IRIS
DE SIMONE, Alfonso
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 1.212
AS - Asia 860
EU - Europa 568
SA - Sud America 65
AF - Africa 7
Continente sconosciuto - Info sul continente non disponibili 1
OC - Oceania 1
Totale 2.714
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 1.198
SG - Singapore 508
HK - Hong Kong 270
IT - Italia 198
RU - Federazione Russa 142
DE - Germania 78
BR - Brasile 57
FI - Finlandia 55
CN - Cina 48
GB - Regno Unito 20
SE - Svezia 19
AT - Austria 12
NL - Olanda 11
CA - Canada 10
JP - Giappone 9
IN - India 7
BD - Bangladesh 6
AR - Argentina 5
FR - Francia 5
BE - Belgio 4
IQ - Iraq 4
MX - Messico 4
SI - Slovenia 4
IE - Irlanda 3
PH - Filippine 3
PL - Polonia 3
CZ - Repubblica Ceca 2
LT - Lituania 2
PE - Perù 2
RO - Romania 2
SK - Slovacchia (Repubblica Slovacca) 2
ZA - Sudafrica 2
AU - Australia 1
BA - Bosnia-Erzegovina 1
CH - Svizzera 1
CI - Costa d'Avorio 1
CO - Colombia 1
DZ - Algeria 1
EU - Europa 1
GH - Ghana 1
GR - Grecia 1
HR - Croazia 1
IL - Israele 1
MA - Marocco 1
MK - Macedonia 1
PK - Pakistan 1
PS - Palestinian Territory 1
SN - Senegal 1
TJ - Tagikistan 1
TR - Turchia 1
UA - Ucraina 1
Totale 2.714
Salva come PNG Salva come JPEG
Città #
Singapore 303
Hong Kong 270
Santa Clara 248
Millbury 139
Lawrence 105
Chandler 103
Naples 86
Des Moines 78
Ashburn 56
Helsinki 50
Seattle 36
Wilmington 32
Napoli 21
Falkenstein 19
Fairfield 17
Nuremberg 12
Woodbridge 12
Rome 11
Florence 9
Boston 8
Nanjing 7
Cambridge 6
Kronberg 6
Moscow 6
Rockville 6
Toronto 6
Chicago 5
Dallas 5
Bacoli 4
Bracciano 4
Brussels 4
Karlsruhe 4
Kawasaki 4
Lappeenranta 4
Mumbai 4
Munich 4
Norwalk 4
Redwood City 4
Scuola 4
Torino 4
Xian 4
Šentjernej 4
Amsterdam 3
Bad Krozingen 3
Brasília 3
Cagliari 3
Casagiove 3
Porto Alegre 3
Santo André 3
Vienna 3
Wroclaw 3
Benevento 2
Bratislava 2
Düsseldorf 2
Edinburgh 2
Fulham 2
Garbagnate Milanese 2
Guangzhou 2
Jiaxing 2
Lauterbourg 2
London 2
Manila 2
Mosul 2
Novara 2
Recife 2
Rochdale 2
Sennori 2
Shanghai 2
St Petersburg 2
São Paulo 2
Union City 2
Adelaide 1
Altamura 1
Amyntaio 1
Andradas 1
Angatuba 1
Angra dos Reis 1
Ann Arbor 1
Aparecida de Goiânia 1
Ariano Irpino 1
Baliza 1
Banfield 1
Batna City 1
Beijing 1
Belo Horizonte 1
Berlin 1
Bern 1
Boardman 1
Boca do Acre Municipality 1
Bom Jesus de Goiás 1
Bucharest 1
Caieiras 1
Cajamar 1
Campinas 1
Cape Town 1
Casablanca 1
Catanduva 1
Changchun 1
Changsha 1
Chengdu 1
Totale 1.814
Salva come PNG Salva come JPEG
Nome #
Membrane Interactions and Toxicity by Misfolded Protein Oligomers 52
Classification of metal site coordination number and geometry through artificial neural networks 45
Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer's Disease, Parkinson's Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis 44
Conformational modifications of gB from Herpes simplex virus type 1 analyzed by synthetic peptides 40
Accurate random coil chemical shifts from an analysis of loop regions in native states of proteins 40
Artificial heme-enzymes for the construction of functional nanomaterials 39
Blocking von Willebrand factor free thiols inhibits binding to collagen under high and pathological shear stress 38
Intrinsic structural versatility of the highly conserved 412–423 epitope of the Hepatitis C Virus E2 protein 38
Correlation between ω and ψ dihedral angles in protein structures 37
Structural differences between toxic and nontoxic HypF-N oligomers 36
Molecular determinants of inactivation of the resuscitation promoting factor B from Mycobacterium tuberculosis 36
Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity 35
Advances in modelling alpha-synuclein-induced Parkinson's diseases in rodents: Virus-based models versus inoculation of exogenous preformed toxic species 35
Small-molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer's disease 34
Backbone NMR assignments of HypF-N under conditions generating toxic and non-toxic oligomers 34
Backbone NMR assignments of the C-terminal domain of the human prion protein and its disease-associated T183A variant 33
The docking of synaptic vesicles on the presynaptic membrane induced by α-synuclein is modulated by lipid composition 32
Characterization of the conformational equilibrium between the two major substates of RNase a using NMR chemical shifts 32
C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction 32
Biochemical and biophysical comparison of human and mouse beta-2 microglobulin reveals the molecular determinants of low amyloid propensity 32
Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease 31
Structural basis for allosteric control of the SERCA-Phospholamban membrane complex by Ca2+ and phosphorylation 31
Region-specific changes in gene expression are associated with cognitive deficits in the alpha-synuclein-induced model of Parkinson's disease: A transcriptomic profiling study 30
Modeling Parkinson’s disease neuropathology and symptoms by intranigral inoculation of preformed human α-synuclein oligomers 30
Characterizing protein crystal contacts and their role in crystallization: Rubredoxin as a case study 30
Structural and Dynamic properties of incomplete immunoglobulin-like fold domains 30
Structural basis of membrane disruption and cellular toxicity by a-synuclein oligomers 30
Cryptic binding properties of a transient folding intermediate in a PDZ tandem repeat 29
Sequence Specificity in the Entropy-Driven Binding of a Small Molecule and a Disordered Peptide 29
Prion and water: Tight and dynamical hydration sites have a key role in structural stability 29
Glucokinase gene mutations: Structural and genotype-phenotype analyses in MODY children from South Italy 29
The N-terminal Acetylation of α-Synuclein Changes the Affinity for Lipid Membranes but not the Structural Properties of the Bound State 29
Probing the Origin of the Toxicity of Oligomeric Aggregates of α-Synuclein with Antibodies 28
1H, 13C and 15N resonance assignments of human muscle acylphosphatase 28
Accurate Determination of Conformational Transitions in Oligomeric Membrane Proteins 28
Water molecules as structural determinants among prions of low sequence identity 28
A Carboxylate to Amide Substitution That Switches Protein Folds 28
α-Synuclein and biological membranes: the danger of loving too much 27
Characterizing intermolecular interactions that initiate native-like protein aggregation 27
The Toxicity of Misfolded Protein Oligomers Is Independent of Their Secondary Structure 27
Molecular determinants of the interaction of EGCG with ordered and disordered proteins 26
The role of structural dynamics in the thermal adaptation of hyperthermophilic enzymes 25
MetalHawk: Enhanced Classification of Metal Coordination Geometries by Artificial Neural Networks 25
Structure and dynamics of the multi-domain resuscitation promoting factor RpfB from Mycobacterium tuberculosis 25
Structure, dynamics, and stability of assemblies of the human prion fragment SNQNNF 25
A structural overview of mycobacterial adhesins: Key biomarkers for diagnostics and therapeutics 25
In silico study of the mechanism of binding of the N-terminal region of α synuclein to synaptic-like membranes 24
Characterization of the Conformational Fluctuations in the Josephin Domain of Ataxin-3 24
The crystal structure of the streptococcal collagen-like protein 2 globular domain from invasive M3-type group a streptococcus shows significant similarity to immunomodulatory HIV protein gp41 24
Catalytic Nanomaterials by Conjugation of an Artificial Heme-Peroxidase to Amyloid Fibrils 23
Atomic structure and hierarchical assembly of a cross-β amyloid fibril 23
Amyloid β Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies 23
A Role of Cholesterol in Modulating the Binding of α-Synuclein to Synaptic-Like Vesicles 23
Local structural motifs in proteins: Detection and characterization of fragments inserted in helices 23
Demonstration of Binding Induced Structural Plasticity in a SH2 Domain 23
Metal interactions of α-synuclein probed by NMR amide-proton exchange 22
Carbohydrate recognition by RpfB from mycobacterium tuberculosis unveiled by crystallographic and molecular dynamics analyses 22
The structure of Resuscitation promoting factor B from M. tuberculosis reveals unexpected ubiquitin-like domains 22
Structural Basis for Natural Product Selection and Export by Bacterial ABC Transporters 22
Order and disorder in the physiological membrane binding of α-synuclein 22
α-Synuclein and Mitochondria: Probing the Dynamics of Disordered Membrane-protein Regions Using Solid-State Nuclear Magnetic Resonance 21
Repurposing Pomalidomide as a Neuroprotective Drug: Efficacy in an Alpha-Synuclein-Based Model of Parkinson’s Disease 21
Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour 21
Role of side chains in collagen triple helix stabilization and partner recognition 21
Dynamical properties of steric zipper polymorphs formed by a IAPP-derived peptide 21
Structural Ensembles of Membrane-bound α-Synuclein Reveal the Molecular Determinants of Synaptic Vesicle Affinity 20
Toward understanding the molecular bases of stretch activation: A structural comparison of the two troponin C isoforms of Lethocerus 20
Determination of conformational equilibria in proteins using residual dipolar couplings 20
Role of hydration in collagen recognition by bacterial adhesins 20
The PROSECCO server for chemical shift predictions in ordered and disordered proteins 20
Twisting transition between crystalline and fibrillar phases of aggregated peptides 20
Cavitation energies can outperform dispersion interactions 20
Structure-Toxicity Relationship in Intermediate Fibrils from α-Synuclein Condensates 19
Conformational recognition of an intrinsically disordered protein 19
Structure-Free Validation of Residual Dipolar Coupling and Paramagnetic Relaxation Enhancement Measurements of Disordered Proteins 19
Substitutions at residue 211 in the prion protein drive a switch between CJD and GSS syndrome, a new mechanism governing inherited neurodegenerative disorders 19
Force-field dependence of chignolin folding and misfolding: Comparison with experiment and redesign 19
Plasticity of Membrane Binding by the Central Region of α-Synuclein 18
Probing the dynamic stalk region of the ribosome using solution NMR 18
Mechanism of misfolding of the human prion protein revealed by a pathological mutation 18
A kink in DWORF helical structure controls the activation of the sarcoplasmic reticulum Ca2+-ATPase 17
The Intranigral Infusion of Human-Alpha Synuclein Oligomers Induces a Cognitive Impairment in Rats Associated with Changes in Neuronal Firing and Neuroinflammation in the Anterior Cingulate Cortex 17
Characterization of the interdomain motions in hen lysozyme using residual dipolar couplings as replica-averaged structural restraints in molecular dynamics simulations 17
Release of high-energy water as an essential driving force for the high-affinity binding of cucurbit[n]urils 17
The Josephin domain determines the morphological and mechanical properties of ataxin-3 fibrils 17
Editorial: Oligomers in amyloid-associated diseases-structural properties and toxicity 16
Thermal tuning of protein hydration in a hyperthermophilic enzyme 16
Structure and dynamics of the integrin LFA-1 I-domain in the inactive state underlie its inside-out/outside-in signaling and allosteric mechanisms 16
Structural and hydration properties of the partially unfolded states of the prion protein 16
Intrinsic disorder modulates protein self-assembly and aggregation 16
Structural characterization of a misfolded intermediate populated during the folding process of a PDZ domain 16
Toward the understanding of MNEI sweetness from hydration map surfaces 16
The intrinsic stability of the human prion β-sheet region investigated by molecular dynamics 16
Toward an accurate determination of free energy landscapes in solution states of proteins 15
Electrostatically-guided inhibition of Curli amyloid nucleation by the CsgC-like family of chaperones 15
New opportunities for tensor-free calculations of residual dipolar couplings for the study of protein dynamics 15
The inverted free energy landscape of an intrinsically disordered peptide by simulations and experiments 15
Structural basis of synaptic vesicle assembly promoted by α-synuclein 15
Determination of structural fluctuations of proteins from structure-based calculations of residual dipolar couplings 15
Local Backbone Geometry Plays a Critical Role in Determining Conformational Preferences of Amino Acid Residues in Proteins 15
Totale 2.505
Salva come PNG Salva come JPEG
Categoria #
all - tutte 18.191
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 18.191
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021210 0 0 0 0 0 0 19 151 29 1 5 5
2021/2022328 11 9 1 1 9 10 4 25 12 1 16 229
2022/2023449 155 29 12 11 37 39 1 65 67 5 24 4
2023/2024387 21 34 39 18 19 14 6 45 7 8 120 56
2024/20251.496 162 123 28 33 126 229 300 195 237 63 0 0
Totale 2.877