We investigated the serum fatty acid profiles of cholesterol esters, phospholipids and triglycerides in 24 patients with Friedreich's disease and 16 patients with other forms of spinocerebellar degeneration. In 8 patients with Friedreich's disease we also analyzed the fatty acid profile of the lipoprotein fractions. We found no major differences in fatty acid profiles between ataxic patients and sex and age-matched controls; in particular there was no decrease of linoleic acid in Friedreich's disease. The level of linoleic acid in serum cholesterol esters decreased with increasing disability of patients.
Serum lipoprotein fatty acid profile in hereditary ataxias / Iorio, L.; DE MICHELE, Giuseppe; Filla, Alessandro; Martino, L. D.; Postiglione, A.; Patti, L.; Campanella, G.. - In: CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES. - ISSN 0317-1671. - ELETTRONICO. - 20:(1993), pp. 206-209.
Serum lipoprotein fatty acid profile in hereditary ataxias.
DE MICHELE, GIUSEPPE;FILLA, ALESSANDRO;A. Postiglione;
1993
Abstract
We investigated the serum fatty acid profiles of cholesterol esters, phospholipids and triglycerides in 24 patients with Friedreich's disease and 16 patients with other forms of spinocerebellar degeneration. In 8 patients with Friedreich's disease we also analyzed the fatty acid profile of the lipoprotein fractions. We found no major differences in fatty acid profiles between ataxic patients and sex and age-matched controls; in particular there was no decrease of linoleic acid in Friedreich's disease. The level of linoleic acid in serum cholesterol esters decreased with increasing disability of patients.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
