Aim: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus-specific reverse transcriptase-polymerase chain reaction (RT-PCR) represents the diagnostic gold standard. We explored the value of chest ultrasonography to predict positivity to SARS-CoV-2 on RT-PCR in suspected COVID-19 cases. Patients & methods: Consecutive patients with suspect COVID-19 were included if they had fever and/or history of cough and/or dyspnea. Lung ultrasound score (LUSS) was computed according to published methods. Results: A total of 76 patients were included. A 3-variable model based on aspartate transaminase (AST) > upper limit of normal, LUSS >12 and body temperature >37.5°C yielded an overall accuracy of 91%. Conclusion: A simple LUSS-based model may represent a powerful tool for initial assessment in suspected cases of COVID-19. The gold standard for diagnosis of COVID-19 is RT-PCR. During a pandemic emergency, it may be useful to identify suspect symptomatic patients who may safely be observed without undergoing testing for COVID-19. In this work, a simple model based on the findings of lung ultrasound, AST levels and fever showed an overall accuracy of 91% to predict the results of RT-PCR.

The use of chest ultrasonography in suspected cases of COVID-19 in the emergency department / Allegorico, E.; Buonerba, C.; Bosso, G.; Pagano, A.; Porta, G.; Serra, C.; Dolce, P.; Minerva, V.; Vicario, F. D.; Altruda, C.; Arbo, P.; Russo, T.; Sio, C. D.; Franco, N.; Ruffa, G.; Mormile, C.; Cannavacciuolo, F.; Mercurio, V.; Gervasio, G.; Costanzo, G. D.; Ragozzino, A.; Scafuri, L.; Facchini, G.; Numis, F.. - In: FUTURE SCIENCE OA. - ISSN 2056-5623. - 7:1(2021), p. FSO635. [10.2144/fsoa-2020-0127]

The use of chest ultrasonography in suspected cases of COVID-19 in the emergency department

Buonerba C.;Bosso G.;Serra C.;Dolce P.;Minerva V.;Franco N.;Mormile C.;Mercurio V.;Ragozzino A.;Scafuri L.;Facchini G.;
2021

Abstract

Aim: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus-specific reverse transcriptase-polymerase chain reaction (RT-PCR) represents the diagnostic gold standard. We explored the value of chest ultrasonography to predict positivity to SARS-CoV-2 on RT-PCR in suspected COVID-19 cases. Patients & methods: Consecutive patients with suspect COVID-19 were included if they had fever and/or history of cough and/or dyspnea. Lung ultrasound score (LUSS) was computed according to published methods. Results: A total of 76 patients were included. A 3-variable model based on aspartate transaminase (AST) > upper limit of normal, LUSS >12 and body temperature >37.5°C yielded an overall accuracy of 91%. Conclusion: A simple LUSS-based model may represent a powerful tool for initial assessment in suspected cases of COVID-19. The gold standard for diagnosis of COVID-19 is RT-PCR. During a pandemic emergency, it may be useful to identify suspect symptomatic patients who may safely be observed without undergoing testing for COVID-19. In this work, a simple model based on the findings of lung ultrasound, AST levels and fever showed an overall accuracy of 91% to predict the results of RT-PCR.
2021
The use of chest ultrasonography in suspected cases of COVID-19 in the emergency department / Allegorico, E.; Buonerba, C.; Bosso, G.; Pagano, A.; Porta, G.; Serra, C.; Dolce, P.; Minerva, V.; Vicario, F. D.; Altruda, C.; Arbo, P.; Russo, T.; Sio, C. D.; Franco, N.; Ruffa, G.; Mormile, C.; Cannavacciuolo, F.; Mercurio, V.; Gervasio, G.; Costanzo, G. D.; Ragozzino, A.; Scafuri, L.; Facchini, G.; Numis, F.. - In: FUTURE SCIENCE OA. - ISSN 2056-5623. - 7:1(2021), p. FSO635. [10.2144/fsoa-2020-0127]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/858364
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