SORRENTINO, NICOLINA CRISTINA
SORRENTINO, NICOLINA CRISTINA
DIPARTIMENTO DI MEDICINA CLINICA E CHIRURGIA
A highly secreted sulphamidase engineered to cross the blood-brain barrier corrects brain lesions of mice with mucopolysaccharidoses type IIIA.
2013 Sorrentino, Nc; D'Orsi, L; Sambri, I; Nusco, E; Monaco, C; Spampanato, C; Polishchuk, E; Saccone, P; De Leonibus, E; Ballabio, Andrea; Fraldi, Alessandro
Disease rescue and increased lifespan in a model of cardiomyopathy and muscular dystrophy by combined AAV treatments.
2009 Vitiello, C.; Faraso, S.; Sorrentino, N. C.; Nusco, E.; Nigro, G.; Cutillo, L.; Calabrò, R.; Auricchio, Alberto; Nigro, V.
Transdermal spinal catheter placement in piglets: Description and validation of the technique.
2015 Lambertini, C; Ventrella, D; Barone, F; Sorrentino, Nc; Dondi, F; Fraldi, Alessandro; Giunti, M; Surace, Enrico Maria; Bacci, Ml; Romagnoli, N.
A comprehensive map of CNS transduction by eight recombinant adeno-associated virus serotypes upon cerebrospinal fluid administration in pigs
2016 Sorrentino, Nicolina Cristina; Maffia, Veronica; Strollo, Sandra; Cacace, Vincenzo; Romagnoli, Noemi; Manfredi, Anna; Ventrella, Domenico; Dondi, Francesco; Barone, Francesca; Giunti, Massimo; Graham, Anne Renee; Huang, Yan; Kalled, Susan L; Auricchio, Alberto; Bacci, Maria Laura; Surace, Enrico Maria; Fraldi, Alessandro
Access to cerebrospinal fluid in piglets via the cisterna magna: Optimization and description of the technique
2014 Romagnoli, Noemi; Ventrella, Domenico; Giunti, Massimo; Dondi, Francesco; Sorrentino, Nicolina C.; Fraldi, Alessandro; Surace, Enrico Maria; Bacci, Maria L.
Lysosomal dysfunction disrupts presynaptic maintenance and restoration of presynaptic function prevents neurodegeneration in lysosomal storage diseases
2017 Sambri, Irene; D'Alessio, Rosa; Ezhova, Yulia; Giuliano, Teresa; Sorrentino, Nicolina Cristina; Cacace, Vincenzo; De Risi, Maria; Cataldi, Mauro; Annunziato, Lucio; De Leonibus, Elvira; Fraldi, Alessandro
Brain Targeting in MPS-IIIA
2016 Sorrentino, Nicolina Cristina; Fraldi, Alessandro
Efficacy of a combined intracerebral and systemic gene delivery approach for the treatment of a severe lysosomal storage disorder.
2011 Spampanato, C; De Leonibus, E; Dama, P; Gargiulo, A; Fraldi, Alessandro; Sorrentino, Nc; Russo, F; Nusco, E; Auricchio, Alberto; Surace, Enrico Maria; Ballabio, Andrea
Gene therapy for mucopolysaccharidoses: in vivo and ex vivo approaches
2018 Fraldi, Alessandro; Serafini, Marta; Sorrentino, Nicolina Cristina; Gentner, Bernhard; Aiuti, Alessandro; Bernardo, Maria Ester
Enhancing the Therapeutic Potential of Sulfamidase for the Treatment of Mucopolysaccharidosis IIIA
2019 Sorrentino, N. C.; Cacace, Valeria; De Risi, M.; Maffia, V.; Strollo, S.; Tedesco, Nicola; Nusco, Luisa Emilia; Romagnoli, N.; Ventrella, D.; Huang, Y.; Liu, N.; Kalled, S. L.; Choi, V. W.; De Leonibus, E.; Fraldi, A.
The Amyloid Inhibitor CLR01 Relieves Autophagy and Ameliorates Neuropathology in a Severe Lysosomal Storage Disease
2020 Monaco, A.; Maffia, V.; Sorrentino, N. C.; Sambri, I.; Ezhova, Y.; Giuliano, T.; Cacace, V.; Nusco, E.; De Risi, M.; De Leonibus, E.; Schrader, T.; Klarner, F. -G.; Bitan, G.; Fraldi, A.
Enhanced Version of Human Sulfamidase Significantly Ameliorates CNS Pathology When Delivered to the MPS-IIIA Mice by AAV-Mediated Intra-CSF Injection
2018 Sorrentino, Nicolina C.; Cacace, Vincenzo; Maffia, Veronica; Strollo, Sandra; Tedesco, Novella; Nusco, Edoardo; Romagnoli, Noemi; Ventrella, Domenico; Barone, Francesca; laura Bacci, Maria; Huang, Yan; Liu, Nan; Kalled, Susan; Choi, Vivian; Fraldi, Alessandro
Glycosaminoglycan levels and structure in a mucopolysaccharidosis IIIA mice and the effect of a highly secreted sulfamidase engineered to cross the blood-brain barrier
2017 Maccari, F.; Sorrentino, N. C.; Mantovani, V.; Galeotti, F.; Fraldi, A.; Volpi, N.
Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders
2010 Fraldi, A; Annunziata, F; Lombardi, A; Kaiser, Hj; Medina, Dl.; Spampanato, C; Fedele, Ao; Polishchuk, R; Sorrentino, Nc; Simons, K; Ballabio, A.
Effects of non-euphoric plant cannabinoids on muscle quality and performance of dystrophic mdx mice
2019 Iannotti, Fabio Arturo; Pagano, Ester; Moriello, Aniello Schiano; Alvino, Filomena Grazia; Sorrentino, Nicolina Cristina; D'Orsi, Luca; Gazzerro, Elisabetta; Capasso, Raffaele; De Leonibus, Elvira; De Petrocellis, Luciano; Di Marzo, Vincenzo
Fluoxetine ameliorates mucopolysaccharidosis type IIIA
2022 Capuozzo, A.; Montefusco, S.; Cacace, V.; Sofia, M.; Esposito, A.; Napolitano, G.; Nusco, E.; Polishchuk, E.; Pizzo, M. T.; De Risi, M.; De Leonibus, E.; Sorrentino, N. C.; MEDINA SANABRIA, Diego Luis
Therapy of sulfatase deficiencies
2019 Ballabio, A; Sorrentino, Nc; Fraldi, A
New mouse models with hypomorphic SUMF1 variants mimic attenuated forms of multiple sulfatase deficiency
2022 Sorrentino, Nicolina Cristina; Presa, Maximiliano; Attanasio, Sergio; Cacace, Vincenzo; Sofia, Martina; Zuberi, Aamir; Ryan, Jennifer; Ray, Somdatta; Petkovic, Igor; Radhakrishnan, Karthikeyan; Schlotawa, Lars; Ballabio, Andrea; Lutz, Cathleen; Brunetti-Pierri, Nicola
TFEB and TFE3 drive kidney cystogenesis and tumorigenesis
2023 Di Malta, Chiara; Zampelli, Angela; Granieri, Letizia; Vilardo, Claudia; De Cegli, Rossella; Cinque, Laura; Nusco, Edoardo; Pece, Salvatore; Tosoni, Daniela; Sanguedolce, Francesca; Sorrentino, Nicolina Cristina; Merino, Maria J; Nielsen, Deborah; Srinivasan, Ramaprasad; Ball, Mark W; Ricketts, Christopher J; Vocke, Cathy D; Lang, Martin; Karim, Baktiar; Lanfrancone, Luisa; Schmidt, Laura S; Linehan, W Marston; Ballabio, Andrea
Increased expression or activation of TRPML1 reduces hepatic storage of toxic Z alpha-1 antitrypsin
2023 Pastore, Nunzia; Annunziata, Francesco; Colonna, Rita; Maffia, Veronica; Giuliano, Teresa; Custode, Bruno Maria; Lombardi, Bernadette; Polishchuk, Elena; Cacace, Vincenzo; De Stefano, Lucia; Nusco, Edoardo; Sorrentino, Nicolina Cristina; Piccolo, Pasquale; Brunetti-Pierri, Nicola
| Titolo | Tipologia | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|---|
| A highly secreted sulphamidase engineered to cross the blood-brain barrier corrects brain lesions of mice with mucopolysaccharidoses type IIIA. | 1.1 Articolo in rivista | 2013 | Sorrentino, Nc; D'Orsi, L; Sambri, I; Nusco, E; Monaco, C; Spampanato, C; Polishchuk, E; Saccone, P; De Leonibus, E; Ballabio, Andrea; Fraldi, Alessandro | |
| Disease rescue and increased lifespan in a model of cardiomyopathy and muscular dystrophy by combined AAV treatments. | 1.1 Articolo in rivista | 2009 | Vitiello, C.; Faraso, S.; Sorrentino, N. C.; Nusco, E.; Nigro, G.; Cutillo, L.; Calabrò, R.; Auricchio, Alberto; Nigro, V. | |
| Transdermal spinal catheter placement in piglets: Description and validation of the technique. | 1.1 Articolo in rivista | 2015 | Lambertini, C; Ventrella, D; Barone, F; Sorrentino, Nc; Dondi, F; Fraldi, Alessandro; Giunti, M; Surace, Enrico Maria; Bacci, Ml; Romagnoli, N. | |
| A comprehensive map of CNS transduction by eight recombinant adeno-associated virus serotypes upon cerebrospinal fluid administration in pigs | 1.1 Articolo in rivista | 2016 | Sorrentino, Nicolina Cristina; Maffia, Veronica; Strollo, Sandra; Cacace, Vincenzo; Romagnoli, Noemi; Manfredi, Anna; Ventrella, Domenico; Dondi, Francesco; Barone, Francesca; Giunti, Massimo; Graham, Anne Renee; Huang, Yan; Kalled, Susan L; Auricchio, Alberto; Bacci, Maria Laura; Surace, Enrico Maria; Fraldi, Alessandro | |
| Access to cerebrospinal fluid in piglets via the cisterna magna: Optimization and description of the technique | 1.1 Articolo in rivista | 2014 | Romagnoli, Noemi; Ventrella, Domenico; Giunti, Massimo; Dondi, Francesco; Sorrentino, Nicolina C.; Fraldi, Alessandro; Surace, Enrico Maria; Bacci, Maria L. | |
| Lysosomal dysfunction disrupts presynaptic maintenance and restoration of presynaptic function prevents neurodegeneration in lysosomal storage diseases | 1.1 Articolo in rivista | 2017 | Sambri, Irene; D'Alessio, Rosa; Ezhova, Yulia; Giuliano, Teresa; Sorrentino, Nicolina Cristina; Cacace, Vincenzo; De Risi, Maria; Cataldi, Mauro; Annunziato, Lucio; De Leonibus, Elvira; Fraldi, Alessandro | |
| Brain Targeting in MPS-IIIA | 1.1 Articolo in rivista | 2016 | Sorrentino, Nicolina Cristina; Fraldi, Alessandro | |
| Efficacy of a combined intracerebral and systemic gene delivery approach for the treatment of a severe lysosomal storage disorder. | 1.1 Articolo in rivista | 2011 | Spampanato, C; De Leonibus, E; Dama, P; Gargiulo, A; Fraldi, Alessandro; Sorrentino, Nc; Russo, F; Nusco, E; Auricchio, Alberto; Surace, Enrico Maria; Ballabio, Andrea | |
| Gene therapy for mucopolysaccharidoses: in vivo and ex vivo approaches | 1.1 Articolo in rivista | 2018 | Fraldi, Alessandro; Serafini, Marta; Sorrentino, Nicolina Cristina; Gentner, Bernhard; Aiuti, Alessandro; Bernardo, Maria Ester | |
| Enhancing the Therapeutic Potential of Sulfamidase for the Treatment of Mucopolysaccharidosis IIIA | 1.1 Articolo in rivista | 2019 | Sorrentino, N. C.; Cacace, Valeria; De Risi, M.; Maffia, V.; Strollo, S.; Tedesco, Nicola; Nusco, Luisa Emilia; Romagnoli, N.; Ventrella, D.; Huang, Y.; Liu, N.; Kalled, S. L.; Choi, V. W.; De Leonibus, E.; Fraldi, A. | |
| The Amyloid Inhibitor CLR01 Relieves Autophagy and Ameliorates Neuropathology in a Severe Lysosomal Storage Disease | 1.1 Articolo in rivista | 2020 | Monaco, A.; Maffia, V.; Sorrentino, N. C.; Sambri, I.; Ezhova, Y.; Giuliano, T.; Cacace, V.; Nusco, E.; De Risi, M.; De Leonibus, E.; Schrader, T.; Klarner, F. -G.; Bitan, G.; Fraldi, A. | |
| Enhanced Version of Human Sulfamidase Significantly Ameliorates CNS Pathology When Delivered to the MPS-IIIA Mice by AAV-Mediated Intra-CSF Injection | 4.2 Abstract in Atti di convegno | 2018 | Sorrentino, Nicolina C.; Cacace, Vincenzo; Maffia, Veronica; Strollo, Sandra; Tedesco, Novella; Nusco, Edoardo; Romagnoli, Noemi; Ventrella, Domenico; Barone, Francesca; laura Bacci, Maria; Huang, Yan; Liu, Nan; Kalled, Susan; Choi, Vivian; Fraldi, Alessandro | |
| Glycosaminoglycan levels and structure in a mucopolysaccharidosis IIIA mice and the effect of a highly secreted sulfamidase engineered to cross the blood-brain barrier | 1.1 Articolo in rivista | 2017 | Maccari, F.; Sorrentino, N. C.; Mantovani, V.; Galeotti, F.; Fraldi, A.; Volpi, N. | |
| Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders | 1.1 Articolo in rivista | 2010 | Fraldi, A; Annunziata, F; Lombardi, A; Kaiser, Hj; Medina, Dl.; Spampanato, C; Fedele, Ao; Polishchuk, R; Sorrentino, Nc; Simons, K; Ballabio, A. | |
| Effects of non-euphoric plant cannabinoids on muscle quality and performance of dystrophic mdx mice | 1.1 Articolo in rivista | 2019 | Iannotti, Fabio Arturo; Pagano, Ester; Moriello, Aniello Schiano; Alvino, Filomena Grazia; Sorrentino, Nicolina Cristina; D'Orsi, Luca; Gazzerro, Elisabetta; Capasso, Raffaele; De Leonibus, Elvira; De Petrocellis, Luciano; Di Marzo, Vincenzo | |
| Fluoxetine ameliorates mucopolysaccharidosis type IIIA | 1.1 Articolo in rivista | 2022 | Capuozzo, A.; Montefusco, S.; Cacace, V.; Sofia, M.; Esposito, A.; Napolitano, G.; Nusco, E.; Polishchuk, E.; Pizzo, M. T.; De Risi, M.; De Leonibus, E.; Sorrentino, N. C.; MEDINA SANABRIA, Diego Luis | |
| Therapy of sulfatase deficiencies | 6.1 Brevetto | 2019 | Ballabio, A; Sorrentino, Nc; Fraldi, A | |
| New mouse models with hypomorphic SUMF1 variants mimic attenuated forms of multiple sulfatase deficiency | 1.1 Articolo in rivista | 2022 | Sorrentino, Nicolina Cristina; Presa, Maximiliano; Attanasio, Sergio; Cacace, Vincenzo; Sofia, Martina; Zuberi, Aamir; Ryan, Jennifer; Ray, Somdatta; Petkovic, Igor; Radhakrishnan, Karthikeyan; Schlotawa, Lars; Ballabio, Andrea; Lutz, Cathleen; Brunetti-Pierri, Nicola | |
| TFEB and TFE3 drive kidney cystogenesis and tumorigenesis | 1.1 Articolo in rivista | 2023 | Di Malta, Chiara; Zampelli, Angela; Granieri, Letizia; Vilardo, Claudia; De Cegli, Rossella; Cinque, Laura; Nusco, Edoardo; Pece, Salvatore; Tosoni, Daniela; Sanguedolce, Francesca; Sorrentino, Nicolina Cristina; Merino, Maria J; Nielsen, Deborah; Srinivasan, Ramaprasad; Ball, Mark W; Ricketts, Christopher J; Vocke, Cathy D; Lang, Martin; Karim, Baktiar; Lanfrancone, Luisa; Schmidt, Laura S; Linehan, W Marston; Ballabio, Andrea | |
| Increased expression or activation of TRPML1 reduces hepatic storage of toxic Z alpha-1 antitrypsin | 1.1 Articolo in rivista | 2023 | Pastore, Nunzia; Annunziata, Francesco; Colonna, Rita; Maffia, Veronica; Giuliano, Teresa; Custode, Bruno Maria; Lombardi, Bernadette; Polishchuk, Elena; Cacace, Vincenzo; De Stefano, Lucia; Nusco, Edoardo; Sorrentino, Nicolina Cristina; Piccolo, Pasquale; Brunetti-Pierri, Nicola |