LA PIETRA, VALERIA
 Distribuzione geografica
Continente #
NA - Nord America 578
EU - Europa 346
AS - Asia 183
AF - Africa 31
Continente sconosciuto - Info sul continente non disponibili 1
Totale 1.139
Nazione #
US - Stati Uniti d'America 560
IT - Italia 180
CN - Cina 114
NL - Olanda 59
IE - Irlanda 45
SG - Singapore 39
FI - Finlandia 34
CI - Costa d'Avorio 30
CA - Canada 18
GB - Regno Unito 10
IN - India 8
VN - Vietnam 8
IR - Iran 6
TR - Turchia 5
DE - Germania 4
FR - Francia 4
HU - Ungheria 2
JP - Giappone 2
SE - Svezia 2
BE - Belgio 1
CZ - Repubblica Ceca 1
EE - Estonia 1
EG - Egitto 1
EU - Europa 1
KH - Cambogia 1
MK - Macedonia 1
PL - Polonia 1
RO - Romania 1
Totale 1.139
Città #
Chandler 151
Amsterdam 59
Ashburn 46
Millbury 44
Napoli 41
Princeton 34
Beijing 32
Nanjing 31
Naples 27
Singapore 23
Des Moines 22
Ottawa 18
Boston 15
Wilmington 10
Augusta 9
Dong Ket 8
Hebei 8
Lawrence 8
Nanchang 8
Santa Maria Capua Vetere 8
Shenyang 8
Milan 7
Rome 7
San Mateo 6
Bologna 5
Dearborn 5
Tianjin 5
Changsha 4
Chicago 4
Filottrano 4
Jiaxing 4
Caserta 3
Dublin 3
Hangzhou 3
Los Angeles 3
Pune 3
Seattle 3
Ann Arbor 2
Ardabil 2
Arzano 2
Budapest 2
Edinburgh 2
Florence 2
Houston 2
Jacksonville 2
Jinan 2
Kunming 2
Lappeenranta 2
Leawood 2
Mugnano di Napoli 2
Ningbo 2
Quarto 2
San Giuliano 2
Sandston 2
Taizhou 2
Tokyo 2
Torre del Greco 2
Washington 2
Woodbridge 2
Acerra 1
Altamura 1
Antwerp 1
Banstead 1
Brescia 1
Cagliari 1
Casoria 1
Castrop-rauxel 1
Ceppaloni 1
Darmstadt 1
Falls Church 1
Fremont 1
Greenwich 1
Guangzhou 1
Helsinki 1
Ilford 1
Ischia 1
Islington 1
Istanbul 1
Mountain View 1
New Kensington 1
New York 1
Norwalk 1
Orange 1
Parma 1
Phnom Penh 1
Pianoro 1
Piombino 1
Prague 1
Rho 1
Sabz 1
Salerno 1
San Benedetto Del Tronto 1
San Giorgio del Sannio 1
Shenzhen 1
Solofra 1
Spineda 1
Tallinn 1
Trieste 1
Turin 1
Warsaw 1
Totale 764
Nome #
Computer-Aided Identification and Lead Optimization of Dual Murine Double Minute 2 and 4 Binders: Structure-Activity Relationship Studies and Pharmacological Activity 67
Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells 54
Structure-based lead optimization and biological evaluation of BAX direct activators as novel potential anticancer agents 53
Exploring the N-Terminal Region of C-X-C Motif Chemokine 12 (CXCL12): Identification of Plasma-Stable Cyclic Peptides As Novel, Potent C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonists 47
A more detailed picture of the interactions between virtual screening-derived hits and the DNA G-quadruplex: NMR, molecular modelling and ITC studies. 38
A more detailed picture of the interactions between Virtual Screening-derived Hits and the DNA G-Quadruplex: NMR, Molecular Modeling and ITC Studies 37
Benzothiopyranoindole- and pyridothiopyranoindole-based antiproliferative agents targeting topoisomerases 37
State-of-the-art methodologies for the discovery and characterization of DNA G-Quadruplex binders 34
Novel peptidomimetics as BACE-1 inhibitors: synthesis, molecular modeling, and biological studies 34
Apoptosis Therapy in Cancer: The First Single-molecule Co-activating p53 and the Translocator Protein in Glioblastoma 32
Discovery of Covalent Inhibitors of Glyceraldehyde-3-phosphate Dehydrogenase, A Target for the Treatment of Malaria 32
Challenging clinically unresponsive medullary thyroid cancer: Discovery and pharmacological activity of novel RET inhibitors 32
Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent to Combat Alzheimer's Disease 32
Human recombinant beta-secretase immobilized enzyme reactor for fast hits' selection and characterization from a virtual screening library 31
Long lasting inhibition of Mdm2-p53 interaction potentiates mesenchymal stem cell differentiation into osteoblasts 31
Interfering with the Tumor-Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors 31
Arylsulfonamide inhibitors of aggrecanases as potential therapeutic agents for osteoarthritis: Synthesis and biological evaluation 29
Progresses in the pursuit of aldose reductase inhibitors: the structure-based lead optimization step. 28
Enriching the arsenal of pharmacological tools against mical2 28
Receptor-bound conformation of cilengitide better represented by its solution-state structure than the solid-state structure 27
Development of novel dipeptide-like rhodesain inhibitors containing the 3-bromoisoxazoline warhead in a constrained conformation 27
Best Matching Protein Conformations and Docking Programs for a Virtual Screening Campaign Against SMO Receptor 27
Identification of novel molecular scaffolds for the design of MMP-13 inhibitors: A first round of lead optimization. 26
Identification of Glycogen Synthase Kinase-3 Inhibitors with a Selective Sting for Glycogen Synthase Kinase-3α 25
p53 Functional Inhibitors Behaving Like Pifithrin-? Counteract the Alzheimer Peptide Non-?-amyloid Component Effects in Human SH-SY5Y Cells 24
Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis 23
N-O-ISOPROPYL SULFONAMIDO-BASED HYDROXAMATES: KINETIC CHARACTERISATION OF A SERIES OF MMP-12/MMP-13 DUAL TARGET INHIBITORS. 22
Design, Synthesis, and Biological Evaluation of 1-Phenylpyrazolo[3,4-e]pyrrolo[3,4-g]indolizine-4,6(1H,5H)-diones as New Glycogen Synthase Kinase-3 beta Inhibitors 22
Lead Optimization of 2-Phenylindolylglyoxylyldipeptide Murine Double Minute (MDM)2/Translocator Protein (TSPO) Dual Inhibitors for the Treatment of Gliomas 22
Site-directed Mutagenesis of Key Residues Unveiled a Novel Allosteric Site on Human Adenosine Kinase for Pyrrolobenzoxa(thia)zepinone Non-Nucleoside Inhibitors 22
Theoretical and experimental studies on the interaction of biphenyl ligands with human and murine PD-L1: Up-to-date clues for drug design 21
Non-nucleoside inhibitors of human adenosine kinase: synthesis, molecular modeling, and biological studies. 21
A stereoselective approach to peptidomimetic BACE1 inhibitors 21
Simultaneous Targeting of RGD-Integrins and Dual Murine Double Minute Proteins in Glioblastoma Multiforme 21
A novel cell-permeable, selective, and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach 20
HuR-targeted agents: An insight into medicinal chemistry, biophysical, computational studies and pharmacological effects on cancer models 20
Protein Flexibility in Virtual Screening: The BACE-1 Case Study 19
Structure-Based Optimization of Tyrosine Kinase InhibitorCLM3. Design, Synthesis, Functional Evaluation, and Molecular Modeling Studies. 19
Identification of a Novel p53 Modulator Endowed with Antitumoural and Antibacterial Activity through a Scaffold Repurposing Approach 18
Potent Arylsulfonamide Inhibitors of Tumor Necrosis Factor-alfa Converting Enzyme Able to Reduce Activated Leukocyte Cell Adhesion Molecule Shedding in Cancer Cell Models 18
null 18
HuR modulation counteracts lipopolysaccharide response in murine macrophages 16
N-O-Isopropyl Sulfonamido-Based Hydroxamates: Design, Synthesis and Biological Evaluation of Selective Matrix Metalloproteinase-13 Inhibitors as Potential Therapeutic Agents for Osteoarthritis 14
Synthesis and biological evaluation in U87MG glioma cells of (ethynylthiophene)sulfonamido-based hydroxamates as matrix metalloproteinase inhibitors. 14
CXCR4 antagonism sensitizes cancer cells to novel indole-based MDM2/4 inhibitors in glioblastoma multiforme 13
A reverse translational approach reveals the protective roles of Mangifera indica in inflammatory bowel disease 9
Selective Arylsulfonamide Inhibitors of ADAM-17: Hit Optimization and Activity in Ovarian Cancer Cell Models 7
A combined approach of structure‐based virtual screening and NMR to interrupt the PD‐1/PD‐L1 axis: Biphenyl‐benzimidazole containing compounds as novel PD‐L1 inhibitors 4
Development and Nanoparticle-Mediated Delivery of Novel MDM2/MDM4 Heterodimer Peptide Inhibitors to Enhance 5-Fluorouracil Nucleolar Stress in Colorectal Cancer Cells 1
Totale 1.268
Categoria #
all - tutte 5.442
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 5.442


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201911 0 0 0 0 0 0 0 0 0 0 0 11
2019/2020157 59 8 1 1 32 3 4 1 0 14 26 8
2020/2021106 5 1 4 1 2 32 2 10 13 1 25 10
2021/2022226 3 2 4 1 4 1 0 12 51 36 22 90
2022/2023363 42 15 13 34 40 44 0 28 55 60 27 5
2023/2024253 24 26 35 24 18 24 11 35 1 3 43 9
Totale 1.268