This study introduces a newly created strain (Rhodococcus equiEtBr25) by exposing R. equi ATCC 33701 to ethidium bromide (EtBr), a substrate for MDR transporters. Such an approach allowed us to investigate the resulting phenotype and genetic mechanisms underlying the efflux-mediated resistance in R. equi.
Ethidium bromide exposure unmasks an antibiotic efflux system in Rhodococcus equi / Rampacci, Elisa; Marenzoni, Maria Luisa; Cannalire, Rolando; Pietrella, Donatella; Sabatini, Stefano; Giovagnoli, Stefano; Felicetti, Tommaso; Pepe, Marco; Passamonti, Fabrizio. - In: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. - ISSN 1460-2091. - 76:8(2021), pp. 2040-2048. [10.1093/jac/dkab121]
Ethidium bromide exposure unmasks an antibiotic efflux system in Rhodococcus equi
Cannalire, Rolando;
2021
Abstract
This study introduces a newly created strain (Rhodococcus equiEtBr25) by exposing R. equi ATCC 33701 to ethidium bromide (EtBr), a substrate for MDR transporters. Such an approach allowed us to investigate the resulting phenotype and genetic mechanisms underlying the efflux-mediated resistance in R. equi.| File | Dimensione | Formato | |
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