie;Harding, Alison;Klöppel, Stefan;Kraus, Alison;Laver, Fiona;Lewis, Monica;Longthorpe, Mandy;Markova, Ivana;Raman, Ashok;Robertson, Nicola;Silva, Mark;Thomson, Aileen;Wild, Sue;Yardumian, Pam;Chu, Carol;Evans, Carole;Gallentrae, Deena;Hamer, Stephanie;Kraus, Alison;Markova, Ivana;Raman, Ashok;Chu, Carol;Hamer, Stephanie;Hobson, Emma;Jamieson, Stuart;Kraus, Alison;Markova, Ivana;Raman, Ashok;Musgrave, Hannah;Rowett, Liz;Toscano, Jean;Wild, Sue;Yardumian, Pam;Bourne, Colin;Clapton, Jackie;Clayton, Carole;Dipple, Heather;Freire-Patino, Dawn;Grant, Janet;Gross, Diana;Hallam, Caroline;Middleton, Julia;Murch, Ann;Thompson, Catherine;Alusi, Sundus;Davies, Rhys;Foy, Kevin;Gerrans, Emily;Pate, Louise;Andrews, Thomasin;Dougherty, Andrew;Golding, Charlotte;Kavalier, Fred;Laing, Hana;Lashwood, Alison;Robertson, Dene;Ruddy, Deborah;Santhouse, Alastair;Whaite, Anna;Andrews, Thomasin;Bruno, Stefania;Doherty, Karen;Golding, Charlotte;Haider, Salman;Hensman, Davina;Lahiri, Nayana;Lewis, Monica;Novak, Marianne;Patel, Aakta;Robertson, Nicola;Rosser, Elisabeth;Tabrizi, Sarah;Taylor, Rachel;Warner, Thomas;Wild, Edward;Arran, Natalie;Bek, Judith;Callaghan, Jenny;Craufurd, David;Fullam, Ruth;Hare, Marianne;Howard, Liz;Huson, Susan;Johnson, Liz;Jones, Mary;Murphy, Helen;Oughton, Emma;Partington-Jones, Lucy;Rogers, Dawn;Sollom, Andrea;Snowden, Julie;Stopford, Cheryl;Thompson, Jennifer;Trender-Gerhard, Iris;Verstraelen, Nichola;Westmoreland, Leann;Armstrong, Richard;Dixon, Kathryn;Nemeth, Andrea H;Siuda, Gill;Valentine, Ruth;Harrison, David;Hughes, Max;Parkinson, Andrew;Soltysiak, Beverley;Bandmann, Oliver;Bradbury, Alyson;Gill, Paul;Fairtlough, Helen;Fillingham, Kay;Foustanos, Isabella;Kazoka, Mbombe;O'Donovan, Kirsty;Peppa, Nadia;Taylor, Cat;Tidswell, Katherine;Quarrell, Oliver;Burgunder, Jean-Marc;Lau, Puay Ngoh;Pica, Emmanul;Tan, Louis

2017