Background: Left lateral sectionectomy (LLS) is one of the most commonly performed minimally invasive liver resections. While laparoscopic (L)-LLS is a well-established technique, over traditional open resection, it remains controversial if robotic (R)-LLS provides any advantages of L-LLS. Methods: A post hoc analysis of 997 patients from 21 international centres undergoing L-LLS or R-LLS from 2006 to 2020 was conducted. A total of 886 cases (214 R-LLS, 672 L-LLS) met study criteria. 1:1 and 1:2 propensity score matched (PSM) comparison was performed between R-LLS & L-LLS. Further subset analysis by Iwate difficulty was also performed. Outcomes measured include operating time, blood loss, open conversion, readmission rates, morbidity and mortality. Results: Comparison between R-LLS and L-LLS after PSM 1:2 demonstrated statistically significantly lower open conversion rate in R-LLS than L-LLS (0.6% versus 5%, p = 0.009) and median blood loss was also statistically significantly lower in R-LLS at 50 (80) versus 100 (170) in L-LLS (p = 0.011) after PSM 1:1 although there was no difference in the blood transfusion rate. Pringle manoeuvre was also found to be used more frequently in R-LLS, with 53(24.8%) cases versus to 84(12.5%) L-LLS cases (p < 0.001). There was no significant difference in the other key perioperative outcomes such as operating time, length of stay, postoperative morbidity, major morbidity and 90-day mortality between both groups. Conclusion: R-LLS was associated with similar key perioperative outcomes compared to L-LLS. It was also associated with significantly lower blood loss and open conversion rates compared to L-LLS.

An international multicentre propensity score matched analysis comparing between robotic versus laparoscopic left lateral sectionectomy / Chong, Y.; Prieto, M.; Gastaca, M.; Choi, S. -H.; Sucandy, I.; Chiow, A. K. H.; Marino, M. V.; Wang, X.; Efanov, M.; Schotte, H.; D'Hondt, M.; Choi, G. -H.; Krenzien, F.; Schmelzle, M.; Pratschke, J.; Kingham, T. P.; Giglio, M.; Troisi, R.; Lee, J. H.; Lai, E. C.; Tang, C. N.; Fuks, D.; D'Silva, M.; Han, H. -S.; Kadam, P.; Sutcliffe, R. P.; Lee, K. -F.; Chong, C. C.; Cheung, T. -T.; Liu, Q.; Liu, R.; Goh, B. K. P.; Chan, C. -Y.; De Meyere, C.; Salimgereeva, D.; Alikhanov, R.; Lee, L. -S.; Jang, J. Y.; Montalti, R.. - In: SURGICAL ENDOSCOPY. - ISSN 0930-2794. - (2022). [10.1007/s00464-022-09790-x]

An international multicentre propensity score matched analysis comparing between robotic versus laparoscopic left lateral sectionectomy

Giglio M.
Membro del Collaboration Group
;
Troisi R.;Montalti R.
2022

Abstract

Background: Left lateral sectionectomy (LLS) is one of the most commonly performed minimally invasive liver resections. While laparoscopic (L)-LLS is a well-established technique, over traditional open resection, it remains controversial if robotic (R)-LLS provides any advantages of L-LLS. Methods: A post hoc analysis of 997 patients from 21 international centres undergoing L-LLS or R-LLS from 2006 to 2020 was conducted. A total of 886 cases (214 R-LLS, 672 L-LLS) met study criteria. 1:1 and 1:2 propensity score matched (PSM) comparison was performed between R-LLS & L-LLS. Further subset analysis by Iwate difficulty was also performed. Outcomes measured include operating time, blood loss, open conversion, readmission rates, morbidity and mortality. Results: Comparison between R-LLS and L-LLS after PSM 1:2 demonstrated statistically significantly lower open conversion rate in R-LLS than L-LLS (0.6% versus 5%, p = 0.009) and median blood loss was also statistically significantly lower in R-LLS at 50 (80) versus 100 (170) in L-LLS (p = 0.011) after PSM 1:1 although there was no difference in the blood transfusion rate. Pringle manoeuvre was also found to be used more frequently in R-LLS, with 53(24.8%) cases versus to 84(12.5%) L-LLS cases (p < 0.001). There was no significant difference in the other key perioperative outcomes such as operating time, length of stay, postoperative morbidity, major morbidity and 90-day mortality between both groups. Conclusion: R-LLS was associated with similar key perioperative outcomes compared to L-LLS. It was also associated with significantly lower blood loss and open conversion rates compared to L-LLS.
2022
An international multicentre propensity score matched analysis comparing between robotic versus laparoscopic left lateral sectionectomy / Chong, Y.; Prieto, M.; Gastaca, M.; Choi, S. -H.; Sucandy, I.; Chiow, A. K. H.; Marino, M. V.; Wang, X.; Efanov, M.; Schotte, H.; D'Hondt, M.; Choi, G. -H.; Krenzien, F.; Schmelzle, M.; Pratschke, J.; Kingham, T. P.; Giglio, M.; Troisi, R.; Lee, J. H.; Lai, E. C.; Tang, C. N.; Fuks, D.; D'Silva, M.; Han, H. -S.; Kadam, P.; Sutcliffe, R. P.; Lee, K. -F.; Chong, C. C.; Cheung, T. -T.; Liu, Q.; Liu, R.; Goh, B. K. P.; Chan, C. -Y.; De Meyere, C.; Salimgereeva, D.; Alikhanov, R.; Lee, L. -S.; Jang, J. Y.; Montalti, R.. - In: SURGICAL ENDOSCOPY. - ISSN 0930-2794. - (2022). [10.1007/s00464-022-09790-x]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/905683
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