Angiotensin converting enzyme (ACE)-inhibitors decrease glomerular hyperfiltration but not microalbuminuria and proteinuria in glycogen storage disease type I. In the current study, we demonstrated that severe hyperlipidemia is associated with ACE-inhibitor ineffectiveness. We underline the importance of adequate metabolic control in glycogen storage disease type I. A combination therapy with ACE-inhibitors and lipid lowering drugs might be considered.

Progression of renal damage in glycogen storage disease type I is associated to hyperlipidemia: a multicenter prospective Italian study / Melis, Daniela; Cozzolino, Mariarosaria; Minopoli, Giorgia; Balivo, Francesca; Parini, Rossella; Rigoldi, Miriam; Paci, Sabrina; Dionisi Vici, Carlo; Burlina, Alberto; Andria, Generoso; Parenti, Giancarlo. - In: THE JOURNAL OF PEDIATRICS. - ISSN 0022-3476. - 166:4(2015), pp. 1079-1082. [10.1016/j.jpeds.2014.12.015]

Progression of renal damage in glycogen storage disease type I is associated to hyperlipidemia: a multicenter prospective Italian study

MELIS, DANIELA;COZZOLINO, MARIAROSARIA;BALIVO, FRANCESCA;Parini, Rossella;ANDRIA, GENEROSO;PARENTI, GIANCARLO
2015

Abstract

Angiotensin converting enzyme (ACE)-inhibitors decrease glomerular hyperfiltration but not microalbuminuria and proteinuria in glycogen storage disease type I. In the current study, we demonstrated that severe hyperlipidemia is associated with ACE-inhibitor ineffectiveness. We underline the importance of adequate metabolic control in glycogen storage disease type I. A combination therapy with ACE-inhibitors and lipid lowering drugs might be considered.
2015
Progression of renal damage in glycogen storage disease type I is associated to hyperlipidemia: a multicenter prospective Italian study / Melis, Daniela; Cozzolino, Mariarosaria; Minopoli, Giorgia; Balivo, Francesca; Parini, Rossella; Rigoldi, Miriam; Paci, Sabrina; Dionisi Vici, Carlo; Burlina, Alberto; Andria, Generoso; Parenti, Giancarlo. - In: THE JOURNAL OF PEDIATRICS. - ISSN 0022-3476. - 166:4(2015), pp. 1079-1082. [10.1016/j.jpeds.2014.12.015]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/672645
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