TROISI, ROMUALDO
TROISI, ROMUALDO
DIPARTIMENTO DI SCIENZE CHIMICHE
Peculiar structural features of NU172: the only thrombin binding aptamer currently in phase II clinical trials
2016 Troisi, Romualdo; RUSSO KRAUSS, Irene; Napolitano, Valeria; Sica, Filomena
Structural basis for the recognition of human alpha-thrombin by NU172: the only thrombin binding aptamer currently in phase II clinical trials
2017 Troisi, Romualdo; RUSSO KRAUSS, Irene; Napolitano, Valeria; Sica, Filomena
Structural features of a duplex-quadruplex anti-thrombin aptamer: the highly effective NU172
2018 Troisi, Romualdo; Napolitano, Valeria; RUSSO KRAUSS, Irene; Sica, Filomena
Structural motifs determining the high anti-thrombin activity of NU172, an aptamer currently in Phase II clinical trials
2018 Troisi, Romualdo; Napolitano, Valeria; RUSSO KRAUSS, Irene; Sica, Filomena
Molecular dynamics simulations shed light on the cooperative mechanisms generated by the simultaneous binding of aptamers at the two exosites of thrombin”
2019 Sica, Filomena; Troisi, Romualdo; Balasco, Nicole
“Salmo salar ribonuclease: structural and functional evidences of an auto inhibition mechanism”
2019 Russo Krauss, I.; Merlino, A.; Pizzo, E.; Bosso, A.; Faella, Rita; Carluccio, C.; Trapani, M.; Troisi, R.; Mazzarella, L.; Sica, F.
Communication between thrombin exosites: structural effects of the simultaneous binding of two bimodular aptamers
2019 Troisi, R.; Santamaria, Andreas; Balasco, N.; Sica, Filomena
Structural basis for the recognition of human α-thrombin by NU172: the only thrombin binding aptamer currently in phase II clinical trials
2017 Troisi, R.; Russo Krauss, I.; Napolitano, V.; Sica, F.
Several structural motifs cooperate in determining the highly effective anti-thrombin activity of NU172 aptamer
2018 Troisi, Romualdo; Napolitano, Valeria; Spiridonova, Vera; RUSSO KRAUSS, Irene; Sica, Filomena
Duplex/quadruplex oligonucleotides: Role of the duplex domain in the stabilization of a new generation of highly effective anti-thrombin aptamers
2018 Russo Krauss, Irene; Napolitano, Valeria; Petraccone, Luigi; Troisi, Romualdo; Spiridonova, Vera; Mattia, Carlo Andrea; Sica, Filomena
Molecular dynamics simulations of human α-thrombin in different structural contexts: evidence for an aptamer-guided cooperation between the two exosites
2021 Troisi, R.; Balasco, N.; Vitagliano, L.; Sica, F.
Expanding the recognition interface of the thrombin-binding aptamer HD1 through modification of residues T3 and T12
2021 Smirnov, Igor; Kolganova, Natalia; Troisi, Romualdo; Sica, Filomena; Timofeev, Edward
Protective Effects of Recombinant Human Angiogenin in Keratinocytes: New Insights on Oxidative Stress Response Mediated by RNases
2022 Culurciello, Rosanna; Bosso, Andrea; Troisi, Romualdo; Barrella, Valentina; Di Nardo, Ilaria; Borriello, Margherita; Gaglione, Rosa; Pistorio, Valeria; Aceto, Serena; Cafaro, Valeria; Notomista, Eugenio; Sica, Filomena; Arciello, Angela; Pizzo, Elio
Structural and functional analysis of the simultaneous binding of two duplex/quadruplex aptamers to human α-thrombin
2021 Troisi, Romualdo; Balasco, Nicole; Santamaria, Andreas; Vitagliano, Luigi; Sica, Filomena
Aptamers: Functional-Structural Studies and Biomedical Applications
2022 Troisi, Romualdo; Sica, Filomena
Antimicrobial Applications of Green Synthesized Bimetallic Nanoparticles from Ocimum basilicum
2022 Rajendra More, Pragati; Zannella, Carla; Folliero, Veronica; Foglia, Francesco; Troisi, Romualdo; Vergara, Alessandro; Franci, Gianluigi; De Filippis, Anna; Galdiero, Massimiliano
Cisplatin Binding to Human Serum Transferrin: A Crystallographic Study
2023 Troisi, R.; Galardo, F.; Ferraro, G.; Sica, F.; Merlino, A.
A terminal functionalization strategy reveals unusual binding abilities of anti-thrombin anticoagulant aptamers
2022 Troisi, Romualdo; Riccardi, Claudia; Pérez de Carvasal, Kévan; Smietana, Michael; Morvan, François; Del Vecchio, Pompea; Montesarchio, Daniela; Sica, Filomena
Dirhodium tetraacetate binding to a B-DNA double helical dodecamer probed by X-ray crystallography and mass spectrometry
2023 Tito, G.; Troisi, R.; Ferraro, G.; Geri, A.; Massai, L.; Messori, L.; Sica, F.; Merlino, A.
Structure–Activity Relationship Study of a Potent α-Thrombin Binding Aptamer Incorporating Hexitol Nucleotides
2020 De Fenza, M.; Eremeeva, E.; Troisi, R.; Yang, H.; Esposito, Anna; Sica, F.; Herdewijn, P.; D'Alonzo, D.; Guaragna, A.
Titolo | Tipologia | Data di pubblicazione | Autore(i) | File |
---|---|---|---|---|
Peculiar structural features of NU172: the only thrombin binding aptamer currently in phase II clinical trials | 4.2 Abstract in Atti di convegno | 2016 | Troisi, Romualdo; RUSSO KRAUSS, Irene; Napolitano, Valeria; Sica, Filomena | |
Structural basis for the recognition of human alpha-thrombin by NU172: the only thrombin binding aptamer currently in phase II clinical trials | 4.1 Articoli in Atti di convegno | 2017 | Troisi, Romualdo; RUSSO KRAUSS, Irene; Napolitano, Valeria; Sica, Filomena | |
Structural features of a duplex-quadruplex anti-thrombin aptamer: the highly effective NU172 | 4.2 Abstract in Atti di convegno | 2018 | Troisi, Romualdo; Napolitano, Valeria; RUSSO KRAUSS, Irene; Sica, Filomena | |
Structural motifs determining the high anti-thrombin activity of NU172, an aptamer currently in Phase II clinical trials | 4.2 Abstract in Atti di convegno | 2018 | Troisi, Romualdo; Napolitano, Valeria; RUSSO KRAUSS, Irene; Sica, Filomena | |
Molecular dynamics simulations shed light on the cooperative mechanisms generated by the simultaneous binding of aptamers at the two exosites of thrombin” | 4.2 Abstract in Atti di convegno | 2019 | Sica, Filomena; Troisi, Romualdo; Balasco, Nicole | |
“Salmo salar ribonuclease: structural and functional evidences of an auto inhibition mechanism” | 4.2 Abstract in Atti di convegno | 2019 | Russo Krauss, I.; Merlino, A.; Pizzo, E.; Bosso, A.; Faella, Rita; Carluccio, C.; Trapani, M.; Troisi, R.; Mazzarella, L.; Sica, F. | |
Communication between thrombin exosites: structural effects of the simultaneous binding of two bimodular aptamers | 4.2 Abstract in Atti di convegno | 2019 | Troisi, R.; Santamaria, Andreas; Balasco, N.; Sica, Filomena | |
Structural basis for the recognition of human α-thrombin by NU172: the only thrombin binding aptamer currently in phase II clinical trials | 4.2 Abstract in Atti di convegno | 2017 | Troisi, R.; Russo Krauss, I.; Napolitano, V.; Sica, F. | |
Several structural motifs cooperate in determining the highly effective anti-thrombin activity of NU172 aptamer | 1.1 Articolo in rivista | 2018 | Troisi, Romualdo; Napolitano, Valeria; Spiridonova, Vera; RUSSO KRAUSS, Irene; Sica, Filomena | |
Duplex/quadruplex oligonucleotides: Role of the duplex domain in the stabilization of a new generation of highly effective anti-thrombin aptamers | 1.1 Articolo in rivista | 2018 | Russo Krauss, Irene; Napolitano, Valeria; Petraccone, Luigi; Troisi, Romualdo; Spiridonova, Vera; Mattia, Carlo Andrea; Sica, Filomena | |
Molecular dynamics simulations of human α-thrombin in different structural contexts: evidence for an aptamer-guided cooperation between the two exosites | 1.1 Articolo in rivista | 2021 | Troisi, R.; Balasco, N.; Vitagliano, L.; Sica, F. | |
Expanding the recognition interface of the thrombin-binding aptamer HD1 through modification of residues T3 and T12 | 1.1 Articolo in rivista | 2021 | Smirnov, Igor; Kolganova, Natalia; Troisi, Romualdo; Sica, Filomena; Timofeev, Edward | |
Protective Effects of Recombinant Human Angiogenin in Keratinocytes: New Insights on Oxidative Stress Response Mediated by RNases | 1.1 Articolo in rivista | 2022 | Culurciello, Rosanna; Bosso, Andrea; Troisi, Romualdo; Barrella, Valentina; Di Nardo, Ilaria; Borriello, Margherita; Gaglione, Rosa; Pistorio, Valeria; Aceto, Serena; Cafaro, Valeria; Notomista, Eugenio; Sica, Filomena; Arciello, Angela; Pizzo, Elio | |
Structural and functional analysis of the simultaneous binding of two duplex/quadruplex aptamers to human α-thrombin | 1.1 Articolo in rivista | 2021 | Troisi, Romualdo; Balasco, Nicole; Santamaria, Andreas; Vitagliano, Luigi; Sica, Filomena | |
Aptamers: Functional-Structural Studies and Biomedical Applications | 1.1 Articolo in rivista | 2022 | Troisi, Romualdo; Sica, Filomena | |
Antimicrobial Applications of Green Synthesized Bimetallic Nanoparticles from Ocimum basilicum | 1.1 Articolo in rivista | 2022 | Rajendra More, Pragati; Zannella, Carla; Folliero, Veronica; Foglia, Francesco; Troisi, Romualdo; Vergara, Alessandro; Franci, Gianluigi; De Filippis, Anna; Galdiero, Massimiliano | |
Cisplatin Binding to Human Serum Transferrin: A Crystallographic Study | 1.1 Articolo in rivista | 2023 | Troisi, R.; Galardo, F.; Ferraro, G.; Sica, F.; Merlino, A. | |
A terminal functionalization strategy reveals unusual binding abilities of anti-thrombin anticoagulant aptamers | 1.1 Articolo in rivista | 2022 | Troisi, Romualdo; Riccardi, Claudia; Pérez de Carvasal, Kévan; Smietana, Michael; Morvan, François; Del Vecchio, Pompea; Montesarchio, Daniela; Sica, Filomena | |
Dirhodium tetraacetate binding to a B-DNA double helical dodecamer probed by X-ray crystallography and mass spectrometry | 1.1 Articolo in rivista | 2023 | Tito, G.; Troisi, R.; Ferraro, G.; Geri, A.; Massai, L.; Messori, L.; Sica, F.; Merlino, A. | |
Structure–Activity Relationship Study of a Potent α-Thrombin Binding Aptamer Incorporating Hexitol Nucleotides | 1.1 Articolo in rivista | 2020 | De Fenza, M.; Eremeeva, E.; Troisi, R.; Yang, H.; Esposito, Anna; Sica, F.; Herdewijn, P.; D'Alonzo, D.; Guaragna, A. |