The lay press often heralds polyphenols as panacea for all sorts of diseases. The rationale is that their antioxidant activity would prevent free radical damage to macromolecules. However, basic and clinical science is showing that the reality is much more complex than this and that several issues, notably content in foodstuff, bioavailability, or in vivo antioxidant activity are yet to be resolved. We summarize the recent findings concerning the effects of polyphenols on human health, analyze the current limitations at pitfalls, and propose future directions for research.
Polyphenols and Human Health: A Prospectus / F., Visioli; C. A., De; C., Andres Lacueva; M., Aviram; C., Calhau; A., Cassano; M., D'Archivio; A., Faria; G., Fave; Fogliano, Vincenzo; R., Llorach; Vitaglione, Paola; M., Zoratti; M., Edeas. - In: CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION. - ISSN 1040-8398. - ELETTRONICO. - 51:(2011), pp. 524-546. [10.1080/10408391003698677]
Polyphenols and Human Health: A Prospectus
FOGLIANO, VINCENZO;VITAGLIONE, PAOLA;
2011
Abstract
The lay press often heralds polyphenols as panacea for all sorts of diseases. The rationale is that their antioxidant activity would prevent free radical damage to macromolecules. However, basic and clinical science is showing that the reality is much more complex than this and that several issues, notably content in foodstuff, bioavailability, or in vivo antioxidant activity are yet to be resolved. We summarize the recent findings concerning the effects of polyphenols on human health, analyze the current limitations at pitfalls, and propose future directions for research.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
