: During COVID-19 pandemic, a lot of diseases suffered from a limited access to health care services, owing to the use of resources, both technical and financial, mainly directed towards such a dramatic outbreak. Among these, tuberculosis (TB) has been one of the most penalized, with a huge delay both in diagnosis and in start of treatment, with a consequential dramatic increase in morbidity and mortality. COVID-19 and tuberculosis share similar common pathogenetic pathways, and both diseases affect primarily the lungs. About the impact of TB on COVID-19 severity and mortality, data are unclear and literature reports are often conflicting. Certainly, considering the management of coinfected patients, there are pharmacokinetic interactions between several drugs used for the therapy of SARS-CoV-2 infection and the treatment of TB.

Clinical impact of COVID-19 on tuberculosis / Sanduzzi Zamparelli, Stefano.; Mormile, Mauro; Sanduzzi Zamparelli, Alessandro.; Guarino, Amedeo; Parrella, Roberto; Bocchino, M.. - In: LE INFEZIONI IN MEDICINA. - ISSN 1124-9390. - 30:4(2022), pp. 495-500. [10.53854/liim-3004-3]

Clinical impact of COVID-19 on tuberculosis

Mormile Mauro
Secondo
;
Sanduzzi Zamparelli Alessandro.;Guarino Amedeo;Parrella Roberto;Bocchino M.
2022

Abstract

: During COVID-19 pandemic, a lot of diseases suffered from a limited access to health care services, owing to the use of resources, both technical and financial, mainly directed towards such a dramatic outbreak. Among these, tuberculosis (TB) has been one of the most penalized, with a huge delay both in diagnosis and in start of treatment, with a consequential dramatic increase in morbidity and mortality. COVID-19 and tuberculosis share similar common pathogenetic pathways, and both diseases affect primarily the lungs. About the impact of TB on COVID-19 severity and mortality, data are unclear and literature reports are often conflicting. Certainly, considering the management of coinfected patients, there are pharmacokinetic interactions between several drugs used for the therapy of SARS-CoV-2 infection and the treatment of TB.
2022
Clinical impact of COVID-19 on tuberculosis / Sanduzzi Zamparelli, Stefano.; Mormile, Mauro; Sanduzzi Zamparelli, Alessandro.; Guarino, Amedeo; Parrella, Roberto; Bocchino, M.. - In: LE INFEZIONI IN MEDICINA. - ISSN 1124-9390. - 30:4(2022), pp. 495-500. [10.53854/liim-3004-3]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/923035
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