Autism spectrum disorders (ASD) are neurodevelopmental disorders without a definitive etiology in most cases. Environmental factors, such as viral infections, have been linked with anomalies in brain growth, neuronal development, and functional connectivity. Congenital cytomegalovirus (CMV) infection has been associated with the onset of ASD in several case reports. The aim of this study was to evaluate the prevalence of congenital CMV infection in children with ASD and in healthy controls.
Prevalence of Congenital Cytomegalovirus Infection Assessed Through Viral Genome Detection in Dried Blood Spots in Children with Autism Spectrum Disorders / Gentile, Ivan; Zappulo, Emanuela; Riccio, Maria Pia; Binda, Sandro; Bubba, Laura; Pellegrinelli, Laura; Scognamiglio, Domenico; Operto, Francesca; Margari, Lucia; Borgia, Guglielmo; Bravaccio, Carmela. - In: IN VIVO. - ISSN 0258-851X. - 31:3(2017), pp. 467-473-473. [10.21873/invivo.11085]
Prevalence of Congenital Cytomegalovirus Infection Assessed Through Viral Genome Detection in Dried Blood Spots in Children with Autism Spectrum Disorders
GENTILE, Ivan;ZAPPULO, EMANUELA;BORGIA, GUGLIELMO;BRAVACCIO, CARMELA
2017
Abstract
Autism spectrum disorders (ASD) are neurodevelopmental disorders without a definitive etiology in most cases. Environmental factors, such as viral infections, have been linked with anomalies in brain growth, neuronal development, and functional connectivity. Congenital cytomegalovirus (CMV) infection has been associated with the onset of ASD in several case reports. The aim of this study was to evaluate the prevalence of congenital CMV infection in children with ASD and in healthy controls.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
