PASSARIELLO, MARGHERITA

PASSARIELLO, MARGHERITA  

Dipartimento di Medicina molecolare e Biotecnologie mediche  

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Immune checkpoint inhibitor therapy increases systemic SDF-1, cardiac DAMPs Fibronectin-EDA, S100/Calgranulin, galectine-3, and NLRP3-MyD88-chemokine pathways 1.1 Articolo in rivista 2022 Quagliariello, Vincenzo; Passariello, Margherita; Di Mauro, Annabella; Cipullo, Ciro; Paccone, Andrea; Barbieri, Antonio; Palma, Giuseppe; Luciano, Antonio; Buccolo, Simona; Bisceglia, Irma; Canale, Maria Laura; Gallucci, Giuseppina; Inno, Alessandro; De Lorenzo, Claudia; Maurea, Nicola
Oncolytic Adenoviral Vector-Mediated Expression of an Anti-PD-L1-scFv Improves Anti-Tumoral Efficacy in a Melanoma Mouse Model 1.1 Articolo in rivista 2022 Vitale, M.; Scialo, F.; Passariello, M.; Leggiero, E.; D'Agostino, A.; Tripodi, L.; Gentile, L.; Bianco, A.; Castaldo, G.; Cerullo, V.; De Lorenzo, C.; Pastore, L.
Novel tri-specific tribodies induce strong T cell activation and anti-tumor effects in vitro and in vivo 1.1 Articolo in rivista 2022 Passariello, M.; Yoshioka, A.; Takahashi, K.; Hashimoto, S. -I.; Inoue, T.; Nakamura, K.; De Lorenzo, C.
A Novel Human Neutralizing mAb Recognizes Delta, Gamma and Omicron Variants of SARS-CoV-2 and Can Be Used in Combination with Sotrovimab 1.1 Articolo in rivista 2022 Passariello, Margherita; Ferrucci, Veronica; Sasso, Emanuele; Manna, Lorenzo; Lembo, Rosa Rapuano; Pascarella, Stefano; Fusco, Giovanna; Zambrano, Nicola; Zollo, Massimo; De Lorenzo, Claudia
Rapid Affinity Maturation of Novel Anti-PD-L1 Antibodies by a Fast Drop of the Antigen Concentration and FACS Selection of Yeast Libraries 1.1 Articolo in rivista 2019 Cembrola, B; Ruzza, V; Troise, F; Esposito, Ml; Sasso, E; Cafaro, V; Passariello, M; Visconte, F; Raia, M; Del Vecchio, L; D'Alise, Am; Cortese, R; Scarselli, E; Zambrano, N; De Lorenzo, C; Nicosia, A
High-Throughput Monoclonal Antibody Discovery from Phage Libraries: Challenging the Current Preclinical Pipeline to Keep the Pace with the Increasing mAb Demand 1.1 Articolo in rivista 2022 Zambrano, Nicola; Froechlich, Guendalina; Lazarevic, Dejan; Passariello, Margherita; Nicosia, Alfredo; De Lorenzo, Claudia; Morelli, Marco J.; Sasso, Emanuele
Novel combinations of human immunomodulatory mAbs lacking cardiotoxic effects for therapy of TNBC 1.1 Articolo in rivista 2022 Vetrei, C.; Passariello, M.; Froechlich, G.; Lembo, R. R.; Sasso, E.; Zambrano, N.; De Lorenzo, C.
Evaluation of the antiproliferative effect of Bifidobacterium longum BB-536 in solid tumor cell lines, co-cultured with murine splenocytes 1.1 Articolo in rivista 2021 Tripodi, L.; Passariello, M.; D'Argenio, V.; Leggiero, E.; Vitale, M.; Colicchio, R.; Salvatore, P.; Cerullo, V.; De Lorenzo, C.; Pastore, L.
Interactions of spike‐rbd of sars‐cov‐2 and platelet factor 4: New insights in the etiopathogenesis of thrombosis 1.1 Articolo in rivista 2021 Passariello, M.; Vetrei, C.; Amato, F.; De Lorenzo, C.
Novel human neutralizing mAbs specific for Spike-RBD of SARS-CoV-2 1.1 Articolo in rivista 2021 Passariello, M.; Gentile, C.; Ferrucci, V.; Sasso, E.; Vetrei, C.; Fusco, G.; Viscardi, M.; Brandi, S.; Cerino, P.; Zambrano, N.; Zollo, M.; De Lorenzo, C.
Immunomodulatory mabs as tools to investigate on cis-interaction of pd-1/pd-l1 on tumor cells and to set up methods for early screening of safe and potent combinatorial treatments 1.1 Articolo in rivista 2021 Vetrei, C.; Passariello, M.; Froechlich, G.; Lembo, R. R.; Zambrano, N.; De Lorenzo, C.
Aptamer targeted therapy potentiates immune checkpoint blockade in triple-negative breast cancer 1.1 Articolo in rivista 2020 Camorani, Simona; Passariello, Margherita; Agnello, Lisa; Esposito, Silvia; Collina, Francesca; Cantile, Monica; Di Bonito, Maurizio; Ulasov, Ilya V; Fedele, Monica; Zannetti, Antonella; De Lorenzo, Claudia; Cerchia, Laura
Evidences of CTLA-4 and PD-1 blocking agents-induced cardiotoxicity in cellular and preclinical models 1.1 Articolo in rivista 2020 Quagliariello, V.; Passariello, M.; Rea, D.; Barbieri, A.; Iovine, M.; Bonelli, A.; Caronna, A.; Botti, G.; De Lorenzo, C.; Maurea, N.
Massive parallel screening of phage libraries for the generation of repertoires of human immunomodulatory monoclonal antibodies. 1.1 Articolo in rivista 2018 Sasso, E; D'Avino, C; Passariello, M; D'Alise, Am; Siciliano, D; Esposito, Ml; Froechlich, Guendalina; Cortese, R; Scarselli, E; Zambrano, N; Nicosia, A; De Lorenzo, C.
Superior Suppression of ErbB2-positive Tumor Cells by a Novel Human Triparatopic Tribody 1.1 Articolo in rivista 2017 Riccio, Gennaro; Da Fonseca Ricardo, Ana R; Passariello, Margherita; Cunnah, Philip; Mertens, Nico; DE LORENZO, Claudia
Cardiotoxicity and pro-inflammatory effects of the immune checkpoint inhibitor Pembrolizumab associated to Trastuzumab 1.1 Articolo in rivista 2019 Quagliariello, V; Passariello, Margherita; Coppola, C; Rea D., D; Barbieri, A.; Scherillo, M.; Monti, M. G.; Iaffaioli, R. V.; Laurentiis, De; Ascierto, Pa.; Botti, G.; De Lorenzo, Claudia.; Maurea, N.
Novel Human Anti-PD-L1 mAbs Inhibit Immune-Independent Tumor Cell Growth and PD-L1 Associated Intracellular Signalling 1.1 Articolo in rivista 2019 Passariello, M; D'Alise, Am; Esposito, A; Vetrei, C; Froechlich, Guendalina; Scarselli, E; Nicosia, A; De Lorenzo, C.
T-cell Activating Tribodies as a Novel Approach for Efficient Killing of ErbB2-positive Cancer Cells. 1.1 Articolo in rivista 2019 Riccio, G; Ricardo, Ar; Passariello, M; Saraiva, K; Rubino, V; Cunnah, P; Mertens, N; De Lorenzo, C.
Novel Human Bispecific Aptamer-Antibody Conjugates for Efficient Cancer Cell Killing 1.1 Articolo in rivista 2019 Passariello, M; Camorani, S; Vetrei, Cinzia; Cerchia, L; De Lorenzo, C.
A long non-coding SINEUP RNA boosts semi-stable production of fully human monoclonal antibodies in HEK293E cells 1.1 Articolo in rivista 2018 Sasso, Emanuele; Latino, Debora; Froechlich, Guendalina; Succoio, Mariangela; Passariello, Margherita; De Lorenzo, Claudia; Nicosia, Alfredo; Zambrano, Nicola