MELILLO, ROSA MARINA
MELILLO, ROSA MARINA
DIPARTIMENTO DI MEDICINA MOLECOLARE E BIOTECNOLOGIE MEDICHE
Only the substitution of methionine 918 with a threonine and not with other residues activates RET transforming potential
1997 Cirafici, Am; Salvatore, G; DE VITA, G; Carlomagno, Francesca; Dathan, Na; Visonti, R; Melillo, ROSA MARINA; Fusco, Alfredo; Santoro, M.
Ret-mediated mitogenesis requires Src kinase activity
1999 Melillo, ROSA MARINA; Barone, Mv; Lupoli, G; Cirafici, Am; Carlomagno, Francesca; Visconti, R; Matoskova, B; DI FIORE, Pp; Vecchio, G; Fusco, Alfredo; Santoro, M.
Molecular biology of the MEN2 gene
1998 Santoro, M; Melillo, ROSA MARINA; Carlomagno, Francesca; Visconti, R; DE VITA, Gabriella; Salvatore, G; Lupoli, G; Fusco, Alfredo; Vecchio, G.
Molecular heterogeneity of RET loss of function in Hirschsprung's disease
1996 Carlomagno, Francesca; DE VITA, Gabriella; Berlingieri, Mt; DE FRANCISCIS, V; Melillo, ROSA MARINA; Colantuoni, V; Kraus, Mh; DI FIORE, Pp; Fusco, Alfredo; Santoro, M.
Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2)
2003 Carlomagno, Francesca; Vitagliano, D; Guida, T; Basolo, F; Castellone, Md; Melillo, ROSA MARINA; Fusco, Alfredo; Santoro, Massimo
Tyrosine 1062 of RET-MEN2A mediates activation of Akt (protein kinase B) and mitogen-activated protein kinase pathways leading to PC12 cell survival
2000 DE VITA, Gabriella; Melillo, ROSA MARINA; Carlomagno, Francesca; Visconti, R; Castellone, Md; Bellacosa, A; Billaud, M; Fusco, Alfredo; Tsichlis, Pn; Santoro, M.
Signalling of the Ret receptor tyrosine kinase through the c-Jun N-terminal Protein Kinases (JNKs): evidence for a divergence of the ERKs and JNKs pathways induced by Ret
1998 Chiariello, M; Visconti, R; Carlomagno, Francesca; Melillo, ROSA MARINA; Bucci, C; DE FRANCISCIS, V; Fox, Gm; Jing, S; Coso, Om; Gutkind, Sj; Fusco, Alfredo; Santoro, M.
Molecular defects in thyroid carcinomas: role of the RET oncogene in thyroid neoplastic transformation.
1995 Santoro, Massimo; M., Grieco; Melillo, ROSA MARINA; Fusco, Alfredo; Vecchio, Giancarlo
Molecular mechanisms of RET activation in human neoplasia.
1999 Santoro, Massimo; Carlomagno, Francesca; Melillo, ROSA MARINA; M., Billaud; Vecchio, Giancarlo; Fusco, Alfredo
The different RET-activating capability of mutations of cysteine 620 or cysteine 634 correlates with the multiple endocrine neoplasia type 2 disease phenotype.
1997 Carlomagno, Francesca; G., Salvatore; A. M., Cirafici; DE VITA, Gabriella; Melillo, ROSA MARINA; V. d., Franciscis; M., Billaud; Fusco, Alfredo; Santoro, Massimo
RET/PTC1 oncogene signaling in PC Cl 3 thyroid cells requires the small GTP-binding protein Rho.
2001 Barone, MARIA VITTORIA; Sepe, L; Melillo, ROSA MARINA; Mineo, A; Santelli, G; Monaco, C; Castellone, Md; Tramontano, Donatella; Fusco, Alfredo; Santoro, Massimo
The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway.
2002 Pelicci, G; Troglio, F; Bodini, A; Melillo, ROSA MARINA; Pettirossi, V; Coda, L; DE GIUSEPPE, A; Santoro, Massimo; Pelicci, Pg
Molecular heterogeneity of RET loss of function in Hirschsprung's disease.
1996 Carlomagno, F; DE VITA, G; Berlingieri, Mt; DE FRANCISCIS, V; Melillo, ROSA MARINA; Colantuoni, V; Kraus, Mh; DI FIORE, Pp; Fusco, Alfredo; M., Santoro
The Insulin Receptor Substrate (IRS)-1 recruits Phosphatidylinositol 3-Kinase to Ret: evidence for a competition between Shc and IRS-1 for the binding to Ret.
2001 Melillo, ROSA MARINA; Carlomagno, Francesca; DE VITA, Gabriella; Formisano, Pietro; Vecchio, Giancarlo; Fusco, Alfredo; Billaud, M.; Santoro, Massimo
Potent mitogenicity of the RET/PTC3 oncogene correlates with its prevalence in tall-cell variant of papillary thyroid carcinoma
2002 F., Basolo; R., Giannini; C., Monaco; Melillo, ROSA MARINA; Carlomagno, Francesca; M., Pancrazi; G., Salvatore; G., Chiappetta; F., Pacini; R., Elisei; P., Miccoli; A., Pinchera; Fusco, Alfredo; Santoro, Massimo
Molecular mechanisms of RET activation in human cancer
2002 Santoro, Massimo; Melillo, ROSA MARINA; Carlomagno, F; Fusco, Alfredo; Vecchio, Giancarlo
The docking protein FRS2 links RET and its oncogenic forms with the RAS/MAPK cascade.
2001 Melillo, ROSA MARINA; Santoro, Massimo; S. H., Ong; M., Billaud; Fusco, Alfredo; J., Schlessinger; I., Lax
Ret-mediated mitogenesis requires Src kinase activity.
1999 Melillo, ROSA MARINA; Barone, Mv; Lupoli, G; Cirafici, Am; Carlomagno, F; Visconti, R; Matoskova, B; DI FIORE, Pp; Vecchio, G; Fusco, Alfredo; Santoro, Massimo
Genetic Alterations in differentiated thyroid cancer:what can be expected for gene expression profiling of thyroid carcinomas
2003 Santoro, Massimo; Melillo, ROSA MARINA; Carlomagno, Francesca; Castellone, MARIA DOMENICA; Vitagliano, Donata; Guida, Teresa; Vecchio, Giancarlo; Fusco, Alfredo
Ras-mediated apoptosis of PC CL 3 rat thyroid cells induced by RET/PTC oncogenes.
2003 Castellone, Md; Cirafici, Am; DE VITA, G; DE FALCO, V; Malorni, L; Tallini, G; Fagin, Ja; Fusco, Alfredo; Melillo, ROSA MARINA; Santoro, Massimo
| Titolo | Tipologia | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|---|
| Only the substitution of methionine 918 with a threonine and not with other residues activates RET transforming potential | 1.1 Articolo in rivista | 1997 | Cirafici, Am; Salvatore, G; DE VITA, G; Carlomagno, Francesca; Dathan, Na; Visonti, R; Melillo, ROSA MARINA; Fusco, Alfredo; Santoro, M. | |
| Ret-mediated mitogenesis requires Src kinase activity | 1.1 Articolo in rivista | 1999 | Melillo, ROSA MARINA; Barone, Mv; Lupoli, G; Cirafici, Am; Carlomagno, Francesca; Visconti, R; Matoskova, B; DI FIORE, Pp; Vecchio, G; Fusco, Alfredo; Santoro, M. | |
| Molecular biology of the MEN2 gene | 1.1 Articolo in rivista | 1998 | Santoro, M; Melillo, ROSA MARINA; Carlomagno, Francesca; Visconti, R; DE VITA, Gabriella; Salvatore, G; Lupoli, G; Fusco, Alfredo; Vecchio, G. | |
| Molecular heterogeneity of RET loss of function in Hirschsprung's disease | 1.1 Articolo in rivista | 1996 | Carlomagno, Francesca; DE VITA, Gabriella; Berlingieri, Mt; DE FRANCISCIS, V; Melillo, ROSA MARINA; Colantuoni, V; Kraus, Mh; DI FIORE, Pp; Fusco, Alfredo; Santoro, M. | |
| Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2) | 1.1 Articolo in rivista | 2003 | Carlomagno, Francesca; Vitagliano, D; Guida, T; Basolo, F; Castellone, Md; Melillo, ROSA MARINA; Fusco, Alfredo; Santoro, Massimo | |
| Tyrosine 1062 of RET-MEN2A mediates activation of Akt (protein kinase B) and mitogen-activated protein kinase pathways leading to PC12 cell survival | 1.1 Articolo in rivista | 2000 | DE VITA, Gabriella; Melillo, ROSA MARINA; Carlomagno, Francesca; Visconti, R; Castellone, Md; Bellacosa, A; Billaud, M; Fusco, Alfredo; Tsichlis, Pn; Santoro, M. | |
| Signalling of the Ret receptor tyrosine kinase through the c-Jun N-terminal Protein Kinases (JNKs): evidence for a divergence of the ERKs and JNKs pathways induced by Ret | 1.1 Articolo in rivista | 1998 | Chiariello, M; Visconti, R; Carlomagno, Francesca; Melillo, ROSA MARINA; Bucci, C; DE FRANCISCIS, V; Fox, Gm; Jing, S; Coso, Om; Gutkind, Sj; Fusco, Alfredo; Santoro, M. | |
| Molecular defects in thyroid carcinomas: role of the RET oncogene in thyroid neoplastic transformation. | 1.1 Articolo in rivista | 1995 | Santoro, Massimo; M., Grieco; Melillo, ROSA MARINA; Fusco, Alfredo; Vecchio, Giancarlo | |
| Molecular mechanisms of RET activation in human neoplasia. | 1.1 Articolo in rivista | 1999 | Santoro, Massimo; Carlomagno, Francesca; Melillo, ROSA MARINA; M., Billaud; Vecchio, Giancarlo; Fusco, Alfredo | |
| The different RET-activating capability of mutations of cysteine 620 or cysteine 634 correlates with the multiple endocrine neoplasia type 2 disease phenotype. | 1.1 Articolo in rivista | 1997 | Carlomagno, Francesca; G., Salvatore; A. M., Cirafici; DE VITA, Gabriella; Melillo, ROSA MARINA; V. d., Franciscis; M., Billaud; Fusco, Alfredo; Santoro, Massimo | |
| RET/PTC1 oncogene signaling in PC Cl 3 thyroid cells requires the small GTP-binding protein Rho. | 1.1 Articolo in rivista | 2001 | Barone, MARIA VITTORIA; Sepe, L; Melillo, ROSA MARINA; Mineo, A; Santelli, G; Monaco, C; Castellone, Md; Tramontano, Donatella; Fusco, Alfredo; Santoro, Massimo | |
| The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway. | 1.1 Articolo in rivista | 2002 | Pelicci, G; Troglio, F; Bodini, A; Melillo, ROSA MARINA; Pettirossi, V; Coda, L; DE GIUSEPPE, A; Santoro, Massimo; Pelicci, Pg | |
| Molecular heterogeneity of RET loss of function in Hirschsprung's disease. | 1.1 Articolo in rivista | 1996 | Carlomagno, F; DE VITA, G; Berlingieri, Mt; DE FRANCISCIS, V; Melillo, ROSA MARINA; Colantuoni, V; Kraus, Mh; DI FIORE, Pp; Fusco, Alfredo; M., Santoro | |
| The Insulin Receptor Substrate (IRS)-1 recruits Phosphatidylinositol 3-Kinase to Ret: evidence for a competition between Shc and IRS-1 for the binding to Ret. | 1.1 Articolo in rivista | 2001 | Melillo, ROSA MARINA; Carlomagno, Francesca; DE VITA, Gabriella; Formisano, Pietro; Vecchio, Giancarlo; Fusco, Alfredo; Billaud, M.; Santoro, Massimo | |
| Potent mitogenicity of the RET/PTC3 oncogene correlates with its prevalence in tall-cell variant of papillary thyroid carcinoma | 1.1 Articolo in rivista | 2002 | F., Basolo; R., Giannini; C., Monaco; Melillo, ROSA MARINA; Carlomagno, Francesca; M., Pancrazi; G., Salvatore; G., Chiappetta; F., Pacini; R., Elisei; P., Miccoli; A., Pinchera; Fusco, Alfredo; Santoro, Massimo | |
| Molecular mechanisms of RET activation in human cancer | 2.1 Contributo in volume (Capitolo o Saggio) | 2002 | Santoro, Massimo; Melillo, ROSA MARINA; Carlomagno, F; Fusco, Alfredo; Vecchio, Giancarlo | |
| The docking protein FRS2 links RET and its oncogenic forms with the RAS/MAPK cascade. | 1.1 Articolo in rivista | 2001 | Melillo, ROSA MARINA; Santoro, Massimo; S. H., Ong; M., Billaud; Fusco, Alfredo; J., Schlessinger; I., Lax | |
| Ret-mediated mitogenesis requires Src kinase activity. | 1.1 Articolo in rivista | 1999 | Melillo, ROSA MARINA; Barone, Mv; Lupoli, G; Cirafici, Am; Carlomagno, F; Visconti, R; Matoskova, B; DI FIORE, Pp; Vecchio, G; Fusco, Alfredo; Santoro, Massimo | |
| Genetic Alterations in differentiated thyroid cancer:what can be expected for gene expression profiling of thyroid carcinomas | 1.1 Articolo in rivista | 2003 | Santoro, Massimo; Melillo, ROSA MARINA; Carlomagno, Francesca; Castellone, MARIA DOMENICA; Vitagliano, Donata; Guida, Teresa; Vecchio, Giancarlo; Fusco, Alfredo | |
| Ras-mediated apoptosis of PC CL 3 rat thyroid cells induced by RET/PTC oncogenes. | 1.1 Articolo in rivista | 2003 | Castellone, Md; Cirafici, Am; DE VITA, G; DE FALCO, V; Malorni, L; Tallini, G; Fagin, Ja; Fusco, Alfredo; Melillo, ROSA MARINA; Santoro, Massimo |