Harzianic acid is a secondary metabolite of Trichoderma, structurally belonging to the dienyltetramic acid subgroup of the tetramic acids. Biological activities of harzianic acid are of great interest for its antimicrobial and plant growth-promoting activities, which might be related to its chelating properties. In the present work harzianic acid, isolated from cultures of a strain of Trichoderma pleuroticola associated to the gastropod Melarhaphe neritoides, was studied as a complexant agent of a number of biologically relevant transition metals (i.e., Zn2+, Fe2+, Cu2+, and Mn2+), using UV-VIS, potentiometry, MS and NMR techniques. Our findings show the coordination capacity of harzianic acid toward the above cations through the formation of neutral or charged complexes in a variable ratio depending on the metal and pH conditions.

Bivalent metal-chelating properties of harzianic acid produced by Trichoderma pleuroticola associated to the gastropod Melarhaphe neritoides / De Tommaso, G.; Salvatore, M. M.; Nicoletti, R.; Della Greca, M.; Vinale, F.; Bottiglieri, A.; Staropoli, A.; Salvatore, F.; Lorito, M.; Iuliano, M.; Andolfi, A.. - In: MOLECULES. - ISSN 1420-3049. - 25:9(2020), pp. 2147-N/A. [10.3390/molecules25092147]

Bivalent metal-chelating properties of harzianic acid produced by Trichoderma pleuroticola associated to the gastropod Melarhaphe neritoides

De Tommaso G.
Writing – Original Draft Preparation
;
Salvatore M. M.
Investigation
;
Nicoletti R.
Membro del Collaboration Group
;
Della Greca M.
Formal Analysis
;
Vinale F.
Data Curation
;
Bottiglieri A.
Formal Analysis
;
Staropoli A.
Investigation
;
Salvatore F.
Data Curation
;
Lorito M.
Visualization
;
Iuliano M.
Data Curation
;
Andolfi A.
Writing – Review & Editing
2020

Abstract

Harzianic acid is a secondary metabolite of Trichoderma, structurally belonging to the dienyltetramic acid subgroup of the tetramic acids. Biological activities of harzianic acid are of great interest for its antimicrobial and plant growth-promoting activities, which might be related to its chelating properties. In the present work harzianic acid, isolated from cultures of a strain of Trichoderma pleuroticola associated to the gastropod Melarhaphe neritoides, was studied as a complexant agent of a number of biologically relevant transition metals (i.e., Zn2+, Fe2+, Cu2+, and Mn2+), using UV-VIS, potentiometry, MS and NMR techniques. Our findings show the coordination capacity of harzianic acid toward the above cations through the formation of neutral or charged complexes in a variable ratio depending on the metal and pH conditions.
2020
Bivalent metal-chelating properties of harzianic acid produced by Trichoderma pleuroticola associated to the gastropod Melarhaphe neritoides / De Tommaso, G.; Salvatore, M. M.; Nicoletti, R.; Della Greca, M.; Vinale, F.; Bottiglieri, A.; Staropoli, A.; Salvatore, F.; Lorito, M.; Iuliano, M.; Andolfi, A.. - In: MOLECULES. - ISSN 1420-3049. - 25:9(2020), pp. 2147-N/A. [10.3390/molecules25092147]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/830286
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 15
  • ???jsp.display-item.citation.isi??? 13
social impact