SUMMARY Obstructive sleep apnoea/hypopnoea syndrome (OSAHS) is a disease characterised by upper airway obstruction during sleep, quite frequent in the general population, even if underestimated. Snoring, sleep apnoea and diurnal hypersomnia are common in these patients. Central obesity plays a key role: it reduces the size and changes the conformation of the upper airways, besides preventing lung expansion, with consequent reduction of lung volumes. Furthermore, obese people are also resistant to leptin, which physiologically stimulates ventilation; as a result, this causes scarce awakening during apnoea. OSAHS diagnosis is based on the combination of clinical parameters, such as apnoea/hypopnoea index (AHI), medical history, physical examination and Mallampati score. The first objective reference method to identify OSAHS is polysomnography followed by sleep endoscopy. Therapy provides in the first instance reduction of body weight, followed by continuous positive airway pressure (CPAP), which still remains the treatment of choice in most patients, mandibular advancement devices (MAD) and finally otolaryngology or maxillofacial surgery. Among surgical techniques, central is barbed reposition pharyngoplasty (BRP), used in the field of multilevel surgery.

Obstructive sleep apnoea/hypopnoea syndrome: Relationship with obesity and management in obese patients / Salzano, G.; Maglitto, F.; Bisogno, A.; Vaira, L. A.; De Riu, G.; Cavaliere, M.; Di Stadio, A.; Mesolella, M.; Motta, G.; Ionna, F.; Califano, L.; Salzano, F. A.. - In: ACTA OTORHINOLARYNGOLOGICA ITALICA. - ISSN 0392-100X. - 41:2(2021), pp. 120-130. [10.14639/0392-100X-N1100]

Obstructive sleep apnoea/hypopnoea syndrome: Relationship with obesity and management in obese patients

Maglitto F.;Vaira L. A.;De Riu G.;Mesolella M.;Motta G.;Califano L.;
2021

Abstract

SUMMARY Obstructive sleep apnoea/hypopnoea syndrome (OSAHS) is a disease characterised by upper airway obstruction during sleep, quite frequent in the general population, even if underestimated. Snoring, sleep apnoea and diurnal hypersomnia are common in these patients. Central obesity plays a key role: it reduces the size and changes the conformation of the upper airways, besides preventing lung expansion, with consequent reduction of lung volumes. Furthermore, obese people are also resistant to leptin, which physiologically stimulates ventilation; as a result, this causes scarce awakening during apnoea. OSAHS diagnosis is based on the combination of clinical parameters, such as apnoea/hypopnoea index (AHI), medical history, physical examination and Mallampati score. The first objective reference method to identify OSAHS is polysomnography followed by sleep endoscopy. Therapy provides in the first instance reduction of body weight, followed by continuous positive airway pressure (CPAP), which still remains the treatment of choice in most patients, mandibular advancement devices (MAD) and finally otolaryngology or maxillofacial surgery. Among surgical techniques, central is barbed reposition pharyngoplasty (BRP), used in the field of multilevel surgery.
2021
Obstructive sleep apnoea/hypopnoea syndrome: Relationship with obesity and management in obese patients / Salzano, G.; Maglitto, F.; Bisogno, A.; Vaira, L. A.; De Riu, G.; Cavaliere, M.; Di Stadio, A.; Mesolella, M.; Motta, G.; Ionna, F.; Califano, L.; Salzano, F. A.. - In: ACTA OTORHINOLARYNGOLOGICA ITALICA. - ISSN 0392-100X. - 41:2(2021), pp. 120-130. [10.14639/0392-100X-N1100]
File in questo prodotto:
File Dimensione Formato  
OSAS Salzano-2021-Obstructive-sleep-apnoea-hypopnoea-.pdf

accesso aperto

Tipologia: Versione Editoriale (PDF)
Licenza: Dominio pubblico
Dimensione 522.8 kB
Formato Adobe PDF
522.8 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/852976
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 15
  • ???jsp.display-item.citation.isi??? 10
social impact