IRIS
DE SIMONE, Alfonso
 Distribuzione geografica
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Continente #
NA - Nord America 801
EU - Europa 238
AS - Asia 116
AF - Africa 2
Continente sconosciuto - Info sul continente non disponibili 1
Totale 1.158
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Nazione #
US - Stati Uniti d'America 795
IT - Italia 121
SG - Singapore 83
DE - Germania 38
FI - Finlandia 20
SE - Svezia 19
CN - Cina 17
GB - Regno Unito 10
JP - Giappone 9
NL - Olanda 6
CA - Canada 5
SI - Slovenia 4
IE - Irlanda 3
PH - Filippine 3
PL - Polonia 3
CZ - Repubblica Ceca 2
FR - Francia 2
HK - Hong Kong 2
IN - India 2
RO - Romania 2
SK - Slovacchia (Repubblica Slovacca) 2
BE - Belgio 1
CH - Svizzera 1
CI - Costa d'Avorio 1
EU - Europa 1
GH - Ghana 1
GR - Grecia 1
HR - Croazia 1
MK - Macedonia 1
MX - Messico 1
UA - Ucraina 1
Totale 1.158
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Città #
Millbury 139
Lawrence 105
Chandler 103
Des Moines 78
Ashburn 52
Singapore 48
Naples 33
Wilmington 32
Napoli 21
Seattle 20
Fairfield 17
Helsinki 15
Woodbridge 12
Florence 9
Boston 8
Nanjing 7
Rome 7
Kronberg 6
Rockville 6
Chicago 5
Bacoli 4
Bracciano 4
Kawasaki 4
Lappeenranta 4
Norwalk 4
Redwood City 4
Scuola 4
Torino 4
Xian 4
Šentjernej 4
Bad Krozingen 3
Karlsruhe 3
Wroclaw 3
Amsterdam 2
Benevento 2
Bratislava 2
Edinburgh 2
Fulham 2
Garbagnate Milanese 2
Hong Kong 2
Jiaxing 2
Manila 2
Novara 2
Nuremberg 2
Sennori 2
Amyntaio 1
Ann Arbor 1
Ariano Irpino 1
Bern 1
Boardman 1
Brussels 1
Bucharest 1
Cologne 1
Council Bluffs 1
Dublin 1
Geislingen an der Steige 1
Gricignano di Aversa 1
Hermosillo 1
Horia 1
Huizen 1
Kamampa 1
Landshut 1
Limatola 1
London 1
Los Angeles 1
Loughborough 1
Milan 1
New York 1
Newark 1
Newcastle upon Tyne 1
Portici 1
Princeton 1
Pune 1
San Pablo City 1
Santa Maria a Vico 1
Tianjin 1
Tokyo 1
Toronto 1
Vancouver 1
Victoria 1
Weng 1
Zagreb 1
Totale 833
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Nome #
Membrane Interactions and Toxicity by Misfolded Protein Oligomers 39
Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer's Disease, Parkinson's Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis 30
Backbone NMR assignments of the C-terminal domain of the human prion protein and its disease-associated T183A variant 26
Accurate random coil chemical shifts from an analysis of loop regions in native states of proteins 25
Correlation between ω and ψ dihedral angles in protein structures 25
The docking of synaptic vesicles on the presynaptic membrane induced by α-synuclein is modulated by lipid composition 25
Blocking von Willebrand factor free thiols inhibits binding to collagen under high and pathological shear stress 25
Conformational modifications of gB from Herpes simplex virus type 1 analyzed by synthetic peptides 24
Advances in modelling alpha-synuclein-induced Parkinson's diseases in rodents: Virus-based models versus inoculation of exogenous preformed toxic species 21
Accurate Determination of Conformational Transitions in Oligomeric Membrane Proteins 20
Characterizing protein crystal contacts and their role in crystallization: Rubredoxin as a case study 19
Structural and Dynamic properties of incomplete immunoglobulin-like fold domains 19
Backbone NMR assignments of HypF-N under conditions generating toxic and non-toxic oligomers 19
Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity 18
Biochemical and biophysical comparison of human and mouse beta-2 microglobulin reveals the molecular determinants of low amyloid propensity 18
Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease 17
Cryptic binding properties of a transient folding intermediate in a PDZ tandem repeat 17
Characterizing intermolecular interactions that initiate native-like protein aggregation 17
Molecular determinants of inactivation of the resuscitation promoting factor B from Mycobacterium tuberculosis 17
Sequence Specificity in the Entropy-Driven Binding of a Small Molecule and a Disordered Peptide 17
C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction 17
A Carboxylate to Amide Substitution That Switches Protein Folds 16
Structural basis for allosteric control of the SERCA-Phospholamban membrane complex by Ca2+ and phosphorylation 15
Structural differences between toxic and nontoxic HypF-N oligomers 15
Modeling Parkinson’s disease neuropathology and symptoms by intranigral inoculation of preformed human α-synuclein oligomers 15
Structural basis of membrane disruption and cellular toxicity by a-synuclein oligomers 15
Characterization of the conformational equilibrium between the two major substates of RNase a using NMR chemical shifts 15
Intrinsic structural versatility of the highly conserved 412–423 epitope of the Hepatitis C Virus E2 protein 15
Molecular determinants of the interaction of EGCG with ordered and disordered proteins 14
Probing the Origin of the Toxicity of Oligomeric Aggregates of α-Synuclein with Antibodies 14
Small-molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer's disease 14
Atomic structure and hierarchical assembly of a cross-β amyloid fibril 14
Amyloid β Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies 14
Structure and dynamics of the multi-domain resuscitation promoting factor RpfB from Mycobacterium tuberculosis 14
In silico study of the mechanism of binding of the N-terminal region of α synuclein to synaptic-like membranes 13
1H, 13C and 15N resonance assignments of human muscle acylphosphatase 13
The crystal structure of the streptococcal collagen-like protein 2 globular domain from invasive M3-type group a streptococcus shows significant similarity to immunomodulatory HIV protein gp41 13
Prion and water: Tight and dynamical hydration sites have a key role in structural stability 13
Glucokinase gene mutations: Structural and genotype-phenotype analyses in MODY children from South Italy 13
Water molecules as structural determinants among prions of low sequence identity 13
Carbohydrate recognition by RpfB from mycobacterium tuberculosis unveiled by crystallographic and molecular dynamics analyses 12
Determination of conformational equilibria in proteins using residual dipolar couplings 12
Structural Basis for Natural Product Selection and Export by Bacterial ABC Transporters 12
Local structural motifs in proteins: Detection and characterization of fragments inserted in helices 12
Characterization of the Conformational Fluctuations in the Josephin Domain of Ataxin-3 11
The structure of Resuscitation promoting factor B from M. tuberculosis reveals unexpected ubiquitin-like domains 11
A structural overview of mycobacterial adhesins: Key biomarkers for diagnostics and therapeutics 11
The Toxicity of Misfolded Protein Oligomers Is Independent of Their Secondary Structure 11
The N-terminal Acetylation of α-Synuclein Changes the Affinity for Lipid Membranes but not the Structural Properties of the Bound State 11
null 10
Toward understanding the molecular bases of stretch activation: A structural comparison of the two troponin C isoforms of Lethocerus 10
A Role of Cholesterol in Modulating the Binding of α-Synuclein to Synaptic-Like Vesicles 10
Demonstration of Binding Induced Structural Plasticity in a SH2 Domain 10
Cavitation energies can outperform dispersion interactions 10
Artificial heme-enzymes for the construction of functional nanomaterials 9
MetalHawk: Enhanced Classification of Metal Coordination Geometries by Artificial Neural Networks 9
Characterization of the interdomain motions in hen lysozyme using residual dipolar couplings as replica-averaged structural restraints in molecular dynamics simulations 9
Dynamical properties of steric zipper polymorphs formed by a IAPP-derived peptide 9
Twisting transition between crystalline and fibrillar phases of aggregated peptides 9
Metal interactions of α-synuclein probed by NMR amide-proton exchange 8
Classification of metal site coordination number and geometry through artificial neural networks 8
Electrostatically-guided inhibition of Curli amyloid nucleation by the CsgC-like family of chaperones 8
Structural characterization of a misfolded intermediate populated during the folding process of a PDZ domain 8
Structure, dynamics, and stability of assemblies of the human prion fragment SNQNNF 8
Conformational recognition of an intrinsically disordered protein 7
Structure-Free Validation of Residual Dipolar Coupling and Paramagnetic Relaxation Enhancement Measurements of Disordered Proteins 7
The inverted free energy landscape of an intrinsically disordered peptide by simulations and experiments 7
Limited tendency of α-helical residues to form disulfide bridges: A structural explanation 7
Role of side chains in collagen triple helix stabilization and partner recognition 7
Probing the dynamic stalk region of the ribosome using solution NMR 7
The role of structural dynamics in the thermal adaptation of hyperthermophilic enzymes 6
Structure-Toxicity Relationship in Intermediate Fibrils from α-Synuclein Condensates 6
The Intranigral Infusion of Human-Alpha Synuclein Oligomers Induces a Cognitive Impairment in Rats Associated with Changes in Neuronal Firing and Neuroinflammation in the Anterior Cingulate Cortex 6
Thermal tuning of protein hydration in a hyperthermophilic enzyme 6
Release of high-energy water as an essential driving force for the high-affinity binding of cucurbit[n]urils 6
Structure and dynamics of the integrin LFA-1 I-domain in the inactive state underlie its inside-out/outside-in signaling and allosteric mechanisms 6
Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour 6
Computational studies of the structure, dynamics and native content of amyloid-like fibrils of ribonuclease A 6
New opportunities for tensor-free calculations of residual dipolar couplings for the study of protein dynamics 6
Structural Ensembles of Membrane-bound α-Synuclein Reveal the Molecular Determinants of Synaptic Vesicle Affinity 6
FOR the RECORD: Role of loops connecting secondary structure elements in the stabilization of proteins isolated from thermophilic organisms 6
Cucurbit[8]uril and blue-box: High-energy water release overwhelms electrostatic interactions 6
Structural basis of synaptic vesicle assembly promoted by α-synuclein 6
Multi-scale simulations provide supporting evidence for the hypothesis of intramolecular protein translocation in GroEL/GroES complexes 6
Role of hydration in collagen triple helix stabilization 6
Intrinsic disorder modulates protein self-assembly and aggregation 6
Role of hydration in collagen recognition by bacterial adhesins 6
Substitutions at residue 211 in the prion protein drive a switch between CJD and GSS syndrome, a new mechanism governing inherited neurodegenerative disorders 6
The Josephin domain determines the morphological and mechanical properties of ataxin-3 fibrils 6
Determination of structural fluctuations of proteins from structure-based calculations of residual dipolar couplings 6
Order and disorder in the physiological membrane binding of α-synuclein 6
Desolvation of the substrate-binding protein TauA dictates ligand specificity for the alkanesulfonate ABC importer TauABC 6
Mechanism of misfolding of the human prion protein revealed by a pathological mutation 6
Local Backbone Geometry Plays a Critical Role in Determining Conformational Preferences of Amino Acid Residues in Proteins 6
Protein kinase R dependent phosphorylation of α-synuclein regulates its membrane binding and aggregation 5
Editorial: Oligomers in amyloid-associated diseases-structural properties and toxicity 5
Plasticity of Membrane Binding by the Central Region of α-Synuclein 5
Enhancing Biomolecular Simulations with Hybrid Potentials Incorporating NMR Data 5
Region-specific changes in gene expression are associated with cognitive deficits in the alpha-synuclein-induced model of Parkinson's disease: A transcriptomic profiling study 5
Structure of a low-population intermediate state in the release of an enzyme product 5
Totale 1.177
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Categoria #
all - tutte 8.911
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 8.911
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20205 4 1 0 0 0 0 0 0 0 0 0 0
2020/2021210 0 0 0 0 0 0 19 151 29 1 5 5
2021/2022328 11 9 1 1 9 10 4 25 12 1 16 229
2022/2023449 155 29 12 11 37 39 1 65 67 5 24 4
2023/2024314 21 34 39 18 19 14 6 45 7 8 103 0
Totale 1.308