IRIS
MICELI, Francesco
 Distribuzione geografica
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Continente #
NA - Nord America 748
EU - Europa 600
AS - Asia 190
AF - Africa 1
Totale 1.539
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Nazione #
US - Stati Uniti d'America 722
IT - Italia 343
CN - Cina 90
NL - Olanda 86
VN - Vietnam 80
IE - Irlanda 34
FI - Finlandia 33
CA - Canada 26
DE - Germania 25
UA - Ucraina 25
SE - Svezia 21
GB - Regno Unito 11
HK - Hong Kong 8
IN - India 8
BE - Belgio 5
GR - Grecia 4
FR - Francia 3
RU - Federazione Russa 3
CH - Svizzera 2
AT - Austria 1
DK - Danimarca 1
EG - Egitto 1
GE - Georgia 1
IL - Israele 1
IS - Islanda 1
KR - Corea 1
SG - Singapore 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 1.539
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Città #
Chandler 168
Dong Ket 80
Millbury 68
Amsterdam 58
Naples 47
Beijing 40
Napoli 40
Princeton 37
Marano di Napoli 35
Jacksonville 30
Des Moines 28
Ottawa 22
Ashburn 20
Formia 19
Breda 16
Trentola-Ducenta 16
Wilmington 15
Boston 14
Lawrence 14
Nanjing 14
Norwalk 11
Hebei 8
Hong Kong 8
Ann Arbor 7
Guangzhou 7
Verona 6
Milan 5
Pozzuoli 5
Redwood City 5
Shenyang 5
Barano d'Ischia 4
Bhopal 4
Boardman 4
Dublin 4
Nanchang 4
Pescara 4
Turin 4
Waanrode 4
Jiaxing 3
Jordanstown 3
Kronberg 3
Moscow 3
Tianjin 3
Vancouver 3
Villaricca 3
Washington 3
Woodbridge 3
Acerra 2
Bisaccia 2
Bolzano 2
Castellammare Di Stabia 2
Changsha 2
Fairfield 2
Indiana 2
Padova 2
Portici 2
Quartu Sant'elena 2
Seregno 2
Shenzhen 2
Stockholm 2
Trieste 2
Witney 2
Altamura 1
Biella 1
Böblingen 1
Cairo 1
Caposele 1
Capua 1
Caserta 1
Casoria 1
Castellammare di Stabia 1
Chengdu 1
Copenhagen 1
Eboli 1
Fisciano 1
Florence 1
Frankfurt am Main 1
Fremont 1
Garching 1
Gelsenkirchen 1
Genoa 1
Genova 1
Giugliano In Campania 1
Lappeenranta 1
Marcianise 1
Nürnberg 1
Orange 1
Perugia 1
Pisa 1
Pune 1
Raleigh 1
Redmond 1
Rehovot 1
Reykjavík 1
Rome 1
Saint-Gilles 1
Sant'Antonio Abate 1
Sant'anastasia 1
Santa Flavia 1
Seattle 1
Totale 975
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Nome #
Decreased subunit stability as a novel mechanism for potassium current impairment by a KCNQ2 C terminus mutation causing benign familial neonatal convulsions 63
A novel hyperekplexia-causing mutation in the pre-trasmembrane segm 1 of the human glycine receptor alpha 1 subunit reduces membrane expression and impairs gating by agonists 58
Involvement of KCNQ2 subunits in [3H]dopamine release triggered by depolarization and pre-synaptic muscarinic receptor activation from rat striatal synaptosomes. 55
Pharmacological Targeting Of Neuronal Kv7.2/3 Channels: A Focus On Chemotypes And Receptor Sites 54
Autism and developmental disability caused by KCNQ3 gain-of-function variants 49
Decreased Subunit Stability as a Novel Mechanismfor PotassiumCurrent Impairment by a KCNQ2 C Terminus Mutation Causing Benign Familial Neonatal Convulsions 47
Early treatment with quinidine in two patients with epilepsy of infancy with migrating focal seizures (EIMFS) due to gain-of-function KCNT1 mutations: functional studies, clinical responses and critical issues for personalized therapy 43
Neuronal potassium channel openers in the management of epilepsy: Role and potential of retigabine 42
Early-onset epileptic encephalopathy caused by gain-of-function mutations in the voltage sensor of Kv7.2 and Kv7.3 potassium channel subunits 41
A novel homozygous KCNQ3 loss-of-function variant causes non-syndromic intellectual disability and neonatal-onset pharmacodependent epilepsy 40
GAIN-OF-FUNCTION DUE TO INCREASED OPENING PROBABILITY BY TWO KCNQ5 PORE VARIANTS CAUSING DEVELOPMENTAL AND/OR EPILEPTIC ENCEPHALOPATHY 40
Driving with no brakes: Molecular pathophysiology of Kv7 potassium channels 39
The voltage-sensing domain of Kv7.2 channels as a molecular target for epilepsy-causing mutations and anticonvulsants 39
Atypical gating of M-type potassium channels conferred by mutations in uncharged residues in the S4 region of KCNQ2 causing benign familial neonatal convulsions. 38
Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate 38
Activation of Kv7 potassium channels inhibits intracellular Ca2+ increases triggered by TRPV1-mediated pain-inducing stimuli in F11 immortalized sensory neurons 38
Insights into the pathogenesis of ATP1A1-related CMT disease using patient-specific iPSCs 38
Synthesis and Pharmacological Characterization of Conformationally Restricted Retigabine Analogues as Novel Neuronal Kv7 Channel Activators 37
Generation of an iPSC line (UNINAi001-A) from a girl with neonatal-onset epilepsy and non-syndromic intellectual disability carrying the homozygous KCNQ3 p.PHE534ILEfs*15 variant and of an iPSC line (UNINAi002-A) from a non-carrier, unaffected brother 36
Functional analysis of novel KCNQ2 and KCNQ3 gene variants found in a large pedigree with benign familial neonatal convulsions (BFNC) 35
Epileptic channelopathies caused by neuronal Kv7 (KCNQ) channel dysfunction 35
Critical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons 33
A novel KCNQ3 mutation in familial epilepsy with focal seizures and intellectual disability 33
Genotype-phenotype correlations in neonatal epilepsies caused by mutations in the voltage sensor of Kv7.2 potassium channel subunits 33
Genotype-phenotype correlations in patients with de novo KCNQ2 pathogenic variants 33
Molecular pathophysiology and pharmacology of the voltage-sensing module of neuronal ion channels 32
Expression and function of Kv7.4 channels in rat cardiac mitochondria: Possible targets for cardioprotection 31
Kv7.3 Compound Heterozygous Variants in Early Onset Encephalopathy Reveal Additive Contribution of C-Terminal Residues to PIP2-Dependent K+ Channel Gating 30
Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity 29
Atypical gating of M-type potassium channels conferred by mutations in uncharged residues in the S4 region of KCNQ2 causing benign familial neonatal convulsions 29
Coupling between the voltage-sensing and phosphatase domains of Ci-VSP 29
Kv7.4 channels regulate potassium permeability in neuronal mitochondria 29
Cardiotoxic effects of antihistamines: From basics to clinics (...and back) 28
Specification of skeletal muscle differentiation by repressor element-1 silencing transcription factor (REST)-regulated Kv7.4 potassium channels 25
Correlating the Clinical and Genetic Features of Benign Familial Neonatal Seizures (BFNS) with the Functional Consequences of Underlying Mutations 25
Human neoplastic mesothelial cells express voltage-gated sodium channels involved in cell motility 24
Epileptic encephalopathy in a patientwith a novel variant in the Kv7.2 S2 transmembrane segment: Clinical, genetic, and functional features 23
KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism 22
Gating currents from Kv7 channels carrying neuronal hyperexcitability mutations in the voltage-sensing domain 22
Infantile spasms and encephalopathy without preceding neonatal seizures caused by KCNQ2 R198Q, a gain-of-function variant 21
Neutralization of a unique, negatively-charged residue in the voltage sensor of KV7.2 subunits in a sporadic case of benign familial neonatal seizures 21
Distinct epilepsy phenotypes and response to drugs in KCNA1 gain- and loss-of function variants 21
Gating consequences of charge neutralization of arginine residues in the S4 segment of K(v)7.2, an epilepsy-linked K+ channel subunit 20
Gating currents from neuronal KV7.4 Channels: General features and correlation with the ionic conductance 18
Molecular pharmacology and therapeutic potential of neuronal Kv7-modulating drugs 18
A Novel Kv7.3 Variant in the Voltage-Sensing S4 Segment in a Family With Benign Neonatal Epilepsy: Functional Characterization and in vitro Rescue by β-Hydroxybutyrate 18
Novel KCNQ2 and KCNQ3 mutations in a large cohort of families with benign neonatal epilepsy: First evidence for an altered channel regulation by syntaxin-1A 16
Vasorelaxation by hydrogen sulphide involves activation of Kv7 potassium channels 16
IKs channels open slowly because KCNE1 accessory subunits slow the movement of S4 voltage sensors in KCNQ1 pore-forming subunits 13
Hyperekplexia caused by dominant-negative suppression of GLYRA1 function 12
Subtype-selective activation of K(v)7 channels by AaTXKβ₂₋₆₄, a novel toxin variant from the Androctonus australis scorpion venom. 10
Personalized stem cell therapy to correct corneal defects due to a unique homozygous-heterozygous mosaicism of ectrodactyly-ectodermal dysplasia-clefting syndrome 10
The Role of Kv7.2 in Neurodevelopment: Insights and Gaps in Our Understanding 4
Phenotypic and functional assessment of two novel KCNQ2 gain-of-function variants Y141N and G239S and effects of amitriptyline treatment 3
Kv7 channel activation reduces brain endothelial cell permeability and prevents kainic acid-induced blood-brain barrier damage 1
Totale 1.637
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Categoria #
all - tutte 6.248
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 6.248
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20194 0 0 0 0 0 0 0 0 0 0 2 2
2019/2020168 42 9 7 1 17 8 12 0 0 29 29 14
2020/2021216 5 6 14 11 11 25 12 15 15 12 10 80
2021/2022310 10 2 1 5 8 4 4 17 40 16 86 117
2022/2023543 56 53 6 111 76 46 6 30 81 58 16 4
2023/2024156 13 30 38 11 14 14 3 14 11 7 1 0
Totale 1.637