IRIS
LA PIETRA, VALERIA
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 576
EU - Europa 337
AS - Asia 145
AF - Africa 31
Continente sconosciuto - Info sul continente non disponibili 1
Totale 1.090
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 558
IT - Italia 174
CN - Cina 113
NL - Olanda 59
IE - Irlanda 45
FI - Finlandia 34
CI - Costa d'Avorio 30
CA - Canada 18
GB - Regno Unito 10
IN - India 8
VN - Vietnam 8
IR - Iran 6
TR - Turchia 5
DE - Germania 4
FR - Francia 2
JP - Giappone 2
SE - Svezia 2
SG - Singapore 2
BE - Belgio 1
CZ - Repubblica Ceca 1
EE - Estonia 1
EG - Egitto 1
EU - Europa 1
HU - Ungheria 1
KH - Cambogia 1
MK - Macedonia 1
PL - Polonia 1
RO - Romania 1
Totale 1.090
Salva come PNG Salva come JPEG
Città #
Chandler 151
Amsterdam 59
Ashburn 46
Millbury 44
Napoli 41
Princeton 34
Beijing 32
Nanjing 31
Naples 25
Des Moines 22
Ottawa 18
Boston 15
Wilmington 10
Augusta 9
Dong Ket 8
Hebei 8
Lawrence 8
Nanchang 8
Santa Maria Capua Vetere 8
Shenyang 8
Milan 7
Rome 7
San Mateo 6
Dearborn 5
Tianjin 5
Changsha 4
Chicago 4
Filottrano 4
Jiaxing 4
Bologna 3
Caserta 3
Dublin 3
Los Angeles 3
Pune 3
Seattle 3
Ann Arbor 2
Ardabil 2
Arzano 2
Edinburgh 2
Florence 2
Hangzhou 2
Houston 2
Jacksonville 2
Jinan 2
Kunming 2
Lappeenranta 2
Leawood 2
Mugnano di Napoli 2
Ningbo 2
Quarto 2
San Giuliano 2
Taizhou 2
Tokyo 2
Torre del Greco 2
Washington 2
Woodbridge 2
Acerra 1
Altamura 1
Antwerp 1
Banstead 1
Brescia 1
Budapest 1
Cagliari 1
Casoria 1
Castrop-rauxel 1
Ceppaloni 1
Darmstadt 1
Falls Church 1
Fremont 1
Greenwich 1
Guangzhou 1
Helsinki 1
Ilford 1
Ischia 1
Islington 1
Istanbul 1
Mountain View 1
New Kensington 1
New York 1
Norwalk 1
Orange 1
Parma 1
Phnom Penh 1
Pianoro 1
Piombino 1
Prague 1
Rho 1
Sabz 1
Salerno 1
San Benedetto Del Tronto 1
San Giorgio del Sannio 1
Shenzhen 1
Solofra 1
Tallinn 1
Trieste 1
Turin 1
Warsaw 1
Zhengzhou 1
Totale 733
Salva come PNG Salva come JPEG
Nome #
Computer-Aided Identification and Lead Optimization of Dual Murine Double Minute 2 and 4 Binders: Structure-Activity Relationship Studies and Pharmacological Activity 65
Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells 53
Structure-based lead optimization and biological evaluation of BAX direct activators as novel potential anticancer agents 52
Exploring the N-Terminal Region of C-X-C Motif Chemokine 12 (CXCL12): Identification of Plasma-Stable Cyclic Peptides As Novel, Potent C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonists 46
A more detailed picture of the interactions between virtual screening-derived hits and the DNA G-quadruplex: NMR, molecular modelling and ITC studies. 37
Benzothiopyranoindole- and pyridothiopyranoindole-based antiproliferative agents targeting topoisomerases 37
A more detailed picture of the interactions between Virtual Screening-derived Hits and the DNA G-Quadruplex: NMR, Molecular Modeling and ITC Studies 36
Novel peptidomimetics as BACE-1 inhibitors: synthesis, molecular modeling, and biological studies 33
State-of-the-art methodologies for the discovery and characterization of DNA G-Quadruplex binders 32
Challenging clinically unresponsive medullary thyroid cancer: Discovery and pharmacological activity of novel RET inhibitors 32
Apoptosis Therapy in Cancer: The First Single-molecule Co-activating p53 and the Translocator Protein in Glioblastoma 31
Discovery of Covalent Inhibitors of Glyceraldehyde-3-phosphate Dehydrogenase, A Target for the Treatment of Malaria 31
Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent to Combat Alzheimer's Disease 31
Human recombinant beta-secretase immobilized enzyme reactor for fast hits' selection and characterization from a virtual screening library 30
Long lasting inhibition of Mdm2-p53 interaction potentiates mesenchymal stem cell differentiation into osteoblasts 30
Arylsulfonamide inhibitors of aggrecanases as potential therapeutic agents for osteoarthritis: Synthesis and biological evaluation 29
Progresses in the pursuit of aldose reductase inhibitors: the structure-based lead optimization step. 27
Receptor-bound conformation of cilengitide better represented by its solution-state structure than the solid-state structure 27
Development of novel dipeptide-like rhodesain inhibitors containing the 3-bromoisoxazoline warhead in a constrained conformation 27
Enriching the arsenal of pharmacological tools against mical2 27
Interfering with the Tumor-Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors 27
Best Matching Protein Conformations and Docking Programs for a Virtual Screening Campaign Against SMO Receptor 26
Identification of novel molecular scaffolds for the design of MMP-13 inhibitors: A first round of lead optimization. 25
Identification of Glycogen Synthase Kinase-3 Inhibitors with a Selective Sting for Glycogen Synthase Kinase-3α 25
p53 Functional Inhibitors Behaving Like Pifithrin-? Counteract the Alzheimer Peptide Non-?-amyloid Component Effects in Human SH-SY5Y Cells 23
Design, Synthesis, and Biological Evaluation of 1-Phenylpyrazolo[3,4-e]pyrrolo[3,4-g]indolizine-4,6(1H,5H)-diones as New Glycogen Synthase Kinase-3 beta Inhibitors 22
Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis 22
N-O-ISOPROPYL SULFONAMIDO-BASED HYDROXAMATES: KINETIC CHARACTERISATION OF A SERIES OF MMP-12/MMP-13 DUAL TARGET INHIBITORS. 21
Lead Optimization of 2-Phenylindolylglyoxylyldipeptide Murine Double Minute (MDM)2/Translocator Protein (TSPO) Dual Inhibitors for the Treatment of Gliomas 21
Site-directed Mutagenesis of Key Residues Unveiled a Novel Allosteric Site on Human Adenosine Kinase for Pyrrolobenzoxa(thia)zepinone Non-Nucleoside Inhibitors 21
Simultaneous Targeting of RGD-Integrins and Dual Murine Double Minute Proteins in Glioblastoma Multiforme 21
Theoretical and experimental studies on the interaction of biphenyl ligands with human and murine PD-L1: Up-to-date clues for drug design 20
A novel cell-permeable, selective, and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach 20
Non-nucleoside inhibitors of human adenosine kinase: synthesis, molecular modeling, and biological studies. 19
A stereoselective approach to peptidomimetic BACE1 inhibitors 19
HuR-targeted agents: An insight into medicinal chemistry, biophysical, computational studies and pharmacological effects on cancer models 19
Identification of a Novel p53 Modulator Endowed with Antitumoural and Antibacterial Activity through a Scaffold Repurposing Approach 18
Potent Arylsulfonamide Inhibitors of Tumor Necrosis Factor-alfa Converting Enzyme Able to Reduce Activated Leukocyte Cell Adhesion Molecule Shedding in Cancer Cell Models 18
Protein Flexibility in Virtual Screening: The BACE-1 Case Study 18
null 18
Structure-Based Optimization of Tyrosine Kinase InhibitorCLM3. Design, Synthesis, Functional Evaluation, and Molecular Modeling Studies. 18
HuR modulation counteracts lipopolysaccharide response in murine macrophages 15
Synthesis and biological evaluation in U87MG glioma cells of (ethynylthiophene)sulfonamido-based hydroxamates as matrix metalloproteinase inhibitors. 14
N-O-Isopropyl Sulfonamido-Based Hydroxamates: Design, Synthesis and Biological Evaluation of Selective Matrix Metalloproteinase-13 Inhibitors as Potential Therapeutic Agents for Osteoarthritis 12
CXCR4 antagonism sensitizes cancer cells to novel indole-based MDM2/4 inhibitors in glioblastoma multiforme 12
Selective Arylsulfonamide Inhibitors of ADAM-17: Hit Optimization and Activity in Ovarian Cancer Cell Models 7
A combined approach of structure‐based virtual screening and NMR to interrupt the PD‐1/PD‐L1 axis: Biphenyl‐benzimidazole containing compounds as novel PD‐L1 inhibitors 3
Totale 1.217
Salva come PNG Salva come JPEG
Categoria #
all - tutte 4.977
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 4.977
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201916 0 0 0 0 0 0 0 0 0 0 5 11
2019/2020157 59 8 1 1 32 3 4 1 0 14 26 8
2020/2021106 5 1 4 1 2 32 2 10 13 1 25 10
2021/2022226 3 2 4 1 4 1 0 12 51 36 22 90
2022/2023363 42 15 13 34 40 44 0 28 55 60 27 5
2023/2024202 24 26 35 24 18 24 11 35 1 3 1 0
Totale 1.217