The limited therapeutic options for ischemic stroke treatment render necessary the identification of new strategies. In recent years, it has been shown that natural compounds may represent a valid therapeutic opportunity. Therefore, the present study aimed to evaluate the protective effect of Ruta graveolens water extract (RGWE) in an in vivo experimental model of brain ischemia.
Ruta graveolens water extract (RGWE) ameliorates ischemic damage and improves neurological deficits in a rat model of transient focal brain ischemia / Campanile, Mario; Cuomo, Ornella; Brancaccio, Paola; Vinciguerra, Antonio; Casamassa, Antonella; Pastorino, Olga; Volpicelli, Floriana; Gentile, Maria Teresa; Amoroso, Salvatore; Annunziato, Lucio; Colucci-D Amato, Luca; Pignataro, Giuseppe. - In: BIOMÉDECINE & PHARMACOTHÉRAPIE. - ISSN 0753-3322. - 154:(2022), p. 113587. [10.1016/j.biopha.2022.113587]
Ruta graveolens water extract (RGWE) ameliorates ischemic damage and improves neurological deficits in a rat model of transient focal brain ischemia
Campanile, Mario;Cuomo, Ornella;Brancaccio, Paola;Vinciguerra, Antonio;Casamassa, Antonella;Volpicelli, Floriana;Annunziato, Lucio;Pignataro, Giuseppe
2022
Abstract
The limited therapeutic options for ischemic stroke treatment render necessary the identification of new strategies. In recent years, it has been shown that natural compounds may represent a valid therapeutic opportunity. Therefore, the present study aimed to evaluate the protective effect of Ruta graveolens water extract (RGWE) in an in vivo experimental model of brain ischemia.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
