Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia together with disturbances in the metabolism of carbohydrates, proteins and fat, which in general results from an insulin availability and need imbalance. In a great number of patients, marketed anti-glycemic agents have shown poor effectiveness in maintaining a long-term glycemic control, thus being associated with severe adverse effects and leading to an emerging interest in natural compounds (e.g., essential oils and other secondary plant metabolites, namely, flavonoid-rich compounds) as a novel approach for prevention, management and/or treatment of either non-insulin-dependent diabetes mellitus (T2DM, type 2 DM) and/or Metabolic Syndrome (MS). In this review, some of these promising glucose-lowering agents will be comprehensively discussed.

Sugar-lowering drugs for type 2 diabetes mellitus and metabolic syndrome—review of classical and new compounds: Part-i / Vieira, R.; Souto, S. B.; Sanchez-Lopez, E.; Machado, A. L.; Severino, P.; Jose, S.; Santini, A.; Fortuna, A.; Garcia, M. L.; Silva, A. M.; Souto, E. B.. - In: PHARMACEUTICALS. - ISSN 1424-8247. - 12:4(2019), p. 152. [10.3390/ph12040152]

Sugar-lowering drugs for type 2 diabetes mellitus and metabolic syndrome—review of classical and new compounds: Part-i

Santini A.;
2019

Abstract

Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia together with disturbances in the metabolism of carbohydrates, proteins and fat, which in general results from an insulin availability and need imbalance. In a great number of patients, marketed anti-glycemic agents have shown poor effectiveness in maintaining a long-term glycemic control, thus being associated with severe adverse effects and leading to an emerging interest in natural compounds (e.g., essential oils and other secondary plant metabolites, namely, flavonoid-rich compounds) as a novel approach for prevention, management and/or treatment of either non-insulin-dependent diabetes mellitus (T2DM, type 2 DM) and/or Metabolic Syndrome (MS). In this review, some of these promising glucose-lowering agents will be comprehensively discussed.
2019
Sugar-lowering drugs for type 2 diabetes mellitus and metabolic syndrome—review of classical and new compounds: Part-i / Vieira, R.; Souto, S. B.; Sanchez-Lopez, E.; Machado, A. L.; Severino, P.; Jose, S.; Santini, A.; Fortuna, A.; Garcia, M. L.; Silva, A. M.; Souto, E. B.. - In: PHARMACEUTICALS. - ISSN 1424-8247. - 12:4(2019), p. 152. [10.3390/ph12040152]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/768895
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